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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS) (Chlorobium tepidum)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCTEP194439:G1FZE-15-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:CT0015
OrganismiChlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS) (Chlorobium tepidum)
Taxonomic identifieri194439 [NCBI]
Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChlorobaculum
Proteomesi
  • UP000001007 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001515471 – 551Arginine--tRNA ligaseAdd BLAST551

Proteomic databases

PRIDEiQ8KGF3

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi194439.CT0015

Structurei

3D structure databases

ProteinModelPortaliQ8KGF3
SMRiQ8KGF3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi123 – 133"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247214
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit

Sequencei

Sequence statusi: Complete.

Q8KGF3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRAFFLPFIQ DALQKAGIET DKEIQIDKPN DKKFGDFSTN IAFLVAKEAR
60 70 80 90 100
KNPRELAGQL IGLLDFPEGT VTKTEVAGPG FINFHLAPAF FMRSAQEVLA
110 120 130 140 150
KGEGFGCNES GKGLKAIVEY VSANPTGPLT IGRGRGGVLG DCIANLLETQ
160 170 180 190 200
GYEVTREYYF NDAGRQMQIL AESVRYRYLE KCGQVIEFPE THYQGDYIGE
210 220 230 240 250
IAETLFIEHG DGLAATDELT IFKEAAEAVI FSSIRKTLER LLITHDSFFN
260 270 280 290 300
EHTLYQSREG QPSANQRVID ALDAKGFIGN YDGATWFMTT KLGQEKDKVL
310 320 330 340 350
IKSSGDPSYR LPDIAYHVTK FERGFDLMVN VFGADHIDEY PDVLEALKIL
360 370 380 390 400
GYDTSKVKIA INQFVTTTVG GQTVKMSTRK GNADLLDDLI DDVGADATRL
410 420 430 440 450
FFIMRGKDSH LNFDVELAKK QSKDNPVFYL QYAHARICSL VRMAEKEVGF
460 470 480 490 500
DEATAIGAGL PLLSSEPEID LASALLDFPD IIQSSLRQLE PQKMVEYLHT
510 520 530 540 550
VAERYHKFYQ ECPILKADEH LRTARLELSL AVRQVLRNGF KILGISAPES

M
Length:551
Mass (Da):61,453
Last modified:October 1, 2002 - v1
Checksum:i9DE21B52718C680E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006470 Genomic DNA Translation: AAM71263.1
RefSeqiNP_660921.1, NC_002932.3
WP_010931709.1, NC_002932.3

Genome annotation databases

EnsemblBacteriaiAAM71263; AAM71263; CT0015
GeneIDi1006182
KEGGicte:CT0015
PATRICifig|194439.7.peg.14

Similar proteinsi

Entry informationi

Entry nameiSYR_CHLTE
AccessioniPrimary (citable) accession number: Q8KGF3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 22, 2003
Last sequence update: October 1, 2002
Last modified: March 28, 2018
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

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