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Protein

T-complex protein 1 subunit gamma

Gene

cct3

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.SAAS annotation

GO - Molecular functioni

GO - Biological processi

  • embryonic eye morphogenesis Source: ZFIN
  • negative regulation of retinal cell programmed cell death Source: ZFIN
  • protein folding Source: InterPro

Keywordsi

Molecular functionChaperoneUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
T-complex protein 1 subunit gammaUniRule annotation
Gene namesi
Name:cct3Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-020419-5 cct3

Subcellular locationi

Keywords - Cellular componenti

CytoplasmSAAS annotation

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliQ8JHI7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TCP-1 chaperonin family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0364 Eukaryota
COG0459 LUCA
HOVERGENiHBG104982
KOiK09495
PhylomeDBiQ8JHI7

Family and domain databases

CDDicd03337 TCP1_gamma, 1 hit
Gene3Di1.10.560.10, 2 hits
3.30.260.10, 2 hits
3.50.7.10, 1 hit
InterProiView protein in InterPro
IPR012719 Chap_CCT_gamma
IPR017998 Chaperone_TCP-1
IPR002194 Chaperonin_TCP-1_CS
IPR002423 Cpn60/TCP-1
IPR027409 GroEL-like_apical_dom_sf
IPR027413 GROEL-like_equatorial_sf
IPR027410 TCP-1-like_intermed_sf
PfamiView protein in Pfam
PF00118 Cpn60_TCP1, 1 hit
PRINTSiPR00304 TCOMPLEXTCP1
SUPFAMiSSF48592 SSF48592, 2 hits
SSF52029 SSF52029, 1 hit
SSF54849 SSF54849, 2 hits
TIGRFAMsiTIGR02344 chap_CCT_gamma, 1 hit
PROSITEiView protein in PROSITE
PS00750 TCP1_1, 1 hit
PS00751 TCP1_2, 1 hit
PS00995 TCP1_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q8JHI7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMGRPVLVLS QNIKRESGRK VQIGNISAAK TIADIIRTCL GPRAMMKMLL
60 70 80 90 100
DPMGGIVMTN DGNAILREIQ VQHPAAKSMI EISRTQDEEV GDGTTSVIIL
110 120 130 140 150
AGEMLSVAEQ FLEQQMHPTV VIGAYRQALD DMLNILKDIS TPVDVSNRDM
160 170 180 190 200
MLKIINSAIN TKALSRWSTL ACNIALDAVR TVELDENGRE EIDIKKYAKV
210 220 230 240 250
EKVPGGIIED SCVLRGVMVN KDVTHPRMRR LIKNPRIVLL DCSLEYKKGE
260 270 280 290 300
SQTDIEIARE EDFARILQME EEYVQQICED IIRLKPDLIF TEKGISDLAQ
310 320 330 340 350
HYLMKANITA IRRIRKTDNN RIARACGARI ASRTDELTEN DVGTGTGLFE
360 370 380 390 400
VKKIGDEYFT FVTECKDPKA CTILLRGASK EILAEVERNL QDAMQVCRNV
410 420 430 440 450
LLDPYLLPGG GAVEMEVSHR LTERSRAMTG VEQWPYRAVA QALEVVPRTL
460 470 480 490 500
IQNCGASAIR VLTSLRAKHT QEGNSSWGVN GETGTLADME QLGIWEPLAV
510 520 530 540
KAQTYKTAVE TAILLLRIDD IVSGHKKKGD GEQTGGAPME DRE
Length:543
Mass (Da):60,299
Last modified:October 1, 2002 - v1
Checksum:i9465E5BA46DFCF3B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF506209 mRNA Translation: AAM34653.1
RefSeqiNP_775357.1, NM_173250.1
UniGeneiDr.26749

Genome annotation databases

GeneIDi192327
KEGGidre:192327

Similar proteinsi

Entry informationi

Entry nameiQ8JHI7_DANRE
AccessioniPrimary (citable) accession number: Q8JHI7
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: May 23, 2018
This is version 117 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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