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UniProtKB - Q8IXQ9 (ETKMT_HUMAN)

Entry version 143 (25 May 2022)
Sequence version 1 (01 Mar 2003)
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Protein

Electron transfer flavoprotein beta subunit lysine methyltransferase

Gene

ETFBKMT

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Protein-lysine methyltransferase that selectively trimethylates the flavoprotein ETFB in mitochondria (PubMed:25023281, PubMed:25416781).

Thereby, may negatively regulate the function of ETFB in electron transfer from Acyl-CoA dehydrogenases to the main respiratory chain (PubMed:25416781).

2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionMethyltransferase, Transferase

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q8IXQ9

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-8876725, Protein methylation

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		Q8IXQ9

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Electron transfer flavoprotein beta subunit lysine methyltransferase1 Publication (EC:2.1.1.-2 Publications)
Alternative name(s):
ETFB lysine methyltransferase1 Publication
Short name:
ETFB-KMT1 Publication
Protein N-lysine methyltransferase METTL20
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ETFBKMTImported
Synonyms:C12orf72, METTL20
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:28739, ETFBKMT

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		615256, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q8IXQ9

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000139160

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, Mitochondrion

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi121D → A: Loss of lysine methyltransferase activity. 1 Publication1

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000139160

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA164716777

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q8IXQ9, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		ETFBKMT

Domain mapping of disease mutations (DMDM)

More...DMDMi		74759679

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – 38MitochondrionSequence analysisAdd BLAST38
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000031870939 – 262Electron transfer flavoprotein beta subunit lysine methyltransferaseAdd BLAST224

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q8IXQ9

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q8IXQ9

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q8IXQ9

PeptideAtlas

More...PeptideAtlasi		Q8IXQ9

PRoteomics IDEntifications database

More...PRIDEi		Q8IXQ9

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		71049

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q8IXQ9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q8IXQ9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000139160, Expressed in buccal mucosa cell and 146 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q8IXQ9, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q8IXQ9, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000139160, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with HSPD1; this protein may possibly be a methylation substrate.

1 Publication

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		129005, 34 interactors

Protein interaction database and analysis system

More...IntActi		Q8IXQ9, 3 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000350353

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q8IXQ9, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

AlphaFold Protein Structure Database

More...AlphaFoldDBi		Q8IXQ9

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q8IXQ9

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the methyltransferase superfamily. ETFBKMT family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502QUSY, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000162982

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_074455_2_1_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q8IXQ9

Identification of Orthologs from Complete Genome Data

More...OMAi		ILNCELN

Database of Orthologous Groups

More...OrthoDBi		1585716at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q8IXQ9

TreeFam database of animal gene trees

More...TreeFami		TF314934

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.40.50.150, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR029063, SAM-dependent_MTases

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF53335, SSF53335, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q8IXQ9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MALSLGWKAH RNHCGLLLQA LRSSGLLLFP CGQCPWRGAG SFLDPEIKAF 
        60         70         80         90        100
LEENTEVTSS GSLTPEIQLR LLTPRCKFWW ERADLWPHSD PYWAIYWPGG 
       110        120        130        140        150
QALSRYLLDN PDVVRGKSVL DLGSGCGATA IAAKMSGASR ILANDIDPIA 
       160        170        180        190        200
GMAITLNCEL NRLNPFPILI QNILNLEQDK WDLVVLGDMF YDEDLADSLH 
       210        220        230        240        250
QWLKKCFWTY RTRVLIGDPG RPQFSGHSIQ HHLHKVVEYS LLESTRQENS 
       260 
GLTTSTVWGF QP
Length:262
Mass (Da):29,461
Last modified:March 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4A784F2DFA6A4216
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G5EA40G5EA40_HUMAN
Electron transfer flavoprotein beta...
ETFBKMT MGC50559, hCG_39178
114Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F5H481F5H481_HUMAN
Electron transfer flavoprotein beta...
ETFBKMT
72Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK290248 mRNA Translation: BAF82937.1
CH471116 Genomic DNA Translation: EAW88545.1
CH471116 Genomic DNA Translation: EAW88547.1
CH471116 Genomic DNA Translation: EAW88548.1
BC039107 mRNA Translation: AAH39107.1
BC039535 mRNA Translation: AAH39535.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS8724.1

NCBI Reference Sequences

More...RefSeqi		NP_001129335.1, NM_001135863.1
NP_001129336.1, NM_001135864.1
NP_776163.1, NM_173802.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000357721.3; ENSP00000350353.3; ENSG00000139160.13
ENST00000395763.7; ENSP00000379112.3; ENSG00000139160.13
ENST00000412352.6; ENSP00000396123.2; ENSG00000139160.13
ENST00000538463.5; ENSP00000441421.1; ENSG00000139160.13

Database of genes from NCBI RefSeq genomes

More...GeneIDi		254013

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:254013

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000357721.3; ENSP00000350353.3; NM_001135863.2; NP_001129335.1

UCSC genome browser

More...UCSCi		uc001rkl.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK290248 mRNA Translation: BAF82937.1
CH471116 Genomic DNA Translation: EAW88545.1
CH471116 Genomic DNA Translation: EAW88547.1
CH471116 Genomic DNA Translation: EAW88548.1
BC039107 mRNA Translation: AAH39107.1
BC039535 mRNA Translation: AAH39535.1
CCDSiCCDS8724.1
RefSeqiNP_001129335.1, NM_001135863.1
NP_001129336.1, NM_001135864.1
NP_776163.1, NM_173802.3

3D structure databases

AlphaFoldDBiQ8IXQ9
SMRiQ8IXQ9
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi129005, 34 interactors
IntActiQ8IXQ9, 3 interactors
STRINGi9606.ENSP00000350353

PTM databases

iPTMnetiQ8IXQ9
PhosphoSitePlusiQ8IXQ9

Genetic variation databases

BioMutaiETFBKMT
DMDMi74759679

Proteomic databases

EPDiQ8IXQ9
MassIVEiQ8IXQ9
PaxDbiQ8IXQ9
PeptideAtlasiQ8IXQ9
PRIDEiQ8IXQ9
ProteomicsDBi71049

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		24685, 34 antibodies from 14 providers

The DNASU plasmid repository

More...DNASUi		254013

Genome annotation databases

EnsembliENST00000357721.3; ENSP00000350353.3; ENSG00000139160.13
ENST00000395763.7; ENSP00000379112.3; ENSG00000139160.13
ENST00000412352.6; ENSP00000396123.2; ENSG00000139160.13
ENST00000538463.5; ENSP00000441421.1; ENSG00000139160.13
GeneIDi254013
KEGGihsa:254013
MANE-SelectiENST00000357721.3; ENSP00000350353.3; NM_001135863.2; NP_001129335.1
UCSCiuc001rkl.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		254013

GeneCards: human genes, protein and diseases

More...GeneCardsi		ETFBKMT
HGNCiHGNC:28739, ETFBKMT
HPAiENSG00000139160, Low tissue specificity
MIMi615256, gene
neXtProtiNX_Q8IXQ9
OpenTargetsiENSG00000139160
PharmGKBiPA164716777
VEuPathDBiHostDB:ENSG00000139160

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG502QUSY, Eukaryota
GeneTreeiENSGT00940000162982
HOGENOMiCLU_074455_2_1_1
InParanoidiQ8IXQ9
OMAiILNCELN
OrthoDBi1585716at2759
PhylomeDBiQ8IXQ9
TreeFamiTF314934

Enzyme and pathway databases

PathwayCommonsiQ8IXQ9
ReactomeiR-HSA-8876725, Protein methylation
SignaLinkiQ8IXQ9

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		254013, 8 hits in 1065 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		ETFBKMT, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		254013
PharosiQ8IXQ9, Tbio

Protein Ontology

More...PROi		PR:Q8IXQ9
RNActiQ8IXQ9, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000139160, Expressed in buccal mucosa cell and 146 other tissues
ExpressionAtlasiQ8IXQ9, baseline and differential
GenevisibleiQ8IXQ9, HS

Family and domain databases

Gene3Di3.40.50.150, 1 hit
InterProiView protein in InterPro
IPR029063, SAM-dependent_MTases
SUPFAMiSSF53335, SSF53335, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiETKMT_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8IXQ9
Secondary accession number(s): D3DUW3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: March 1, 2003
Last modified: May 25, 2022
This is version 143 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries
  2. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. SIMILARITY comments
    Index of protein domains and families
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