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Entry version 130 (31 Jul 2019)
Sequence version 2 (20 Mar 2007)
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Protein

EF-hand calcium-binding domain-containing protein 13

Gene

EFCAB13

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandCalcium

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
EF-hand calcium-binding domain-containing protein 13
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:EFCAB13
Synonyms:C17orf57
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:26864 EFCAB13

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8IY85

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
124989

Open Targets

More...
OpenTargetsi
ENSG00000178852

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142672240

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
EFCAB13

Domain mapping of disease mutations (DMDM)

More...
DMDMi
134034056

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002811101 – 973EF-hand calcium-binding domain-containing protein 13Add BLAST973

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8IY85

PeptideAtlas

More...
PeptideAtlasi
Q8IY85

PRoteomics IDEntifications database

More...
PRIDEi
Q8IY85

ProteomicsDB human proteome resource

More...
ProteomicsDBi
32238
71125 [Q8IY85-1]
71126 [Q8IY85-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8IY85

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8IY85

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000178852 Expressed in 106 organ(s), highest expression level in left coronary artery

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8IY85 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8IY85 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
CAB002501
HPA021633
HPA023249
HPA026561

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000332111

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8IY85

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini488 – 523EF-hand 1Add BLAST36
Domaini524 – 559EF-hand 2Add BLAST36
Domaini633 – 668EF-hand 3Add BLAST36
Domaini756 – 791EF-hand 4Add BLAST36
Domaini792 – 827EF-hand 5Add BLAST36
Domaini864 – 899EF-hand 6Add BLAST36

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0027 Eukaryota
COG5126 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000004027

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000111932

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8IY85

Identification of Orthologs from Complete Genome Data

More...
OMAi
ACKIFSK

Database of Orthologous Groups

More...
OrthoDBi
222861at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8IY85

TreeFam database of animal gene trees

More...
TreeFami
TF337478

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011992 EF-hand-dom_pair

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47473 SSF47473, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8IY85-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
METKVHLFCQ AEENIDLLDD GSNSFATDLS SGTINHKKYI KFSKTIEKEI
60 70 80 90 100
SPEIRSLSPE YKKIFETSII FCGEEKSSDF SGEKKVGRKS LQVQQHSKRT
110 120 130 140 150
EIIPPFLKLS KEKVTRKENS LCKLPNQYSV HKTSSPLCTS SAITREKEML
160 170 180 190 200
SNLYMTLYDE VTHGYLHSKE LSALHKACKI FSKIRSGKIY VNDLPVILCI
210 220 230 240 250
LRISISDLEM RQALKTVDID AFQDALKIFC RIKGGRVSTD DVFAVLDSMG
260 270 280 290 300
IPINREILEE VTKHTYIDSN HMVDIGDIIF TLNELQEQYE DVSITEGSPL
310 320 330 340 350
NEITSDRKLS SVAGCYLKYK KKNSLSSKLP EPSISKKLNK KSNQYYSKIM
360 370 380 390 400
ENDDLESKRP KNTWQIRKFL GGVGSSNVGV QEPYSKNGIN FKKHSEKGEI
410 420 430 440 450
HDSKSKPQSL KSSTSLSKSL DKSDISSIPK LQKPAVRKHS SLQKQVSSTE
460 470 480 490 500
KTAISTLENF CEAISKLQEN YIAAEELQSI LPSTGINLLD EEFQKIVTDT
510 520 530 540 550
SRNENGMVEL DDFVNALAKE RSFPECNALP GVIKAIDKIK DKNVDYEDLN
560 570 580 590 600
TCLQNFGIYL SKPEFKKITE LTEAGETKKV NFKEFIDTMM SNTECFSEKL
610 620 630 640 650
VLPDAIETLD DLRKETMSVS DLWNTLSSLN SNLKKDEFLA ALELVTVDEG
660 670 680 690 700
DKVQFEEFAK VVRNMRDAAR LEELQEVVLA ADLLEGDMIA GKNLEDFLRN
710 720 730 740 750
VGIKSPKEEV EKILQSDFVS EDNMVNIKDC MRALRDTQKF SNYIDFRKEA
760 770 780 790 800
SNLKLPKVNE IKEAANILSH VDNGKIGIPD LEHALKCLNV NLTEEDFNEA
810 820 830 840 850
LNCCNVSDNM EVDLKDFLMK MKESPHFQKS KATQILLATT QILQNDLVDV
860 870 880 890 900
SDLKTLLMDK DLHTANAILT VMLRHVPEHE SGKVSIQEFM TKLSDILTIP
910 920 930 940 950
KAAGKFYLIC TYCPDLERQA VVYMLKTIQD SIVKAQVSKK QYNMNIKQHK
960 970
ISLHNFCLNS KANIAKLNPN SKF
Length:973
Mass (Da):110,129
Last modified:March 20, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD46091F56D7DE1A9
GO
Isoform 2 (identifier: Q8IY85-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     173-269: ALHKACKIFS...EVTKHTYIDS → G
     880-880: E → G
     881-973: Missing.

Show »
Length:784
Mass (Da):88,630
Checksum:iB417493C1570516E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H0YBI2H0YBI2_HUMAN
EF-hand calcium-binding domain-cont...
EFCAB13
200Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RI18E5RI18_HUMAN
EF-hand calcium-binding domain-cont...
EFCAB13
53Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RFW6E5RFW6_HUMAN
EF-hand calcium-binding domain-cont...
EFCAB13
37Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7ELL9K7ELL9_HUMAN
EF-hand calcium-binding domain-cont...
EFCAB13
104Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH37876 differs from that shown. Reason: Frameshift at position 342.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_061091279I → V. Corresponds to variant dbSNP:rs55853213Ensembl.1
Natural variantiVAR_035465286Q → H in a breast cancer sample; somatic mutation. 1 Publication1
Natural variantiVAR_031228312V → I1 PublicationCorresponds to variant dbSNP:rs4968318Ensembl.1
Natural variantiVAR_031229617M → V1 PublicationCorresponds to variant dbSNP:rs17855599Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_047187173 – 269ALHKA…TYIDS → G in isoform 2. 1 PublicationAdd BLAST97
Alternative sequenceiVSP_047188880E → G in isoform 2. 1 Publication1
Alternative sequenceiVSP_047189881 – 973Missing in isoform 2. 1 PublicationAdd BLAST93

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC040934 Genomic DNA No translation available.
AC068234 Genomic DNA No translation available.
CH471231 Genomic DNA Translation: EAW57672.1
BC036407 mRNA Translation: AAH36407.1
BC037876 mRNA Translation: AAH37876.1 Frameshift.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS11512.1 [Q8IY85-1]
CCDS56034.1 [Q8IY85-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001182121.1, NM_001195192.1 [Q8IY85-2]
NP_689560.3, NM_152347.4 [Q8IY85-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000331493; ENSP00000332111; ENSG00000178852 [Q8IY85-1]
ENST00000517484; ENSP00000430048; ENSG00000178852 [Q8IY85-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
124989

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:124989

UCSC genome browser

More...
UCSCi
uc002ilm.4 human [Q8IY85-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC040934 Genomic DNA No translation available.
AC068234 Genomic DNA No translation available.
CH471231 Genomic DNA Translation: EAW57672.1
BC036407 mRNA Translation: AAH36407.1
BC037876 mRNA Translation: AAH37876.1 Frameshift.
CCDSiCCDS11512.1 [Q8IY85-1]
CCDS56034.1 [Q8IY85-2]
RefSeqiNP_001182121.1, NM_001195192.1 [Q8IY85-2]
NP_689560.3, NM_152347.4 [Q8IY85-1]

3D structure databases

SMRiQ8IY85
ModBaseiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000332111

PTM databases

iPTMnetiQ8IY85
PhosphoSitePlusiQ8IY85

Polymorphism and mutation databases

BioMutaiEFCAB13
DMDMi134034056

Proteomic databases

PaxDbiQ8IY85
PeptideAtlasiQ8IY85
PRIDEiQ8IY85
ProteomicsDBi32238
71125 [Q8IY85-1]
71126 [Q8IY85-2]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
124989
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000331493; ENSP00000332111; ENSG00000178852 [Q8IY85-1]
ENST00000517484; ENSP00000430048; ENSG00000178852 [Q8IY85-2]
GeneIDi124989
KEGGihsa:124989
UCSCiuc002ilm.4 human [Q8IY85-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
124989
DisGeNETi124989

GeneCards: human genes, protein and diseases

More...
GeneCardsi
EFCAB13
HGNCiHGNC:26864 EFCAB13
HPAiCAB002501
HPA021633
HPA023249
HPA026561
neXtProtiNX_Q8IY85
OpenTargetsiENSG00000178852
PharmGKBiPA142672240

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG0027 Eukaryota
COG5126 LUCA
GeneTreeiENSGT00390000004027
HOGENOMiHOG000111932
InParanoidiQ8IY85
OMAiACKIFSK
OrthoDBi222861at2759
PhylomeDBiQ8IY85
TreeFamiTF337478

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
EFCAB13 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
124989

Protein Ontology

More...
PROi
PR:Q8IY85

Gene expression databases

BgeeiENSG00000178852 Expressed in 106 organ(s), highest expression level in left coronary artery
ExpressionAtlasiQ8IY85 baseline and differential
GenevisibleiQ8IY85 HS

Family and domain databases

InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
SUPFAMiSSF47473 SSF47473, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiEFC13_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8IY85
Secondary accession number(s): G3V128, Q49AG9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: March 20, 2007
Last modified: July 31, 2019
This is version 130 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
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