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Entry version 148 (02 Jun 2021)
Sequence version 3 (18 May 2010)
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Protein

Zinc finger protein 654

Gene

ZNF654

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri25 – 47C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri199 – 224C2H2-type 2PROSITE-ProRule annotationAdd BLAST26
Zinc fingeri240 – 262C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri268 – 292C2H2-type 4PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri297 – 321C2H2-type 5PROSITE-ProRule annotationAdd BLAST25

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q8IZM8

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 654
Alternative name(s):
Melanoma-associated antigen
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF654
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:25612, ZNF654

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8IZM8

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000175105.5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134923001

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q8IZM8, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF654

Domain mapping of disease mutations (DMDM)

More...
DMDMi
296453064

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003119461 – 581Zinc finger protein 654Add BLAST581

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei576PhosphoserineBy similarity1
Modified residuei580PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8IZM8

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8IZM8

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q8IZM8

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8IZM8

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8IZM8

PeptideAtlas

More...
PeptideAtlasi
Q8IZM8

PRoteomics IDEntifications database

More...
PRIDEi
Q8IZM8

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
71374

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8IZM8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8IZM8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000175105, Expressed in secondary oocyte and 212 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8IZM8, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8IZM8, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000175105, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
120567, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000312141

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8IZM8, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8IZM8

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni344 – 404DisorderedSequence analysisAdd BLAST61

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi344 – 370Polar residuesSequence analysisAdd BLAST27
Compositional biasi371 – 385Basic and acidic residuesSequence analysisAdd BLAST15
Compositional biasi386 – 404Polar residuesSequence analysisAdd BLAST19

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri25 – 47C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri199 – 224C2H2-type 2PROSITE-ProRule annotationAdd BLAST26
Zinc fingeri240 – 262C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri268 – 292C2H2-type 4PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri297 – 321C2H2-type 5PROSITE-ProRule annotationAdd BLAST25

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_026570_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8IZM8

Identification of Orthologs from Complete Genome Data

More...
OMAi
RHRCVIC

Database of Orthologous Groups

More...
OrthoDBi
355592at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8IZM8

TreeFam database of animal gene trees

More...
TreeFami
TF326007

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00096, zf-C2H2, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00355, ZnF_C2H2, 6 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 5 hits
PS50157, ZINC_FINGER_C2H2_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q8IZM8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLCNKEFLGG HIVRHAQAHQ KKGSFACVIC GRKFRNRGLM QKHLKNHVKK
60 70 80 90 100
IQRQQIAAAQ QDDQEVTALE EINCSSSSIS FENGNSDSKD LEVETLTASS
110 120 130 140 150
EGNKEVIPEH VAEFIEIPIS VPEDVIENVI ENGSPNNSLN NVFKPLTECG
160 170 180 190 200
DDYEEEEDEE GDYEEDDYDL NQETSVIHKI NGTVCHPKDI YATDQEGNFK
210 220 230 240 250
CPALGCVRIF KRIGFLNKHA MTVHPTDLNV RQTVMKWSKG KCKFCQRQFE
260 270 280 290 300
DSQHFIDHLN RHSYPNVYFC LHFNCNESFK LPFQLAQHTK SHRIFQAQCS
310 320 330 340 350
FPECHELFED LPLLYEHEAQ HYLSKTPESS AQPSETILWD VQTDSNPNQE
360 370 380 390 400
KDSSSNEKQT ISLPVSTSKS RKESTEPKTC IESMEKKTDS LVQNGNERSD
410 420 430 440 450
DTVSNISLID QKMPDIEPNS ENNCSSSDIV NGHSEIEQTP LVSSDPALKI
460 470 480 490 500
DTNRIRTENG SILPSVVPQE HNTLPVSQAP SKPNLTSEHT SYGLILTKPY
510 520 530 540 550
VRPLPPSYLD ERYLSMPKRR KFLTDRVDAC SDQDNVYKKS VKRLRCGKCL
560 570 580
TTYCNAEALE AHLAQKKCQT LFGFDSDDES A
Length:581
Mass (Da):65,854
Last modified:May 18, 2010 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8B1FE6C4B1A72A12
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1B0GWA0A0A1B0GWA0_HUMAN
Zinc finger protein 654
ZNF654
1,128Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAN40504 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
The sequence BAA91946 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated
The sequence BAB15007 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti258H → Q in BAA91946 (PubMed:14702039).Curated1
Sequence conflicti294I → T in AAN40504 (Ref. 1) Curated1
Sequence conflicti294I → T in BAA91946 (PubMed:14702039).Curated1
Sequence conflicti548K → E in BAB15007 (PubMed:14702039).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF543494 mRNA Translation: AAN40504.1 Different initiation.
AK001859 mRNA Translation: BAA91946.1 Different initiation.
AK024795 mRNA Translation: BAB15007.1 Different initiation.
AC119733 Genomic DNA No translation available.
AC128650 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
NP_060763.2, NM_018293.2

Genome annotation databases

UCSC genome browser

More...
UCSCi
uc003dqv.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF543494 mRNA Translation: AAN40504.1 Different initiation.
AK001859 mRNA Translation: BAA91946.1 Different initiation.
AK024795 mRNA Translation: BAB15007.1 Different initiation.
AC119733 Genomic DNA No translation available.
AC128650 Genomic DNA No translation available.
RefSeqiNP_060763.2, NM_018293.2

3D structure databases

SMRiQ8IZM8
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi120567, 1 interactor
STRINGi9606.ENSP00000312141

PTM databases

iPTMnetiQ8IZM8
PhosphoSitePlusiQ8IZM8

Genetic variation databases

BioMutaiZNF654
DMDMi296453064

Proteomic databases

EPDiQ8IZM8
jPOSTiQ8IZM8
MassIVEiQ8IZM8
MaxQBiQ8IZM8
PaxDbiQ8IZM8
PeptideAtlasiQ8IZM8
PRIDEiQ8IZM8
ProteomicsDBi71374

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
32053, 125 antibodies

The DNASU plasmid repository

More...
DNASUi
55279

Genome annotation databases

UCSCiuc003dqv.4, human

Organism-specific databases

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZNF654
HGNCiHGNC:25612, ZNF654
HPAiENSG00000175105, Low tissue specificity
neXtProtiNX_Q8IZM8
PharmGKBiPA134923001
VEuPathDBiHostDB:ENSG00000175105.5

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1721, Eukaryota
HOGENOMiCLU_026570_1_0_1
InParanoidiQ8IZM8
OMAiRHRCVIC
OrthoDBi355592at2759
PhylomeDBiQ8IZM8
TreeFamiTF326007

Enzyme and pathway databases

PathwayCommonsiQ8IZM8

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
55279, 6 hits in 996 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
55279
PharosiQ8IZM8, Tbio

Protein Ontology

More...
PROi
PR:Q8IZM8
RNActiQ8IZM8, protein

Gene expression databases

BgeeiENSG00000175105, Expressed in secondary oocyte and 212 other tissues
ExpressionAtlasiQ8IZM8, baseline and differential
GenevisibleiQ8IZM8, HS

Family and domain databases

InterProiView protein in InterPro
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF00096, zf-C2H2, 1 hit
SMARTiView protein in SMART
SM00355, ZnF_C2H2, 6 hits
PROSITEiView protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 5 hits
PS50157, ZINC_FINGER_C2H2_2, 2 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN654_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8IZM8
Secondary accession number(s): Q9H791, Q9NV14
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 4, 2007
Last sequence update: May 18, 2010
Last modified: June 2, 2021
This is version 148 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
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