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Entry version 133 (29 Sep 2021)
Sequence version 1 (01 Oct 2002)
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Protein

Spermatogenesis-associated protein 2

Gene

Spata2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Bridging factor that mediates the recruitment of CYLD to the LUBAC complex, thereby regulating TNF-alpha-induced necroptosis (By similarity).

Acts as a direct binding intermediate that bridges RNF31/HOIP, the catalytic subunit of the LUBAC complex, and the deubiquitinase (CYLD), thereby recruiting CYLD to the TNF-R1 signaling complex (TNF-RSC) (By similarity).

Required to activate the 'Met-1'- (linear) and 'Lys-63'-linked deubiquitinase activities of CYLD (PubMed:28701375).

Controls the kinase activity of RIPK1 and TNF-alpha-induced necroptosis by promoting 'Met-1'-linked deubiquitination of RIPK1 by CYLD (PubMed:28701375).

By similarity1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processNecrosis

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Spermatogenesis-associated protein 22 Publications
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Spata22 PublicationsImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2146885, Spata2

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSMUSG00000047030

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Mice are fertile and healthy with no obvious abnormalities in major organs in normal conditions (PubMed:29025062, PubMed:28701375). Males however display a decreased fertility: they show reduced testis size and sperm number (PubMed:29025062). The proliferation of germ cells in the seminiferous tubules is decreased in male gonads (PubMed:29025062). Impaired necroptosis: deficient cells show resistance to RIPK1-dependent apoptosis and necroptosis and are partially protected against RIPK1-independent apoptosis (PubMed:28701375).2 Publications

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004455741 – 515Spermatogenesis-associated protein 2Add BLAST515

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8K004

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8K004

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8K004

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8K004

PRoteomics IDEntifications database

More...
PRIDEi
Q8K004

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
334874 [Q8K004-1]
343391

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8K004

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8K004

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Widely expressed, with highest expression in testis, lung and intestine, and lower expression in brain, heart and spleen (PubMed:28701375). Present at high level in Sertoli cells: expressed from stage I to stage XII of the testis seminiferous epithelium (at protein level) (PubMed:29025062).2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000047030, Expressed in ear vesicle and 262 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts (via the PIM motif) with RNF31/HOIP (via the PUB domain); the interaction is direct.

Interacts (via the PUB domain) with CYLD; the interaction is direct.

By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000057095

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8K004, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8K004

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini78 – 150PUBSequence analysisAdd BLAST73

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni429 – 452DisorderedSequence analysisAdd BLAST24

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi321 – 338PIM motifBy similarityAdd BLAST18

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SPATA2 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502RR2T, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00530000063956

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_039585_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8K004

Identification of Orthologs from Complete Genome Data

More...
OMAi
YDPCCRK

Database of Orthologous Groups

More...
OrthoDBi
461395at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8K004

TreeFam database of animal gene trees

More...
TreeFami
TF328840

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR029744, SPATA2

The PANTHER Classification System

More...
PANTHERi
PTHR15326:SF8, PTHR15326:SF8, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q8K004-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MDTKYKDDLF RKYVQFHEGK VDTTPGNQQP GSDEYLRVAA ATLLSLHKVD
60 70 80 90 100
PLYRFRLIQF YEVVESSLRS LSSSSLSALH CAFSMLETMA INLFLFPWKK
110 120 130 140 150
EFRSIKTYTG PFVYYVKSTL LEKDIRAILR FMGYEPELGT VYKLKELVES
160 170 180 190 200
LQVKMVSFEL FLAKVECEQM LGIHSQVKDK GYSELDVVAE RKGSTEDARG
210 220 230 240 250
CSDALRRRAE SREHLTTSMA RVALQKSASE RAAKDYYKPR VTKPSRSVDA
260 270 280 290 300
YDSYWESRKP PSKASLSLRK EPLAMDVGED LKDEIIRPSP SLLAMSSSPH
310 320 330 340 350
GSPDDLSSIS SINGLGLLRS TYFSTQDDVD LYTDSEPRAT YRRQDALRPD
360 370 380 390 400
VWLVKNDTHP IYHKRSPPTK ESALSKCQNC GLSCSSSLCQ RCDSVLVCPS
410 420 430 440 450
ASKPSAFPSK ASVHDSLAHG APMREKYVGH QTQGLDRLAP VHSKPKPSTT
460 470 480 490 500
ATSRCGFCNR AGATNTCTQC SKVSCDACLG AYHYDPCCRK SELHKFLPNS
510
QLNYKSAPFS QLVYR
Length:515
Mass (Da):57,812
Last modified:October 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i52968FF8ABA4D206
GO
Isoform 2 (identifier: Q8K004-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     403-414: KPSAFPSKASVH → PLLGVSHYRRSL
     415-515: Missing.

Show »
Length:414
Mass (Da):46,862
Checksum:iE9AD7DB34F01C603
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti501Q → K in BAE42698 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_059905403 – 414KPSAF…KASVH → PLLGVSHYRRSL in isoform 2. Add BLAST12
Alternative sequenceiVSP_059906415 – 515Missing in isoform 2. Add BLAST101

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK051741 mRNA Translation: BAC34748.1
AK144826 mRNA Translation: BAE26086.1
AK156188 mRNA Translation: BAE33617.1
AK162743 mRNA Translation: BAE37046.1
AK170356 mRNA Translation: BAE41742.1
AK171664 mRNA Translation: BAE42596.1
AK171852 mRNA Translation: BAE42698.1
AL589870 Genomic DNA No translation available.
BC034597 mRNA Translation: AAH34597.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS17100.1 [Q8K004-1]
CCDS89587.1 [Q8K004-2]

NCBI Reference Sequences

More...
RefSeqi
NP_739562.1, NM_170756.2 [Q8K004-1]
XP_006499647.1, XM_006499584.2 [Q8K004-1]
XP_006499649.1, XM_006499586.3 [Q8K004-1]
XP_017174138.1, XM_017318649.1 [Q8K004-1]
XP_017174139.1, XM_017318650.1 [Q8K004-1]
XP_017174140.1, XM_017318651.1 [Q8K004-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000057627; ENSMUSP00000057095; ENSMUSG00000047030 [Q8K004-1]
ENSMUST00000109211; ENSMUSP00000104834; ENSMUSG00000047030 [Q8K004-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
263876

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:263876

UCSC genome browser

More...
UCSCi
uc008nzs.1, mouse [Q8K004-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK051741 mRNA Translation: BAC34748.1
AK144826 mRNA Translation: BAE26086.1
AK156188 mRNA Translation: BAE33617.1
AK162743 mRNA Translation: BAE37046.1
AK170356 mRNA Translation: BAE41742.1
AK171664 mRNA Translation: BAE42596.1
AK171852 mRNA Translation: BAE42698.1
AL589870 Genomic DNA No translation available.
BC034597 mRNA Translation: AAH34597.1
CCDSiCCDS17100.1 [Q8K004-1]
CCDS89587.1 [Q8K004-2]
RefSeqiNP_739562.1, NM_170756.2 [Q8K004-1]
XP_006499647.1, XM_006499584.2 [Q8K004-1]
XP_006499649.1, XM_006499586.3 [Q8K004-1]
XP_017174138.1, XM_017318649.1 [Q8K004-1]
XP_017174139.1, XM_017318650.1 [Q8K004-1]
XP_017174140.1, XM_017318651.1 [Q8K004-1]

3D structure databases

SMRiQ8K004
ModBaseiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000057095

PTM databases

iPTMnetiQ8K004
PhosphoSitePlusiQ8K004

Proteomic databases

EPDiQ8K004
jPOSTiQ8K004
MaxQBiQ8K004
PaxDbiQ8K004
PRIDEiQ8K004
ProteomicsDBi334874 [Q8K004-1]
343391

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
28514, 199 antibodies

The DNASU plasmid repository

More...
DNASUi
263876

Genome annotation databases

EnsembliENSMUST00000057627; ENSMUSP00000057095; ENSMUSG00000047030 [Q8K004-1]
ENSMUST00000109211; ENSMUSP00000104834; ENSMUSG00000047030 [Q8K004-2]
GeneIDi263876
KEGGimmu:263876
UCSCiuc008nzs.1, mouse [Q8K004-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
9825
MGIiMGI:2146885, Spata2
VEuPathDBiHostDB:ENSMUSG00000047030

Phylogenomic databases

eggNOGiENOG502RR2T, Eukaryota
GeneTreeiENSGT00530000063956
HOGENOMiCLU_039585_0_0_1
InParanoidiQ8K004
OMAiYDPCCRK
OrthoDBi461395at2759
PhylomeDBiQ8K004
TreeFamiTF328840

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
263876, 6 hits in 62 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Spata2, mouse

Protein Ontology

More...
PROi
PR:Q8K004
RNActiQ8K004, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000047030, Expressed in ear vesicle and 262 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR029744, SPATA2
PANTHERiPTHR15326:SF8, PTHR15326:SF8, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSPAT2_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8K004
Secondary accession number(s): Q3TAH0, Q3UML2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 10, 2018
Last sequence update: October 1, 2002
Last modified: September 29, 2021
This is version 133 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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