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Entry version 118 (07 Oct 2020)
Sequence version 1 (01 Oct 2002)
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Protein

Thrombospondin-4-B

Gene

thbs4b

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions and may be involved in various processes including cellular proliferation, migration, adhesion and attachment. May play a role in ER stress response (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • calcium ion binding Source: InterPro
  • growth factor activity Source: UniProtKB-KW
  • heparin binding Source: UniProtKB

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGrowth factor, Mitogen
Biological processCell adhesion, Unfolded protein response
LigandCalcium

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DRE-186797, Signaling by PDGF
R-DRE-216083, Integrin cell surface interactions
R-DRE-3000178, ECM proteoglycans

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Thrombospondin-4-B
Short name:
Thbs4-B
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:thbs4b
Synonyms:thbs4, tsp4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7955 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesDanionidaeDanioninaeDanio
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000437 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

Organism-specific databases

Zebrafish Information Network genome database

More...
ZFINi
ZDB-GENE-020708-4, thbs4b

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Endoplasmic reticulum, Extracellular matrix, Sarcoplasmic reticulum, Secreted

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 22Sequence analysisAdd BLAST22
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000003585523 – 949Thrombospondin-4-BAdd BLAST927

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi261InterchainPROSITE-ProRule annotationBy similarity
Disulfide bondi264InterchainPROSITE-ProRule annotationBy similarity
Disulfide bondi276 ↔ 287PROSITE-ProRule annotationBy similarity
Disulfide bondi281 ↔ 296PROSITE-ProRule annotationBy similarity
Disulfide bondi299 ↔ 310PROSITE-ProRule annotationBy similarity
Disulfide bondi316 ↔ 327PROSITE-ProRule annotationBy similarity
Disulfide bondi321 ↔ 336PROSITE-ProRule annotationBy similarity
Disulfide bondi339 ↔ 363PROSITE-ProRule annotationBy similarity
Disulfide bondi369 ↔ 383PROSITE-ProRule annotationBy similarity
Disulfide bondi377 ↔ 392PROSITE-ProRule annotationBy similarity
Disulfide bondi395 ↔ 407PROSITE-ProRule annotationBy similarity
Disulfide bondi413 ↔ 427PROSITE-ProRule annotationBy similarity
Disulfide bondi421 ↔ 437PROSITE-ProRule annotationBy similarity
Disulfide bondi439 ↔ 450PROSITE-ProRule annotationBy similarity
Disulfide bondi466 ↔ 471PROSITE-ProRule annotationBy similarity
Disulfide bondi476 ↔ 496PROSITE-ProRule annotationBy similarity
Disulfide bondi512 ↔ 532PROSITE-ProRule annotationBy similarity
Disulfide bondi535 ↔ 555PROSITE-ProRule annotationBy similarity
Disulfide bondi571 ↔ 591PROSITE-ProRule annotationBy similarity
Disulfide bondi594 ↔ 614PROSITE-ProRule annotationBy similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi601N-linked (GlcNAc...) asparagineCurated1
Disulfide bondi632 ↔ 652PROSITE-ProRule annotationBy similarity
Glycosylationi637N-linked (GlcNAc...) asparagineCurated1
Disulfide bondi672 ↔ 692PROSITE-ProRule annotationBy similarity
Disulfide bondi708 ↔ 929PROSITE-ProRule annotationBy similarity
Glycosylationi930N-linked (GlcNAc...) asparagineCurated1

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8JGW0

PRoteomics IDEntifications database

More...
PRIDEi
Q8JGW0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed both maternally and zygotically. Present at the gastrulation and post-segmentation stages.1 Publication

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homotrimer; disulfide-linked.

By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
7955.ENSDARP00000093348

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8JGW0

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini23 – 198Laminin G-likeAdd BLAST176
Domaini312 – 349EGF-like 1; calcium-bindingPROSITE-ProRule annotationAdd BLAST38
Domaini365 – 408EGF-like 2; calcium-bindingPROSITE-ProRule annotationAdd BLAST44
Domaini409 – 451EGF-like 3PROSITE-ProRule annotationAdd BLAST43
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati452 – 484TSP type-3 1Add BLAST33
Repeati485 – 520TSP type-3 2Add BLAST36
Repeati521 – 543TSP type-3 3Add BLAST23
Repeati544 – 579TSP type-3 4Add BLAST36
Repeati580 – 602TSP type-3 5Add BLAST23
Repeati603 – 640TSP type-3 6Add BLAST38
Repeati641 – 680TSP type-3 7Add BLAST40
Repeati681 – 716TSP type-3 8Add BLAST36
Domaini720 – 934TSP C-terminalPROSITE-ProRule annotationAdd BLAST215

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the thrombospondin family.Curated

Keywords - Domaini

EGF-like domain, Repeat, Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QRK8, Eukaryota

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8JGW0

KEGG Orthology (KO)

More...
KOi
K04659

Database of Orthologous Groups

More...
OrthoDBi
120983at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8JGW0

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
4.10.1080.10, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR013320, ConA-like_dom_sf
IPR001881, EGF-like_Ca-bd_dom
IPR000742, EGF-like_dom
IPR018097, EGF_Ca-bd_CS
IPR001791, Laminin_G
IPR024665, Thbs/COMP_coiled-coil
IPR003367, Thrombospondin_3-like_rpt
IPR017897, Thrombospondin_3_rpt
IPR008859, Thrombospondin_C
IPR028974, TSP_type-3_rpt

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF11598, COMP, 1 hit
PF07645, EGF_CA, 2 hits
PF02412, TSP_3, 6 hits
PF05735, TSP_C, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00181, EGF, 4 hits
SM00179, EGF_CA, 2 hits
SM00210, TSPN, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF103647, SSF103647, 3 hits
SSF49899, SSF49899, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01186, EGF_2, 1 hit
PS50026, EGF_3, 3 hits
PS01187, EGF_CA, 2 hits
PS51234, TSP3, 8 hits
PS51236, TSP_CTER, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q8JGW0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAGTMHLLTA VSLILMLSSA NAESTVYNLL TSPDCLPDLL HGGLAEQGVT
60 70 80 90 100
ELYILTTFRI QPGTGNTIFS LYNPRDNSKY FEFSVFGKAN KAILRYLRRD
110 120 130 140 150
GRMSAVTFNK LNLADGEKHR LLFHLKGLEV GHPGGFPHSQ GALPVPGVEL
160 170 180 190 200
HLDCRLVETL RDLPAVFNGL NNHQAVELKT MQGKAQEGLE ELKLAYGDSV
210 220 230 240 250
ENVASLQDCH TQSDSVQALG LNTKQLTTQM LELTKVINEL KDVLIQQVKE
260 270 280 290 300
TSFLRNTISE CQACGLSGAE VVKPKCAPGV CFRDDMCIET AEGVECGPCP
310 320 330 340 350
DGYTGDGYSC DDVDECQFNP CFPGVRCVNM APGFRCEACP LGFTGKPLEG
360 370 380 390 400
VGVAYAQTHK QVCDDIDECK GPDNGGCTAN SICVNSVGSY QCGRCKTGFT
410 420 430 440 450
GDQIRGCKPE KSCGNRLQNP CDPNAQCTEE RDGTITCQCG IGWAGNGYLC
460 470 480 490 500
GKDTDIDGYP DERLRCRDPT CRKDNCVTVP NSGQEDADGD GKGDACDPDA
510 520 530 540 550
DGDGILNEQD NCWLTPNINQ QNSDKDSHGD ACDNCVRVDN PDQRDTDSDG
560 570 580 590 600
LGDACDDDMD GDGLKNFLDN CQRVKNRDQL DRDGDGVGDA CDSCPDIPNP
610 620 630 640 650
NQSDIDNDLV GDSCDTNQDS DGDGHQDSKD NCPMVINSSQ LDTDKDGIGD
660 670 680 690 700
ECDDDDDNDG IPDSLPPGPD NCRLVPNPEQ IDDNNDGVGD ICESDFDQDK
710 720 730 740 750
VIDRIDNCPE NAEITLTDFR AYQTVVLDPE GDAQIDPNWV VLNQGMEIVQ
760 770 780 790 800
TMNSDPGLAV GYTAFSGVDF EGTFHVNTVT DDDYAGFIFG YQDSSSFYVV
810 820 830 840 850
MWKQTEQTYW QATPFRAVAE PGIQLKAVKS KTGPGEHLRN SLWHTGDTND
860 870 880 890 900
QVRLLWKDPR NVGWKDKVSY RWYLQHRPQV GYIRVRFYEG TELVADSGVT
910 920 930 940
IDTTMRGGRL GVFCFSQENI IWSNLKYRCN DTIPEDFQEF STQHGMDPL
Length:949
Mass (Da):103,991
Last modified:October 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBBC9203814CA99CB
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F1R1P9F1R1P9_DANRE
Thrombospondin-4-B
thbs4b
949Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY081009 mRNA Translation: AAL82733.1

NCBI Reference Sequences

More...
RefSeqi
NP_775333.1, NM_173226.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
252850

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dre:252850

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY081009 mRNA Translation: AAL82733.1
RefSeqiNP_775333.1, NM_173226.1

3D structure databases

SMRiQ8JGW0
ModBaseiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000093348

Proteomic databases

PaxDbiQ8JGW0
PRIDEiQ8JGW0

Genome annotation databases

GeneIDi252850
KEGGidre:252850

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
252850
ZFINiZDB-GENE-020708-4, thbs4b

Phylogenomic databases

eggNOGiENOG502QRK8, Eukaryota
InParanoidiQ8JGW0
KOiK04659
OrthoDBi120983at2759
PhylomeDBiQ8JGW0

Enzyme and pathway databases

ReactomeiR-DRE-186797, Signaling by PDGF
R-DRE-216083, Integrin cell surface interactions
R-DRE-3000178, ECM proteoglycans

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q8JGW0

Family and domain databases

Gene3Di4.10.1080.10, 3 hits
InterProiView protein in InterPro
IPR013320, ConA-like_dom_sf
IPR001881, EGF-like_Ca-bd_dom
IPR000742, EGF-like_dom
IPR018097, EGF_Ca-bd_CS
IPR001791, Laminin_G
IPR024665, Thbs/COMP_coiled-coil
IPR003367, Thrombospondin_3-like_rpt
IPR017897, Thrombospondin_3_rpt
IPR008859, Thrombospondin_C
IPR028974, TSP_type-3_rpt
PfamiView protein in Pfam
PF11598, COMP, 1 hit
PF07645, EGF_CA, 2 hits
PF02412, TSP_3, 6 hits
PF05735, TSP_C, 1 hit
SMARTiView protein in SMART
SM00181, EGF, 4 hits
SM00179, EGF_CA, 2 hits
SM00210, TSPN, 1 hit
SUPFAMiSSF103647, SSF103647, 3 hits
SSF49899, SSF49899, 2 hits
PROSITEiView protein in PROSITE
PS01186, EGF_2, 1 hit
PS50026, EGF_3, 3 hits
PS01187, EGF_CA, 2 hits
PS51234, TSP3, 8 hits
PS51236, TSP_CTER, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTSP4B_DANRE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8JGW0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: October 1, 2002
Last modified: October 7, 2020
This is version 118 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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