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Protein

RNA-directed RNA polymerase

Gene

p1

Organism
Penicillium chrysogenum virus (isolate Caston/2003) (PcV)
Status
Reviewed-Annotation score: -Protein predictedi

Functioni

RNA-dependent RNA polymerase which replicates the viral genome.Curated

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Nucleotidyltransferase, RNA-directed RNA polymerase, Transferase
LigandNucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
RNA-directed RNA polymerase (EC:2.7.7.48)
Gene namesi
Name:p1
OrganismiPenicillium chrysogenum virus (isolate Caston/2003) (PcV)
Taxonomic identifieri654932 [NCBI]
Taxonomic lineageiVirusesdsRNA virusesChrysoviridaeChrysovirus
Virus hostiPenicillium chrysogenum (Penicillium notatum) [TaxID: 5076]
Proteomesi
  • UP000006714 Componenti: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004042681 – 1117RNA-directed RNA polymeraseAdd BLAST1117

Structurei

3D structure databases

ProteinModelPortaliQ8JVC2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

OrthoDBiVOG09000128

Family and domain databases

InterProiView protein in InterPro
IPR001795 RNA-dir_pol_luteovirus
PfamiView protein in Pfam
PF02123 RdRP_4, 1 hit

Sequencei

Sequence statusi: Complete.

Q8JVC2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTVSGRSSWQ NGKTTNAMRA GKLATERDLE SANYGSRSVE KLRHERAVGN
60 70 80 90 100
LNKGRFLGMN KWSDEQLKHS MARYEDLAAT RHNLFAVIMP SGCGKTSLAR
110 120 130 140 150
TYGMVDVDEL VSRAEHDQYV EMRNEIVCGR GDWHDHNTLW FARLNQTLAL
160 170 180 190 200
LDYSVPVVIF VHTEETALEI GARPVACLTL ETTAHEMNIS GRGPKFREFS
210 220 230 240 250
RESLRSCKPS NRVPNQYRFK SNKELEAFFL EVMNVSGLPV GAPFKYSTSI
260 270 280 290 300
WNSSYSRDVP GWILRGERAG TQQVSINELR LLFEQGKIPK ECVDYYVRAS
310 320 330 340 350
YVPTQFDFGV TMFEWSQALG QLPGCYNSRR DFDTLTDLMG VFPPHSPKEV
360 370 380 390 400
TRSNVTLRTL CHTFDILSMP DAKEIASYHV GEGHTLVTNL LANWKGITQF
410 420 430 440 450
TTVSHLVFPW FKVCERDWSD KMKTLHSLVR CSKFFMNTRI TEKDRQALMY
460 470 480 490 500
MDLLVGRGEY TVDEMAEVEL RTDDTYNTKH LSYDPNRQVF TNQQYKKDFI
510 520 530 540 550
TSVEEAYVRL KIEPKPVNVD GFIDFYHRRA SWLTKGGLVY NKLPPEMKKF
560 570 580 590 600
GGQVFDAIYN TCREIQGRHN KKSLFEVYEL AEVLQGANEN NFNLTKTQIK
610 620 630 640 650
YEVGKKDRTL LPGTLVHFVV FTYVLYLAEK QGQIGSVRLN TDSEVDIRYF
660 670 680 690 700
DKKMCTGVFH VLYDWADFNE QHSAWEMGVV VDYLKHLIVA PRDYAVFVEA
710 720 730 740 750
IVAGMYNMGL HDRDGNVHKI WRGLYSGWRG TTWINTVLNF CYVHIALQNV
760 770 780 790 800
ERLFGVRVVL YVDHGGDDID LGLSEPAVMP WFLEVMDAML FKANKWKQMF
810 820 830 840 850
GTRSEFFRNT ICDGRVYASP TRALASFVAG DWEGAGRATV KERVVSLLDQ
860 870 880 890 900
IAKLRRRGCS EELCQGLTIA TISHWCRIKD GEDWLSLPAE IIHGHPDDGG
910 920 930 940 950
LGVPDRDNNF WRLEEKVPEI NEEWYKVVVP DYKASRDYVN VLARDVEKFS
960 970 980 990 1000
LVIEEREKLA RKLSEDSYDI EKSVDHERWK HLLNFRTRVI AKELAVEPME
1010 1020 1030 1040 1050
DSVVFEGFLE YEVEEGTEKK FDLASRYQEF VSYLSLNGRA ITKEELLDLM
1060 1070 1080 1090 1100
SDGEVCLEAI EFQGDIYYAR LVPEFIAYRA TMFCKEAINK GVCDAISAQL
1110
FFRTICWMSA SVFEHAI
Length:1,117
Mass (Da):128,548
Last modified:October 1, 2002 - v1
Checksum:i0A59F9B85F5943B3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF296439 Genomic RNA Translation: AAM95601.1
RefSeqiYP_392482.1, NC_007539.1

Genome annotation databases

GeneIDi5075912
KEGGivg:5075912

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF296439 Genomic RNA Translation: AAM95601.1
RefSeqiYP_392482.1, NC_007539.1

3D structure databases

ProteinModelPortaliQ8JVC2
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi5075912
KEGGivg:5075912

Phylogenomic databases

OrthoDBiVOG09000128

Family and domain databases

InterProiView protein in InterPro
IPR001795 RNA-dir_pol_luteovirus
PfamiView protein in Pfam
PF02123 RdRP_4, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiRDRP_PCVC
AccessioniPrimary (citable) accession number: Q8JVC2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 8, 2011
Last sequence update: October 1, 2002
Last modified: March 15, 2017
This is version 45 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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