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Entry version 139 (13 Feb 2019)
Sequence version 3 (11 Jan 2011)
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Protein

Zinc finger protein 34

Gene

ZNF34

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri195 – 217C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri251 – 273C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri279 – 301C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri307 – 329C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri335 – 357C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri363 – 385C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri391 – 413C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri419 – 441C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri447 – 469C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri475 – 497C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri503 – 525C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri531 – 553C2H2-type 12PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-212436 Generic Transcription Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 34
Alternative name(s):
Zinc finger protein KOX32
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF34
Synonyms:KOX32
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000196378.11

Human Gene Nomenclature Database

More...
HGNCi
HGNC:13098 ZNF34

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
194526 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8IZ26

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
80778

Open Targets

More...
OpenTargetsi
ENSG00000196378

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA37673

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF34

Domain mapping of disease mutations (DMDM)

More...
DMDMi
317373492

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000473651 – 560Zinc finger protein 34Add BLAST560

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei113PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
Q8IZ26

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8IZ26

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8IZ26

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8IZ26

PeptideAtlas

More...
PeptideAtlasi
Q8IZ26

PRoteomics IDEntifications database

More...
PRIDEi
Q8IZ26

ProteomicsDB human proteome resource

More...
ProteomicsDBi
71275

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8IZ26

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8IZ26

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000196378 Expressed in 151 organ(s), highest expression level in cerebellar hemisphere

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
Q8IZ26 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8IZ26 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA053925
HPA060755
HPA066805

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
123310, 7 interactors

Protein interaction database and analysis system

More...
IntActi
Q8IZ26, 3 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000341528

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q8IZ26

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8IZ26

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini35 – 108KRABPROSITE-ProRule annotationAdd BLAST74

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri195 – 217C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri251 – 273C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri279 – 301C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri307 – 329C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri335 – 357C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri363 – 385C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri391 – 413C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri419 – 441C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri447 – 469C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri475 – 497C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri503 – 525C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri531 – 553C2H2-type 12PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721 Eukaryota
COG5048 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154712

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000234617

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG018163

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8IZ26

KEGG Orthology (KO)

More...
KOi
K09228

Identification of Orthologs from Complete Genome Data

More...
OMAi
NQRPNLM

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8IZ26

TreeFam database of animal gene trees

More...
TreeFami
TF337055

Family and domain databases

Conserved Domains Database

More...
CDDi
cd07765 KRAB_A-box, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR030753 ZNF34
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

The PANTHER Classification System

More...
PANTHERi
PTHR24377:SF717 PTHR24377:SF717, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 12 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 12 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 7 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 12 hits
PS50157 ZINC_FINGER_C2H2_2, 12 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q8IZ26-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLLLLSDQLL LTALRKPNPQ AMAALFLSAP PQAEVTFEDV AVYLSREEWG
60 70 80 90 100
RLGPAQRGLY RDVMLETYGN LVSLGVGPAG PKPGVISQLE RGDEPWVLDV
110 120 130 140 150
QGTSGKEHLR VNSPALGTRT EYKELTSQET FGEEDPQGSE PVEACDHISK
160 170 180 190 200
SEGSLEKLVE QRGPRAVTLT NGESSRESGG NLRLLSRPVP DQRPHKCDIC
210 220 230 240 250
EQSFEQRSYL NNHKRVHRSK KTNTVRNSGE IFSANLVVKE DQKIPTGKKL
260 270 280 290 300
HYCSYCGKTF RYSANLVKHQ RLHTEEKPYK CDECGKAFSQ SCEFINHRRM
310 320 330 340 350
HSGEIPYRCD ECGKTFTRRP NLMKHQRIHT GEKPYKCGEC GKHFSAYSSL
360 370 380 390 400
IYHQRIHTGE KPYKCNDCGK AFSDGSILIR HRRTHTGEKP FECKECGKGF
410 420 430 440 450
TQSSNLIQHQ RIHTGEKPYK CNECEKAFIQ KTKLVEHQRS HTGEKPYECN
460 470 480 490 500
DCGKVFSQST HLIQHQRIHT GEKPYKCSEC GKAFHNSSRL IHHQRLHHGE
510 520 530 540 550
KPYRCSDCKK AFSQSTYLIQ HRRIHTGEKP YKCSECGKAF RHSSNMCQHQ
560
RIHLREDFSM
Length:560
Mass (Da):64,038
Last modified:January 11, 2011 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB66056E75C42C324
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0C4DG42A0A0C4DG42_HUMAN
Zinc finger protein 34
ZNF34
539Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PSD0E9PSD0_HUMAN
Zinc finger protein 34
ZNF34
264Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PNZ6E9PNZ6_HUMAN
Zinc finger protein 34
ZNF34
158Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH04480 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence AAH28136 differs from that shown. Codon in position 67 corresponds to a stop codon in genome.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL833814 mRNA Translation: CAD38677.1
CH471162 Genomic DNA Translation: EAW82055.1
CH471162 Genomic DNA Translation: EAW82056.1
BC004480 mRNA Translation: AAH04480.1 Different initiation.
BC028136 mRNA Translation: AAH28136.1 Sequence problems.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS47945.1

NCBI Reference Sequences

More...
RefSeqi
NP_001273698.1, NM_001286769.1
NP_085057.3, NM_030580.4
XP_011515616.1, XM_011517314.2
XP_011515617.1, XM_011517315.2
XP_011515618.1, XM_011517316.2
XP_011515620.1, XM_011517318.2
XP_016869361.1, XM_017013872.1
XP_016869362.1, XM_017013873.1
XP_016869363.1, XM_017013874.1
XP_016869364.1, XM_017013875.1

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.631854

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000343459; ENSP00000341528; ENSG00000196378

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
80778

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:80778

UCSC genome browser

More...
UCSCi
uc003zdx.6 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL833814 mRNA Translation: CAD38677.1
CH471162 Genomic DNA Translation: EAW82055.1
CH471162 Genomic DNA Translation: EAW82056.1
BC004480 mRNA Translation: AAH04480.1 Different initiation.
BC028136 mRNA Translation: AAH28136.1 Sequence problems.
CCDSiCCDS47945.1
RefSeqiNP_001273698.1, NM_001286769.1
NP_085057.3, NM_030580.4
XP_011515616.1, XM_011517314.2
XP_011515617.1, XM_011517315.2
XP_011515618.1, XM_011517316.2
XP_011515620.1, XM_011517318.2
XP_016869361.1, XM_017013872.1
XP_016869362.1, XM_017013873.1
XP_016869363.1, XM_017013874.1
XP_016869364.1, XM_017013875.1
UniGeneiHs.631854

3D structure databases

ProteinModelPortaliQ8IZ26
SMRiQ8IZ26
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi123310, 7 interactors
IntActiQ8IZ26, 3 interactors
STRINGi9606.ENSP00000341528

PTM databases

iPTMnetiQ8IZ26
PhosphoSitePlusiQ8IZ26

Polymorphism and mutation databases

BioMutaiZNF34
DMDMi317373492

Proteomic databases

EPDiQ8IZ26
jPOSTiQ8IZ26
MaxQBiQ8IZ26
PaxDbiQ8IZ26
PeptideAtlasiQ8IZ26
PRIDEiQ8IZ26
ProteomicsDBi71275

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
80778
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000343459; ENSP00000341528; ENSG00000196378
GeneIDi80778
KEGGihsa:80778
UCSCiuc003zdx.6 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
80778
DisGeNETi80778
EuPathDBiHostDB:ENSG00000196378.11

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZNF34
HGNCiHGNC:13098 ZNF34
HPAiHPA053925
HPA060755
HPA066805
MIMi194526 gene
neXtProtiNX_Q8IZ26
OpenTargetsiENSG00000196378
PharmGKBiPA37673

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00940000154712
HOGENOMiHOG000234617
HOVERGENiHBG018163
InParanoidiQ8IZ26
KOiK09228
OMAiNQRPNLM
OrthoDBi1318335at2759
PhylomeDBiQ8IZ26
TreeFamiTF337055

Enzyme and pathway databases

ReactomeiR-HSA-212436 Generic Transcription Pathway

Miscellaneous databases

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
ZNF34

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
80778

Protein Ontology

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PROi
PR:Q8IZ26

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000196378 Expressed in 151 organ(s), highest expression level in cerebellar hemisphere
ExpressionAtlasiQ8IZ26 baseline and differential
GenevisibleiQ8IZ26 HS

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR030753 ZNF34
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PANTHERiPTHR24377:SF717 PTHR24377:SF717, 1 hit
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 12 hits
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 12 hits
SUPFAMiSSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 7 hits
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 12 hits
PS50157 ZINC_FINGER_C2H2_2, 12 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZNF34_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8IZ26
Secondary accession number(s): D3DWN1, Q9BSZ0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 23, 2004
Last sequence update: January 11, 2011
Last modified: February 13, 2019
This is version 139 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 8
    Human chromosome 8: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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