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UniProtKB - Q8IYR0 (CF206_HUMAN)

Entry version 131 (07 Apr 2021)
Sequence version 2 (29 Aug 2003)
Previous versions | rss
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Protein

Cilia- and flagella-associated protein 206

Gene

CFAP206

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Essential for sperm motility and is involved in the regulation of the beating frequency of motile cilia on the epithelial cells of the respiratory tract (By similarity). Required for the establishment of radial spokes in sperm flagella (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCilium biogenesis/degradation

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q8IYR0

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cilia- and flagella-associated protein 206Curated
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CFAP206Imported
Synonyms:C6orf165Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:21405, CFAP206

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q8IYR0

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000213204.8
HostDB:ENSG00000272514.5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cell projection, Cilium, Cytoplasm, Cytoskeleton

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000213204
ENSG00000272514

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134983540

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q8IYR0, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		CFAP206

Domain mapping of disease mutations (DMDM)

More...DMDMi		34395551

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000895531 – 622Cilia- and flagella-associated protein 206Add BLAST622

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q8IYR0

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q8IYR0

PeptideAtlas

More...PeptideAtlasi		Q8IYR0

PRoteomics IDEntifications database

More...PRIDEi		Q8IYR0

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		71214

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q8IYR0

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q8IYR0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000213204, Expressed in testis and 112 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q8IYR0, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q8IYR0, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000272514, Group enriched (fallopian tube, testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Q8IYR0
With#Exp.IntAct
ADAMTSL4 - isoform 3 [Q6UY14-3]6EBI-749051,EBI-10173507
ANKRD55 [Q3KP44]3EBI-749051,EBI-14493093
APIP [Q96GX9]3EBI-749051,EBI-359248
ATPAF2 [Q8N5M1]3EBI-749051,EBI-1166928
BANP [Q8N9N5]3EBI-749051,EBI-744695
BANP - isoform 2 [Q8N9N5-2]3EBI-749051,EBI-11524452
BLZF1 [Q9H2G9]3EBI-749051,EBI-2548012
C1orf94 [Q6P1W5]4EBI-749051,EBI-946029
C9orf153 - isoform 2 [Q5TBE3-2]3EBI-749051,EBI-12159293
CDX2 [Q99626]3EBI-749051,EBI-10899513
CEP57L1 - isoform 2 [Q8IYX8-2]3EBI-749051,EBI-10181988
CFP [P27918]3EBI-749051,EBI-9038570
CPSF7 - isoform 3 [Q8N684-3]3EBI-749051,EBI-11523759
CRX [O43186]3EBI-749051,EBI-748171
CYSRT1 [A8MQ03]3EBI-749051,EBI-3867333
DISC1 - isoform 2 [Q9NRI5-2]3EBI-749051,EBI-11988027
EIF4ENIF1 [Q9NRA8]3EBI-749051,EBI-301024
GFAP [P14136]3EBI-749051,EBI-744302
GLYR1 [Q49A26]3EBI-749051,EBI-2804292
GPRASP2 [Q96D09]6EBI-749051,EBI-473189
GSE1 [Q14687]3EBI-749051,EBI-372619
IHO1 [Q8IYA8]3EBI-749051,EBI-8638439
IKZF3 [Q9UKT9]3EBI-749051,EBI-747204
KIAA1328 [Q86T90]3EBI-749051,EBI-3437878
KLHL3 [Q8N4I8]3EBI-749051,EBI-10230467
KRT31 [Q15323]3EBI-749051,EBI-948001
KRT34 [O76011]3EBI-749051,EBI-1047093
KRT40 [Q6A162]6EBI-749051,EBI-10171697
KRT75 [O95678]3EBI-749051,EBI-2949715
KRT76 [Q01546]3EBI-749051,EBI-2952745
KRTAP26-1 [Q6PEX3]3EBI-749051,EBI-3957672
LZTS2 [Q9BRK4]3EBI-749051,EBI-741037
MAGED1 [Q9Y5V3]3EBI-749051,EBI-716006
MEOX2 [Q6FHY5]3EBI-749051,EBI-16439278
MIF4GD - isoform 2 [A9UHW6-2]3EBI-749051,EBI-9118295
NME4 [O00746]3EBI-749051,EBI-744871
PIH1D2 [Q8WWB5]3EBI-749051,EBI-10232538
PSMA1 [P25786]3EBI-749051,EBI-359352
PSMC5 [P62195]3EBI-749051,EBI-357745
REL - isoform 2 [Q04864-2]3EBI-749051,EBI-10829018
ROCK1 [Q13464]3EBI-749051,EBI-876651
SAMD3 [Q8N6K7]3EBI-749051,EBI-748741
SAXO1 [Q8IYX7]3EBI-749051,EBI-3957636
SORBS3 [O60504]3EBI-749051,EBI-741237
SOX30 [O94993]4EBI-749051,EBI-742973
TADA2B - isoform 3 [Q86TJ2-3]3EBI-749051,EBI-18173581
TASOR2 [Q5VWN6]3EBI-749051,EBI-745958
TCF12 [Q99081]3EBI-749051,EBI-722877
TEKT1 [Q969V4]3EBI-749051,EBI-10180409
TFIP11 [Q9UBB9]4EBI-749051,EBI-1105213
TLE5 [Q08117]3EBI-749051,EBI-717810
TRIM27 [P14373]3EBI-749051,EBI-719493
TRIM54 [Q9BYV2]3EBI-749051,EBI-2130429
UBXN11 [Q5T124]4EBI-749051,EBI-746004
UBXN11 - isoform 6 [Q5T124-6]3EBI-749051,EBI-11524408
USHBP1 [Q8N6Y0]3EBI-749051,EBI-739895
VPS52 [Q8N1B4]3EBI-749051,EBI-2799833
ZNF511 [Q8NB15]3EBI-749051,EBI-10269136

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		127543, 66 interactors

Protein interaction database and analysis system

More...IntActi		Q8IYR0, 59 interactors

Molecular INTeraction database

More...MINTi		Q8IYR0

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000358575

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q8IYR0, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CFAP206 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502QTGJ, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000016036

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_030061_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q8IYR0

Identification of Orthologs from Complete Genome Data

More...OMAi		NQEWLFP

Database of Orthologous Groups

More...OrthoDBi		357137at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q8IYR0

TreeFam database of animal gene trees

More...TreeFami		TF323439

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR021897, FAP206

The PANTHER Classification System

More...PANTHERi		PTHR21442, PTHR21442, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF12018, FAP206, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q8IYR0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPPTQAESVI RSIIREIGQE CAAHGEIVSE TLIAFMVKAV VLDPSNGFNM 
        60         70         80         90        100
DRTLMKSDVQ NLVKLCMTRL LDTKNPSLDT IKMQVYFDMN YTNRVEFLEE 
       110        120        130        140        150
HHRVLESRLG SVTREITDNR ACAKEELESL YRKIISYVLL RSGLGSPTDI 
       160        170        180        190        200
KTVREVTAAL QSVFPQAELG TFLTLSKKDK ERQLKELTMI VTGIRLFNRD 
       210        220        230        240        250
CGKGGEGIDD LPAVLHVAIP ATMQHIDYQL ETARSQVYRY TAILEKAAND 
       260        270        280        290        300
PLMRAELQPY MLKEALYNIR QYEVFLQIIL SDIITGAQEV EMMTKQLGAH 
       310        320        330        340        350
LEQLKMTIKS KIAVPTSQVF PIFIALSTLW TSLQDETIVV GVLSNLFTHI 
       360        370        380        390        400
QPFLGAHELY FPERVMQCHL NGATVKTDVC RMKEHMEDRV NVADFRKLEW 
       410        420        430        440        450
LFPETTANFD KLLIQYRGFC AYTFAATDGL LLPGNPAIGI LKYKEKYYTF 
       460        470        480        490        500
NSKDAAYSFA ENPEHYIDIV REKAKKNTEL IQLLELHQQF ETFIPYSQMR 
       510        520        530        540        550
DADKHYIKPI TKCESSTQTN THILPPTIVR SYEWNEWELR RKAIKLANLR 
       560        570        580        590        600
QKVTHSVQTD LSHLRRENCS QVYPPKDTST QSMREDSTGV PRPQIYLAGL 
       610        620 
RGGKSEITDE VKVNLTRDVD ET
Length:622
Mass (Da):71,193
Last modified:August 29, 2003 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEC3818B8596C0B1E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D6RBZ4D6RBZ4_HUMAN
Cilia- and flagella-associated prot...
CFAP206
251Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6R9L9D6R9L9_HUMAN
Cilia- and flagella-associated prot...
CFAP206
95Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC04234 differs from that shown. Intron retention.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti489Q → R in BAF85273 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_033679154R → K. Corresponds to variant dbSNP:rs13219364Ensembl.1
Natural variantiVAR_033680170G → A. Corresponds to variant dbSNP:rs16879281Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK093830 mRNA Translation: BAC04234.1 Sequence problems.
AK292584 mRNA Translation: BAF85273.1
AL049697 Genomic DNA No translation available.
CH471051 Genomic DNA Translation: EAW48594.1
CH471051 Genomic DNA Translation: EAW48596.1
CH471051 Genomic DNA Translation: EAW48598.1
BC035083 mRNA Translation: AAH35083.2

The Consensus CDS (CCDS) project

More...CCDSi		CCDS34498.1

NCBI Reference Sequences

More...RefSeqi		NP_001026913.1, NM_001031743.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000369562; ENSP00000358575; ENSG00000272514

Database of genes from NCBI RefSeq genomes

More...GeneIDi		154313

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:154313

UCSC genome browser

More...UCSCi		uc003plv.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK093830 mRNA Translation: BAC04234.1 Sequence problems.
AK292584 mRNA Translation: BAF85273.1
AL049697 Genomic DNA No translation available.
CH471051 Genomic DNA Translation: EAW48594.1
CH471051 Genomic DNA Translation: EAW48596.1
CH471051 Genomic DNA Translation: EAW48598.1
BC035083 mRNA Translation: AAH35083.2
CCDSiCCDS34498.1
RefSeqiNP_001026913.1, NM_001031743.2

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi127543, 66 interactors
IntActiQ8IYR0, 59 interactors
MINTiQ8IYR0
STRINGi9606.ENSP00000358575

PTM databases

iPTMnetiQ8IYR0
PhosphoSitePlusiQ8IYR0

Genetic variation databases

BioMutaiCFAP206
DMDMi34395551

Proteomic databases

MassIVEiQ8IYR0
PaxDbiQ8IYR0
PeptideAtlasiQ8IYR0
PRIDEiQ8IYR0
ProteomicsDBi71214

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		73997, 43 antibodies

Genome annotation databases

EnsembliENST00000369562; ENSP00000358575; ENSG00000272514
GeneIDi154313
KEGGihsa:154313
UCSCiuc003plv.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		154313

GeneCards: human genes, protein and diseases

More...GeneCardsi		CFAP206
HGNCiHGNC:21405, CFAP206
HPAiENSG00000272514, Group enriched (fallopian tube, testis)
neXtProtiNX_Q8IYR0
OpenTargetsiENSG00000213204
ENSG00000272514
PharmGKBiPA134983540
VEuPathDBiHostDB:ENSG00000213204.8
HostDB:ENSG00000272514.5

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG502QTGJ, Eukaryota
GeneTreeiENSGT00390000016036
HOGENOMiCLU_030061_0_0_1
InParanoidiQ8IYR0
OMAiNQEWLFP
OrthoDBi357137at2759
PhylomeDBiQ8IYR0
TreeFamiTF323439

Enzyme and pathway databases

PathwayCommonsiQ8IYR0

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		154313, 2 hits in 968 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		CFAP206, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		154313
PharosiQ8IYR0, Tdark

Protein Ontology

More...PROi		PR:Q8IYR0
RNActiQ8IYR0, protein

Gene expression databases

BgeeiENSG00000213204, Expressed in testis and 112 other tissues
ExpressionAtlasiQ8IYR0, baseline and differential
GenevisibleiQ8IYR0, HS

Family and domain databases

InterProiView protein in InterPro
IPR021897, FAP206
PANTHERiPTHR21442, PTHR21442, 1 hit
PfamiView protein in Pfam
PF12018, FAP206, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCF206_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8IYR0
Secondary accession number(s): A8K969, E1P507, Q8N9U4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 29, 2003
Last sequence update: August 29, 2003
Last modified: April 7, 2021
This is version 131 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. SIMILARITY comments
    Index of protein domains and families
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