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Entry version 142 (13 Feb 2019)
Sequence version 2 (23 Apr 2003)
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Protein

Condensin complex subunit 1

Gene

Ncapd2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. May target the condensin complex to DNA via its C-terminal domain. May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation. Required for decatenation of non-centromeric ultrafine DNA bridges during anaphase. Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • chromatin binding Source: GO_Central
  • histone binding Source: MGI

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell cycle, Cell division, DNA condensation, Mitosis

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Condensin complex subunit 1
Alternative name(s):
Chromosome condensation-related SMC-associated protein 1
Chromosome-associated protein D2
Short name:
mCAP-D2
Non-SMC condensin I complex subunit D2
XCAP-D2 homolog
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Ncapd2
Synonyms:Capd2, Cnap1, Kiaa0159
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1915548 Ncapd2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Cytoplasm, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000950361 – 1392Condensin complex subunit 1Add BLAST1392

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei20PhosphoserineBy similarity1
Modified residuei575PhosphoserineBy similarity1
Modified residuei1300PhosphoserineCombined sources1
Modified residuei1305PhosphoserineBy similarity1
Modified residuei1320PhosphoserineCombined sources1
Modified residuei1323PhosphoserineCombined sources1
Modified residuei1329PhosphothreonineCombined sources1
Modified residuei1358PhosphoserineCombined sources1
Modified residuei1361PhosphoserineCombined sources1
Modified residuei1362PhosphoserineCombined sources1
Modified residuei1367PhosphoserineBy similarity1
Modified residuei1375Phosphothreonine; by CDK1By similarity1
Modified residuei1380Phosphothreonine; by CDK1By similarity1
Modified residuei1386PhosphoserineBy similarity1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Phosphorylated by CDK1. Its phosphorylation, as well as that of NCAPH and NCAPG subunits, activates the condensin complex and is required for chromosome condensation (By similarity).By similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8K2Z4

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8K2Z4

PeptideAtlas

More...
PeptideAtlasi
Q8K2Z4

PRoteomics IDEntifications database

More...
PRIDEi
Q8K2Z4

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8K2Z4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8K2Z4

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the condensin complex, which contains the SMC2 and SMC4 heterodimer, and three non SMC subunits that probably regulate the complex: NCAPH/BRRN1, NCAPD2/CAPD2 and NCAPG. Interacts with histones H1 and H3 (By similarity).By similarity

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
212791, 2 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-980 Condensin I complex

Protein interaction database and analysis system

More...
IntActi
Q8K2Z4, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000042260

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q8K2Z4

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8K2Z4

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 593Interaction with SMC2 and SMC4By similarityAdd BLAST593

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi1332 – 1353Bipartite nuclear localization signalBy similarityAdd BLAST22

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The C-terminal domain interacts with histones H1 and H3, and may be responsible for condensin complex targeting to mitotic chromosomes. This domain is independent from the bipartite nuclear localization signal, although they are contained within the same region (By similarity).By similarity

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CND1 (condensin subunit 1) family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0414 Eukaryota
COG5098 LUCA

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG038048

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8K2Z4

KEGG Orthology (KO)

More...
KOi
K06677

Database of Orthologous Groups

More...
OrthoDBi
166920at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8K2Z4

TreeFam database of animal gene trees

More...
TreeFami
TF105712

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR026971 CND1/NCAPD3
IPR032682 Cnd1_C
IPR007673 Condensin_cplx_su1
IPR024324 Condensin_cplx_su1_N

The PANTHER Classification System

More...
PANTHERi
PTHR14222 PTHR14222, 1 hit
PTHR14222:SF2 PTHR14222:SF2, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12717 Cnd1, 1 hit
PF12922 Cnd1_N, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF017127 Condensin_D2, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371 SSF48371, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8K2Z4-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSPHNFEFHL PLSPEELLKS GGVNQYVVRE VLPVKHLSSQ LRAFQSAFRA
60 70 80 90 100
QGPLAILEHF DTVYSILHHF RSIEPGLKED TLEFLKKVVS RHSQELSSIL
110 120 130 140 150
DDAALSGSDR SAHLNALKMN CYALIRLLES FENMTSQTSL IDLDIGGKGK
160 170 180 190 200
RARAKATLGF DWEEERQPVL QLLTQLLQLD IRHLWNHSAI EEEFVSLVTG
210 220 230 240 250
CCYRLLENPT ISHQKNRSTK EAIAHLLGVA LVRYNHMLSA TVKIIQMLQH
260 270 280 290 300
FEHLPPVLVT AVSLWATDYG MKSIVGEIVR EIGQKCPQEL SRDTAGAKGF
310 320 330 340 350
AAFLTELAER IPAVLMANMC ILLDHLDGEN YMMRNAVLAA IAEMVLQVLN
360 370 380 390 400
GDQLEESARE TRDQFLDILQ AHGHDVNSFV RSRVLQLFAR IVQQKALPLT
410 420 430 440 450
RFQAVVALAV GRLADKSVLV CKNAIQLLAS FLANNPFSCK LSDIDLAGPL
460 470 480 490 500
QKEIQKLQEM RAQRRSAAAT AALDPEEEWD AMLPELKSTL QQLLKLPQEE
510 520 530 540 550
GDHQIADAET AEEVKGRIRQ LLAKASYKQA IVLTREATSH FQESEPFSHT
560 570 580 590 600
EPEENSFLNL LGLIFKGPEA STQDSHGDTD PGLTGSKDSP SVPEPEGSQS
610 620 630 640 650
NDELVKQEML VQYLQDAYGF SQKITEAIGI ISKMMYENTT TVVQEVIEFF
660 670 680 690 700
VMVFQFGVPQ ALFGVRRMLP LIWSKEPGVR EAVLNAYRQL YLNPKGDSAR
710 720 730 740 750
AKAQTLIHNL SLLLVDASVG TIQCLEEILC EFVQKDEVKP AVIQLLWERA
760 770 780 790 800
TEKVPSSPLE RCSSVMLLGM MARGKPEIVG SNLDALVRVG LDEKSPQDYR
810 820 830 840 850
LAQQVCLAIA NISDRRKPSL GERHPPFRLP QEHRLFERLQ DMVTKGFAHP
860 870 880 890 900
DPLWIPFKEV AVTLTYQLAE SPDVLCAQML QGCAKQVLEK LEKNATEADP
910 920 930 940 950
KETAPRLPTF LLMNLLSLAG DVALQQLVHL EQAVSGELGR RRVLREEQEH
960 970 980 990 1000
RAKEPKEKTA SSETTMEEEL GLVGGATADD TEAELIRSIC EKELLDGNQV
1010 1020 1030 1040 1050
LAAFVPLLLK VCNNPGLYSN PELCAAASLA LGKFCMISAP FCDSQLRLLF
1060 1070 1080 1090 1100
TMLEKSSLPT VRSNLMVATG DLAIRFPNLV DPWTPHLYAR LRDPAQQVRK
1110 1120 1130 1140 1150
TAGLVMTHLI LKDMVKVKGQ VSEMAVLLID PVPQIAALAK NFFNELSHKG
1160 1170 1180 1190 1200
NAIYNLLPDI ISRLSDPEGG VEEEPFHTIM KQLLSYITKD KQTESLVEKL
1210 1220 1230 1240 1250
CQRFRTARTE RQYRDLAYCM SQLPLTERGL QKMLDNFECF GDKLLDESVF
1260 1270 1280 1290 1300
SAFLSIVGKL RRGAKPEGKA IIDEFEQKLR ACHTRGMDGI EEFETGQGGS
1310 1320 1330 1340 1350
QRALSAKKPS AVSRLQPLTS VDSDNDFVTP KPRRTKPGRP QTQQRKKSQR
1360 1370 1380 1390
KAKVVFLSDE SSEDELSAEM TEEETPKRTT PIRRASGRRH RS
Length:1,392
Mass (Da):155,665
Last modified:April 23, 2003 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i192E117CC7172A87
GO
Isoform 2 (identifier: Q8K2Z4-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1382-1392: IRRASGRRHRS → TLVEVLVVCGFNMEMAFALRSFS

Note: No experimental confirmation available.
Show »
Length:1,404
Mass (Da):156,878
Checksum:i717D40C6778889AF
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0R4J0H7A0A0R4J0H7_MOUSE
Condensin complex subunit 1
Ncapd2
1,392Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WNQ1A0A087WNQ1_MOUSE
Condensin complex subunit 1
Ncapd2
162Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WRK6A0A087WRK6_MOUSE
Condensin complex subunit 1
Ncapd2
94Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH06673 differs from that shown. Contaminating sequence.Curated
The sequence BAC97878 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence BC025460 differs from that shown. Reason: Erroneous termination at position 1245. Translated as Leu.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti574D → G in AAH26982 (PubMed:15489334).Curated1
Sequence conflicti1256I → V in AAH26982 (PubMed:15489334).Curated1
Sequence conflicti1256I → V in BAB31633 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0072461382 – 1392IRRASGRRHRS → TLVEVLVVCGFNMEMAFALR SFS in isoform 2. 1 PublicationAdd BLAST11

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK129068 mRNA Translation: BAC97878.1 Different initiation.
BC006673 mRNA Translation: AAH06673.1 Sequence problems.
BC008592 mRNA Translation: AAH08592.1
BC025460 mRNA No translation available.
BC026982 mRNA Translation: AAH26982.1
BC029133 mRNA Translation: AAH29133.1
AK011352 mRNA Translation: BAB27560.1
AK019259 mRNA Translation: BAB31633.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS39636.1 [Q8K2Z4-1]

NCBI Reference Sequences

More...
RefSeqi
NP_666283.1, NM_146171.1
XP_006506594.1, XM_006506531.3

UniGene gene-oriented nucleotide sequence clusters

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UniGenei
Mm.257590

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
68298

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:68298

UCSC genome browser

More...
UCSCi
uc009dtt.1 mouse [Q8K2Z4-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK129068 mRNA Translation: BAC97878.1 Different initiation.
BC006673 mRNA Translation: AAH06673.1 Sequence problems.
BC008592 mRNA Translation: AAH08592.1
BC025460 mRNA No translation available.
BC026982 mRNA Translation: AAH26982.1
BC029133 mRNA Translation: AAH29133.1
AK011352 mRNA Translation: BAB27560.1
AK019259 mRNA Translation: BAB31633.1
CCDSiCCDS39636.1 [Q8K2Z4-1]
RefSeqiNP_666283.1, NM_146171.1
XP_006506594.1, XM_006506531.3
UniGeneiMm.257590

3D structure databases

ProteinModelPortaliQ8K2Z4
SMRiQ8K2Z4
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi212791, 2 interactors
ComplexPortaliCPX-980 Condensin I complex
IntActiQ8K2Z4, 1 interactor
STRINGi10090.ENSMUSP00000042260

PTM databases

iPTMnetiQ8K2Z4
PhosphoSitePlusiQ8K2Z4

Proteomic databases

EPDiQ8K2Z4
PaxDbiQ8K2Z4
PeptideAtlasiQ8K2Z4
PRIDEiQ8K2Z4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi68298
KEGGimmu:68298
UCSCiuc009dtt.1 mouse [Q8K2Z4-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
9918
MGIiMGI:1915548 Ncapd2

Rodent Unidentified Gene-Encoded large proteins database

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Rougei
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Phylogenomic databases

eggNOGiKOG0414 Eukaryota
COG5098 LUCA
HOVERGENiHBG038048
InParanoidiQ8K2Z4
KOiK06677
OrthoDBi166920at2759
PhylomeDBiQ8K2Z4
TreeFamiTF105712

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Ncapd2 mouse

Protein Ontology

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PROi
PR:Q8K2Z4

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Family and domain databases

Gene3Di1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR026971 CND1/NCAPD3
IPR032682 Cnd1_C
IPR007673 Condensin_cplx_su1
IPR024324 Condensin_cplx_su1_N
PANTHERiPTHR14222 PTHR14222, 1 hit
PTHR14222:SF2 PTHR14222:SF2, 1 hit
PfamiView protein in Pfam
PF12717 Cnd1, 1 hit
PF12922 Cnd1_N, 1 hit
PIRSFiPIRSF017127 Condensin_D2, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCND1_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8K2Z4
Secondary accession number(s): Q6ZQI1
, Q8R0F2, Q8R3H0, Q922B7, Q923A3, Q9CS25, Q9CT32
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 23, 2003
Last sequence update: April 23, 2003
Last modified: February 13, 2019
This is version 142 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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