UniProtKB - Q8K0L9 (ZBT20_MOUSE)

BLAST

>sp|Q8K0L9|ZBT20_MOUSE Zinc finger and BTB domain-containing protein 20 OS=Mus musculus OX=10090 GN=Zbtb20 PE=1 SV=1
MLERKKPKTAENQKASEENEITQPGGSSAKPALPCLNFEAVLSPAPALIHSTHSLTNSHA
HTGSSDCDISCKGMTERIHSINLHNFSNSVLETLNEQRNRGHFCDVTVRIHGSMLRAHRC
VLAAGSPFFQDKLLLGYSDIEIPSVVSVQSVQKLIDFMYSGVLRVSQSEALQILTAASIL
QIKTVIDECTRIVSQNVGDVFPGIQDSGQDTPRGTPESGTSGQSSDTESGYLQSHPQHSV
DRIYSALYACSMQNGSGERSFYSGAVVSHHETALGLPRDHHMEDPSWITRIHERSQQMER
YLSTTPETTHCRKQPRPVRIQTLVGNIHIKQEMEDDYDYYGQQRVQILERNESEECTEDT
DQAEGTESEPKGESFDSGVSSSIGTEPDSVEQQFGAAAPRDGQAEPAQPEQAAEAPAESS
AQPNQLEPGASSPERSNESEMDNTVITVSNSSDKGVLQQPSVNTSIGQPLPSTQLYLRQT
ETLTSNLRMPLTLTSNTQVIGTAGNTYLPALFTTQPAGSGPKPFLFSLPQPLTGQQTQFV
TVSQPGLSTFTAQLPAPQPLASSAGHSTASGQGDKKPYECTLCNKTFTAKQNYVKHMFVH
TGEKPHQCSICWRSFSLKDYLIKHMVTHTGVRAYQCSICNKRFTQKSSLNVHMRLHRGEK
SYECYICKKKFSHKTLLERHVALHSASNGTPPAGTPPGARAGPPGVVACTEGTTYVCSVC
PAKFDQIEQFNDHMRMHVSDG

Align

Format
Add to basket Added to basket
History
Entry version 142 (07 Nov 2018)
Sequence version 1 (01 Oct 2002)
Previous versions | rss
Other tutorials and videos
Help video
Feedback

Protein

Zinc finger and BTB domain-containing protein 20

Gene

Zbtb20

Organism

Mus musculus (Mouse)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

May be a transcription factor that may be involved in hematopoiesis, oncogenesis, and immune responses (By similarity). Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal (PubMed:27446912).By similarity1 Publication

Regions

Feature key	Position(s)	DescriptionActions	Length
Zinc fingerⁱ	578 – 600	C2H2-type 1PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	606 – 628	C2H2-type 2PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	634 – 656	C2H2-type 3PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	662 – 684	C2H2-type 4PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	715 – 737	C2H2-type 5PROSITE-ProRule annotationAdd BLAST	23

GO - Molecular functionⁱ

DNA binding
Source: MGI
Inferred from direct assayⁱ
- 11744704
metal ion binding Source: UniProtKB-KW
proximal promoter DNA-binding transcription repressor activity, RNA polymerase II-specific
Source: MGI
Inferred from direct assayⁱ
- 18669658
transcription regulatory region DNA binding
Source: UniProtKB
Inferred from direct assayⁱ
- 28327662

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

cellular response to glucose stimulus
Source: UniProtKB
Inferred from mutant phenotypeⁱ
- 28327662
lipid homeostasis
Source: UniProtKB
Inferred from mutant phenotypeⁱ
- 28327662
negative regulation of gene expression
Source: CACAO
Inferred from mutant phenotypeⁱ
- 23776228
negative regulation of transcription, DNA-templated
Source: CACAO
Inferred from direct assayⁱ
- 23776228
negative regulation of transcription by RNA polymerase II
Source: MGI
Inferred from mutant phenotypeⁱ
- 18669658
positive regulation of glycolytic process
Source: UniProtKB
Inferred from mutant phenotypeⁱ
- 28327662
positive regulation of interferon-beta production
Source: CACAO
Inferred from direct assayⁱ
- 23776228
positive regulation of interleukin-6 production
Source: CACAO
Inferred from direct assayⁱ
- 23776228
positive regulation of lipid biosynthetic process
Source: UniProtKB
Inferred from mutant phenotypeⁱ
- 28327662
positive regulation of tumor necrosis factor production
Source: CACAO
Inferred from direct assayⁱ
- 23776228

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	DNA-binding
Biological process	Transcription, Transcription regulation
Ligand	Metal-binding, Zinc

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Zinc finger and BTB domain-containing protein 20 Alternative name(s): BTB/POZ domain zinc finger factor HOF Zinc finger protein 288
Gene namesⁱ	Name:Zbtb20 Synonyms:Zfp288
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 16

Organism-specific databases

MGIⁱ	MGI:1929213 Zbtb20

Keywords - Cellular componentⁱ

Nucleus

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000325961	1 – 741	Zinc finger and BTB domain-containing protein 20Add BLAST		741

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Modified residueⁱ	211	PhosphothreonineBy similarity	1
Cross-linkⁱ	330	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternateBy similarity
Cross-linkⁱ	330	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateBy similarity
Modified residueⁱ	353	PhosphoserineCombined sources	1
Modified residueⁱ	357	PhosphothreonineCombined sources	1
Cross-linkⁱ	371	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residueⁱ	690	PhosphothreonineCombined sources	1
Modified residueⁱ	695	PhosphothreonineCombined sources	1
Cross-linkⁱ	723	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity

Post-translational modificationⁱ

Sumoylated with SUMO1.1 Publication

Keywords - PTMⁱ

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

PaxDbⁱ	Q8K0L9
PeptideAtlas More...PeptideAtlasⁱ	Q8K0L9
PRIDEⁱ	Q8K0L9

PTM databases

iPTMnetⁱ	Q8K0L9
PhosphoSitePlusⁱ	Q8K0L9

Expressionⁱ

Tissue specificityⁱ

Specifically expressed in early hippocampal neurons, cerebellar granule cells and gliogenic progenitors as well as in differentiated glia (PubMed:11744704). Expressed in adult and aged myogenic satellite cells (PubMed:27446912).2 Publications

Developmental stageⁱ

Not expressed during development, is induced during establishment of satellite cells and acquisition of quiescence.1 Publication

Gene expression databases

Bgeeⁱ	ENSMUSG00000022708 Expressed in 301 organ(s), highest expression level in rostral migratory stream
CleanExⁱ	MM_ZBTB20
ExpressionAtlasⁱ	Q8K0L9 baseline and differential
Genevisibleⁱ	Q8K0L9 MM

Interactionⁱ

Subunit structureⁱ

Can homodimerize. Binds to DNA.

Protein-protein interaction databases

IntActⁱ	Q8K0L9, 1 interactor
STRINGⁱ	10090.ENSMUSP00000078410

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q8K0L9
SMRⁱ	Q8K0L9
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	104 – 167	BTBPROSITE-ProRule annotationAdd BLAST		64

Zinc finger

Feature key	Position(s)	DescriptionActions	Length
Zinc fingerⁱ	578 – 600	C2H2-type 1PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	606 – 628	C2H2-type 2PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	634 – 656	C2H2-type 3PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	662 – 684	C2H2-type 4PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	715 – 737	C2H2-type 5PROSITE-ProRule annotationAdd BLAST	23

Keywords - Domainⁱ

Repeat, Zinc-finger

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000119063
HOGENOMⁱ	HOG000136747
HOVERGENⁱ	HBG060183
InParanoidⁱ	Q8K0L9
KEGG Orthology (KO) More...KOⁱ	K10501
OMAⁱ	ESTHCRK
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G02AP
PhylomeDBⁱ	Q8K0L9
TreeFamⁱ	TF335684

Family and domain databases

InterProⁱ	View protein in InterPro IPR000210 BTB/POZ_dom IPR011333 SKP1/BTB/POZ_sf IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00651 BTB, 1 hit PF00096 zf-C2H2, 5 hits
SMARTⁱ	View protein in SMART SM00225 BTB, 1 hit SM00355 ZnF_C2H2, 5 hits
SUPFAMⁱ	SSF54695 SSF54695, 1 hit SSF57667 SSF57667, 2 hits
PROSITEⁱ	View protein in PROSITE PS50097 BTB, 1 hit PS00028 ZINC_FINGER_C2H2_1, 5 hits PS50157 ZINC_FINGER_C2H2_2, 5 hits

Sequences (2+)ⁱ

Sequence statusⁱ: Complete.

This entry describes 2 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 2 described isoforms and 5 potential isoforms that are computationally mapped.Show all Align All

Isoform 1 (identifier: Q8K0L9-1) [UniParc]FASTA Add to basket

Also known as: HOF-L

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MLERKKPKTA ENQKASEENE ITQPGGSSAK PALPCLNFEA VLSPAPALIH 
        60         70         80         90        100
STHSLTNSHA HTGSSDCDIS CKGMTERIHS INLHNFSNSV LETLNEQRNR 
       110        120        130        140        150
GHFCDVTVRI HGSMLRAHRC VLAAGSPFFQ DKLLLGYSDI EIPSVVSVQS 
       160        170        180        190        200
VQKLIDFMYS GVLRVSQSEA LQILTAASIL QIKTVIDECT RIVSQNVGDV 
       210        220        230        240        250
FPGIQDSGQD TPRGTPESGT SGQSSDTESG YLQSHPQHSV DRIYSALYAC 
       260        270        280        290        300
SMQNGSGERS FYSGAVVSHH ETALGLPRDH HMEDPSWITR IHERSQQMER 
       310        320        330        340        350
YLSTTPETTH CRKQPRPVRI QTLVGNIHIK QEMEDDYDYY GQQRVQILER 
       360        370        380        390        400
NESEECTEDT DQAEGTESEP KGESFDSGVS SSIGTEPDSV EQQFGAAAPR 
       410        420        430        440        450
DGQAEPAQPE QAAEAPAESS AQPNQLEPGA SSPERSNESE MDNTVITVSN 
       460        470        480        490        500
SSDKGVLQQP SVNTSIGQPL PSTQLYLRQT ETLTSNLRMP LTLTSNTQVI 
       510        520        530        540        550
GTAGNTYLPA LFTTQPAGSG PKPFLFSLPQ PLTGQQTQFV TVSQPGLSTF 
       560        570        580        590        600
TAQLPAPQPL ASSAGHSTAS GQGDKKPYEC TLCNKTFTAK QNYVKHMFVH 
       610        620        630        640        650
TGEKPHQCSI CWRSFSLKDY LIKHMVTHTG VRAYQCSICN KRFTQKSSLN 
       660        670        680        690        700
VHMRLHRGEK SYECYICKKK FSHKTLLERH VALHSASNGT PPAGTPPGAR 
       710        720        730        740 
AGPPGVVACT EGTTYVCSVC PAKFDQIEQF NDHMRMHVSD G

Length:741

Mass (Da):81,034

Last modified:October 1, 2002 - v1

Checksum:ⁱ04C0744D66BFE418

Isoform 2 (identifier: Q8K0L9-2) [UniParc]FASTA Add to basket

Also known as: HOF-S

The sequence of this isoform differs from the canonical sequence as follows:
1-73: Missing.

« Hide

        10         20         30         40         50
MTERIHSINL HNFSNSVLET LNEQRNRGHF CDVTVRIHGS MLRAHRCVLA 
        60         70         80         90        100
AGSPFFQDKL LLGYSDIEIP SVVSVQSVQK LIDFMYSGVL RVSQSEALQI 
       110        120        130        140        150
LTAASILQIK TVIDECTRIV SQNVGDVFPG IQDSGQDTPR GTPESGTSGQ 
       160        170        180        190        200
SSDTESGYLQ SHPQHSVDRI YSALYACSMQ NGSGERSFYS GAVVSHHETA 
       210        220        230        240        250
LGLPRDHHME DPSWITRIHE RSQQMERYLS TTPETTHCRK QPRPVRIQTL 
       260        270        280        290        300
VGNIHIKQEM EDDYDYYGQQ RVQILERNES EECTEDTDQA EGTESEPKGE 
       310        320        330        340        350
SFDSGVSSSI GTEPDSVEQQ FGAAAPRDGQ AEPAQPEQAA EAPAESSAQP 
       360        370        380        390        400
NQLEPGASSP ERSNESEMDN TVITVSNSSD KGVLQQPSVN TSIGQPLPST 
       410        420        430        440        450
QLYLRQTETL TSNLRMPLTL TSNTQVIGTA GNTYLPALFT TQPAGSGPKP 
       460        470        480        490        500
FLFSLPQPLT GQQTQFVTVS QPGLSTFTAQ LPAPQPLASS AGHSTASGQG 
       510        520        530        540        550
DKKPYECTLC NKTFTAKQNY VKHMFVHTGE KPHQCSICWR SFSLKDYLIK 
       560        570        580        590        600
HMVTHTGVRA YQCSICNKRF TQKSSLNVHM RLHRGEKSYE CYICKKKFSH 
       610        620        630        640        650
KTLLERHVAL HSASNGTPPA GTPPGARAGP PGVVACTEGT TYVCSVCPAK 
       660 
FDQIEQFNDH MRMHVSDG

Show »

Length:668

Mass (Da):73,382

Checksum:ⁱ5A6FF5BEEA3963A3

Computationally mapped potential isoform sequencesⁱ

There are 5 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

E0CXK1	E0CXK1_MOUSE	Zinc finger and BTB domain-containi... Zinc finger and BTB domain-containing protein 20	Zbtb20	75	Annotation score:
E0CYJ9	E0CYJ9_MOUSE	Zinc finger and BTB domain-containi... Zinc finger and BTB domain-containing protein 20	Zbtb20	131	Annotation score:
E0CYH3	E0CYH3_MOUSE	Zinc finger and BTB domain-containi... Zinc finger and BTB domain-containing protein 20	Zbtb20	138	Annotation score:
E0CXT9	E0CXT9_MOUSE	Zinc finger and BTB domain-containi... Zinc finger and BTB domain-containing protein 20	Zbtb20	60	Annotation score:
E0CX28	E0CX28_MOUSE	Zinc finger and BTB domain-containi... Zinc finger and BTB domain-containing protein 20	Zbtb20	63	Annotation score:

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	88	N → D in BAB23755 (PubMed:16141072).Curated		1
Sequence conflictⁱ	421	A → D in AAF06015 (PubMed:11744704).Curated		1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_032504	1 – 73	Missing in isoform 2. 2 PublicationsAdd BLAST		73

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF194030 mRNA Translation: AAF06015.1 AK005028 mRNA Translation: BAB23755.1 CT010512 Genomic DNA No translation available. BC031114 mRNA Translation: AAH31114.1 BC056446 mRNA Translation: AAH56446.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS28178.1 [Q8K0L9-1] CCDS49851.1 [Q8K0L9-2]
NCBI Reference Sequences More...RefSeqⁱ	NP_001272734.1, NM_001285805.1 [Q8K0L9-1] NP_062752.2, NM_019778.2 [Q8K0L9-1] NP_851401.1, NM_181058.1 [Q8K0L9-2] XP_006522475.1, XM_006522412.3 [Q8K0L9-1] XP_006522476.1, XM_006522413.3 [Q8K0L9-1] XP_006522477.1, XM_006522414.2 [Q8K0L9-1] XP_006522478.1, XM_006522415.3 [Q8K0L9-1] XP_006522479.1, XM_006522416.3 [Q8K0L9-1] XP_006522481.1, XM_006522418.3 [Q8K0L9-1] XP_006522485.1, XM_006522422.3 [Q8K0L9-2] XP_006522487.1, XM_006522424.3 [Q8K0L9-2] XP_011244291.1, XM_011245989.2 [Q8K0L9-1] XP_011244292.1, XM_011245990.2 [Q8K0L9-1] XP_017172580.1, XM_017317091.1 [Q8K0L9-1] XP_017172581.1, XM_017317092.1 [Q8K0L9-1] XP_017172582.1, XM_017317093.1 [Q8K0L9-1] XP_017172583.1, XM_017317094.1 [Q8K0L9-1] XP_017172584.1, XM_017317095.1 [Q8K0L9-1] XP_017172585.1, XM_017317096.1 [Q8K0L9-1] XP_017172586.1, XM_017317097.1 [Q8K0L9-1] XP_017172587.1, XM_017317098.1 [Q8K0L9-1] XP_017172588.1, XM_017317099.1 [Q8K0L9-2] XP_017172589.1, XM_017317100.1 [Q8K0L9-2] XP_017172590.1, XM_017317101.1 [Q8K0L9-2] XP_017172591.1, XM_017317102.1 [Q8K0L9-2] XP_017172592.1, XM_017317103.1 [Q8K0L9-2] XP_017172593.1, XM_017317104.1 [Q8K0L9-2] XP_017172594.1, XM_017317105.1 [Q8K0L9-2]
UniGeneⁱ	Mm.136238 Mm.441121 Mm.441972 Mm.460947 Mm.487184 Mm.491236

Genome annotation databases

Keywords - Coding sequence diversityⁱ

Alternative splicing

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q8K0L9	Zinc finger and BTB domain-containing protein 20 (Fragment)		MOUSE		131	UniRef100_Q8K0L9
Q8K0L9-2	Zinc finger and BTB domain-containing protein 20 (Fragment)		MOUSE		63	UniRef100_Q8K0L9-2
UPI0001547ED4		MOUSE		746

Protein	Similar proteins		Species	Score	Length	Source
Q8K0L9	Zinc finger and BTB domain-containing protein 20 (Fragment)		MOUSE		131	UniRef90_Q8K0L9
Zinc finger and BTB domain-containing protein 20		FUKDA		767
Uncharacterized protein		MACMU		755
Uncharacterized protein		CERAT		668
Uncharacterized protein		CHLSB		668
+78

Protein	Similar proteins		Species	Score	Length	Source
Q8K0L9	Zinc finger and BTB domain-containing protein 20		HUMAN		741	UniRef50_Q8K0L9
Zinc finger and BTB domain-containing protein 20 (Fragment)		MOUSE		131
Zinc finger and BTB domain-containing protein 20		FUKDA		767
Uncharacterized protein		MACMU		755
Uncharacterized protein		CERAT		668
+368

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF194030 mRNA Translation: AAF06015.1 AK005028 mRNA Translation: BAB23755.1 CT010512 Genomic DNA No translation available. BC031114 mRNA Translation: AAH31114.1 BC056446 mRNA Translation: AAH56446.1
CCDSⁱ	CCDS28178.1 [Q8K0L9-1] CCDS49851.1 [Q8K0L9-2]
RefSeqⁱ	NP_001272734.1, NM_001285805.1 [Q8K0L9-1] NP_062752.2, NM_019778.2 [Q8K0L9-1] NP_851401.1, NM_181058.1 [Q8K0L9-2] XP_006522475.1, XM_006522412.3 [Q8K0L9-1] XP_006522476.1, XM_006522413.3 [Q8K0L9-1] XP_006522477.1, XM_006522414.2 [Q8K0L9-1] XP_006522478.1, XM_006522415.3 [Q8K0L9-1] XP_006522479.1, XM_006522416.3 [Q8K0L9-1] XP_006522481.1, XM_006522418.3 [Q8K0L9-1] XP_006522485.1, XM_006522422.3 [Q8K0L9-2] XP_006522487.1, XM_006522424.3 [Q8K0L9-2] XP_011244291.1, XM_011245989.2 [Q8K0L9-1] XP_011244292.1, XM_011245990.2 [Q8K0L9-1] XP_017172580.1, XM_017317091.1 [Q8K0L9-1] XP_017172581.1, XM_017317092.1 [Q8K0L9-1] XP_017172582.1, XM_017317093.1 [Q8K0L9-1] XP_017172583.1, XM_017317094.1 [Q8K0L9-1] XP_017172584.1, XM_017317095.1 [Q8K0L9-1] XP_017172585.1, XM_017317096.1 [Q8K0L9-1] XP_017172586.1, XM_017317097.1 [Q8K0L9-1] XP_017172587.1, XM_017317098.1 [Q8K0L9-1] XP_017172588.1, XM_017317099.1 [Q8K0L9-2] XP_017172589.1, XM_017317100.1 [Q8K0L9-2] XP_017172590.1, XM_017317101.1 [Q8K0L9-2] XP_017172591.1, XM_017317102.1 [Q8K0L9-2] XP_017172592.1, XM_017317103.1 [Q8K0L9-2] XP_017172593.1, XM_017317104.1 [Q8K0L9-2] XP_017172594.1, XM_017317105.1 [Q8K0L9-2]
UniGeneⁱ	Mm.136238 Mm.441121 Mm.441972 Mm.460947 Mm.487184 Mm.491236

3D structure databases

ProteinModelPortalⁱ	Q8K0L9
SMRⁱ	Q8K0L9
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

IntActⁱ	Q8K0L9, 1 interactor
STRINGⁱ	10090.ENSMUSP00000078410

PTM databases

iPTMnetⁱ	Q8K0L9
PhosphoSitePlusⁱ	Q8K0L9

Proteomic databases

PaxDbⁱ	Q8K0L9
PeptideAtlasⁱ	Q8K0L9
PRIDEⁱ	Q8K0L9

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000079441; ENSMUSP00000078410; ENSMUSG00000022708 [Q8K0L9-1] ENSMUST00000114690; ENSMUSP00000110338; ENSMUSG00000022708 [Q8K0L9-2] ENSMUST00000114691; ENSMUSP00000110339; ENSMUSG00000022708 [Q8K0L9-2] ENSMUST00000114694; ENSMUSP00000110342; ENSMUSG00000022708 [Q8K0L9-1] ENSMUST00000114695; ENSMUSP00000110343; ENSMUSG00000022708 [Q8K0L9-1]
GeneIDⁱ	56490
KEGGⁱ	mmu:56490
UCSCⁱ	uc007zga.3 mouse [Q8K0L9-1]

Organism-specific databases

CTDⁱ	26137
MGIⁱ	MGI:1929213 Zbtb20

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
GeneTreeⁱ	ENSGT00760000119063
HOGENOMⁱ	HOG000136747
HOVERGENⁱ	HBG060183
InParanoidⁱ	Q8K0L9
KOⁱ	K10501
OMAⁱ	ESTHCRK
OrthoDBⁱ	EOG091G02AP
PhylomeDBⁱ	Q8K0L9
TreeFamⁱ	TF335684

Miscellaneous databases

ChiTaRSⁱ	Zbtb20 mouse
Protein Ontology More...PROⁱ	PR:Q8K0L9
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000022708 Expressed in 301 organ(s), highest expression level in rostral migratory stream
CleanExⁱ	MM_ZBTB20
ExpressionAtlasⁱ	Q8K0L9 baseline and differential
Genevisibleⁱ	Q8K0L9 MM

Family and domain databases

InterProⁱ	View protein in InterPro IPR000210 BTB/POZ_dom IPR011333 SKP1/BTB/POZ_sf IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
Pfamⁱ	View protein in Pfam PF00651 BTB, 1 hit PF00096 zf-C2H2, 5 hits
SMARTⁱ	View protein in SMART SM00225 BTB, 1 hit SM00355 ZnF_C2H2, 5 hits
SUPFAMⁱ	SSF54695 SSF54695, 1 hit SSF57667 SSF57667, 2 hits
PROSITEⁱ	View protein in PROSITE PS50097 BTB, 1 hit PS00028 ZINC_FINGER_C2H2_1, 5 hits PS50157 ZINC_FINGER_C2H2_2, 5 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	ZBT20_MOUSE
Accessionⁱ	Q8K0L9Primary (citable) accession number: Q8K0L9 Secondary accession number(s): A6X916, Q9DBD4, Q9QZ87
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	March 18, 2008
	Last sequence update:	October 1, 2002
	Last modified:	November 7, 2018
	This is version 142 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q8K0L9 (ZBT20_MOUSE)

Your basket is currently empty. i <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.<p><a href='/help/basket' target='_top'>More...</a></p>

Zinc finger and BTB domain-containing protein 20

Zbtb20

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Nucleus

Other locations

Keywords - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Zinc finger

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Experimental Info

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

UniProt is an ELIXIR core data resource

Your basket is currently empty. ⁱ

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ