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Entry version 134 (13 Nov 2019)
Sequence version 1 (01 Oct 2002)
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Protein

Dyslexia-associated protein KIAA0319-like protein

Gene

Kiaa0319l

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Possible role in axon guidance through interaction with RTN4R.By similarity
(Microbial infection) Acts as a receptor for adeno-associated virus and is involved in adeno-associated virus infection through endocytosis system.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Dyslexia-associated protein KIAA0319-like proteinBy similarity
Alternative name(s):
Adeno-associated virus receptorBy similarity
Short name:
AAVRBy similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Kiaa0319lBy similarity
Synonyms:Aavr1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2140475 AU040320

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 29CytoplasmicSequence analysisAdd BLAST29
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei30 – 50HelicalSequence analysisAdd BLAST21
Topological domaini51 – 928ExtracellularSequence analysisAdd BLAST878
Transmembranei929 – 949HelicalSequence analysisAdd BLAST21
Topological domaini950 – 1048CytoplasmicSequence analysisAdd BLAST99

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell membrane, Golgi apparatus, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Homozygous knockout mice Kiaa0319l are normal.1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003290651 – 1048Dyslexia-associated protein KIAA0319-like proteinAdd BLAST1048

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi246N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi394N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei973PhosphothreonineBy similarity1
Modified residuei977PhosphoserineBy similarity1
Modified residuei1008PhosphoserineCombined sources1
Modified residuei1030PhosphoserineBy similarity1
Modified residuei1036PhosphothreonineBy similarity1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

N-glycosylated.By similarity

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

The CPTAC Assay portal

More...
CPTACi
non-CPTAC-3586

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8K135

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8K135

PeptideAtlas

More...
PeptideAtlasi
Q8K135

PRoteomics IDEntifications database

More...
PRIDEi
Q8K135

PTM databases

GlyConnect protein glycosylation platform

More...
GlyConnecti
2269
2422 [Q8K135-2]

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8K135

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8K135

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q8K135

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000028830 Expressed in 291 organ(s), highest expression level in small intestine

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8K135 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8K135 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with RTN4R.

By similarity

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000099667

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini49 – 127MANSCPROSITE-ProRule annotationAdd BLAST79
Domaini309 – 400PKD 1PROSITE-ProRule annotationAdd BLAST92
Domaini408 – 497PKD 2PROSITE-ProRule annotationAdd BLAST90
Domaini503 – 593PKD 3PROSITE-ProRule annotationAdd BLAST91
Domaini599 – 687PKD 4PROSITE-ProRule annotationAdd BLAST89
Domaini693 – 784PKD 5PROSITE-ProRule annotationAdd BLAST92

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IFQB Eukaryota
ENOG410XQ5Y LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000157613

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8K135

Identification of Orthologs from Complete Genome Data

More...
OMAi
FLAEWSV

Database of Orthologous Groups

More...
OrthoDBi
476157at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8K135

TreeFam database of animal gene trees

More...
TreeFami
TF323356

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 5 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR013783 Ig-like_fold
IPR029865 KIAA0319-like
IPR013980 MANSC_dom
IPR022409 PKD/Chitinase_dom
IPR000601 PKD_dom
IPR035986 PKD_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR46182:SF3 PTHR46182:SF3, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00089 PKD, 5 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49299 SSF49299, 4 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50986 MANSC, 1 hit
PS50093 PKD, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8K135-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MEKRLGVKPS PASWVLPGYC WQTSVKLPRS LYLLYSFFCF SVLWLSTDAD
60 70 80 90 100
ESRCQQGKTL YGAGLRTEGE NHLRLLAGSL PFHACRAACC RDSACHALWW
110 120 130 140 150
LEGMCFQADC SKPQSCQPFR TDSSNSMLII FQKSQTTDDL GLLPEDDEPH
160 170 180 190 200
LLRLGWGRTS WRRQSLLGAP LTLSVPSSHH QSLLRDRQKR DLSVVPTHGA
210 220 230 240 250
MQHSKVNHSE EAGALSPTSA EVRKTITVAG SFTSNHTTQT PEWPKNVSIH
260 270 280 290 300
PEPSEHSSPV SGTPQVKSTE HSPTDAPLPV APSYSYATPT PQASSQSTSA
310 320 330 340 350
PHPVVKELVV SAGKSVQITL PKNEVQLNAF VLPEAEPGET YTYDWQLITH
360 370 380 390 400
PTDYSGEVER KHSQSLQLSK LTPGLYEFKV TVDGQNAHGE GYVNVTVKPE
410 420 430 440 450
PRKNRPPVAV VSPQFQEISL PTTSTIIDGS QSTDDDKIVQ YHWEELKGPL
460 470 480 490 500
REEKISEDTA ILKLSKLVPG NYTFSLTVVD SDGATNSTTA SLTVNKAVDY
510 520 530 540 550
PPVANAGPNQ VITLPQNSIT LFGNQSTDDH GITSYEWSLS PSSKGKVVEM
560 570 580 590 600
QGVRTPALQL SAMQEGDYTY QLTVTDTAGQ QATAQVTVIV QPENNKPPQA
610 620 630 640 650
DAGPDKELTL PVDSTTLDGS KSTDDQRVVS YLWEQSRGPD GVQLENANSS
660 670 680 690 700
VATVTGLQVG TYVFTLTVKD ERNLQSQSSV NVIVKEEINK PPVAKIAGNV
710 720 730 740 750
VVTLPTSTAE LDGSRSSDDK GIVSYLWTRD ETSPAAGEVL NHSDHHPVLF
760 770 780 790 800
LSNLVEGTYT FHLKVTDAKG ESDTDRTTVE VKPDPRKSNL VEIILDVNVS
810 820 830 840 850
QLTERLKGML IRQIGVLLGV LDSDIIVQKI QPYTEQSTKM LFFVQNDPPH
860 870 880 890 900
QLFKGHEVAA MLKSELQKQK ADFLIFRALE ISTVTCQLNC SDHGHCDSFT
910 920 930 940 950
KRCVCDPFWM ENFIKVQLRD GDSNCEWSVL YVIIASFVIV VALGILSWTT
960 970 980 990 1000
ICCCKRQKGK PKRKSRYKIL DATDQESLEL KPTSRAGSKQ KGPTLSSSLM
1010 1020 1030 1040
HSESELDSDD AIFTWPDREK GKLLYGQNGS VPNGQTPLKS RSAREEIL
Length:1,048
Mass (Da):115,312
Last modified:October 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF4D51DD6DE4C889D
GO
Isoform 2 (identifier: Q8K135-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1025-1048: YGQNGSVPNGQTPLKSRSAREEIL → ALHWCRSQSL...RTKSALVHGK

Note: No experimental confirmation available.
Show »
Length:1,085
Mass (Da):119,438
Checksum:i64CCADE9B26E84E0
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Z4YK56Z4YK56_MOUSE
Expressed sequence AU040320
AU040320
1,085Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A2A788A2A788_MOUSE
Expressed sequence AU040320
AU040320
124Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A2A786A2A786_MOUSE
Expressed sequence AU040320
AU040320
87Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A2A787A2A787_MOUSE
Expressed sequence AU040320
AU040320
92Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH22154 differs from that shown. Contaminating sequence. Sequence of unknown origin in the N-terminal part.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti4R → G in BAC39244 (PubMed:16141072).Curated1
Sequence conflicti579Missing in BAE36422 (PubMed:16141072).Curated1
Sequence conflicti656G → V in BAC33818 (PubMed:16141072).Curated1
Sequence conflicti684V → A in BAC33818 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0329561025 – 1048YGQNG…REEIL → ALHWCRSQSLHHIGWWCRAP VCHETSSTNSTPGSDSGFCK GGKNLSSDYRTRTKSALVHG K in isoform 2. 1 PublicationAdd BLAST24

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK043006 mRNA Translation: BAC31432.1
AK049570 mRNA Translation: BAC33818.1
AK084668 mRNA Translation: BAC39244.1
AK147569 mRNA Translation: BAE27999.1
AK161493 mRNA Translation: BAE36422.1
AK170261 mRNA Translation: BAE41669.1
AL606908 Genomic DNA No translation available.
BC022154 mRNA Translation: AAH22154.1 Sequence problems.
BC028869 mRNA Translation: AAH28869.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS18660.1 [Q8K135-2]
CCDS18661.1 [Q8K135-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001030602.1, NM_001035525.1
NP_001030603.1, NM_001035526.1
NP_598647.1, NM_133886.2 [Q8K135-1]
XP_017175383.1, XM_017319894.1 [Q8K135-1]
XP_017175384.1, XM_017319895.1 [Q8K135-1]
XP_017175385.1, XM_017319896.1 [Q8K135-1]
XP_017175386.1, XM_017319897.1 [Q8K135-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000047431; ENSMUSP00000037802; ENSMUSG00000028830 [Q8K135-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
100317

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
mmu:100317

UCSC genome browser

More...
UCSCi
uc008utw.1 mouse [Q8K135-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK043006 mRNA Translation: BAC31432.1
AK049570 mRNA Translation: BAC33818.1
AK084668 mRNA Translation: BAC39244.1
AK147569 mRNA Translation: BAE27999.1
AK161493 mRNA Translation: BAE36422.1
AK170261 mRNA Translation: BAE41669.1
AL606908 Genomic DNA No translation available.
BC022154 mRNA Translation: AAH22154.1 Sequence problems.
BC028869 mRNA Translation: AAH28869.1
CCDSiCCDS18660.1 [Q8K135-2]
CCDS18661.1 [Q8K135-1]
RefSeqiNP_001030602.1, NM_001035525.1
NP_001030603.1, NM_001035526.1
NP_598647.1, NM_133886.2 [Q8K135-1]
XP_017175383.1, XM_017319894.1 [Q8K135-1]
XP_017175384.1, XM_017319895.1 [Q8K135-1]
XP_017175385.1, XM_017319896.1 [Q8K135-1]
XP_017175386.1, XM_017319897.1 [Q8K135-1]

3D structure databases

Database of comparative protein structure models

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ModBasei
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SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000099667

PTM databases

GlyConnecti2269
2422 [Q8K135-2]
iPTMnetiQ8K135
PhosphoSitePlusiQ8K135
SwissPalmiQ8K135

Proteomic databases

CPTACinon-CPTAC-3586
EPDiQ8K135
PaxDbiQ8K135
PeptideAtlasiQ8K135
PRIDEiQ8K135

Genome annotation databases

EnsembliENSMUST00000047431; ENSMUSP00000037802; ENSMUSG00000028830 [Q8K135-1]
GeneIDi100317
KEGGimmu:100317
UCSCiuc008utw.1 mouse [Q8K135-1]

Organism-specific databases

MGIiMGI:2140475 AU040320

Phylogenomic databases

eggNOGiENOG410IFQB Eukaryota
ENOG410XQ5Y LUCA
GeneTreeiENSGT00940000157613
InParanoidiQ8K135
OMAiFLAEWSV
OrthoDBi476157at2759
PhylomeDBiQ8K135
TreeFamiTF323356

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
AU040320 mouse

Protein Ontology

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PROi
PR:Q8K135

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSMUSG00000028830 Expressed in 291 organ(s), highest expression level in small intestine
ExpressionAtlasiQ8K135 baseline and differential
GenevisibleiQ8K135 MM

Family and domain databases

Gene3Di2.60.40.10, 5 hits
InterProiView protein in InterPro
IPR013783 Ig-like_fold
IPR029865 KIAA0319-like
IPR013980 MANSC_dom
IPR022409 PKD/Chitinase_dom
IPR000601 PKD_dom
IPR035986 PKD_dom_sf
PANTHERiPTHR46182:SF3 PTHR46182:SF3, 1 hit
SMARTiView protein in SMART
SM00089 PKD, 5 hits
SUPFAMiSSF49299 SSF49299, 4 hits
PROSITEiView protein in PROSITE
PS50986 MANSC, 1 hit
PS50093 PKD, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiK319L_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8K135
Secondary accession number(s): A2A790
, Q3TTA3, Q8BHR5, Q8BHU7, Q8BHZ3, Q8VBZ9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: October 1, 2002
Last modified: November 13, 2019
This is version 134 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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