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Entry version 132 (13 Nov 2019)
Sequence version 1 (01 Oct 2002)
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Protein

WD repeat-containing protein 11

Gene

Wdr11

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in the Hedgehog (Hh) signaling pathway, is essential for normal ciliogenesis (PubMed:29263200). Regulates the proteolytic processing of GLI3 and cooperates with the transcription factor EMX1 in the induction of downstream Hh pathway gene expression and gonadotropin-releasing hormone production (PubMed:29263200). WDR11 complex facilitates the tethering of Adaptor protein-1 complex (AP-1)-derived vesicles. WDR11 complex acts together with TBC1D23 to facilitate the golgin-mediated capture of vesicles generated using AP-1 (By similarity).By similarity1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
WD repeat-containing protein 11
Alternative name(s):
Bromodomain and WD repeat-containing protein 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Wdr11
Synonyms:Brwd2, Kiaa1351
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1920230 Wdr11

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell projection, Cytoplasm, Cytoplasmic vesicle, Cytoskeleton, Golgi apparatus, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Mutants show retardation of growth and development with mid-gestation embryonic lethality, delayed puberty, reproductive dysfunctions and obesity. The rare mutant survivors through adulthood exhibit abnormal digit separation and syndactyly, as well as shortened limbs and hypoplastic skeletons with reduced or absent bone mineralization. Their head show a diminutive and curved nasal midline and a small lower jaw with microcephaly, closely spaced eyes or single/absent eyes. They have hypothalamic gonadotropin-releasing hormone (GnRH) deficiency and pituitary dysgenesis. In some cases, they exhibit exencephaly. At 12.5 dpc, they also have heart defects with a double-outlet right ventricle, ventricular septal defects and sometimes thorcic skeletal defect and lung airway abnormalities (PubMed:29263200). Mutant cells show defective ciliogenesis with a significant reduction in the length of the ciliary axoneme and the frequency of ciliated cells (PubMed:29263200).1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003098461 – 1223WD repeat-containing protein 11Add BLAST1223

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei205PhosphoserineBy similarity1
Modified residuei209PhosphoserineBy similarity1
Modified residuei401PhosphoserineCombined sources1
Modified residuei405PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8K1X1

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8K1X1

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8K1X1

PRoteomics IDEntifications database

More...
PRIDEi
Q8K1X1

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8K1X1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8K1X1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Broadly expressed in various organs including brain, eye,ear, lung, heart, kideny and gonads (PubMed:29263200). Cerebral cortex. The entire developing central nervous system, except for the spinal cord, reveals expression. Expressed in the neuroepithelium, including the diencephalic region that gives rise to hypothalamic neurons. In the adult brain, intense expression is restricted to the olfactory bulb, the olfaction-related piriform cortex, the granule cell layer of the cerebellum, and neurons of the hippocampal formation. The brain demonstrated expression scattered throughout the hypothalamus, sometimes in clusters of neurons (PubMed:20887964).2 Publications

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed in embryos from 10.5. to 14.5 dpc (PubMed:20887964, PubMed:29263200). In 10.5-12.5 dpc embryos, detected in the vesicles of the heart, branchial arches, mesonephric duct, head mesenchyme, developing eye and forebrain (PubMed:29263200). At 12.5 and 14.5 dpc, high levels of expression are particularly noteworthy in the developing cortex and the olfactory bulb (PubMed:20887964, PubMed:29263200).2 Publications

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the complex WDR11 composed of C17orf75, FAM91A1 and WDR11; FAM91A1 and WDR11 are required for proper location of the complex (By similarity).

Interacts with GLI3; the interaction associateS EMX1 with GLI3 (PubMed:29263200).

Interacts with TBC1D23; this interaction may be indirect and recruits TBC1D23 to AP-1-derived vesicles (PubMed:29084197).

Interacts (via the N-terminal and the central portion of the protein) with EMX1 (PubMed:29263200).

By similarity2 Publications

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000081567

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati59 – 108WD 1Add BLAST50
Repeati111 – 154WD 2Add BLAST44
Repeati354 – 393WD 3Add BLAST40
Repeati470 – 509WD 4Add BLAST40
Repeati565 – 604WD 5Add BLAST40
Repeati707 – 744WD 6Add BLAST38
Repeati746 – 786WD 7Add BLAST41
Repeati792 – 830WD 8Add BLAST39
Repeati892 – 939WD 9Add BLAST48

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1003 – 1006Poly-Leu4

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1912 Eukaryota
ENOG410XT4R LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000294084

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8K1X1

Database of Orthologous Groups

More...
OrthoDBi
617629at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8K1X1

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.130.10.10, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR036322 WD40_repeat_dom_sf
IPR039694 WDR11

The PANTHER Classification System

More...
PANTHERi
PTHR14593 PTHR14593, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00320 WD40, 6 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50978 SSF50978, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00678 WD_REPEATS_1, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

Q8K1X1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLPYTVNFKV SARTLTGALN AHNKAAVDWG WQGLIAYGCH SLVVVIDSNT
60 70 80 90 100
AQTLQVLEKH KADIVKVRWA RENYHHNIGS PYCLRLASAD VTGKIIVWDV
110 120 130 140 150
AAGVAQCEIQ EHVKPIQDVQ WLWNQDASRD LLLAIHPPNY IVLWNADTGT
160 170 180 190 200
KLWKKSYADN ILSFSFDPFD PSHLTLLTSE GIVFISDFSP SKPPSGPGKK
210 220 230 240 250
VYISSPHSSP AHNKLAAATG AKKALNKVKI LITQEKPSAD FVALNDCLQL
260 270 280 290 300
AYLPSKRNHM LLLYPREILI LDLEVNQTVG VIAIERTGVP FLQVIPCSQR
310 320 330 340 350
DGLFCLHENG CITLRVRRSY NSICTTSNDE PDLDPVQELT YDLRSQCDAI
360 370 380 390 400
RVTKTVRPFS MVCCPVNENA AALIVSDGRV MIWELKSAVC SRNARNSSGV
410 420 430 440 450
SPLYSPVSFC GIPGGVLQNK LPDLSLDNMI GQSAIAGEEH PKGSILQEVH
460 470 480 490 500
LKFLLTGLLS GLPSPQFAIR MCPPLTTKNI KTYQPLLAVG TSNGSVLVYH
510 520 530 540 550
LTSGLLHKEL SVHSCEVKGI EWTSLTSFLS FAASTPNNMG LVRNELQLVD
560 570 580 590 600
LPTGRSTAFR GDRGNDESPI EMIKVSHLKQ YLAVVFKDKP LELWDIRTCT
610 620 630 640 650
LLREMSKSFP AITALEWSPS HNLKSLRKKQ LATREAMARQ TVVSDAELGA
660 670 680 690 700
VESSVISLLQ EAESKAELSQ NISAREHFVF TDNDGQVYHL TVEGNSVKDS
710 720 730 740 750
ARIPPDGSMG SITCIAWKGD TLVLGDMDGN LNFWDLKARV SRGIPTHRSW
760 770 780 790 800
VRKIRFAPGK GNQKLIAMYN DGAEVWDTKE VQMVSSLRSG RNVTFRILDV
810 820 830 840 850
DWCTSDKVIL ASDDGCIRVL EMSMKSTCFR MDEQELVEPV WCPYLLVPRA
860 870 880 890 900
ALALKAFLLH QPWNGRYSLD ISHIDYPENE EIKTLLQEQL HALSNDIKKL
910 920 930 940 950
LLDPDFSLLQ RCLLVSRLYG DESELHFWTV AAHYLHSLSQ AKSGDTVVTK
960 970 980 990 1000
EGAPKDRLSN PLDICYDVLC ENTYFQKFQL ERVNLQEVKR STYDHTRKCT
1010 1020 1030 1040 1050
DQLLLLGQTD RAVQLLLETS ADNQHYYCDS LKACLVTTVT SSGPSQSTIK
1060 1070 1080 1090 1100
LVATNMIANG KLAEGVQLLC LIDKAADACR YLQTYGEWNR AAWLAKVRLN
1110 1120 1130 1140 1150
SEECADVLKR WVDHLCSPQV NQKSKALLVL LSLGCFVSVA ETLHSMRYFD
1160 1170 1180 1190 1200
RAALFVEACL KYGAFEVSED TEKLIAAIYA DYARSLKSLG FRQGAVRFAS
1210 1220
KAGAAGRDLL NELGSTKEEL TES
Length:1,223
Mass (Da):135,937
Last modified:October 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD8C945901E2C245E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G5E8J3G5E8J3_MOUSE
Bromodomain and WD repeat domain co...
Wdr11 Brwd2, mCG_22163
1,223Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0U1RQ40A0A0U1RQ40_MOUSE
WD repeat-containing protein 11
Wdr11
387Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0U1RQ34A0A0U1RQ34_MOUSE
WD repeat-containing protein 11
Wdr11
123Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0U1RPD4A0A0U1RPD4_MOUSE
WD repeat-containing protein 11
Wdr11
34Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti482T → M in BAC31449 (PubMed:16141072).Curated1
Sequence conflicti766 – 780IAMYN…WDTKE → SRMVKDFIFCQSFLQ in BAD32433 (PubMed:15368895).CuratedAdd BLAST15

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BC037177 mRNA Translation: AAH37177.1
AK043051 mRNA Translation: BAC31449.2
AK173155 mRNA Translation: BAD32433.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS40155.1

NCBI Reference Sequences

More...
RefSeqi
NP_758459.2, NM_172255.3

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
207425

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:207425

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC037177 mRNA Translation: AAH37177.1
AK043051 mRNA Translation: BAC31449.2
AK173155 mRNA Translation: BAD32433.1
CCDSiCCDS40155.1
RefSeqiNP_758459.2, NM_172255.3

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000081567

PTM databases

iPTMnetiQ8K1X1
PhosphoSitePlusiQ8K1X1

Proteomic databases

EPDiQ8K1X1
MaxQBiQ8K1X1
PaxDbiQ8K1X1
PRIDEiQ8K1X1

Genome annotation databases

GeneIDi207425
KEGGimmu:207425

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
55717
MGIiMGI:1920230 Wdr11

Rodent Unidentified Gene-Encoded large proteins database

More...
Rougei
Search...

Phylogenomic databases

eggNOGiKOG1912 Eukaryota
ENOG410XT4R LUCA
HOGENOMiHOG000294084
InParanoidiQ8K1X1
OrthoDBi617629at2759
PhylomeDBiQ8K1X1

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Wdr11 mouse

Protein Ontology

More...
PROi
PR:Q8K1X1

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Family and domain databases

Gene3Di2.130.10.10, 3 hits
InterProiView protein in InterPro
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR036322 WD40_repeat_dom_sf
IPR039694 WDR11
PANTHERiPTHR14593 PTHR14593, 1 hit
SMARTiView protein in SMART
SM00320 WD40, 6 hits
SUPFAMiSSF50978 SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS00678 WD_REPEATS_1, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiWDR11_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8K1X1
Secondary accession number(s): Q69ZL3, Q8C937
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: October 1, 2002
Last modified: November 13, 2019
This is version 132 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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