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Protein

Putative protein FAM10A4

Gene

ST13P4

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Protein uncertaini

Functioni

Caution

Could be the product of a pseudogene.Curated

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Recommended name:
Putative protein FAM10A4
Alternative name(s):
Suppression of tumorigenicity 13 pseudogene 4
Gene namesi
Name:ST13P4
Synonyms:FAM10A4
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

HGNCiHGNC:18487 ST13P4
neXtProtiNX_Q8IZP2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

Pathology & Biotechi

Polymorphism and mutation databases

DMDMi74762505

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001908161 – 240Putative protein FAM10A4Add BLAST240

Proteomic databases

EPDiQ8IZP2
MaxQBiQ8IZP2
PeptideAtlasiQ8IZP2
PRIDEiQ8IZP2
ProteomicsDBi71392

PTM databases

iPTMnetiQ8IZP2
SwissPalmiQ8IZP2

Expressioni

Tissue specificityi

Highly expressed in bone marrow and weakly in placenta, pancreas, heart and HeLa cell line.1 Publication

Organism-specific databases

HPAiHPA047114
HPA047116

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

IntActiQ8IZP2, 4 interactors

Structurei

3D structure databases

ProteinModelPortaliQ8IZP2
SMRiQ8IZP2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati110 – 143TPR 1Add BLAST34
Repeati145 – 177TPR 2Add BLAST33
Repeati179 – 211TPR 3Add BLAST33

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi49 – 105Glu-richAdd BLAST57

Sequence similaritiesi

Belongs to the FAM10 family.Curated

Keywords - Domaini

Repeat, TPR repeat

Phylogenomic databases

eggNOGiKOG1308 Eukaryota
ENOG410XR19 LUCA
HOVERGENiHBG002482
InParanoidiQ8IZP2

Family and domain databases

CDDicd14438 Hip_N, 1 hit
Gene3Di1.25.40.10, 1 hit
InterProiView protein in InterPro
IPR034649 Hip_N
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat
SMARTiView protein in SMART
SM00028 TPR, 3 hits
SUPFAMiSSF48452 SSF48452, 1 hit
PROSITEiView protein in PROSITE
PS50005 TPR, 3 hits
PS50293 TPR_REGION, 1 hit

Sequencei

Sequence statusi: Complete.

Q8IZP2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDPRKVNELR AFVKMCKKDP SILHTQEMRF LREWVESMGG TATQKAKSEE
60 70 80 90 100
NTKEEKPDSK VEEDLKADEP SSEESDLEID KEGVIEPDTD APQEMGDENA
110 120 130 140 150
EITEEVMDQA NDKKVAAIEA LNDGELQKAI DLFTDAIKLN PRLAILYAKR
160 170 180 190 200
ASVFVKLQKP NAAIRDCDRA IEINPDSAQP YKRRGKAHRL LGHWEEAAHD
210 220 230 240
LALACKFDYD EDASAMLKEV QPRAQKIAEH QRKYERKREE
Length:240
Mass (Da):27,407
Last modified:March 1, 2003 - v1
Checksum:i6D2A849E530944E3
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_02364471S → L1 Publication1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF539468 mRNA Translation: AAN16377.1
AL157367 Genomic DNA No translation available.
UniGeneiHs.511834

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiST134_HUMAN
AccessioniPrimary (citable) accession number: Q8IZP2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: March 1, 2003
Last modified: September 12, 2018
This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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