UniProtKB - Q8K094 (Q8K094_MOUSE)
Protein
Submitted name:
Poliovirus receptor
Gene
Pvr
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- dynein light chain binding Source: MGI
- virus receptor activity Source: MGI
GO - Biological processi
- cell-cell adhesion Source: MGI
- cell migration Source: MGI
- heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules Source: GO_Central
- homophilic cell adhesion via plasma membrane adhesion molecules Source: GO_Central
Keywordsi
Molecular function | ReceptorImported |
Enzyme and pathway databases
Reactomei | R-MMU-198933, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-MMU-420597, Nectin/Necl trans heterodimerization |
Names & Taxonomyi
Protein namesi | Submitted name: Poliovirus receptorImportedSubmitted name: Tage4 receptorImported |
Gene namesi | |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:107741, Pvr |
Subcellular locationi
Plasma Membrane
- plasma membrane Source: MGI
Other locations
- adherens junction Source: GO_Central
- cell surface Source: MGI
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 348 – 370 | HelicalSequence analysisAdd BLAST | 23 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 28 | Sequence analysisAdd BLAST | 28 | |
ChainiPRO_5015099251 | 29 – 408 | Sequence analysisAdd BLAST | 380 |
Proteomic databases
ProteomicsDBi | 338513 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000040511, Expressed in decidua and 269 other tissues |
Interactioni
GO - Molecular functioni
- dynein light chain binding Source: MGI
Protein-protein interaction databases
STRINGi | 10090.ENSMUSP00000039205 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 43 – 140 | Ig-likeInterPro annotationAdd BLAST | 98 | |
Domaini | 145 – 237 | Ig-likeInterPro annotationAdd BLAST | 93 | |
Domaini | 244 – 332 | Ig-likeInterPro annotationAdd BLAST | 89 |
Keywords - Domaini
SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
eggNOGi | ENOG502QWSY, Eukaryota |
GeneTreei | ENSGT00940000162848 |
HOGENOMi | CLU_029618_0_0_1 |
OMAi | YECQIAT |
OrthoDBi | 1087343at2759 |
TreeFami | TF331051 |
Family and domain databases
Gene3Di | 2.60.40.10, 3 hits |
InterProi | View protein in InterPro IPR013162, CD80_C2-set IPR007110, Ig-like_dom IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR003599, Ig_sub IPR013106, Ig_V-set |
Pfami | View protein in Pfam PF08205, C2-set_2, 1 hit PF07686, V-set, 1 hit |
SMARTi | View protein in SMART SM00409, IG, 2 hits SM00406, IGv, 1 hit |
SUPFAMi | SSF48726, SSF48726, 3 hits |
PROSITEi | View protein in PROSITE PS50835, IG_LIKE, 3 hits |
i Sequence
Sequence statusi: Complete.
Q8K094-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAQLARATRS PLSWLLLLFC YALRKAGGDI RVLVPYNSTG VLGGSTTLHC
60 70 80 90 100
SLTSNENVTI TQITWMKKDS GGSHALVAVF HPKKGPNIKE PERVKFLAAQ
110 120 130 140 150
QDLRNASLAI SNLSVEDEGI YECQIATFPR GSRSTNAWLK VQARPKNTAE
160 170 180 190 200
ALEPSPTLIL QDVAKCISAN GHPPGRISWP SNVNGSHREM KEPGSQPGTT
210 220 230 240 250
TVTSYLSMVP SRQADGKNIT CTVEHESLQE LDQLLVTLSQ PYPPENVSIS
260 270 280 290 300
GYDGNWYVGL TNLTLTCEAH SKPAPDMAGY NWSTNTGDFP NSVKRQGNML
310 320 330 340 350
LISTVEDGLN NTVIVCEVTN ALGSGQGQVH IIVKEKPENM QQNTRLHLGY
360 370 380 390 400
IFLIVFVLAV VIIIAALYTI RRCRHGRALQ SNPSERENVQ YSSVNGDCRL
NMEPNSTR
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC149085 Genomic DNA No translation available. BC032283 mRNA Translation: AAH32283.1 BC138219 mRNA Translation: AAI38220.1 BC138220 mRNA Translation: AAI38221.1 AK038747 mRNA Translation: BAC30124.1 AK080753 mRNA Translation: BAC38008.1 AK165873 mRNA Translation: BAE38429.1 AJ563420 mRNA Translation: CAD91411.1 |
RefSeqi | NP_081790.1, NM_027514.2 |
Genome annotation databases
Ensembli | ENSMUST00000043517; ENSMUSP00000039205; ENSMUSG00000040511 |
GeneIDi | 52118 |
KEGGi | mmu:52118 |
UCSCi | uc009fno.2, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC149085 Genomic DNA No translation available. BC032283 mRNA Translation: AAH32283.1 BC138219 mRNA Translation: AAI38220.1 BC138220 mRNA Translation: AAI38221.1 AK038747 mRNA Translation: BAC30124.1 AK080753 mRNA Translation: BAC38008.1 AK165873 mRNA Translation: BAE38429.1 AJ563420 mRNA Translation: CAD91411.1 |
RefSeqi | NP_081790.1, NM_027514.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 10090.ENSMUSP00000039205 |
Proteomic databases
ProteomicsDBi | 338513 |
Protocols and materials databases
Antibodypediai | 2235, 689 antibodies |
DNASUi | 52118 |
Genome annotation databases
Ensembli | ENSMUST00000043517; ENSMUSP00000039205; ENSMUSG00000040511 |
GeneIDi | 52118 |
KEGGi | mmu:52118 |
UCSCi | uc009fno.2, mouse |
Organism-specific databases
CTDi | 5817 |
MGIi | MGI:107741, Pvr |
Phylogenomic databases
eggNOGi | ENOG502QWSY, Eukaryota |
GeneTreei | ENSGT00940000162848 |
HOGENOMi | CLU_029618_0_0_1 |
OMAi | YECQIAT |
OrthoDBi | 1087343at2759 |
TreeFami | TF331051 |
Enzyme and pathway databases
Reactomei | R-MMU-198933, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-MMU-420597, Nectin/Necl trans heterodimerization |
Miscellaneous databases
BioGRID-ORCSi | 52118, 1 hit in 53 CRISPR screens |
ChiTaRSi | Pvr, mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000040511, Expressed in decidua and 269 other tissues |
Family and domain databases
Gene3Di | 2.60.40.10, 3 hits |
InterProi | View protein in InterPro IPR013162, CD80_C2-set IPR007110, Ig-like_dom IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR003599, Ig_sub IPR013106, Ig_V-set |
Pfami | View protein in Pfam PF08205, C2-set_2, 1 hit PF07686, V-set, 1 hit |
SMARTi | View protein in SMART SM00409, IG, 2 hits SM00406, IGv, 1 hit |
SUPFAMi | SSF48726, SSF48726, 3 hits |
PROSITEi | View protein in PROSITE PS50835, IG_LIKE, 3 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q8K094_MOUSE | |
Accessioni | Q8K094Primary (citable) accession number: Q8K094 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 1, 2002 |
Last sequence update: | October 1, 2002 | |
Last modified: | April 7, 2021 | |
This is version 180 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |