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Entry version 141 (12 Aug 2020)
Sequence version 3 (23 Jan 2007)
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Protein

High mobility group protein HMG-I/HMG-Y

Gene

Hmga1

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double-stranded DNA. It is suggested that these proteins could function in nucleosome phasing and in the 3'-end processing of mRNA transcripts. They are also involved in the transcription regulation of genes containing, or in close proximity to A+T-rich regions (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position and type of each DNA-binding domain present within the protein.<p><a href='/help/dna_bind' target='_top'>More...</a></p>DNA bindingi21 – 31A.T hook 1Add BLAST11
DNA bindingi53 – 63A.T hook 2Add BLAST11
DNA bindingi78 – 89A.T hook 3Add BLAST12

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-RNO-2559584, Formation of Senescence-Associated Heterochromatin Foci (SAHF)

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
High mobility group protein HMG-I/HMG-Y
Short name:
HMG-I(Y)
Alternative name(s):
High mobility group AT-hook protein 1
Short name:
High mobility group protein A1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Hmga1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 20

Organism-specific databases

Rat genome database

More...
RGDi
628699, Hmga1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedBy similarity
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002067102 – 107High mobility group protein HMG-I/HMG-YAdd BLAST106

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylserineBy similarity1
Modified residuei7N6-acetyllysineBy similarity1
Modified residuei8ADP-ribosylserineBy similarity1
Modified residuei9ADP-ribosylserine; alternateBy similarity1
Modified residuei9Phosphoserine; alternateBy similarity1
Modified residuei15N6-acetyllysine; alternateBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki15Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateBy similarity
Modified residuei26Asymmetric dimethylarginine; alternateBy similarity1
Modified residuei26Omega-N-methylarginine; alternateBy similarity1
Modified residuei26Symmetric dimethylarginine; alternateBy similarity1
Modified residuei36Phosphoserine; by HIPK2 and CDC2By similarity1
Modified residuei39PhosphothreonineBy similarity1
Modified residuei44PhosphoserineBy similarity1
Modified residuei49PhosphoserineBy similarity1
Modified residuei53Phosphothreonine; by HIPK2 and CDC2By similarity1
Modified residuei58Asymmetric dimethylarginine; by PRMT6; alternateBy similarity1
Modified residuei58Omega-N-methylarginine; by PRMT6; alternateBy similarity1
Modified residuei60Asymmetric dimethylarginine; by PRMT6; alternateBy similarity1
Modified residuei60Omega-N-methylarginine; by PRMT6; alternateBy similarity1
Modified residuei78Phosphothreonine; by HIPK2 and CDC2By similarity1
Modified residuei99PhosphoserineBy similarity1
Modified residuei102PhosphoserineBy similarity1
Modified residuei103PhosphoserineBy similarity1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Isoforms HMG-I and HMG-Y can be phosphorylated by HIPK2. Phosphorylation may modulate DNA-binding affinity (By similarity).By similarity
Methylation at Arg-58 is mutually exclusive with methylation at Arg-60.By similarity

Keywords - PTMi

Acetylation, ADP-ribosylation, Isopeptide bond, Methylation, Phosphoprotein, Ubl conjugation

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8K585

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8K585

PRoteomics IDEntifications database

More...
PRIDEi
Q8K585

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8K585

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8K585

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSRNOG00000000488, Expressed in thymus and 21 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with HIPK2.

By similarity

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
250659, 1 interactor

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q8K585

STRING: functional protein association networks

More...
STRINGi
10116.ENSRNOP00000000580

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8K585

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni53 – 77Interaction with HIPK2By similarityAdd BLAST25

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi91 – 106Glu-rich (acidic)Add BLAST16

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the HMGA family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502S5JW, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00730000111329

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_138888_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8K585

KEGG Orthology (KO)

More...
KOi
K09282

Identification of Orthologs from Complete Genome Data

More...
OMAi
FCEEASG

Database of Orthologous Groups

More...
OrthoDBi
1603551at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8K585

TreeFam database of animal gene trees

More...
TreeFami
TF351623

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR017956, AT_hook_DNA-bd_motif
IPR000116, HMGA
IPR031079, HMGA1_mammal
IPR000637, HMGI/Y_DNA-bd_CS

The PANTHER Classification System

More...
PANTHERi
PTHR23341:SF6, PTHR23341:SF6, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02178, AT_hook, 3 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00929, ATHOOK
PR00930, HIGHMOBLTYIY

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00384, AT_hook, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00354, HMGI_Y, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform HMG-I (identifier: Q8K585-1) [UniParc]FASTAAdd to basket
Also known as: HMGA1a

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSESVSKSSQ PLASKQEKDG TEKRGRGRPR KQPSVSPGTA LVGSQKEPSE
60 70 80 90 100
VPTPKRPRGR PKGSKNKGTA KTRKVTTTPG RKPRGRPKKL EKEEEEGISQ

ESSEEEQ
Length:107
Mass (Da):11,706
Last modified:January 23, 2007 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0F944B183384C10E
GO
Isoform HMG-Y (identifier: Q8K585-2) [UniParc]FASTAAdd to basket
Also known as: HMGA1b

The sequence of this isoform differs from the canonical sequence as follows:
     35-45: Missing.

Show »
Length:96
Mass (Da):10,709
Checksum:i1C685D17CB68561D
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti5V → G in AAM33433 (Ref. 2) Curated1

<p>This subsection of the 'Sequence' section reports information derived from mass spectrometry experiments done on the entire protein or on biologically active derived peptide(s).<p><a href='/help/mass_spectrometry' target='_top'>More...</a></p>Mass spectrometryi

Molecular mass is 11776.8±1 Da. Determined by MALDI. With 1 acetyl and 2 phosphate groups.1 Publication
Molecular mass is 11856.8±1 Da. Determined by MALDI. With 1 acetyl and 3 phosphate groups.1 Publication
Molecular mass is 11791.2±1 Da. Determined by MALDI. With 1 acetyl, 1 methyl and 2 phosphate groups.1 Publication
Molecular mass is 11871.3±1 Da. Determined by MALDI. With 1 acetyl, 1 methyl and 3 phosphate groups.1 Publication

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_01639535 – 45Missing in isoform HMG-Y. 1 PublicationAdd BLAST11

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF511040 mRNA Translation: AAM74157.1
AF507966 mRNA Translation: AAM33433.1

NCBI Reference Sequences

More...
RefSeqi
NP_647543.1, NM_139327.1
XP_006256218.1, XM_006256156.2 [Q8K585-1]
XP_006256219.1, XM_006256157.3 [Q8K585-1]
XP_006256220.1, XM_006256158.3 [Q8K585-1]
XP_006256224.1, XM_006256162.3 [Q8K585-2]
XP_006256225.1, XM_006256163.3 [Q8K585-2]
XP_017457021.1, XM_017601532.1 [Q8K585-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSRNOT00000000580; ENSRNOP00000000580; ENSRNOG00000000488 [Q8K585-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
117062

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
rno:117062

UCSC genome browser

More...
UCSCi
RGD:628699, rat [Q8K585-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF511040 mRNA Translation: AAM74157.1
AF507966 mRNA Translation: AAM33433.1
RefSeqiNP_647543.1, NM_139327.1
XP_006256218.1, XM_006256156.2 [Q8K585-1]
XP_006256219.1, XM_006256157.3 [Q8K585-1]
XP_006256220.1, XM_006256158.3 [Q8K585-1]
XP_006256224.1, XM_006256162.3 [Q8K585-2]
XP_006256225.1, XM_006256163.3 [Q8K585-2]
XP_017457021.1, XM_017601532.1 [Q8K585-2]

3D structure databases

SMRiQ8K585
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi250659, 1 interactor
CORUMiQ8K585
STRINGi10116.ENSRNOP00000000580

PTM databases

iPTMnetiQ8K585
PhosphoSitePlusiQ8K585

Proteomic databases

jPOSTiQ8K585
PaxDbiQ8K585
PRIDEiQ8K585

Genome annotation databases

EnsembliENSRNOT00000000580; ENSRNOP00000000580; ENSRNOG00000000488 [Q8K585-1]
GeneIDi117062
KEGGirno:117062
UCSCiRGD:628699, rat [Q8K585-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
3159
RGDi628699, Hmga1

Phylogenomic databases

eggNOGiENOG502S5JW, Eukaryota
GeneTreeiENSGT00730000111329
HOGENOMiCLU_138888_0_0_1
InParanoidiQ8K585
KOiK09282
OMAiFCEEASG
OrthoDBi1603551at2759
PhylomeDBiQ8K585
TreeFamiTF351623

Enzyme and pathway databases

ReactomeiR-RNO-2559584, Formation of Senescence-Associated Heterochromatin Foci (SAHF)

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q8K585

Gene expression databases

BgeeiENSRNOG00000000488, Expressed in thymus and 21 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR017956, AT_hook_DNA-bd_motif
IPR000116, HMGA
IPR031079, HMGA1_mammal
IPR000637, HMGI/Y_DNA-bd_CS
PANTHERiPTHR23341:SF6, PTHR23341:SF6, 1 hit
PfamiView protein in Pfam
PF02178, AT_hook, 3 hits
PRINTSiPR00929, ATHOOK
PR00930, HIGHMOBLTYIY
SMARTiView protein in SMART
SM00384, AT_hook, 3 hits
PROSITEiView protein in PROSITE
PS00354, HMGI_Y, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiHMGA1_RAT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8K585
Secondary accession number(s): Q8K1F5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 6, 2005
Last sequence update: January 23, 2007
Last modified: August 12, 2020
This is version 141 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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