Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 146 (18 Sep 2019)
Sequence version 3 (10 Jul 2007)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Protein unc-13 homolog C

Gene

Unc13c

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May play a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. May be involved in the regulation of synaptic transmission at parallel fiber - Purkinje cell synapses.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri1093 – 1143Phorbol-ester/DAG-typePROSITE-ProRule annotationAdd BLAST51

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processExocytosis
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein unc-13 homolog C
Alternative name(s):
Munc13-3
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Unc13c
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 9

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2149021 Unc13c

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell junction, Cell membrane, Cytoplasm, Membrane, Synapse

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Mutant mice showed no obvious physical or behavioral abnormalities. Some deficiency in motor learning can be observed, compared to wild type, in a motor performance and learning test on a rotating rod, but only at high rotation speed.1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001885791 – 2210Protein unc-13 homolog CAdd BLAST2210

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei89PhosphoserineBy similarity1
Modified residuei446PhosphoserineBy similarity1
Modified residuei450PhosphoserineBy similarity1
Modified residuei784PhosphoserineBy similarity1
Modified residuei1023Omega-N-methylarginineCombined sources1

Keywords - PTMi

Methylation, Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8K0T7

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8K0T7

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8K0T7

PeptideAtlas

More...
PeptideAtlasi
Q8K0T7

PRoteomics IDEntifications database

More...
PRIDEi
Q8K0T7

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8K0T7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8K0T7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Restricted to cerebellum, predominantly in the granule cell layer. Almost exclusively present in the molecular layer in which the parallel fiber axons of granule cells terminate on dendrites of Purkinje neurons (at protein level).1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000062151 Expressed in 167 organ(s), highest expression level in cleaving embryo

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8K0T7 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with STX1A and/or STX1B1, VAMP2 and SNAP25.

By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000139027

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8K0T7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1203 – 1309C2 1PROSITE-ProRule annotationAdd BLAST107
Domaini1633 – 1776MHD1PROSITE-ProRule annotationAdd BLAST144
Domaini1882 – 2024MHD2PROSITE-ProRule annotationAdd BLAST143
Domaini2044 – 2149C2 2PROSITE-ProRule annotationAdd BLAST106

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili967 – 991Sequence analysisAdd BLAST25

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The C2 domains are not involved in calcium-dependent phospholipid binding.By similarity

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the unc-13 family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri1093 – 1143Phorbol-ester/DAG-typePROSITE-ProRule annotationAdd BLAST51

Keywords - Domaini

Coiled coil, Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1011 Eukaryota
ENOG410XS5D LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155174

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000154775

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8K0T7

KEGG Orthology (KO)

More...
KOi
K15293

Identification of Orthologs from Complete Genome Data

More...
OMAi
MMYRSQS

Database of Orthologous Groups

More...
OrthoDBi
117172at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8K0T7

TreeFam database of animal gene trees

More...
TreeFami
TF312844

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00029 C1, 1 hit
cd04027 C2B_Munc13, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.150, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000008 C2_dom
IPR035892 C2_domain_sf
IPR010439 CAPS_dom
IPR014770 Munc13_1
IPR014772 Munc13_dom-2
IPR019558 Munc13_subgr_dom-2
IPR002219 PE/DAG-bd
IPR027080 Unc-13
IPR037302 Unc-13_C2B
IPR027087 Unc13C

The PANTHER Classification System

More...
PANTHERi
PTHR10480 PTHR10480, 1 hit
PTHR10480:SF2 PTHR10480:SF2, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00130 C1_1, 1 hit
PF00168 C2, 2 hits
PF06292 DUF1041, 1 hit
PF10540 Membr_traf_MHD, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00360 C2DOMAIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00109 C1, 1 hit
SM00239 C2, 2 hits
SM01145 DUF1041, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50004 C2, 2 hits
PS51258 MHD1, 1 hit
PS51259 MHD2, 1 hit
PS00479 ZF_DAG_PE_1, 1 hit
PS50081 ZF_DAG_PE_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q8K0T7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVASLFKSLI LAYIHKLCKG MFTKKLGNTT KKKENRQQKK DQDFPTAGHT
60 70 80 90 100
KPPKLSNALK STVKKIAKCS STRNFSIEDE EGHKDFSLSP TFSYRVAIAN
110 120 130 140 150
GLQTAVTNSD EDLLQELSSI ESSYSESFNE LRSSTENQVQ STHTMPVRRN
160 170 180 190 200
RKSSSSLAPS EGSSDGERTL HTLKLGALRK LRKWKKSQEC VSSDSELSTV
210 220 230 240 250
KKTWGIRSKS LDRTARNPKT NVLEPGFSSS GCISQTHDVM EMIFKELQGI
260 270 280 290 300
SQIETELSEL RGHVNALKYS IDEISSSVEV VQSEIEQLRT GFVQARRETR
310 320 330 340 350
DIHDYIKHLG HMGSKVSLRF LNVPEERHEY VESVVYQILI DKMGFSDVPN
360 370 380 390 400
AIKIEFAQRI GQQRDCPNAK PRPILVYFET PQQRDSVLKK SYKLKGTGIG
410 420 430 440 450
ISTDILTYDI RERKEKGVLP SSQTYESMDM KLSTPEPKAK KNAWLSPNDS
460 470 480 490 500
DRELESDLSR SSYADSPAKG SSSKSSSKSH SARSKNKAAN SRTSQKSDYN
510 520 530 540 550
KRPSQPPASS TPEKQTPHYV EATPPLWHSQ SDFFTLKLSR SESDFSKLCQ
560 570 580 590 600
SYSEDFSESQ FFCRTNGSSL LSSSDRELWQ RKQEGMPALY HRLQDQGLDE
610 620 630 640 650
TIPAVPGQAE IENTETVDSG MSNSMVCASG DRSNYSGSQL SLHEDLSPWK
660 670 680 690 700
EWNQAGQGTD DVGLDSSTQE PFDYDTNSLS DQQLDLSSKD LDDLGKCHSD
710 720 730 740 750
LQDDSESYDL TQDDNSSPCP GLDNEPQGQW VGQYDSYQEA NSNDLYPNQS
760 770 780 790 800
HPSMMYRSQS ELQSDDSEGA QPKSWHSRLS IDLSDKTFKF PKFGSTLQRA
810 820 830 840 850
KSALEVVWNK STQSLSGCED SGSSLMGRFR TLSQSTANES STTLDSDIYT
860 870 880 890 900
EPYYYKAEEE EDYCEPVADS ETDYVEVMEQ VLAKLENRTS ITEVNEHIKD
910 920 930 940 950
YDHPSYETPY ETPQDEGYDG QADDIISEGE LETLNEPAVE MELAEDENQN
960 970 980 990 1000
LPAESLEVMK PKRIRPSFKE AALRAYKKQM AELEEKILAG DSSSMDEKAR
1010 1020 1030 1040 1050
IVSGNDLDAS KFSALQVFGG AGRGLYGIDS MPDLRRKKTL PIVRDVAMTL
1060 1070 1080 1090 1100
AARKSGLSLA MVIRTSLNNE ELKMHVFRKT LQALIYPISS TTPHNFEVWT
1110 1120 1130 1140 1150
ATTPTYCYEC EGLLWGIARQ GMKCLECGVK CHEKCQDLLN ADCLQRAAEK
1160 1170 1180 1190 1200
SSKHGAEDKT QTIITAMKER MKIRERNRPE VFEVIQEMFQ ISKEDFVQYT
1210 1220 1230 1240 1250
KAAKQSVLDG TSKWSAKITI TVVSAQGLQA KDKTGSSDPY VTVQVGKNKR
1260 1270 1280 1290 1300
RTKTIFGNLN PVWDEKFFFE CHNSTDRIKV RVWDEDDDIK SRVKQHFKKE
1310 1320 1330 1340 1350
SDDFLGQTIV EVRTLSGEMD VWYNLEKRTD KSAVSGAIRL KINVEIKGEE
1360 1370 1380 1390 1400
KVAPYHIQYT CLHENLFHYL TEVKSNGSVK IPEVKGDEAW KVFFDDASQE
1410 1420 1430 1440 1450
IVDEFAMRYG VESIYQAMTH FSCLSSKYMC PGVPAVMSAL LANINAFYAH
1460 1470 1480 1490 1500
TTVSTNVQVS ASDRFAATNF GREKFIKLLD QLHNSLRIDL SKYRENFPAS
1510 1520 1530 1540 1550
NSERLQDLKS TVDLLTSITF FRMKVLELQS PPKASAVVKD CVRACLDSTY
1560 1570 1580 1590 1600
KYIFDNCHEL YSQLIDPSKK QDVPREDQGP TTKNLDFWPQ LITLMVTIID
1610 1620 1630 1640 1650
EDKTAYTPVL NQFPQELNMG KISAEIMWSL FALDMKYALE EHEKQRLCKS
1660 1670 1680 1690 1700
TDYMNLHFKV KWFYNEYVRE LPAFKDAVPE YSLWFEPFVM QWLDENEDVS
1710 1720 1730 1740 1750
MEFLHGALGR DKKDGFQQTS DHALFSCSVV DVFAQLNQSF EIIKKLECPN
1760 1770 1780 1790 1800
PEALSHLMRR FAKTINKVLV QYAAIVSNDF SSYCDKETVP CILMNNIQQL
1810 1820 1830 1840 1850
RVQLEKMFES MGGKELDPEA STILKELQIK LNGVLDALSI TYGESFQLTI
1860 1870 1880 1890 1900
EECIKQMGAE LNQMRANGNS TANKNSAAMD AEIVLRPLMD FLDKTLSLSA
1910 1920 1930 1940 1950
KICEKTVLKR VLKELWKLVL NKIEKQIVLP PLTDQTGPQM IFIAAKDLGQ
1960 1970 1980 1990 2000
LSKLKEHMIR EDAKGLTPRQ CAIVEVVLAT IKQYFHAGGN GLKKNFLEKS
2010 2020 2030 2040 2050
PDLHSLRYAL SLYTQTTDAL IKKFIETQGS QSRSSKDAVG QISVHVDVTT
2060 2070 2080 2090 2100
TPGTGDHKVT VKVIAINDLN WQTTAMFRPF VEVCMLGPSL GDKKRKQGTK
2110 2120 2130 2140 2150
TKSNTWSPKY NETFQFILGN ENRPGAYELH LSVKDYCFAR EDRIIGMTVI
2160 2170 2180 2190 2200
QLQNIAEKGS YGAWYPLLKN LSMDETGLTI LRILSQRTSD DVAKEFVRLK
2210
SETRSIEESA
Length:2,210
Mass (Da):249,844
Last modified:July 10, 2007 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iED6A02639FC6FA3F
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH30416 differs from that shown. Contaminating sequence. Sequence of unknown origin in the N- terminal and C-terminal parts.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC112267 Genomic DNA No translation available.
AC124451 Genomic DNA No translation available.
AC131722 Genomic DNA No translation available.
AC132267 Genomic DNA No translation available.
AC153359 Genomic DNA No translation available.
AK005367 mRNA No translation available.
BC030416 mRNA Translation: AAH30416.1 Sequence problems.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS40690.1

NCBI Reference Sequences

More...
RefSeqi
NP_001074622.1, NM_001081153.1
XP_006510996.1, XM_006510933.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000075245; ENSMUSP00000074726; ENSMUSG00000062151
ENSMUST00000184666; ENSMUSP00000139027; ENSMUSG00000062151

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
208898

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:208898

UCSC genome browser

More...
UCSCi
uc033jlk.1 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC112267 Genomic DNA No translation available.
AC124451 Genomic DNA No translation available.
AC131722 Genomic DNA No translation available.
AC132267 Genomic DNA No translation available.
AC153359 Genomic DNA No translation available.
AK005367 mRNA No translation available.
BC030416 mRNA Translation: AAH30416.1 Sequence problems.
CCDSiCCDS40690.1
RefSeqiNP_001074622.1, NM_001081153.1
XP_006510996.1, XM_006510933.3

3D structure databases

SMRiQ8K0T7
ModBaseiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000139027

PTM databases

iPTMnetiQ8K0T7
PhosphoSitePlusiQ8K0T7

Proteomic databases

jPOSTiQ8K0T7
MaxQBiQ8K0T7
PaxDbiQ8K0T7
PeptideAtlasiQ8K0T7
PRIDEiQ8K0T7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000075245; ENSMUSP00000074726; ENSMUSG00000062151
ENSMUST00000184666; ENSMUSP00000139027; ENSMUSG00000062151
GeneIDi208898
KEGGimmu:208898
UCSCiuc033jlk.1 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
440279
MGIiMGI:2149021 Unc13c

Phylogenomic databases

eggNOGiKOG1011 Eukaryota
ENOG410XS5D LUCA
GeneTreeiENSGT00940000155174
HOGENOMiHOG000154775
InParanoidiQ8K0T7
KOiK15293
OMAiMMYRSQS
OrthoDBi117172at2759
PhylomeDBiQ8K0T7
TreeFamiTF312844

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Unc13c mouse

Protein Ontology

More...
PROi
PR:Q8K0T7

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000062151 Expressed in 167 organ(s), highest expression level in cleaving embryo
GenevisibleiQ8K0T7 MM

Family and domain databases

CDDicd00029 C1, 1 hit
cd04027 C2B_Munc13, 1 hit
Gene3Di2.60.40.150, 2 hits
InterProiView protein in InterPro
IPR000008 C2_dom
IPR035892 C2_domain_sf
IPR010439 CAPS_dom
IPR014770 Munc13_1
IPR014772 Munc13_dom-2
IPR019558 Munc13_subgr_dom-2
IPR002219 PE/DAG-bd
IPR027080 Unc-13
IPR037302 Unc-13_C2B
IPR027087 Unc13C
PANTHERiPTHR10480 PTHR10480, 1 hit
PTHR10480:SF2 PTHR10480:SF2, 1 hit
PfamiView protein in Pfam
PF00130 C1_1, 1 hit
PF00168 C2, 2 hits
PF06292 DUF1041, 1 hit
PF10540 Membr_traf_MHD, 1 hit
PRINTSiPR00360 C2DOMAIN
SMARTiView protein in SMART
SM00109 C1, 1 hit
SM00239 C2, 2 hits
SM01145 DUF1041, 1 hit
PROSITEiView protein in PROSITE
PS50004 C2, 2 hits
PS51258 MHD1, 1 hit
PS51259 MHD2, 1 hit
PS00479 ZF_DAG_PE_1, 1 hit
PS50081 ZF_DAG_PE_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiUN13C_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8K0T7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: July 10, 2007
Last modified: September 18, 2019
This is version 146 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again