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Entry version 134 (16 Jan 2019)
Sequence version 3 (19 Oct 2011)
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Protein

C-Maf-inducing protein

Gene

CMIP

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plays a role in T-cell signaling pathway. Isoform 2 may play a role in T-helper 2 (Th2) signaling pathway and seems to represent the first proximal signaling protein that links T-cell receptor-mediated signal to the activation of c-Maf Th2 specific factor.2 Publications

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
C-Maf-inducing protein
Short name:
c-Mip
Alternative name(s):
Truncated c-Maf-inducing protein
Short name:
Tc-Mip
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CMIP
Synonyms:KIAA1694, TCMIP
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 16

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000153815.16

Human Gene Nomenclature Database

More...
HGNCi
HGNC:24319 CMIP

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
610112 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8IY22

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
80790

Open Targets

More...
OpenTargetsi
ENSG00000153815

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
CMIP

Domain mapping of disease mutations (DMDM)

More...
DMDMi
353526341

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003176281 – 773C-Maf-inducing proteinAdd BLAST773

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei349PhosphoserineCombined sources1
Modified residuei377PhosphoserineCombined sources1
Modified residuei382PhosphoserineCombined sources1
Modified residuei660PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8IY22

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8IY22

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8IY22

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8IY22

PeptideAtlas

More...
PeptideAtlasi
Q8IY22

PRoteomics IDEntifications database

More...
PRIDEi
Q8IY22

ProteomicsDB human proteome resource

More...
ProteomicsDBi
71089
71090 [Q8IY22-2]
71091 [Q8IY22-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8IY22

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8IY22

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Isoform 1 is expressed in peripheral blood mononuclear cells and kidney. Lower expression in brain and liver. Expression is down-regulated in activated cells. Isoform 2 is expressed in lymphocyte precursors, however, expression shuts down during maturation and differentiation in thymus and fetal liver.1 Publication

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed in fetal liver.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000153815 Expressed in 198 organ(s), highest expression level in pituitary gland

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8IY22 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8IY22 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA054424
HPA066710

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with FLNA.1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
123313, 11 interactors

Protein interaction database and analysis system

More...
IntActi
Q8IY22, 6 interactors

Molecular INTeraction database

More...
MINTi
Q8IY22

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000446100

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q8IY22

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8IY22

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini54 – 163PHAdd BLAST110
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati663 – 686LRR 1Add BLAST24
Repeati687 – 707LRR 2Add BLAST21
Repeati712 – 732LRR 3Add BLAST21
Repeati736 – 756LRR 4Add BLAST21

Keywords - Domaini

Leucine-rich repeat, Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IJT4 Eukaryota
ENOG410XSJQ LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000018220

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000111809

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG107725

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8IY22

Identification of Orthologs from Complete Genome Data

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OMAi
CLMVSPT

Database of Orthologous Groups

More...
OrthoDBi
355421at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8IY22

TreeFam database of animal gene trees

More...
TreeFami
TF328575

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.80.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR032675 LRR_dom_sf

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8IY22-1) [UniParc]FASTAAdd to basket
Also known as: C-Mip

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MDVTSSSGGG GDPRQIEETK PLLGGDVSAP EGTKMGAVPC RRALLLCNGM
60 70 80 90 100
RYKLLQEGDI QVCVIRHPRT FLSKILTSKF LRRWEPHHLT LADNSLASAT
110 120 130 140 150
PTGYMENSVS YSAIEDVQLL SWENAPKYCL QLTIPGGTVL LQAANSYLRD
160 170 180 190 200
QWFHSLQWKK KIYKYKKVLS NPSRWEVVLK EIRTLVDMAL TSPLQDDSIN
210 220 230 240 250
QAPLEIVSKL LSENTNLTTQ EHENIIVAIA PLLENNHPPP DLCEFFCKHC
260 270 280 290 300
RERPRSMVVI EVFTPVVQRI LKHNMDFGKC PRLRLFTQEY ILALNELNAG
310 320 330 340 350
MEVVKKFIQS MHGPTGHCPH PRVLPNLVAV CLAAIYSCYE EFINSRDNSP
360 370 380 390 400
SLKEIRNGCQ QPCDRKPTLP LRLLHPSPDL VSQEATLSEA RLKSVVVASS
410 420 430 440 450
EIHVEVERTS TAKPALTASA GNDSEPNLID CLMVSPACST MSIELGPQAD
460 470 480 490 500
RTLGCYVEIL KLLSDYDDWR PSLASLLQPI PFPKEALAHE KFTKELKYVI
510 520 530 540 550
QRFAEDPRQE VHSCLLSVRA GKDGWFQLYS PGGVACDDDG ELFASMVHIL
560 570 580 590 600
MGSCYKTKKF LLSLAENKLG PCMLLALRGN QTMVEILCLM LEYNIIDNND
610 620 630 640 650
TQLQIISTLE STDVGKRMYE QLCDRQRELK ELQRKGGPTR LTLPSKSTDA
660 670 680 690 700
DLARLLSSGS FGNLENLSLA FTNVTSACAE HLIKLPSLKQ LNLWSTQFGD
710 720 730 740 750
AGLRLLSEHL TMLQVLNLCE TPVTDAGLLA LSSMKSLCSL NMNSTKLSAD
760 770
TYEDLKAKLP NLKEVDVRYT EAW
Length:773
Mass (Da):86,331
Last modified:October 19, 2011 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD8C25A853A93E9DD
GO
Isoform 2 (identifier: Q8IY22-2) [UniParc]FASTAAdd to basket
Also known as: Tc-Mip

The sequence of this isoform differs from the canonical sequence as follows:
     1-94: Missing.
     95-100: SLASAT → MGQAAE

Show »
Length:679
Mass (Da):76,033
Checksum:i7FC78A2ABE8504CE
GO
Isoform 3 (identifier: Q8IY22-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-153: Missing.
     154-159: HSLQWK → MASVAQ

Note: No experimental confirmation available.
Show »
Length:620
Mass (Da):69,288
Checksum:iF84064C435ADAA62
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A087WU05A0A087WU05_HUMAN
C-Maf-inducing protein
CMIP
586Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WY48A0A087WY48_HUMAN
C-Maf-inducing protein
CMIP
678Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WUL1A0A087WUL1_HUMAN
C-Maf-inducing protein
CMIP
125Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0311081 – 153Missing in isoform 3. 1 PublicationAdd BLAST153
Alternative sequenceiVSP_0311091 – 94Missing in isoform 2. 1 PublicationAdd BLAST94
Alternative sequenceiVSP_03111095 – 100SLASAT → MGQAAE in isoform 2. 1 Publication6
Alternative sequenceiVSP_031111154 – 159HSLQWK → MASVAQ in isoform 3. 1 Publication6

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY172689 mRNA Translation: AAO17720.1
AC092135 Genomic DNA No translation available.
AC092139 Genomic DNA No translation available.
AC099480 Genomic DNA No translation available.
AC099524 Genomic DNA No translation available.
BC038113 mRNA Translation: AAH38113.1
AB051481 mRNA Translation: BAB21785.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS54044.1 [Q8IY22-1]
CCDS54045.1 [Q8IY22-2]

NCBI Reference Sequences

More...
RefSeqi
NP_085132.1, NM_030629.2 [Q8IY22-2]
NP_938204.2, NM_198390.2 [Q8IY22-1]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.594095
Hs.662343

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000398040; ENSP00000381120; ENSG00000153815 [Q8IY22-3]
ENST00000537098; ENSP00000446100; ENSG00000153815 [Q8IY22-1]
ENST00000539778; ENSP00000440401; ENSG00000153815 [Q8IY22-2]

Database of genes from NCBI RefSeq genomes

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GeneIDi
80790

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:80790

UCSC genome browser

More...
UCSCi
uc002fgp.5 human [Q8IY22-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY172689 mRNA Translation: AAO17720.1
AC092135 Genomic DNA No translation available.
AC092139 Genomic DNA No translation available.
AC099480 Genomic DNA No translation available.
AC099524 Genomic DNA No translation available.
BC038113 mRNA Translation: AAH38113.1
AB051481 mRNA Translation: BAB21785.1
CCDSiCCDS54044.1 [Q8IY22-1]
CCDS54045.1 [Q8IY22-2]
RefSeqiNP_085132.1, NM_030629.2 [Q8IY22-2]
NP_938204.2, NM_198390.2 [Q8IY22-1]
UniGeneiHs.594095
Hs.662343

3D structure databases

ProteinModelPortaliQ8IY22
SMRiQ8IY22
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi123313, 11 interactors
IntActiQ8IY22, 6 interactors
MINTiQ8IY22
STRINGi9606.ENSP00000446100

PTM databases

iPTMnetiQ8IY22
PhosphoSitePlusiQ8IY22

Polymorphism and mutation databases

BioMutaiCMIP
DMDMi353526341

Proteomic databases

EPDiQ8IY22
jPOSTiQ8IY22
MaxQBiQ8IY22
PaxDbiQ8IY22
PeptideAtlasiQ8IY22
PRIDEiQ8IY22
ProteomicsDBi71089
71090 [Q8IY22-2]
71091 [Q8IY22-3]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000398040; ENSP00000381120; ENSG00000153815 [Q8IY22-3]
ENST00000537098; ENSP00000446100; ENSG00000153815 [Q8IY22-1]
ENST00000539778; ENSP00000440401; ENSG00000153815 [Q8IY22-2]
GeneIDi80790
KEGGihsa:80790
UCSCiuc002fgp.5 human [Q8IY22-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
80790
DisGeNETi80790
EuPathDBiHostDB:ENSG00000153815.16

GeneCards: human genes, protein and diseases

More...
GeneCardsi
CMIP

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0013273
HGNCiHGNC:24319 CMIP
HPAiHPA054424
HPA066710
MIMi610112 gene
neXtProtiNX_Q8IY22
OpenTargetsiENSG00000153815

Human Unidentified Gene-Encoded large proteins database

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HUGEi
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GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiENOG410IJT4 Eukaryota
ENOG410XSJQ LUCA
GeneTreeiENSGT00390000018220
HOGENOMiHOG000111809
HOVERGENiHBG107725
InParanoidiQ8IY22
OMAiCLMVSPT
OrthoDBi355421at2759
PhylomeDBiQ8IY22
TreeFamiTF328575

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
CMIP human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
80790

Protein Ontology

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PROi
PR:Q8IY22

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000153815 Expressed in 198 organ(s), highest expression level in pituitary gland
ExpressionAtlasiQ8IY22 baseline and differential
GenevisibleiQ8IY22 HS

Family and domain databases

Gene3Di3.80.10.10, 1 hit
InterProiView protein in InterPro
IPR032675 LRR_dom_sf

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCMIP_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8IY22
Secondary accession number(s): Q9C0G9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: October 19, 2011
Last modified: January 16, 2019
This is version 134 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  2. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM
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