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UniProtKB - Q8IYM2 (SLN12_HUMAN)

Entry version 121 (07 Apr 2021)
Sequence version 2 (03 Apr 2007)
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Protein

Schlafen family member 12

Gene

SLFN12

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q8IYM2

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Schlafen family member 12
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SLFN12
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:25500, SLFN12

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		614955, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q8IYM2

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000172123.12

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		55106

Open Targets

More...OpenTargetsi		ENSG00000172123

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA144596359

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q8IYM2, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		SLFN12

Domain mapping of disease mutations (DMDM)

More...DMDMi		143585256

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002829841 – 578Schlafen family member 12Add BLAST578

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q8IYM2

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q8IYM2

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q8IYM2

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q8IYM2

PeptideAtlas

More...PeptideAtlasi		Q8IYM2

PRoteomics IDEntifications database

More...PRIDEi		Q8IYM2

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		71204

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q8IYM2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q8IYM2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000172123, Expressed in monocyte and 151 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q8IYM2, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q8IYM2, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000172123, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		120416, 6 interactors

Protein interaction database and analysis system

More...IntActi		Q8IYM2, 21 interactors

Molecular INTeraction database

More...MINTi		Q8IYM2

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000378063

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q8IYM2, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q8IYM2

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the Schlafen family. Subgroup II subfamily.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502RU3F, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00410000025651

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_034558_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q8IYM2

Identification of Orthologs from Complete Genome Data

More...OMAi		CMEKKNI

Database of Orthologous Groups

More...OrthoDBi		211385at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q8IYM2

TreeFam database of animal gene trees

More...TreeFami		TF337168

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.30.950.30, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR029684, Schlafen
IPR007421, Schlafen_AlbA_2_dom
IPR038461, Schlafen_AlbA_2_dom_sf

The PANTHER Classification System

More...PANTHERi		PTHR12155, PTHR12155, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF04326, AlbA_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q8IYM2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNISVDLETN YAELVLDVGR VTLGENSRKK MKDCKLRKKQ NESVSRAMCA 
        60         70         80         90        100
LLNSGGGVIK AEIENEDYSY TKDGIGLDLE NSFSNILLFV PEYLDFMQNG 
       110        120        130        140        150
NYFLIFVKSW SLNTSGLRIT TLSSNLYKRD ITSAKVMNAT AALEFLKDMK 
       160        170        180        190        200
KTRGRLYLRP ELLAKRPCVD IQEENNMKAL AGVFFDRTEL DRKEKLTFTE 
       210        220        230        240        250
STHVEIKNFS TEKLLQRIKE ILPQYVSAFA NTDGGYLFIG LNEDKEIIGF 
       260        270        280        290        300
KAEMSDLDDL EREIEKSIRK MPVHHFCMEK KKINYSCKFL GVYDKGSLCG 
       310        320        330        340        350
YVCALRVERF CCAVFAKEPD SWHVKDNRVM QLTRKEWIQF MVEAEPKFSS 
       360        370        380        390        400
SYEEVISQIN TSLPAPHSWP LLEWQRQRHH CPGLSGRITY TPENLCRKLF 
       410        420        430        440        450
LQHEGLKQLI CEEMDSVRKG SLIFSRSWSV DLGLQENHKV LCDALLISQD 
       460        470        480        490        500
SPPVLYTFHM VQDEEFKGYS TQTALTLKQK LAKIGGYTKK VCVMTKIFYL 
       510        520        530        540        550
SPEGMTSCQY DLRSQVIYPE SYYFTRRKYL LKALFKALKR LKSLRDQFSF 
       560        570 
AENLYQIIGI DCFQKNDKKM FKSCRRLT
Length:578
Mass (Da):66,972
Last modified:April 3, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i858DEC808A50E753
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
C9J4K7C9J4K7_HUMAN
Schlafen family member 12
SLFN12
115Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JIA1C9JIA1_HUMAN
Schlafen family member 12
SLFN12
69Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti361T → A in BAA91512 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_03144743S → R1 PublicationCorresponds to variant dbSNP:rs1849733Ensembl.1
Natural variantiVAR_031448168C → R1 PublicationCorresponds to variant dbSNP:rs2586514Ensembl.1
Natural variantiVAR_053877448S → P. Corresponds to variant dbSNP:rs12946189Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK001122 mRNA Translation: BAA91512.1
AK291826 mRNA Translation: BAF84515.1
BC035605 mRNA Translation: AAH35605.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS11295.1

NCBI Reference Sequences

More...RefSeqi		NP_001275938.1, NM_001289009.1
NP_060512.3, NM_018042.4
XP_005258052.1, XM_005257995.4
XP_011523269.1, XM_011524967.2
XP_016880298.1, XM_017024809.1
XP_016880299.1, XM_017024810.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000304905; ENSP00000302077; ENSG00000172123
ENST00000394562; ENSP00000378063; ENSG00000172123
ENST00000452764; ENSP00000394903; ENSG00000172123

Database of genes from NCBI RefSeq genomes

More...GeneIDi		55106

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:55106

UCSC genome browser

More...UCSCi		uc002hji.6, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK001122 mRNA Translation: BAA91512.1
AK291826 mRNA Translation: BAF84515.1
BC035605 mRNA Translation: AAH35605.1
CCDSiCCDS11295.1
RefSeqiNP_001275938.1, NM_001289009.1
NP_060512.3, NM_018042.4
XP_005258052.1, XM_005257995.4
XP_011523269.1, XM_011524967.2
XP_016880298.1, XM_017024809.1
XP_016880299.1, XM_017024810.1

3D structure databases

SMRiQ8IYM2
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi120416, 6 interactors
IntActiQ8IYM2, 21 interactors
MINTiQ8IYM2
STRINGi9606.ENSP00000378063

PTM databases

iPTMnetiQ8IYM2
PhosphoSitePlusiQ8IYM2

Genetic variation databases

BioMutaiSLFN12
DMDMi143585256

Proteomic databases

EPDiQ8IYM2
jPOSTiQ8IYM2
MassIVEiQ8IYM2
PaxDbiQ8IYM2
PeptideAtlasiQ8IYM2
PRIDEiQ8IYM2
ProteomicsDBi71204

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		43970, 120 antibodies

Genome annotation databases

EnsembliENST00000304905; ENSP00000302077; ENSG00000172123
ENST00000394562; ENSP00000378063; ENSG00000172123
ENST00000452764; ENSP00000394903; ENSG00000172123
GeneIDi55106
KEGGihsa:55106
UCSCiuc002hji.6, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		55106
DisGeNETi55106

GeneCards: human genes, protein and diseases

More...GeneCardsi		SLFN12
HGNCiHGNC:25500, SLFN12
HPAiENSG00000172123, Low tissue specificity
MIMi614955, gene
neXtProtiNX_Q8IYM2
OpenTargetsiENSG00000172123
PharmGKBiPA144596359
VEuPathDBiHostDB:ENSG00000172123.12

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG502RU3F, Eukaryota
GeneTreeiENSGT00410000025651
HOGENOMiCLU_034558_0_0_1
InParanoidiQ8IYM2
OMAiCMEKKNI
OrthoDBi211385at2759
PhylomeDBiQ8IYM2
TreeFamiTF337168

Enzyme and pathway databases

PathwayCommonsiQ8IYM2

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		55106, 5 hits in 983 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		SLFN12, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		55106
PharosiQ8IYM2, Tbio

Protein Ontology

More...PROi		PR:Q8IYM2
RNActiQ8IYM2, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000172123, Expressed in monocyte and 151 other tissues
ExpressionAtlasiQ8IYM2, baseline and differential
GenevisibleiQ8IYM2, HS

Family and domain databases

Gene3Di3.30.950.30, 1 hit
InterProiView protein in InterPro
IPR029684, Schlafen
IPR007421, Schlafen_AlbA_2_dom
IPR038461, Schlafen_AlbA_2_dom_sf
PANTHERiPTHR12155, PTHR12155, 1 hit
PfamiView protein in Pfam
PF04326, AlbA_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSLN12_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8IYM2
Secondary accession number(s): A8K711, Q9NP47
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 3, 2007
Last sequence update: April 3, 2007
Last modified: April 7, 2021
This is version 121 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
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