UniProtKB - Q8K1M4 (GLIS1_MOUSE)

BLAST

>sp|Q8K1M4|GLIS1_MOUSE Zinc finger protein GLIS1 OS=Mus musculus OX=10090 GN=Glis1 PE=2 SV=2
MHCEVAEALSDKRPKEAPGAPGQGRGPVSLGAHMAFRIAVSGGGCGDGNPLDLLPRLPVP
PPRAHDLLRPRSPRDYGVSKTGSGKVNGSYGHSSEKSLLDLDLAEGPSPSCHQGLFLPAG
TPPPRGHPPVCEKLLHFPHPNRSPRPQATFVNGSLPAAQHIKQEALPDYQAMVSAHTPLP
THCRAPSSMGLPSDLDFPDRGLTNPAPSCYLLGNEPISDLGPQPEAHLPEGSLKRCCLLG
LPPTSSASSSPCASSDINPVIHSSQTALVSCVNGLRSPPLPGDLGGPPKRSRPGPASSDG
QEGSLQLEACRKSGFLKQEPMDEFSELFAPHHQGLPPPYPLPQLPTGPGLGGLGLGLAGR
MVAGRQACRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKL
LIHMRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDR
AKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQQVRKKLHTGADPEADVLS
ECLSLQQLQASTLLPASRGKGSQTLSQELLPGVYPGSVTPQNGLASGILSPSHDVPSRHH
PLEVPTGSHHHLSPLPTAESTRDGLGPSLLSPMVSPLKGLGPPPLPPASQSQSPGGQSFS
TVPSKPTYPSFQSPPPLPSPQGYQGSFHSIQNCFPYADCYRATEPAASRDGLVGDAHGFN
PLRPSTYSSLSTPLSAPGYETLAETPCPPALQPQPAEDLVPSGPEDCGFFPNGAFDHCLS
HIPSIYTDT

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History
Entry version 121 (07 Nov 2018)
Sequence version 2 (21 Dec 2004)
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Protein

Zinc finger protein GLIS1

Gene

Glis1

Organism

Mus musculus (Mouse)

Status

Reviewed-Annotation score: -Experimental evidence at transcript levelⁱ

Functionⁱ

Acts as both a repressor and activator of transcription. Binds to the consensus sequence 5'-GACCACCCAC-3'.2 Publications

Regions

Feature key	Position(s)	DescriptionActions	Length
Zinc fingerⁱ	366 – 391	C2H2-type 1PROSITE-ProRule annotationAdd BLAST	26
Zinc fingerⁱ	400 – 427	C2H2-type 2; atypicalPROSITE-ProRule annotationAdd BLAST	28
Zinc fingerⁱ	433 – 457	C2H2-type 3PROSITE-ProRule annotationAdd BLAST	25
Zinc fingerⁱ	463 – 487	C2H2-type 4PROSITE-ProRule annotationAdd BLAST	25
Zinc fingerⁱ	493 – 517	C2H2-type 5PROSITE-ProRule annotationAdd BLAST	25

GO - Molecular functionⁱ

DNA binding
Source: MGI
Inferred from direct assayⁱ
- 12042312
- 12385751
DNA-binding transcription activator activity, RNA polymerase II-specific
Source: NTNU_SB
Inferred from direct assayⁱ
- 12042312
DNA-binding transcription repressor activity, RNA polymerase II-specific
Source: NTNU_SB
Inferred from direct assayⁱ
- 12042312
metal ion binding Source: UniProtKB-KW
RNA polymerase II regulatory region sequence-specific DNA binding
Source: NTNU_SB
Inferred from direct assayⁱ
- 12042312

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

negative regulation of transcription by RNA polymerase II
Source: NTNU_SB
Inferred from direct assayⁱ
- 12042312
positive regulation of transcription, DNA-templated
Source: MGI
Inferred from direct assayⁱ
- 12042312
positive regulation of transcription by RNA polymerase II
Source: UniProtKB
Inferred from direct assayⁱ
- 12042312
regulation of transcription by RNA polymerase II
Source: MGI
Inferred from direct assayⁱ
- 12385751

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Activator, DNA-binding, Repressor
Biological process	Transcription, Transcription regulation
Ligand	Metal-binding, Zinc

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Zinc finger protein GLIS1 Alternative name(s): GLI-similar 1 Gli homologous protein 1 Short name: GliH1
Gene namesⁱ	Name:Glis1Imported Synonyms:Gli5
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 4

Organism-specific databases

MGIⁱ	MGI:2386723 Glis1

Keywords - Cellular componentⁱ

Nucleus

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000047210	1 – 789	Zinc finger protein GLIS1Add BLAST		789

Proteomic databases

PaxDbⁱ	Q8K1M4
PRIDEⁱ	Q8K1M4

PTM databases

iPTMnetⁱ	Q8K1M4
PhosphoSitePlusⁱ	Q8K1M4

Expressionⁱ

Tissue specificityⁱ

In the adult, expressed highly in placenta and kidney and at lower levels in the testis, brain, colon, brown fat tissue and thymus. During embryo development, expressed in the frontal nasal region, branchial arches, somites, vibrissal and hair follicles, limb buds, craniofacial regions, ventral part of the tail, intervertebral disks, teeth, eyes and kidney.2 Publications

Developmental stageⁱ

In the embryo, expression is detected at 10 dpc becoming stronger by 11 dpc and continuing through to 16.5 dpc.2 Publications

Gene expression databases

Bgeeⁱ	ENSMUSG00000034762 Expressed in 135 organ(s), highest expression level in embryo
CleanExⁱ	MM_GLIS1
ExpressionAtlasⁱ	Q8K1M4 baseline and differential
Genevisibleⁱ	Q8K1M4 MM

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	10090.ENSMUSP00000035650

STRINGⁱ

10090.ENSMUSP00000035650

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q8K1M4
SMRⁱ	Q8K1M4
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Motif

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Motifⁱ	511 – 527	Bipartite nuclear localization signalSequence analysisAdd BLAST		17

Compositional bias

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Compositional biasⁱ	627 – 680	Pro-richAdd BLAST		54

Sequence similaritiesⁱ

Belongs to the GLI C2H2-type zinc-finger protein family.Curated

Zinc finger

Feature key	Position(s)	DescriptionActions	Length
Zinc fingerⁱ	366 – 391	C2H2-type 1PROSITE-ProRule annotationAdd BLAST	26
Zinc fingerⁱ	400 – 427	C2H2-type 2; atypicalPROSITE-ProRule annotationAdd BLAST	28
Zinc fingerⁱ	433 – 457	C2H2-type 3PROSITE-ProRule annotationAdd BLAST	25
Zinc fingerⁱ	463 – 487	C2H2-type 4PROSITE-ProRule annotationAdd BLAST	25
Zinc fingerⁱ	493 – 517	C2H2-type 5PROSITE-ProRule annotationAdd BLAST	25

Keywords - Domainⁱ

Repeat, Zinc-finger

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00900000140802
HOGENOMⁱ	HOG000231136
HOVERGENⁱ	HBG051736
InParanoidⁱ	Q8K1M4
KEGG Orthology (KO) More...KOⁱ	K09232
OMAⁱ	KPPYPPF
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0IZP
PhylomeDBⁱ	Q8K1M4
TreeFamⁱ	TF350216

Family and domain databases

InterProⁱ	View protein in InterPro IPR030430 GLIS1 IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
PANTHERⁱ	PTHR19818:SF93 PTHR19818:SF93, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00096 zf-C2H2, 3 hits
SMARTⁱ	View protein in SMART SM00355 ZnF_C2H2, 5 hits
SUPFAMⁱ	SSF57667 SSF57667, 3 hits
PROSITEⁱ	View protein in PROSITE PS00028 ZINC_FINGER_C2H2_1, 4 hits PS50157 ZINC_FINGER_C2H2_2, 4 hits

Sequences (2+)ⁱ

Sequence statusⁱ: Complete.

This entry describes 2 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show all Align All

Isoform 11 Publication (identifier: Q8K1M4-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MHCEVAEALS DKRPKEAPGA PGQGRGPVSL GAHMAFRIAV SGGGCGDGNP 
        60         70         80         90        100
LDLLPRLPVP PPRAHDLLRP RSPRDYGVSK TGSGKVNGSY GHSSEKSLLD 
       110        120        130        140        150
LDLAEGPSPS CHQGLFLPAG TPPPRGHPPV CEKLLHFPHP NRSPRPQATF 
       160        170        180        190        200
VNGSLPAAQH IKQEALPDYQ AMVSAHTPLP THCRAPSSMG LPSDLDFPDR 
       210        220        230        240        250
GLTNPAPSCY LLGNEPISDL GPQPEAHLPE GSLKRCCLLG LPPTSSASSS 
       260        270        280        290        300
PCASSDINPV IHSSQTALVS CVNGLRSPPL PGDLGGPPKR SRPGPASSDG 
       310        320        330        340        350
QEGSLQLEAC RKSGFLKQEP MDEFSELFAP HHQGLPPPYP LPQLPTGPGL 
       360        370        380        390        400
GGLGLGLAGR MVAGRQACRW VDCCAAYEQQ EELVRHIEKS HIDQRKGEDF 
       410        420        430        440        450
TCFWAGCVRR YKPFNARYKL LIHMRVHSGE KPNKCMFEGC SKAFSRLENL 
       460        470        480        490        500
KIHLRSHTGE KPYLCQHPGC QKAFSNSSDR AKHQRTHLDT KPYACQIPGC 
       510        520        530        540        550
SKRYTDPSSL RKHVKAHSAK EQQVRKKLHT GADPEADVLS ECLSLQQLQA 
       560        570        580        590        600
STLLPASRGK GSQTLSQELL PGVYPGSVTP QNGLASGILS PSHDVPSRHH 
       610        620        630        640        650
PLEVPTGSHH HLSPLPTAES TRDGLGPSLL SPMVSPLKGL GPPPLPPASQ 
       660        670        680        690        700
SQSPGGQSFS TVPSKPTYPS FQSPPPLPSP QGYQGSFHSI QNCFPYADCY 
       710        720        730        740        750
RATEPAASRD GLVGDAHGFN PLRPSTYSSL STPLSAPGYE TLAETPCPPA 
       760        770        780 
LQPQPAEDLV PSGPEDCGFF PNGAFDHCLS HIPSIYTDT

Length:789

Mass (Da):84,172

Last modified:December 21, 2004 - v2

Checksum:ⁱ98D87D9EA20D38FD

Isoform 21 Publication (identifier: Q8K1M4-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
1-171: Missing.

« Hide

        10         20         30         40         50
MVSAHTPLPT HCRAPSSMGL PSDLDFPDRG LTNPAPSCYL LGNEPISDLG 
        60         70         80         90        100
PQPEAHLPEG SLKRCCLLGL PPTSSASSSP CASSDINPVI HSSQTALVSC 
       110        120        130        140        150
VNGLRSPPLP GDLGGPPKRS RPGPASSDGQ EGSLQLEACR KSGFLKQEPM 
       160        170        180        190        200
DEFSELFAPH HQGLPPPYPL PQLPTGPGLG GLGLGLAGRM VAGRQACRWV 
       210        220        230        240        250
DCCAAYEQQE ELVRHIEKSH IDQRKGEDFT CFWAGCVRRY KPFNARYKLL 
       260        270        280        290        300
IHMRVHSGEK PNKCMFEGCS KAFSRLENLK IHLRSHTGEK PYLCQHPGCQ 
       310        320        330        340        350
KAFSNSSDRA KHQRTHLDTK PYACQIPGCS KRYTDPSSLR KHVKAHSAKE 
       360        370        380        390        400
QQVRKKLHTG ADPEADVLSE CLSLQQLQAS TLLPASRGKG SQTLSQELLP 
       410        420        430        440        450
GVYPGSVTPQ NGLASGILSP SHDVPSRHHP LEVPTGSHHH LSPLPTAEST 
       460        470        480        490        500
RDGLGPSLLS PMVSPLKGLG PPPLPPASQS QSPGGQSFST VPSKPTYPSF 
       510        520        530        540        550
QSPPPLPSPQ GYQGSFHSIQ NCFPYADCYR ATEPAASRDG LVGDAHGFNP 
       560        570        580        590        600
LRPSTYSSLS TPLSAPGYET LAETPCPPAL QPQPAEDLVP SGPEDCGFFP 
       610 
NGAFDHCLSH IPSIYTDT

Show »

Length:618

Mass (Da):66,209

Checksum:ⁱ25055F3D35CECBF1

Computationally mapped potential isoform sequencesⁱ

There are 2 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

B1ASP5	B1ASP5_MOUSE	Zinc finger protein GLIS1 Zinc finger protein GLIS1	Glis1	601	Annotation score:
A2A8S0	A2A8S0_MOUSE	Zinc finger protein GLIS1 Zinc finger protein GLIS1	Glis1	104	Annotation score:

Sequence cautionⁱ

The sequence AAH66157 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature key	Position(s)	DescriptionActions	Length
Sequence conflictⁱ	173	V → A in AAM93156 (PubMed:12042312).Curated	1
Sequence conflictⁱ	354	G → R in AAM93156 (PubMed:12042312).Curated	1
Sequence conflictⁱ	378	E → G in AAH66157 (PubMed:15489334).Curated	1
Sequence conflictⁱ	384	V → E in AAH66157 (PubMed:15489334).Curated	1
Sequence conflictⁱ	466	Q → R in AAM93156 (PubMed:12042312).Curated	1
Sequence conflictⁱ	634	V → A in AAH66157 (PubMed:15489334).Curated	1
Sequence conflictⁱ	668	Y → S in AAH66157 (PubMed:15489334).Curated	1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_051623	1 – 171	Missing in isoform 2. 1 PublicationAdd BLAST		171

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF486579 mRNA Translation: AAM93156.1 AF220434 mRNA Translation: AAM12150.1 BC066157 mRNA Translation: AAH66157.1 Different initiation.
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS38831.1 [Q8K1M4-1]
NCBI Reference Sequences More...RefSeqⁱ	NP_671754.2, NM_147221.2 [Q8K1M4-1] XP_006503036.1, XM_006502973.3 [Q8K1M4-1] XP_006503037.1, XM_006502974.3 [Q8K1M4-1] XP_006503038.1, XM_006502975.1 [Q8K1M4-1]
UniGeneⁱ	Mm.331757

Genome annotation databases

Ensemblⁱ	ENSMUST00000046005; ENSMUSP00000035650; ENSMUSG00000034762 [Q8K1M4-1]
GeneIDⁱ	230587
KEGGⁱ	mmu:230587
UCSC genome browser More...UCSCⁱ	uc008tzv.1 mouse [Q8K1M4-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q8K1M4	Zinc finger protein GLIS1 (Fragment)		MOUSE		104	UniRef100_Q8K1M4
Zinc finger protein GLIS1		MOUSE		601
Isoform 2 of Zinc finger protein GLIS1		MOUSE		618
UPI0003D71195		MOUSE		804

Protein	Similar proteins		Species	Score	Length	Source
Q8K1M4	Zinc finger protein GLIS1 (Fragment)		MOUSE		104	UniRef90_Q8K1M4
zinc finger protein GLIS1 isoform X1		MESAU		794
GLIS family zinc finger 1		RAT		708
Zinc finger protein GLIS1 (Fragment)		CRIGR		707
UPI00038BE20C		MICOH		792
+14

Protein	Similar proteins		Species	Score	Length	Source
Q8K1M4	Zinc finger protein GLIS1		HUMAN		620	UniRef50_Q8K1M4
Zinc finger protein GLIS1 (Fragment)		MOUSE		104
zinc finger protein GLIS1 isoform X1		MESAU		794
GLIS family zinc finger 1		RAT		708
Zinc finger protein GLIS1 (Fragment)		CRIGR		707
+165

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF486579 mRNA Translation: AAM93156.1 AF220434 mRNA Translation: AAM12150.1 BC066157 mRNA Translation: AAH66157.1 Different initiation.
CCDSⁱ	CCDS38831.1 [Q8K1M4-1]
RefSeqⁱ	NP_671754.2, NM_147221.2 [Q8K1M4-1] XP_006503036.1, XM_006502973.3 [Q8K1M4-1] XP_006503037.1, XM_006502974.3 [Q8K1M4-1] XP_006503038.1, XM_006502975.1 [Q8K1M4-1]
UniGeneⁱ	Mm.331757

3D structure databases

ProteinModelPortalⁱ	Q8K1M4
SMRⁱ	Q8K1M4
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10090.ENSMUSP00000035650

STRINGⁱ

10090.ENSMUSP00000035650

PTM databases

iPTMnetⁱ	Q8K1M4
PhosphoSitePlusⁱ	Q8K1M4

Proteomic databases

PaxDbⁱ	Q8K1M4
PRIDEⁱ	Q8K1M4

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000046005; ENSMUSP00000035650; ENSMUSG00000034762 [Q8K1M4-1]
GeneIDⁱ	230587
KEGGⁱ	mmu:230587
UCSCⁱ	uc008tzv.1 mouse [Q8K1M4-1]

Organism-specific databases

CTDⁱ	148979
MGIⁱ	MGI:2386723 Glis1

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
GeneTreeⁱ	ENSGT00900000140802
HOGENOMⁱ	HOG000231136
HOVERGENⁱ	HBG051736
InParanoidⁱ	Q8K1M4
KOⁱ	K09232
OMAⁱ	KPPYPPF
OrthoDBⁱ	EOG091G0IZP
PhylomeDBⁱ	Q8K1M4
TreeFamⁱ	TF350216

Miscellaneous databases

ChiTaRSⁱ	Glis1 mouse
Protein Ontology More...PROⁱ	PR:Q8K1M4
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000034762 Expressed in 135 organ(s), highest expression level in embryo
CleanExⁱ	MM_GLIS1
ExpressionAtlasⁱ	Q8K1M4 baseline and differential
Genevisibleⁱ	Q8K1M4 MM

Family and domain databases

InterProⁱ	View protein in InterPro IPR030430 GLIS1 IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
PANTHERⁱ	PTHR19818:SF93 PTHR19818:SF93, 1 hit
Pfamⁱ	View protein in Pfam PF00096 zf-C2H2, 3 hits
SMARTⁱ	View protein in SMART SM00355 ZnF_C2H2, 5 hits
SUPFAMⁱ	SSF57667 SSF57667, 3 hits
PROSITEⁱ	View protein in PROSITE PS00028 ZINC_FINGER_C2H2_1, 4 hits PS50157 ZINC_FINGER_C2H2_2, 4 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	GLIS1_MOUSE
Accessionⁱ	Q8K1M4Primary (citable) accession number: Q8K1M4 Secondary accession number(s): Q6NZF6, Q8R4Z3
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	December 21, 2004
	Last sequence update:	December 21, 2004
	Last modified:	November 7, 2018
	This is version 121 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

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UniParc

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UniRef

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Supporting data

UniProtKB - Q8K1M4 (GLIS1_MOUSE)

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Zinc finger protein GLIS1

Glis1

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Nucleus

Keywords - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Motif

Compositional bias

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Keywords - Domaini

Phylogenomic databases

Family and domain databases

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Experimental Info

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Sequence cautionⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ