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Protein

Proline-rich protein 15-like protein

Gene

Prr15l

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Proline-rich protein 15-like protein
Alternative name(s):
Protein ATAD4
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Prr15l
Synonyms:Atad4
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

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MGIi
MGI:2387599 Prr15l

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002943531 – 100Proline-rich protein 15-like proteinAdd BLAST100

Proteomic databases

MaxQB - The MaxQuant DataBase

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MaxQBi
Q8JZM2

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
Q8JZM2

PeptideAtlas

More...
PeptideAtlasi
Q8JZM2

PRoteomics IDEntifications database

More...
PRIDEi
Q8JZM2

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

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iPTMneti
Q8JZM2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

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PhosphoSitePlusi
Q8JZM2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000047040 Expressed in 92 organ(s), highest expression level in colon

CleanEx database of gene expression profiles

More...
CleanExi
MM_ATAD4

Genevisible search portal to normalized and curated expression data from Genevestigator

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Genevisiblei
Q8JZM2 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000056614

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the PRR15 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
ENOG410J00A Eukaryota
ENOG4112BUZ LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154534

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

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HOGENOMi
HOG000034120

The HOVERGEN Database of Homologous Vertebrate Genes

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HOVERGENi
HBG102089

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
Q8JZM2

Identification of Orthologs from Complete Genome Data

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OMAi
PNLFDDR

Database of Orthologous Groups

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OrthoDBi
EOG091G11H9

Database for complete collections of gene phylogenies

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PhylomeDBi
Q8JZM2

TreeFam database of animal gene trees

More...
TreeFami
TF333189

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR028237 PRR15

The PANTHER Classification System

More...
PANTHERi
PTHR14581 PTHR14581, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15321 ATAD4, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q8JZM2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTEVGWWKLT FLRKKKSTPK VLYEIPDTYA QTEGGAEPPG PDAGDPHSDF
60 70 80 90 100
NSRLEKIVDK NTKGKHVKVS NSGRFKEKKK VRAMLAENPN LFDDRENKGQ
Length:100
Mass (Da):11,359
Last modified:October 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i92335F091133919A
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC39930 differs from that shown. Reason: Erroneous termination at position 101. Translated as stop.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AK077279 mRNA Translation: BAC36726.1
AK087566 mRNA Translation: BAC39930.1 Sequence problems.
AL596384 Genomic DNA No translation available.
BC022765 mRNA Translation: AAH22765.1
BC024510 mRNA Translation: AAH24510.1
BC034192 mRNA Translation: AAH34192.1
BC034213 mRNA Translation: AAH34213.1
BC036171 mRNA Translation: AAH36171.1

The Consensus CDS (CCDS) project

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CCDSi
CCDS25307.1

NCBI Reference Sequences

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RefSeqi
NP_666138.1, NM_146026.1
XP_006533083.1, XM_006533020.3
XP_006533084.1, XM_006533021.3
XP_006533085.1, XM_006533022.3
XP_011247239.1, XM_011248937.2

UniGene gene-oriented nucleotide sequence clusters

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UniGenei
Mm.342551

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000054311; ENSMUSP00000056614; ENSMUSG00000047040
ENSMUST00000062172; ENSMUSP00000056647; ENSMUSG00000047040
ENSMUST00000107633; ENSMUSP00000103259; ENSMUSG00000047040
ENSMUST00000107636; ENSMUSP00000103262; ENSMUSG00000047040

Database of genes from NCBI RefSeq genomes

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GeneIDi
217138

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
mmu:217138

UCSC genome browser

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UCSCi
uc007lcy.1 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK077279 mRNA Translation: BAC36726.1
AK087566 mRNA Translation: BAC39930.1 Sequence problems.
AL596384 Genomic DNA No translation available.
BC022765 mRNA Translation: AAH22765.1
BC024510 mRNA Translation: AAH24510.1
BC034192 mRNA Translation: AAH34192.1
BC034213 mRNA Translation: AAH34213.1
BC036171 mRNA Translation: AAH36171.1
CCDSiCCDS25307.1
RefSeqiNP_666138.1, NM_146026.1
XP_006533083.1, XM_006533020.3
XP_006533084.1, XM_006533021.3
XP_006533085.1, XM_006533022.3
XP_011247239.1, XM_011248937.2
UniGeneiMm.342551

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000056614

PTM databases

iPTMnetiQ8JZM2
PhosphoSitePlusiQ8JZM2

Proteomic databases

MaxQBiQ8JZM2
PaxDbiQ8JZM2
PeptideAtlasiQ8JZM2
PRIDEiQ8JZM2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000054311; ENSMUSP00000056614; ENSMUSG00000047040
ENSMUST00000062172; ENSMUSP00000056647; ENSMUSG00000047040
ENSMUST00000107633; ENSMUSP00000103259; ENSMUSG00000047040
ENSMUST00000107636; ENSMUSP00000103262; ENSMUSG00000047040
GeneIDi217138
KEGGimmu:217138
UCSCiuc007lcy.1 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
79170
MGIiMGI:2387599 Prr15l

Phylogenomic databases

eggNOGiENOG410J00A Eukaryota
ENOG4112BUZ LUCA
GeneTreeiENSGT00940000154534
HOGENOMiHOG000034120
HOVERGENiHBG102089
InParanoidiQ8JZM2
OMAiPNLFDDR
OrthoDBiEOG091G11H9
PhylomeDBiQ8JZM2
TreeFamiTF333189

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Prr15l mouse

Protein Ontology

More...
PROi
PR:Q8JZM2

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000047040 Expressed in 92 organ(s), highest expression level in colon
CleanExiMM_ATAD4
GenevisibleiQ8JZM2 MM

Family and domain databases

InterProiView protein in InterPro
IPR028237 PRR15
PANTHERiPTHR14581 PTHR14581, 1 hit
PfamiView protein in Pfam
PF15321 ATAD4, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPR15L_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8JZM2
Secondary accession number(s): Q8C307
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: October 1, 2002
Last modified: December 5, 2018
This is version 97 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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