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Protein

Early E1A protein

Gene

E1A

Organism
Human adenovirus B serotype 3 (HAdV-3) (Human adenovirus 3)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivatorUniRule annotation
Biological processHost-virus interaction, Transcription, Transcription regulationUniRule annotation, Viral immunoevasionUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Early E1A proteinUniRule annotation
Gene namesi
Name:E1AImported
OrganismiHuman adenovirus B serotype 3 (HAdV-3) (Human adenovirus 3)Imported
Taxonomic identifieri45659 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageAdenoviridaeMastadenovirusHuman mastadenovirus B
Virus hostiHomo sapiens (Human) [TaxID: 9606]
Proteomesi
  • UP000113319 Componenti: Genome
  • UP000108010 Componenti: Genome

Interactioni

Protein-protein interaction databases

IntActiQ8JSK4, 4 interactors
MINTiQ8JSK4

Family & Domainsi

Sequence similaritiesi

Belongs to the adenoviridae E1A protein family.UniRule annotation

Family and domain databases

InterProiView protein in InterPro
IPR014410 Aden_E1A
PfamiView protein in Pfam
PF02703 Adeno_E1A, 1 hit
PIRSFiPIRSF003669 Aden_E1A, 1 hit

Sequencei

Sequence statusi: Complete.

Q8JSK4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRHLRFLPQE VISSETGIEI LEFVVNTLMG DDPEPPVQPF DPPTLHDLYD
60 70 80 90 100
LEIDGPEDPN EEAVNGFFTD SMLLAADEGL DINPPPETLV TPGVVVESGI
110 120 130 140 150
GGKKLPDLGA AEMDLRCYEE GFPPSDDEDG ETEQSIHTAV NEGVKAASDV
160 170 180 190 200
FKLDCPELPG HGCKSCEFHR NNTGMKELLC SLCYMRMHCH FIYSPVSDDE
210 220 230 240 250
SPSPDSTTSP PEIQAPAPAN VCKPIPVKPK PGKRPAVDKL EDLLEGGDGP
260
LDLSTRKLPR Q
Length:261
Mass (Da):28,414
Last modified:October 1, 2002 - v1
Checksum:iBDBEEF2E4E7BACA4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF492352 Genomic DNA Translation: AAM46821.1
AY599834 Genomic DNA Translation: AAW33150.1
DQ086466 Genomic DNA Translation: ABB17767.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF492352 Genomic DNA Translation: AAM46821.1
AY599834 Genomic DNA Translation: AAW33150.1
DQ086466 Genomic DNA Translation: ABB17767.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ8JSK4, 4 interactors
MINTiQ8JSK4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiView protein in InterPro
IPR014410 Aden_E1A
PfamiView protein in Pfam
PF02703 Adeno_E1A, 1 hit
PIRSFiPIRSF003669 Aden_E1A, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ8JSK4_ADE03
AccessioniPrimary (citable) accession number: Q8JSK4
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: November 7, 2018
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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