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Entry version 139 (08 May 2019)
Sequence version 1 (01 Mar 2003)
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Protein

Intraflagellar transport protein 20 homolog

Gene

IFT20

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Part of intraflagellar transport (IFT) particles involved in ciliary process assembly. May play a role in the trafficking of ciliary membrane proteins from the Golgi complex to the cilium (PubMed:16775004). Regulates the platelet-derived growth factor receptor-alpha (PDGFRA) signaling pathway. Required for protein stability of E3 ubiquitin ligases CBL and CBLB that mediate ubiquitination and internalization of PDGFRA for proper feedback inhibition of PDGFRA signaling (PubMed:29237719). Essential for male fertility. Plays an important role in spermatogenesis, particularly spermiogenesis, when germ cells form flagella. May play a role in the transport of flagellar proteins ODF2 and SPAG16 to build sperm flagella and in the removal of redundant sperm cytoplasm (By similarity). Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment (By similarity).By similarity2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • opsin binding Source: Ensembl
  • Rab GTPase binding Source: ParkinsonsUK-UCL

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCilium biogenesis/degradation, Differentiation, Spermatogenesis

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-5620924 Intraflagellar transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Intraflagellar transport protein 20 homolog
Short name:
hIFT20
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:IFT20
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Human Gene Nomenclature Database

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HGNCi
HGNC:30989 IFT20

Online Mendelian Inheritance in Man (OMIM)

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MIMi
614394 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8IY31

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell projection, Cilium, Cytoplasm, Cytoskeleton, Golgi apparatus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000109083

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142671663

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
IFT20

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74728279

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002493031 – 132Intraflagellar transport protein 20 homologAdd BLAST132

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8IY31

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8IY31

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8IY31

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8IY31

PeptideAtlas

More...
PeptideAtlasi
Q8IY31

PRoteomics IDEntifications database

More...
PRIDEi
Q8IY31

ProteomicsDB human proteome resource

More...
ProteomicsDBi
71093
71094 [Q8IY31-2]
71095 [Q8IY31-3]

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
Q8IY31-3 [Q8IY31-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8IY31

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8IY31

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in almost all tissues.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000109083 Expressed in 235 organ(s), highest expression level in testis

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8IY31 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8IY31 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA021376

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the IFT complex B, at least composed of IFT20, IFT22, HSPB11/IFT25, IFT27, IFT46, IFT52, TRAF3IP1/IFT54, IFT57, IFT74, IFT80, IFT81, and IFT88. Interacts directly with IFT57 and KIF3B/Kinesin II subunit (By similarity). Interacts with IFT88 (By similarity). Interacts with CEP83 (PubMed:23530209). Interacts with SPEF2 (via C-terminus) (PubMed:19889948). Interacts with CBL and CBLB (PubMed:29237719).By similarity3 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
124711, 107 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q8IY31

Protein interaction database and analysis system

More...
IntActi
Q8IY31, 68 interactors

Molecular INTeraction database

More...
MINTi
Q8IY31

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000464443

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni70 – 132IFT57-bindingBy similarityAdd BLAST63

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili74 – 114Sequence analysisAdd BLAST41

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410KC8U Eukaryota
ENOG4110P7T LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000003413

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000230527

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8IY31

KEGG Orthology (KO)

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KOi
K16473

Identification of Orthologs from Complete Genome Data

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OMAi
IEADQNE

Database of Orthologous Groups

More...
OrthoDBi
1589590at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8IY31

TreeFam database of animal gene trees

More...
TreeFami
TF319434

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR028172 FT20

The PANTHER Classification System

More...
PANTHERi
PTHR31978 PTHR31978, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF14931 IFT20, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 5 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8IY31-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAKDILGEAG LHFDELNKLR VLDPEVTQQT IELKEECKDF VDKIGQFQKI
60 70 80 90 100
VGGLIELVDQ LAKEAENEKM KAIGARNLLK SIAKQREAQQ QQLQALIAEK
110 120 130
KMQLERYRVE YEALCKVEAE QNEFIDQFIF QK
Length:132
Mass (Da):15,281
Last modified:March 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8C751DE18FEEB30F
GO
Isoform 2 (identifier: Q8IY31-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MTHLLLTATVTPSEQNSSREPGWETAM

Show »
Length:158
Mass (Da):18,120
Checksum:i8CB5C24AC62F22D1
GO
Isoform 3 (identifier: Q8IY31-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     72-132: AIGARNLLKS...EFIDQFIFQK → SLAVSPRLEC...KENAARKVSG

Show »
Length:148
Mass (Da):15,964
Checksum:iC19CC3F33BC56CA8
GO
Isoform 4 (identifier: Q8IY31-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     107-132: YRVEYEALCKVEAEQNEFIDQFIFQK → NELKISLL

Note: No experimental confirmation available.
Show »
Length:114
Mass (Da):12,969
Checksum:i80A74AE1A98303BA
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
J3QR43J3QR43_HUMAN
Intraflagellar transport protein 20...
IFT20
132Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3QRC6J3QRC6_HUMAN
Intraflagellar transport protein 20...
IFT20
141Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087X2B4A0A087X2B4_HUMAN
Intraflagellar transport 20 homolog...
IFT20 hCG_31823
74Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3QRH2J3QRH2_HUMAN
Intraflagellar transport protein 20...
IFT20
71Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3KRU2J3KRU2_HUMAN
Intraflagellar transport protein 20...
IFT20
85Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0203901M → MTHLLLTATVTPSEQNSSRE PGWETAM in isoform 2. 1 Publication1
Alternative sequenceiVSP_02039172 – 132AIGAR…FIFQK → SLAVSPRLECTGAISAHCKL CLSDSSDSPTSPSRVGGTTG HRCSELAQIYSKAERSSTAA TSSPNSRKENAARKVSG in isoform 3. 1 PublicationAdd BLAST61
Alternative sequenceiVSP_046026107 – 132YRVEY…FIFQK → NELKISLL in isoform 4. 1 PublicationAdd BLAST26

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY224601 mRNA Translation: AAP50265.1
BQ639919 mRNA No translation available.
AC002094 Genomic DNA No translation available.
BC002640 mRNA Translation: AAH02640.1
BC038094 mRNA Translation: AAH38094.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS32593.1 [Q8IY31-3]
CCDS58533.1 [Q8IY31-4]
CCDS58534.1 [Q8IY31-1]
CCDS58535.1 [Q8IY31-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001254703.1, NM_001267774.1 [Q8IY31-2]
NP_001254704.1, NM_001267775.1 [Q8IY31-1]
NP_001254705.1, NM_001267776.1 [Q8IY31-1]
NP_001254706.1, NM_001267777.1 [Q8IY31-4]
NP_001254707.1, NM_001267778.1
NP_777547.1, NM_174887.3 [Q8IY31-3]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000357896; ENSP00000350570; ENSG00000109083 [Q8IY31-3]
ENST00000395418; ENSP00000378809; ENSG00000109083 [Q8IY31-1]
ENST00000579419; ENSP00000463322; ENSG00000109083 [Q8IY31-4]
ENST00000585089; ENSP00000464443; ENSG00000109083 [Q8IY31-2]
ENST00000585313; ENSP00000463138; ENSG00000109083 [Q8IY31-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
90410

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:90410

UCSC genome browser

More...
UCSCi
uc002hau.3 human [Q8IY31-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY224601 mRNA Translation: AAP50265.1
BQ639919 mRNA No translation available.
AC002094 Genomic DNA No translation available.
BC002640 mRNA Translation: AAH02640.1
BC038094 mRNA Translation: AAH38094.1
CCDSiCCDS32593.1 [Q8IY31-3]
CCDS58533.1 [Q8IY31-4]
CCDS58534.1 [Q8IY31-1]
CCDS58535.1 [Q8IY31-2]
RefSeqiNP_001254703.1, NM_001267774.1 [Q8IY31-2]
NP_001254704.1, NM_001267775.1 [Q8IY31-1]
NP_001254705.1, NM_001267776.1 [Q8IY31-1]
NP_001254706.1, NM_001267777.1 [Q8IY31-4]
NP_001254707.1, NM_001267778.1
NP_777547.1, NM_174887.3 [Q8IY31-3]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi124711, 107 interactors
CORUMiQ8IY31
IntActiQ8IY31, 68 interactors
MINTiQ8IY31
STRINGi9606.ENSP00000464443

PTM databases

iPTMnetiQ8IY31
PhosphoSitePlusiQ8IY31

Polymorphism and mutation databases

BioMutaiIFT20
DMDMi74728279

Proteomic databases

EPDiQ8IY31
jPOSTiQ8IY31
MaxQBiQ8IY31
PaxDbiQ8IY31
PeptideAtlasiQ8IY31
PRIDEiQ8IY31
ProteomicsDBi71093
71094 [Q8IY31-2]
71095 [Q8IY31-3]
TopDownProteomicsiQ8IY31-3 [Q8IY31-3]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
90410
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000357896; ENSP00000350570; ENSG00000109083 [Q8IY31-3]
ENST00000395418; ENSP00000378809; ENSG00000109083 [Q8IY31-1]
ENST00000579419; ENSP00000463322; ENSG00000109083 [Q8IY31-4]
ENST00000585089; ENSP00000464443; ENSG00000109083 [Q8IY31-2]
ENST00000585313; ENSP00000463138; ENSG00000109083 [Q8IY31-1]
GeneIDi90410
KEGGihsa:90410
UCSCiuc002hau.3 human [Q8IY31-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
90410

GeneCards: human genes, protein and diseases

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GeneCardsi
IFT20
HGNCiHGNC:30989 IFT20
HPAiHPA021376
MIMi614394 gene
neXtProtiNX_Q8IY31
OpenTargetsiENSG00000109083
PharmGKBiPA142671663

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiENOG410KC8U Eukaryota
ENOG4110P7T LUCA
GeneTreeiENSGT00390000003413
HOGENOMiHOG000230527
InParanoidiQ8IY31
KOiK16473
OMAiIEADQNE
OrthoDBi1589590at2759
PhylomeDBiQ8IY31
TreeFamiTF319434

Enzyme and pathway databases

ReactomeiR-HSA-5620924 Intraflagellar transport

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
IFT20 human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
IFT20

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
90410

Protein Ontology

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PROi
PR:Q8IY31

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000109083 Expressed in 235 organ(s), highest expression level in testis
ExpressionAtlasiQ8IY31 baseline and differential
GenevisibleiQ8IY31 HS

Family and domain databases

InterProiView protein in InterPro
IPR028172 FT20
PANTHERiPTHR31978 PTHR31978, 1 hit
PfamiView protein in Pfam
PF14931 IFT20, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiIFT20_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8IY31
Secondary accession number(s): J3QL09, Q5GLZ2, Q9BUG5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 5, 2006
Last sequence update: March 1, 2003
Last modified: May 8, 2019
This is version 139 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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