Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 100 (05 Jun 2019)
Sequence version 2 (05 Dec 2018)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein

Usherin

Gene

Ush2a

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in hearing and vision as member of the USH2 complex. In the inner ear, required for the hair bundle ankle formation, which connects growing stereocilia in developing cochlear hair cells. In retina photoreceptors, the USH2 complex is required for the maintenance of periciliary membrane complex that seems to play a role in regulating intracellular protein transport.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processHearing, Sensory transduction, Vision

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Usherin
Alternative name(s):
Usher syndrome type IIa protein homolog
Usher syndrome type-2A protein homolog
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Ush2a
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

Organism-specific databases

Rat genome database

More...
RGDi
628777 Ush2a

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell membrane, Cell projection, Membrane, Secreted

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 33Sequence analysisAdd BLAST33
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000022980634 – 5125UsherinAdd BLAST5092

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi120N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi229N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi257N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi273N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi414N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi447N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi468N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi514 ↔ 523PROSITE-ProRule annotation
Disulfide bondi516 ↔ 532PROSITE-ProRule annotation
Disulfide bondi534 ↔ 545PROSITE-ProRule annotation
Disulfide bondi548 ↔ 568PROSITE-ProRule annotation
Disulfide bondi571 ↔ 580PROSITE-ProRule annotation
Disulfide bondi573 ↔ 601PROSITE-ProRule annotation
Disulfide bondi604 ↔ 613PROSITE-ProRule annotation
Disulfide bondi616 ↔ 634PROSITE-ProRule annotation
Disulfide bondi637 ↔ 651PROSITE-ProRule annotation
Disulfide bondi639 ↔ 658PROSITE-ProRule annotation
Glycosylationi646N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi660 ↔ 669PROSITE-ProRule annotation
Disulfide bondi672 ↔ 687PROSITE-ProRule annotation
Disulfide bondi690 ↔ 704PROSITE-ProRule annotation
Disulfide bondi692 ↔ 711PROSITE-ProRule annotation
Disulfide bondi713 ↔ 722PROSITE-ProRule annotation
Disulfide bondi725 ↔ 740PROSITE-ProRule annotation
Disulfide bondi743 ↔ 755PROSITE-ProRule annotation
Disulfide bondi745 ↔ 762PROSITE-ProRule annotation
Disulfide bondi764 ↔ 773PROSITE-ProRule annotation
Disulfide bondi776 ↔ 788PROSITE-ProRule annotation
Disulfide bondi791 ↔ 804PROSITE-ProRule annotation
Disulfide bondi793 ↔ 811PROSITE-ProRule annotation
Disulfide bondi813 ↔ 822PROSITE-ProRule annotation
Disulfide bondi825 ↔ 840PROSITE-ProRule annotation
Glycosylationi835N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi843 ↔ 857PROSITE-ProRule annotation
Disulfide bondi845 ↔ 864PROSITE-ProRule annotation
Glycosylationi852N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi866 ↔ 875PROSITE-ProRule annotation
Disulfide bondi878 ↔ 893PROSITE-ProRule annotation
Glycosylationi884N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi896 ↔ 909PROSITE-ProRule annotation
Disulfide bondi898 ↔ 916PROSITE-ProRule annotation
Disulfide bondi918 ↔ 927PROSITE-ProRule annotation
Disulfide bondi930 ↔ 944PROSITE-ProRule annotation
Glycosylationi940N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi947 ↔ 959PROSITE-ProRule annotation
Disulfide bondi949 ↔ 966PROSITE-ProRule annotation
Disulfide bondi981 ↔ 995PROSITE-ProRule annotation
Disulfide bondi998 ↔ 1010PROSITE-ProRule annotation
Disulfide bondi1000 ↔ 1017PROSITE-ProRule annotation
Glycosylationi1007N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi1019 ↔ 1028PROSITE-ProRule annotation
Disulfide bondi1031 ↔ 1046PROSITE-ProRule annotation
Glycosylationi1067N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1149N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1170N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1221N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1304N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1381N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi1660 ↔ 1697PROSITE-ProRule annotation
Disulfide bondi1850 ↔ 1879PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8K3K1

PRoteomics IDEntifications database

More...
PRIDEi
Q8K3K1

PTM databases

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8K3K1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Present in the synaptic terminals of inner ear hair cells (at protein level). Predominantly expressed in the retina and cochlea. Weakly expressed in brain and kidney. Detectable from E17 in the neural epithelium, but not in the retinal pigment epithelium (RPE) of the developing retina. After birth, it is expressed at P7 and remains expressed during adulthood.2 Publications

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with collagen IV and fibronectin via its laminin EGF-like domains. Interaction with collagen may be required for stable integration into the basement membrane.

Interacts with NINL (By similarity).

Interacts with USH1C.

Interacts (via the cytoplasmic region) with PDZD7.

Component of USH2 complex, composed of ADGRV1, PDZD7, USH2A and WHRN.

Interacts with ADGRV1/MASS1 (via N-terminal PDZ domain).

Interacts (via the cytoplasmic region) with WHRN.

Interacts (via the cytoplasmic region) with VEZT and MYO7A (via MyTH4-FERM domains); the interaction associates VEZT with the USH2 complex at the stereocilia base (By similarity).

By similarity

GO - Molecular functioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q8K3K1, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10116.ENSRNOP00000004992

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini273 – 513Laminin N-terminalPROSITE-ProRule annotationAdd BLAST241
Domaini514 – 570Laminin EGF-like 1PROSITE-ProRule annotationAdd BLAST57
Domaini571 – 636Laminin EGF-like 2PROSITE-ProRule annotationAdd BLAST66
Domaini637 – 689Laminin EGF-like 3PROSITE-ProRule annotationAdd BLAST53
Domaini690 – 742Laminin EGF-like 4PROSITE-ProRule annotationAdd BLAST53
Domaini743 – 790Laminin EGF-like 5PROSITE-ProRule annotationAdd BLAST48
Domaini791 – 842Laminin EGF-like 6PROSITE-ProRule annotationAdd BLAST52
Domaini843 – 895Laminin EGF-like 7PROSITE-ProRule annotationAdd BLAST53
Domaini896 – 946Laminin EGF-like 8PROSITE-ProRule annotationAdd BLAST51
Domaini947 – 997Laminin EGF-like 9PROSITE-ProRule annotationAdd BLAST51
Domaini998 – 1048Laminin EGF-like 10PROSITE-ProRule annotationAdd BLAST51
Domaini1054 – 1142Fibronectin type-III 1PROSITE-ProRule annotationAdd BLAST89
Domaini1146 – 1240Fibronectin type-III 2PROSITE-ProRule annotationAdd BLAST95
Domaini1241 – 1356Fibronectin type-III 3PROSITE-ProRule annotationAdd BLAST116
Domaini1357 – 1461Fibronectin type-III 4PROSITE-ProRule annotationAdd BLAST105
Domaini1510 – 1697Laminin G-like 1PROSITE-ProRule annotationAdd BLAST188
Domaini1702 – 1879Laminin G-like 2PROSITE-ProRule annotationAdd BLAST178
Domaini1857 – 1943Fibronectin type-III 5PROSITE-ProRule annotationAdd BLAST87
Domaini1945 – 2042Fibronectin type-III 6PROSITE-ProRule annotationAdd BLAST98
Domaini2043 – 2132Fibronectin type-III 7PROSITE-ProRule annotationAdd BLAST90
Domaini2133 – 2230Fibronectin type-III 8PROSITE-ProRule annotationAdd BLAST98
Domaini2231 – 2318Fibronectin type-III 9PROSITE-ProRule annotationAdd BLAST88
Domaini2319 – 2421Fibronectin type-III 10PROSITE-ProRule annotationAdd BLAST103
Domaini2425 – 2519Fibronectin type-III 11PROSITE-ProRule annotationAdd BLAST95
Domaini2520 – 2613Fibronectin type-III 12PROSITE-ProRule annotationAdd BLAST94
Domaini2614 – 2709Fibronectin type-III 13PROSITE-ProRule annotationAdd BLAST96
Domaini2713 – 2806Fibronectin type-III 14PROSITE-ProRule annotationAdd BLAST94
Domaini2807 – 2910Fibronectin type-III 15PROSITE-ProRule annotationAdd BLAST104
Domaini2914 – 3005Fibronectin type-III 16PROSITE-ProRule annotationAdd BLAST92
Domaini3009 – 3099Fibronectin type-III 17PROSITE-ProRule annotationAdd BLAST91
Domaini3380 – 3485Fibronectin type-III 18PROSITE-ProRule annotationAdd BLAST106
Domaini3486 – 3577Fibronectin type-III 19PROSITE-ProRule annotationAdd BLAST92
Domaini3580 – 3670Fibronectin type-III 20PROSITE-ProRule annotationAdd BLAST91
Domaini3672 – 3762Fibronectin type-III 21PROSITE-ProRule annotationAdd BLAST91
Domaini3765 – 3852Fibronectin type-III 22PROSITE-ProRule annotationAdd BLAST88
Domaini3853 – 3950Fibronectin type-III 23PROSITE-ProRule annotationAdd BLAST98
Domaini3951 – 4054Fibronectin type-III 24PROSITE-ProRule annotationAdd BLAST104
Domaini4055 – 4143Fibronectin type-III 25PROSITE-ProRule annotationAdd BLAST89
Domaini4144 – 4251Fibronectin type-III 26PROSITE-ProRule annotationAdd BLAST108
Domaini4252 – 4344Fibronectin type-III 27PROSITE-ProRule annotationAdd BLAST93
Domaini4345 – 4432Fibronectin type-III 28PROSITE-ProRule annotationAdd BLAST88
Domaini4433 – 4517Fibronectin type-III 29PROSITE-ProRule annotationAdd BLAST85
Domaini4518 – 4620Fibronectin type-III 30PROSITE-ProRule annotationAdd BLAST103
Domaini4625 – 4720Fibronectin type-III 31PROSITE-ProRule annotationAdd BLAST96
Domaini4721 – 4813Fibronectin type-III 32PROSITE-ProRule annotationAdd BLAST93
Domaini4814 – 4916Fibronectin type-III 33PROSITE-ProRule annotationAdd BLAST103

Keywords - Domaini

Laminin EGF-like domain, Repeat, Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1836 Eukaryota
ENOG410XRDC LUCA

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8K3K1

Identification of Orthologs from Complete Genome Data

More...
OMAi
CTKYACV

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8K3K1

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00063 FN3, 32 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.120.1490, 1 hit
2.60.40.10, 33 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR013320 ConA-like_dom_sf
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR013783 Ig-like_fold
IPR006558 LamG-like
IPR002049 Laminin_EGF
IPR001791 Laminin_G
IPR008211 Laminin_N
IPR038684 Laminin_N_sf
IPR026915 USH2A

The PANTHER Classification System

More...
PANTHERi
PTHR10574:SF274 PTHR10574:SF274, 14 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00041 fn3, 12 hits
PF00053 Laminin_EGF, 9 hits
PF00054 Laminin_G_1, 2 hits
PF00055 Laminin_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00180 EGF_Lam, 10 hits
SM00060 FN3, 34 hits
SM00282 LamG, 2 hits
SM00560 LamGL, 1 hit
SM00136 LamNT, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49265 SSF49265, 21 hits
SSF49899 SSF49899, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00022 EGF_1, 6 hits
PS01248 EGF_LAM_1, 6 hits
PS50027 EGF_LAM_2, 10 hits
PS50853 FN3, 33 hits
PS50025 LAM_G_DOMAIN, 2 hits
PS51117 LAMININ_NTER, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Note: A number of isoforms are produced.
Isoform 1 (identifier: Q8K3K1-2) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MYYLALSSGF LGQAIKTSIL AYLASVLLAA SQGVFPRLEN VGAFKKVSIV
60 70 80 90 100
PSHATCGYPG PSTFCRSAVA AEHAQLCAER LCIQDCPYRS ASPPYTALLE
110 120 130 140 150
GLRSCIPADH GDLHPYSRSN STSFIFGSHK NCPSLQAPRL AAEFTLAVWL
160 170 180 190 200
KPERGSTMCV LEKTADGQIV FKVTISERET MFYYRTVNGL QPPIKVMTPG
210 220 230 240 250
RILMKKWIHH TVQVHETEVS SFVDGLEENS TAFDTRTLRD SIMDSVPSTV
260 270 280 290 300
LIGQSLNGSE LFVGRMQDFR LYNVSLTNRE ILELFSGDLP HLHIQSHCRC
310 320 330 340 350
PGSHPRVHPS VQQYCIPNGV EDTLQHRVSR LNPEAHPLSF INDDDVATSW
360 370 380 390 400
ISHVFTDITQ LNQGVAISID LENGQYQVFQ ITIRFSSPQP VAMRIQRKKA
410 420 430 440 450
DKSLWEDWQY FARNCSVWGM KNNGDLENPN SVNCLQFPEF IPFSHGNVTF
460 470 480 490 500
DLLTSGQKHR PGDYDFYNSS LLQEFMTATQ IRLYFRGLFY PAWHTVDSRH
510 520 530 540 550
RYYAVDEITI IGRCQCHGHA ETCDRTRRPY RCLCSPHSFT EGPQCGRCSP
560 570 580 590 600
LYNDKPFRSG NKVHAFNCKP CQCHGHASSC HYDASMDPFP LEYNRGGGGV
610 620 630 640 650
CDDCQHHTTG RNCESCQDYF YRPIGADPAD PEVCKHCDCN RDGTRNGSLL
660 670 680 690 700
CDLVGDQCDC KRRVSGRRCF RCHIGFYGLQ ALDPDCCRPC DCNPSGTVDG
710 720 730 740 750
DITCHHNSGQ CSCKANVIGL RCDRCSFGFK FLRSLNADGC EPCHCNLHGS
760 770 780 790 800
VNQLCDPLSG QCVCKKEAKG LRCDVCRENF YGLPWSACEV CDCNRAGTQA
810 820 830 840 850
GTVCDAETGQ CVCKPSVGGR RCSECKEGYF NLRQNDSHLC LPCNCEKTGT
860 870 880 890 900
VNGSLLCDKS TGQCPCKLGV TGLRCHQCKP HRFNLTMDNP QGCQACDCDS
910 920 930 940 950
LGTLLGSMCD PVSGQCLCLP HRQERRCVQC QPGCYSSPSN ATGCLPCLCH
960 970 980 990 1000
TVATKNCICN SVTGHCYCPD PSTTGLSWHQ CQDRYFRFDP LTGRCRPCHC
1010 1020 1030 1040 1050
HVAGASNGTC DAVTGQCFCK EFVTGSKCDT CVPGASHLDV NNLLACSKTP
1060 1070 1080 1090 1100
SQQPPPRGRV QSSSAINLSW SPPDFPNAHW LTYTLFRDDS EIYTTDDQHP
1110 1120 1130 1140 1150
YYTQYFLDTS LSPHTAYSYY IETSNVHSST RSIPVIYKTK PEGSEGHLNL
1160 1170 1180 1190 1200
THIIPVASDS ITLVWTGLSN HSGPIEKYVL SCTPVDHTEP CVSYEGPETS
1210 1220 1230 1240 1250
ATIRNLVPFT QYCFSVQGCT NGSCLYSSPI TVTTAQAPPQ RQEPPTVWKI
1260 1270 1280 1290 1300
SPTELKVEWS RPVDSNGVII RYELYMKRWP STEESLVFES HGWFHSHPAS
1310 1320 1330 1340 1350
PSANQSENVL QDPQVSTVLS GLDPHTEYAF RVLAVNMAGS VSSAWASERT
1360 1370 1380 1390 1400
GESAPVFMAA PSVSPLSPYS LSVSWEKPAE NFTRGEIIGY KISMVSERSP
1410 1420 1430 1440 1450
QRDVPVMCSK LVHFAESQDQ SYIVQRLKPY RTYSFTVSLC ASVGCVTSAL
1460 1470 1480 1490 1500
GEGQTLAAAP AQLRSPMVTG VTSTTVHIRW LPPAEVNGPP PLYRLERRES
1510 1520 1530 1540 1550
FLPAATAART KGTRFMGDGY CRFPRTAHPD FIGIKASFWT RVPEGLILLA
1560 1570 1580 1590 1600
LHPDNQEEYF ALQLKSGRPY FLYNPQGSLV EVTTADDHSQ QYSDGQWHEI
1610 1620 1630 1640 1650
TAIRHQSFGQ ITLDEQYTDS SASLNGSSVT GGYTRLFVGG LPQGHTILQK
1660 1670 1680 1690 1700
RPVRRGFVGC LKDVSILKGS SPSGTWLPLD WQSSEEQVNV HHSWEGCPTD
1710 1720 1730 1740 1750
LEEGVQFLGA GFLELRSDTF HAAKDFEISL KFQTDQLNGL LLFIHNTEGL
1760 1770 1780 1790 1800
DFLAMELKSG LLSFQLNSSR ILTRVEVRLG RTHCDGKWNR VTIRREGSMV
1810 1820 1830 1840 1850
SVGVNELTKS TSRAGDQPPL LTSPVYLGGI PQELQASYRH LTLEQGFRGC
1860 1870 1880 1890 1900
VKEVAFTRGA VVNLASVSSR AVRVNQDGCL SSDSTVNCGG NDSILVYRGS
1910 1920 1930 1940 1950
RQSVYESGLQ PFTEYLYRVT ASHKGGSVSS DWSRGRTLGS APHSVPTPSR
1960 1970 1980 1990 2000
AQSINGYSVE VAWNEPAMVK GVLEKYILKA YSEDSAQPHM PSASTEFNNT
2010 2020 2030 2040 2050
DIRTGILTGL HPFHSYAVTL TACSRAGCTE SSRALSISTP QEAPQEVQAP
2060 2070 2080 2090 2100
VAEALPNSLS FFWSPPRQAN GIITQYSLYM DGRLVYTGKG QNYTVTDLRV
2110 2120 2130 2140 2150
FTAYEITVGA CTRAGCTNSS RVILHTAQLP PERVDPPVLA ILDSRTVHIQ
2160 2170 2180 2190 2200
WKQPRQLNGI LERYILYTLN PTHNSTVWDV VYNSTENLQT HLLYHLSPGC
2210 2220 2230 2240 2250
LYLIKLGACT GGGCTTSEPS QALMDETVPE GVPAPRAHSH SPDSFNISWT
2260 2270 2280 2290 2300
EPGHPNGVIT TYELYLDGTL IHNSSELSCH AYGFDPGSLH TFQVQACTAK
2310 2320 2330 2340 2350
GCALGPLVEN RTLEAPPEGT VNLFVKPEGS REAAVRWDAP PHPNGRLTYS
2360 2370 2380 2390 2400
VLITGNFYAD QAGDNYTLLS STKTVHSSKG DRLWVLVDRL VPCSNYTVQV
2410 2420 2430 2440 2450
NASNSQGSVL SDRVSVEMPP GAPDGLLSPR LAAATPTSLQ VVWSTPARNN
2460 2470 2480 2490 2500
APGSPRYQLQ MRPDPSTRGL LELFPIPSAL LSYEVTGLQP FTVYEFRLVA
2510 2520 2530 2540 2550
TNGFGSAYSD WTPLMTTEDK PGPMDAPVLN VKAGMMSVAW RKPTECNGAI
2560 2570 2580 2590 2600
THYNIYQHGR LYLTVSGGVT NCTVVHLRPH TAYQFQIEAC SSKGCSMSPA
2610 2620 2630 2640 2650
SETVWTLPGT PEGIPGPELL PYTPTKIIVS WQPPTHLDGL VENITIERRV
2660 2670 2680 2690 2700
KEQEEVRSLV ILPRSQAVRF IDNDPALRPW THYEYRVLGS TLNGGTNSSA
2710 2720 2730 2740 2750
WVEVTTRPSR PSGVQPPTVH VLGPDAVEVT WKAPLIRNGD IVSYEIRMPD
2760 2770 2780 2790 2800
PLIEITNVTS FVLSHLVKHL IPFTNYSVSI VACSGGHGYL GGCTESLPTF
2810 2820 2830 2840 2850
ATTHPALPQE LTPLSISLLG QSYVGISWQP PSKPNGPNLR YELLRRKIQQ
2860 2870 2880 2890 2900
PLASNPPEDL NLWHNIYSGT RRFYEDKGLS RFTTYEYKLF VHNSLGFTPS
2910 2920 2930 2940 2950
QEVTVTTLAG SPERGATVTA SILNHTAIDV RWKRPTFQDL QGDVEYYTLF
2960 2970 2980 2990 3000
WSSGTSVESL KIFPDVDFHV IGHLAPNVEY QVFLLVFNGV HAINSTVVRV
3010 3020 3030 3040 3050
TTWEEEPRGM RPPEVVIINS TAVRVIWTSP SNPNAVITES SVYANNELHK
3060 3070 3080 3090 3100
AGAGAPGSFT LEDLSPFTIY DIQVEVCTKD ACVKSSGTQV STAEDTPSGI
3110 3120 3130 3140 3150
SIPIIRDITS RSLQIDWTAP GNPNGIILGY DVLRKTWRLC SETQKLTDKP
3160 3170 3180 3190 3200
RDELCKAVKC QYPGNVCGHT CYSPGTKVCC DGLLYDPQPG YSCCEEKYIA
3210 3220 3230 3240 3250
LLPNSTGVCC GGRQREAQPD HQCCSGHYIR ILPGEICCPD ERHNRVSVGF
3260 3270 3280 3290 3300
GDACCGTMPY ATSGSQVCCA GKLQDGYRRQ CCGGEMVSQD FKCCGGGEEG
3310 3320 3330 3340 3350
MVYSSLPGML CCGQDYVNMS DTICCSASSG DSKAHVRGSD PMPVRCCHTE
3360 3370 3380 3390 3400
LIPESQQCCD GVGYNPVKYV CSDEISAGMA TEETRVCATV CPATMRATAH
3410 3420 3430 3440 3450
CGQCDFNATT HICTVSRGPL NPIGKETAEG LCSTAEEIVH SGDENTRSFI
3460 3470 3480 3490 3500
DTDLEPSTVY EYRVSVWNSY GRGFSQSVRA STREDVPQGV TAPRWARTGN
3510 3520 3530 3540 3550
HEDVIFLTWK EPTQSNGPIT HYILLRDGRE RFQGAALSFT DTQGIQPLQE
3560 3570 3580 3590 3600
YSYQLKACTA AGCADSCKVV ATATRGVLES VPPPNITAQS PETLHLSWSV
3610 3620 3630 3640 3650
PEKRNDAIKE YQLWLDGKGL IYTDTNDRRQ HTVTGLQPHT NYSFTLSACT
3660 3670 3680 3690 3700
SVGCTSSEPS VGQTLQAAPQ GVWVTPRHII INSTTVELYW NPPERPNGVI
3710 3720 3730 3740 3750
SQYRLRRNGS LLLVGGRDDQ SFTDKNLEPN SRYIYTLEAR TGGGSSLSEE
3760 3770 3780 3790 3800
YLVQMPMWTP EDVHPPCNVT VLGSDSIFVA WPAPGILLPK IPVEYSILLS
3810 3820 3830 3840 3850
GGNMMLLTFS VGLRQSAYLK NLAPFTQYEI RIQACQEGCG VSPGTHVRTL
3860 3870 3880 3890 3900
EAAPVGLMPP LLKALGSHCI EVKWTPPTRP NGIITSYVIH RRPADTEEES
3910 3920 3930 3940 3950
LLFVWSEGAL EFTDDTDTLR PFTLYEYRVR AWNSKGVVDS PWSSVQTLEA
3960 3970 3980 3990 4000
PPQDLPAPWV QVTSAHSVLL NWTEPEAPNG LISQYHVIYQ ERPDEAAPGS
4010 4020 4030 4040 4050
STVHAFTVKG SSRQAHLFGL EPFTTYHIGV AAVNRAGKVS SPWTLIKTLE
4060 4070 4080 4090 4100
SAPSGLMNFT AEQREGGRAL LLQWSEPVRT NGVIKAYNVF SDGLPEYSGL
4110 4120 4130 4140 4150
GRQFLFRRLA PFTLYILTLE ACTAAGCAHS VPQTLWTEEA PPDSQMAPTI
4160 4170 4180 4190 4200
QSVEPTSVRL HWSQPANPNG KIIRYEVIRR RLQGEDWGNR TVQADENTVF
4210 4220 4230 4240 4250
TEYNTEGNGW VCTDTGLQPW GLYSYRICTW NSAGHTCSSW SVVRTSQAPP
4260 4270 4280 4290 4300
DGLSPPEVSY VSTSPLQLLI SWFAPRHTNG VIQSYRLQRN GVFAAASFNS
4310 4320 4330 4340 4350
STFSYTDGQL LPFTTYSYAV LACTGGGCCT SEPTNITTPE ASPAGVSPPV
4360 4370 4380 4390 4400
LWAIGAHQIN VSWSPPSVPN GKIAKYLLHC DGEEHLAGQD LSLLLSNLRP
4410 4420 4430 4440 4450
FTQYNVSLVA CTKGGCTASR VASAWTMEAP PEDMDPPTLH VMGPESIEIT
4460 4470 4480 4490 4500
WAPPRNPHGQ IRSYELRRDG AIVYIGLETR YHDFILTPGV QYGYTVTATN
4510 4520 4530 4540 4550
SRGSVLSPLV KGQTSPSAPS GLQPPKLRAG EALELLVNWN PPVRTNGKIT
4560 4570 4580 4590 4600
NYTLFIRELL EGEIRTMCIN TTHSSFGTRS LAVKHLKPFH RYEVRVQACT
4610 4620 4630 4640 4650
ALGCTSSEWT PTQTSEIPPL LQPAPHLEVQ TAAGGFQPIV AVWWAGPLQP
4660 4670 4680 4690 4700
HGKIVRFELY RRQTASWPGT SSPLLIYNGS LSSFTDRELL PFTEYEYQVW
4710 4720 4730 4740 4750
AVNSAGKVAS NWTWCRTGPA PPEGLKAPTF HTVSSTQAVV NISAPSKPNG
4760 4770 4780 4790 4800
NISLFRVFSN SSGTHVMLSE GMATQQTLHD LRPFTTYAIG VEACTCFNCC
4810 4820 4830 4840 4850
SRGPTAELRT HPAPPSGLSP PQVQTLGSRM ASFQWAPPQL PNGVIHSYEL
4860 4870 4880 4890 4900
QLHRACPPDS APHCPPSPTE RKYWGPGHRA SLAGLQPNTA YGVQVVAHNE
4910 4920 4930 4940 4950
AGSTASGWTS FRTKKEMPQY QALFSVDSNA STVWVDWSGT FVLNGQLKEY
4960 4970 4980 4990 5000
VVTDGGRRVY SGLDTTLYIP RTVDKTFFFQ VTCTTDIGSV KTPLVQYDAT
5010 5020 5030 5040 5050
TGFGLVLTTP GGKKGAGTKS TEFYTDTRLP RSGTPVSIRS SQSVSVLRIP
5060 5070 5080 5090 5100
SQSQLSHAYS QGSLHRSVSQ LMDSPDKKAL TEDSLWETIM GHSSGLCVDE
5110 5120
EELMNAIKGF SSVTKEHTAF TDTHL
Length:5,125
Mass (Da):562,986
Last modified:December 5, 2018 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9CC58BA0D18511D0
GO
Isoform 2 (identifier: Q8K3K1-1) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1457-5125: AAAPAQLRSP...EHTAFTDTHL → TAGKNVLTNT...YLESFKQNQH

Show »
Length:1,512
Mass (Da):167,592
Checksum:iE37D79F5D00044C1
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti52S → T in AAL78289 (PubMed:12160733).Curated1
Sequence conflicti210 – 211HT → LS in AAL78289 (PubMed:12160733).Curated2
Sequence conflicti221S → F in AAL78289 (PubMed:12160733).Curated1
Sequence conflicti243 – 246MDSV → TDSA in AAL78289 (PubMed:12160733).Curated4
Sequence conflicti439E → D in AAL78289 (PubMed:12160733).Curated1
Sequence conflicti531R → Q in AAL78289 (PubMed:12160733).Curated1
Sequence conflicti656D → G in AAL78289 (PubMed:12160733).Curated1
Sequence conflicti686C → G in AAL78289 (PubMed:12160733).Curated1
Sequence conflicti879K → E in AAL78289 (PubMed:12160733).Curated1
Sequence conflicti887 – 890MDNP → VDNL in AAL78289 (PubMed:12160733).Curated4
Sequence conflicti897D → E in AAL78289 (PubMed:12160733).Curated1
Sequence conflicti905 – 908LGSM → PGST in AAL78289 (PubMed:12160733).Curated4
Sequence conflicti924 – 939ERRCV…YSSPS → GRRCERCQPGFYSSPG in AAL78289 (PubMed:12160733).CuratedAdd BLAST16
Sequence conflicti948 – 957LCHTVATKNC → SCHTAGAVSH in AAL78289 (PubMed:12160733).Curated10
Sequence conflicti965 – 969HCYCP → QCSCR in AAL78289 (PubMed:12160733).Curated5
Sequence conflicti976 – 978LSW → QSC in AAL78289 (PubMed:12160733).Curated3
Sequence conflicti984 – 996RYFRF…TGRCR → HYFGFDPRTGRCQ in AAL78289 (PubMed:12160733).CuratedAdd BLAST13
Sequence conflicti1002 – 1012VAGASNGTCDA → LEGALNETCDV in AAL78289 (PubMed:12160733).CuratedAdd BLAST11
Sequence conflicti1030T → I in AAL78289 (PubMed:12160733).Curated1
Sequence conflicti1044 – 1045LA → FG in AAL78289 (PubMed:12160733).Curated2
Sequence conflicti1441A → Y in AAL78289 (PubMed:12160733).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0599451457 – 5125AAAPA…TDTHL → TAGKNVLTNTKKCTHVGNQY YRSAVLWASYMSSLFTAPSS DILDVVYLESFKQNQH in isoform 2. Add BLAST3669

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY077844 mRNA Translation: AAL78289.1
AABR07022087 Genomic DNA No translation available.
AABR07022096 Genomic DNA No translation available.
AABR07022088 Genomic DNA No translation available.
AABR07022089 Genomic DNA No translation available.
AABR07022090 Genomic DNA No translation available.
AABR07022091 Genomic DNA No translation available.
AABR07022092 Genomic DNA No translation available.
AABR07022094 Genomic DNA No translation available.
AABR07022093 Genomic DNA No translation available.
AABR07022095 Genomic DNA No translation available.

Genome annotation databases

UCSC genome browser

More...
UCSCi
RGD:628777 rat [Q8K3K1-2]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY077844 mRNA Translation: AAL78289.1
AABR07022087 Genomic DNA No translation available.
AABR07022096 Genomic DNA No translation available.
AABR07022088 Genomic DNA No translation available.
AABR07022089 Genomic DNA No translation available.
AABR07022090 Genomic DNA No translation available.
AABR07022091 Genomic DNA No translation available.
AABR07022092 Genomic DNA No translation available.
AABR07022094 Genomic DNA No translation available.
AABR07022093 Genomic DNA No translation available.
AABR07022095 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

IntActiQ8K3K1, 1 interactor
STRINGi10116.ENSRNOP00000004992

PTM databases

PhosphoSitePlusiQ8K3K1

Proteomic databases

PaxDbiQ8K3K1
PRIDEiQ8K3K1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

UCSCiRGD:628777 rat [Q8K3K1-2]

Organism-specific databases

RGDi628777 Ush2a

Phylogenomic databases

eggNOGiKOG1836 Eukaryota
ENOG410XRDC LUCA
InParanoidiQ8K3K1
OMAiCTKYACV
PhylomeDBiQ8K3K1

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q8K3K1

Family and domain databases

CDDicd00063 FN3, 32 hits
Gene3Di2.60.120.1490, 1 hit
2.60.40.10, 33 hits
InterProiView protein in InterPro
IPR013320 ConA-like_dom_sf
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR013783 Ig-like_fold
IPR006558 LamG-like
IPR002049 Laminin_EGF
IPR001791 Laminin_G
IPR008211 Laminin_N
IPR038684 Laminin_N_sf
IPR026915 USH2A
PANTHERiPTHR10574:SF274 PTHR10574:SF274, 14 hits
PfamiView protein in Pfam
PF00041 fn3, 12 hits
PF00053 Laminin_EGF, 9 hits
PF00054 Laminin_G_1, 2 hits
PF00055 Laminin_N, 1 hit
SMARTiView protein in SMART
SM00180 EGF_Lam, 10 hits
SM00060 FN3, 34 hits
SM00282 LamG, 2 hits
SM00560 LamGL, 1 hit
SM00136 LamNT, 1 hit
SUPFAMiSSF49265 SSF49265, 21 hits
SSF49899 SSF49899, 3 hits
PROSITEiView protein in PROSITE
PS00022 EGF_1, 6 hits
PS01248 EGF_LAM_1, 6 hits
PS50027 EGF_LAM_2, 10 hits
PS50853 FN3, 33 hits
PS50025 LAM_G_DOMAIN, 2 hits
PS51117 LAMININ_NTER, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiUSH2A_RAT
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8K3K1
Secondary accession number(s): F1M2F9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: December 5, 2018
Last modified: June 5, 2019
This is version 100 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again