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Entry version 134 (05 Jun 2019)
Sequence version 1 (01 Oct 2002)
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Protein

Polycomb protein SCMH1

Gene

Scmh1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Associates with Polycomb group (PcG) multiprotein complexes; the complex class is required to maintain the transcriptionally repressive state of some genes.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein, Repressor
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-2559580 Oxidative Stress Induced Senescence
R-MMU-3899300 SUMOylation of transcription cofactors
R-MMU-4551638 SUMOylation of chromatin organization proteins
R-MMU-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
R-MMU-8943724 Regulation of PTEN gene transcription

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Polycomb protein SCMH1
Alternative name(s):
Sex comb on midleg homolog 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Scmh1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1352762 Scmh1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001143351 – 706Polycomb protein SCMH1Add BLAST706

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8K214

PeptideAtlas

More...
PeptideAtlasi
Q8K214

PRoteomics IDEntifications database

More...
PRIDEi
Q8K214

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8K214

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8K214

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Most abundant in testis. Moderate levels detected in heart, brain, lung, liver, skeletal muscle and kidney and lower levels in spleen.1 Publication

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Detected throughout embryogenesis. Expressed ubiquitously in 8.5 dpc embryos. At 10.5 dpc, strongly expressed in nervous system including hindbrain and spinal cord, and in the pharyngeal arches and visceral organs. By 14.5 dpc, strong expression is detected throughout the central nervous system, and in tongue, heart, midgut and urogenital regions.1 Publication

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

By retinoic acid in F9 and F19 embryonal carcinoma cell lines.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000000085 Expressed in 292 organ(s), highest expression level in ear vesicle

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8K214 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8K214 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Associates with a PRC1-like complex (By similarity).

Interacts with the SAM domain of PHC1 via its SAM domain in vitro.

By similarity1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
205936, 5 interactors

Database of interacting proteins

More...
DIPi
DIP-32567N

Protein interaction database and analysis system

More...
IntActi
Q8K214, 5 interactors

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000101908

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8K214

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati28 – 126MBT 1Add BLAST99
Repeati134 – 235MBT 2Add BLAST102
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini597 – 662SAMPROSITE-ProRule annotationAdd BLAST66

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SCM family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IMEZ Eukaryota
ENOG410XPKI LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000157999

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000236280

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8K214

KEGG Orthology (KO)

More...
KOi
K11461

Identification of Orthologs from Complete Genome Data

More...
OMAi
APAHCFK

Database of Orthologous Groups

More...
OrthoDBi
229086at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8K214

TreeFam database of animal gene trees

More...
TreeFami
TF106488

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.150.50, 1 hit
1.20.1380.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR004092 Mbt
IPR001660 SAM
IPR013761 SAM/pointed_sf
IPR033763 SCML2_RBR
IPR021987 SLED
IPR038348 SLED_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02820 MBT, 2 hits
PF17208 RBR, 1 hit
PF00536 SAM_1, 1 hit
PF12140 SLED, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00561 MBT, 2 hits
SM00454 SAM, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47769 SSF47769, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51079 MBT, 2 hits
PS50105 SAM_DOMAIN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1Curated (identifier: Q8K214-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MLVCYSVLAC ESLWDLPCSI MGSPLGHFTW DKYLKETCSV PAPVHCFKQS
60 70 80 90 100
YTPPSNEFKI SMKLEAQDPR NTTSTCIATV VGLTGARLRL RLDGSDNKND
110 120 130 140 150
FWRLVDSSEI QPIGNCEKNG GMLQPPLGFR LNASSWPMFL LKTLNGAEMA
160 170 180 190 200
PIKIFHKEPP SPSHNFFKMG MKLEAVDRKN PHFICPATIG EVRGAEVLVT
210 220 230 240 250
FDGWRGAFDY WCRFDSRDIF PVGWCSLTGD NLQPPGTKVV IPKNPSPSSD
260 270 280 290 300
VSTEKPSIHS TKTVLEHQPG QRGRKPGKKR GRTPKILIPH PTSTPSKSAE
310 320 330 340 350
PLKFPKKRGP KPGSKRKPRT LLSPPPTSPT TSTPEPDTST VPQDAATVPS
360 370 380 390 400
SAMQAPTVCI YLNKSGSTGP HLDKKKIQQL PDHFGPARAS VVLQQAVQAC
410 420 430 440 450
IDCAYHQKTV FSFLKQGHGG EVISAVFDRE QHTLNLPAVN SITYVLRFLE
460 470 480 490 500
KLCHNLRSDN LFGNQPFTQT HLSLTATEYN HNHDRYLPGE TFVLGNSLAR
510 520 530 540 550
SLETHSDLMD SALKPANLVS TSQNLRTPGY RPLLPSCGLP LSTVSAVRRL
560 570 580 590 600
CSKGVLKGKK ERRDVESFWK LNHSPGSDRH LESRDPPRLS GRDPSSWTVE
610 620 630 640 650
DVMQFVREAD PQLGSHADLF RKHEIDGKAL LLLRSDMMMK YMGLKLGPAL
660 670 680 690 700
KLSFHIDRLK QVFWKRETIL WSREGLSREV WPISEDTALG HFFSGMDKVF

GSLSKR
Note: No experimental confirmation available.Curated
Length:706
Mass (Da):78,669
Last modified:October 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iCC7531B46A439E39
GO
Isoform 21 Publication (identifier: Q8K214-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     662-664: VFW → GKF
     665-706: Missing.

Show »
Length:664
Mass (Da):73,733
Checksum:i642EDBAF598D9179
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F6UK33F6UK33_MOUSE
Polycomb protein SCMH1
Scmh1
177Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B1AS49B1AS49_MOUSE
Polycomb protein SCMH1
Scmh1
28Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_051680662 – 664VFW → GKF in isoform 2. 1 Publication3
Alternative sequenceiVSP_051681665 – 706Missing in isoform 2. 1 PublicationAdd BLAST42

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB030906 mRNA Translation: BAA90554.1
AL611924 Genomic DNA No translation available.
BC034667 mRNA Translation: AAH34667.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS18589.1 [Q8K214-2]
CCDS51292.1 [Q8K214-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001153102.1, NM_001159630.1 [Q8K214-1]
NP_038911.1, NM_013883.2 [Q8K214-2]
XP_011238853.1, XM_011240551.1
XP_017175741.1, XM_017320252.1 [Q8K214-2]
XP_017175742.1, XM_017320253.1 [Q8K214-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000000087; ENSMUSP00000000087; ENSMUSG00000000085 [Q8K214-2]
ENSMUST00000064991; ENSMUSP00000069813; ENSMUSG00000000085 [Q8K214-1]
ENSMUST00000106298; ENSMUSP00000101905; ENSMUSG00000000085 [Q8K214-2]
ENSMUST00000106301; ENSMUSP00000101908; ENSMUSG00000000085 [Q8K214-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
29871

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:29871

UCSC genome browser

More...
UCSCi
uc008und.2 mouse [Q8K214-2]
uc008une.2 mouse [Q8K214-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB030906 mRNA Translation: BAA90554.1
AL611924 Genomic DNA No translation available.
BC034667 mRNA Translation: AAH34667.1
CCDSiCCDS18589.1 [Q8K214-2]
CCDS51292.1 [Q8K214-1]
RefSeqiNP_001153102.1, NM_001159630.1 [Q8K214-1]
NP_038911.1, NM_013883.2 [Q8K214-2]
XP_011238853.1, XM_011240551.1
XP_017175741.1, XM_017320252.1 [Q8K214-2]
XP_017175742.1, XM_017320253.1 [Q8K214-2]

3D structure databases

SMRiQ8K214
ModBaseiSearch...

Protein-protein interaction databases

BioGridi205936, 5 interactors
DIPiDIP-32567N
IntActiQ8K214, 5 interactors
STRINGi10090.ENSMUSP00000101908

PTM databases

iPTMnetiQ8K214
PhosphoSitePlusiQ8K214

Proteomic databases

PaxDbiQ8K214
PeptideAtlasiQ8K214
PRIDEiQ8K214

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000000087; ENSMUSP00000000087; ENSMUSG00000000085 [Q8K214-2]
ENSMUST00000064991; ENSMUSP00000069813; ENSMUSG00000000085 [Q8K214-1]
ENSMUST00000106298; ENSMUSP00000101905; ENSMUSG00000000085 [Q8K214-2]
ENSMUST00000106301; ENSMUSP00000101908; ENSMUSG00000000085 [Q8K214-1]
GeneIDi29871
KEGGimmu:29871
UCSCiuc008und.2 mouse [Q8K214-2]
uc008une.2 mouse [Q8K214-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
22955
MGIiMGI:1352762 Scmh1

Phylogenomic databases

eggNOGiENOG410IMEZ Eukaryota
ENOG410XPKI LUCA
GeneTreeiENSGT00940000157999
HOGENOMiHOG000236280
InParanoidiQ8K214
KOiK11461
OMAiAPAHCFK
OrthoDBi229086at2759
PhylomeDBiQ8K214
TreeFamiTF106488

Enzyme and pathway databases

ReactomeiR-MMU-2559580 Oxidative Stress Induced Senescence
R-MMU-3899300 SUMOylation of transcription cofactors
R-MMU-4551638 SUMOylation of chromatin organization proteins
R-MMU-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
R-MMU-8943724 Regulation of PTEN gene transcription

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Scmh1 mouse

Protein Ontology

More...
PROi
PR:Q8K214

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000000085 Expressed in 292 organ(s), highest expression level in ear vesicle
ExpressionAtlasiQ8K214 baseline and differential
GenevisibleiQ8K214 MM

Family and domain databases

Gene3Di1.10.150.50, 1 hit
1.20.1380.20, 1 hit
InterProiView protein in InterPro
IPR004092 Mbt
IPR001660 SAM
IPR013761 SAM/pointed_sf
IPR033763 SCML2_RBR
IPR021987 SLED
IPR038348 SLED_sf
PfamiView protein in Pfam
PF02820 MBT, 2 hits
PF17208 RBR, 1 hit
PF00536 SAM_1, 1 hit
PF12140 SLED, 1 hit
SMARTiView protein in SMART
SM00561 MBT, 2 hits
SM00454 SAM, 1 hit
SUPFAMiSSF47769 SSF47769, 1 hit
PROSITEiView protein in PROSITE
PS51079 MBT, 2 hits
PS50105 SAM_DOMAIN, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSCMH1_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8K214
Secondary accession number(s): B1AS51, Q9JME0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 1, 2005
Last sequence update: October 1, 2002
Last modified: June 5, 2019
This is version 134 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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