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Entry version 130 (16 Oct 2019)
Sequence version 1 (01 Mar 2003)
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Protein

Nurim

Gene

NRM

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Nurim
Alternative name(s):
Nuclear envelope membrane protein
Nuclear rim protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:NRM
Synonyms:NRM29
ORF Names:UNQ555/PRO1112
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Human Gene Nomenclature Database

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HGNCi
HGNC:8003 NRM

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8IXM6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 4NuclearSequence analysis4
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei5 – 28HelicalSequence analysisAdd BLAST24
Topological domaini29 – 58Perinuclear spaceSequence analysisAdd BLAST30
Transmembranei59 – 80HelicalSequence analysisAdd BLAST22
Topological domaini81 – 97NuclearSequence analysisAdd BLAST17
Transmembranei98 – 114HelicalSequence analysisAdd BLAST17
Topological domaini115 – 133Perinuclear spaceSequence analysisAdd BLAST19
Transmembranei134 – 164HelicalSequence analysisAdd BLAST31
Topological domaini165 – 191NuclearSequence analysisAdd BLAST27
Transmembranei192 – 210HelicalSequence analysisAdd BLAST19
Topological domaini211 – 216Perinuclear spaceSequence analysis6
Transmembranei217 – 234HelicalSequence analysisAdd BLAST18
Topological domaini235 – 262NuclearSequence analysisAdd BLAST28

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
11270

Open Targets

More...
OpenTargetsi
ENSG00000137404

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA31782

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q8IXM6

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
NRM

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74750736

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002993951 – 262NurimAdd BLAST262

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
Q8IXM6

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8IXM6

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q8IXM6

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8IXM6

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8IXM6

PeptideAtlas

More...
PeptideAtlasi
Q8IXM6

PRoteomics IDEntifications database

More...
PRIDEi
Q8IXM6

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
71030 [Q8IXM6-1]
71031 [Q8IXM6-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8IXM6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8IXM6

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q8IXM6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000137404 Expressed in 92 organ(s), highest expression level in myometrium

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8IXM6 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8IXM6 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA072545
HPA073982

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
116427, 11 interactors

Protein interaction database and analysis system

More...
IntActi
Q8IXM6, 50 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000259953

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi67 – 72Poly-Leu6
Compositional biasi139 – 253Leu-richAdd BLAST115

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the nurim family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
ENOG410IVGT Eukaryota
ENOG4111VYI LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000008146

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8IXM6

Identification of Orthologs from Complete Genome Data

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OMAi
APCLWSV

Database of Orthologous Groups

More...
OrthoDBi
1048330at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8IXM6

TreeFam database of animal gene trees

More...
TreeFami
TF324853

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR033580 Nurim-like

The PANTHER Classification System

More...
PANTHERi
PTHR31040 PTHR31040, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8IXM6-1) [UniParc]FASTAAdd to basket
Also known as: a

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAPALLLIPA ALASFILAFG TGVEFVRFTS LRPLLGGIPE SGGPDARQGW
60 70 80 90 100
LAALQDRSIL APLAWDLGLL LLFVGQHSLM AAERVKAWTS RYFGVLQRSL
110 120 130 140 150
YVACTALALQ LVMRYWEPIP KGPVLWEARA EPWATWVPLL CFVLHVISWL
160 170 180 190 200
LIFSILLVFD YAELMGLKQV YYHVLGLGEP LALKSPRALR LFSHLRHPVC
210 220 230 240 250
VELLTVLWVV PTLGTDRLLL AFLLTLYLGL AHGLDQQDLR YLRAQLQRKL
260
HLLSRPQDGE AE
Length:262
Mass (Da):29,379
Last modified:March 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i47ED52384BE6C299
GO
Isoform 2 (identifier: Q8IXM6-2) [UniParc]FASTAAdd to basket
Also known as: b

The sequence of this isoform differs from the canonical sequence as follows:
     110-168: Missing.

Show »
Length:203
Mass (Da):22,397
Checksum:i1BCA26472F9A84BA
GO
Isoform 3 (identifier: Q8IXM6-6) [UniParc]FASTAAdd to basket
Also known as: c

The sequence of this isoform differs from the canonical sequence as follows:
     45-109: DARQGWLAAL...LYVACTALAL → GILPCAGAGR...YPLPGPGSRA
     110-262: Missing.

Show »
Length:109
Mass (Da):10,526
Checksum:iAF1B4FB1FDB23157
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H0Y6T6H0Y6T6_HUMAN
Nurim
NRM
262Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_05431145 – 109DARQG…TALAL → GILPCAGAGRASGPEVSPGS QTLLPPAPPSVCGAADSAVG GAYPGHGPSPPCFPPYPLPG PGSRA in isoform 3. 1 PublicationAdd BLAST65
Alternative sequenceiVSP_054312110 – 262Missing in isoform 3. 1 PublicationAdd BLAST153
Alternative sequenceiVSP_027627110 – 168Missing in isoform 2. 1 PublicationAdd BLAST59

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
JQ798186 mRNA Translation: AFL55648.1
JQ798187 mRNA Translation: AFL55649.1
AY358411 mRNA Translation: AAQ88777.1
AK315190 mRNA Translation: BAG37630.1
AB110935 Genomic DNA Translation: BAD13701.1
AB110936 Genomic DNA Translation: BAD13702.1
AB202096 Genomic DNA Translation: BAE78616.1
AL662797 Genomic DNA No translation available.
AL732442 Genomic DNA No translation available.
AL845353 Genomic DNA No translation available.
BX908728 Genomic DNA No translation available.
CR759873 Genomic DNA No translation available.
CR788240 Genomic DNA No translation available.
CR936878 Genomic DNA No translation available.
CH471081 Genomic DNA Translation: EAX03320.1
BC004509 mRNA Translation: AAH04509.2
BC021260 mRNA Translation: AAH21260.1
BC039865 mRNA Translation: AAH39865.1
AF143676 mRNA Translation: AAD45885.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS4686.1 [Q8IXM6-1]
CCDS59498.1 [Q8IXM6-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001257636.1, NM_001270707.1
NP_001257637.1, NM_001270708.1
NP_001257638.1, NM_001270709.1 [Q8IXM6-2]
NP_001257639.1, NM_001270710.1 [Q8IXM6-6]
NP_009174.1, NM_007243.2 [Q8IXM6-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000259953; ENSP00000259953; ENSG00000137404 [Q8IXM6-1]
ENST00000376420; ENSP00000365602; ENSG00000137404 [Q8IXM6-2]
ENST00000376421; ENSP00000365603; ENSG00000137404 [Q8IXM6-1]
ENST00000383570; ENSP00000373064; ENSG00000206484 [Q8IXM6-2]
ENST00000383571; ENSP00000373065; ENSG00000206484 [Q8IXM6-1]
ENST00000422181; ENSP00000409285; ENSG00000234809 [Q8IXM6-1]
ENST00000422664; ENSP00000394788; ENSG00000228854 [Q8IXM6-2]
ENST00000422747; ENSP00000414927; ENSG00000236843 [Q8IXM6-1]
ENST00000427944; ENSP00000405789; ENSG00000228854 [Q8IXM6-1]
ENST00000431322; ENSP00000398752; ENSG00000228867 [Q8IXM6-1]
ENST00000438502; ENSP00000397755; ENSG00000235773 [Q8IXM6-1]
ENST00000445058; ENSP00000389958; ENSG00000236843 [Q8IXM6-2]
ENST00000449041; ENSP00000399560; ENSG00000228867 [Q8IXM6-2]
ENST00000450138; ENSP00000407111; ENSG00000234809 [Q8IXM6-2]
ENST00000456720; ENSP00000392502; ENSG00000235773 [Q8IXM6-2]
ENST00000610775; ENSP00000481407; ENSG00000228867 [Q8IXM6-1]
ENST00000612190; ENSP00000482593; ENSG00000234809 [Q8IXM6-1]
ENST00000613827; ENSP00000481406; ENSG00000228854 [Q8IXM6-1]
ENST00000617159; ENSP00000478812; ENSG00000236843 [Q8IXM6-1]
ENST00000617220; ENSP00000483875; ENSG00000206484 [Q8IXM6-1]
ENST00000620249; ENSP00000482740; ENSG00000235773 [Q8IXM6-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
11270

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:11270

UCSC genome browser

More...
UCSCi
uc003nrc.4 human [Q8IXM6-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JQ798186 mRNA Translation: AFL55648.1
JQ798187 mRNA Translation: AFL55649.1
AY358411 mRNA Translation: AAQ88777.1
AK315190 mRNA Translation: BAG37630.1
AB110935 Genomic DNA Translation: BAD13701.1
AB110936 Genomic DNA Translation: BAD13702.1
AB202096 Genomic DNA Translation: BAE78616.1
AL662797 Genomic DNA No translation available.
AL732442 Genomic DNA No translation available.
AL845353 Genomic DNA No translation available.
BX908728 Genomic DNA No translation available.
CR759873 Genomic DNA No translation available.
CR788240 Genomic DNA No translation available.
CR936878 Genomic DNA No translation available.
CH471081 Genomic DNA Translation: EAX03320.1
BC004509 mRNA Translation: AAH04509.2
BC021260 mRNA Translation: AAH21260.1
BC039865 mRNA Translation: AAH39865.1
AF143676 mRNA Translation: AAD45885.1
CCDSiCCDS4686.1 [Q8IXM6-1]
CCDS59498.1 [Q8IXM6-2]
RefSeqiNP_001257636.1, NM_001270707.1
NP_001257637.1, NM_001270708.1
NP_001257638.1, NM_001270709.1 [Q8IXM6-2]
NP_001257639.1, NM_001270710.1 [Q8IXM6-6]
NP_009174.1, NM_007243.2 [Q8IXM6-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi116427, 11 interactors
IntActiQ8IXM6, 50 interactors
STRINGi9606.ENSP00000259953

PTM databases

iPTMnetiQ8IXM6
PhosphoSitePlusiQ8IXM6
SwissPalmiQ8IXM6

Polymorphism and mutation databases

BioMutaiNRM
DMDMi74750736

Proteomic databases

EPDiQ8IXM6
jPOSTiQ8IXM6
MassIVEiQ8IXM6
MaxQBiQ8IXM6
PaxDbiQ8IXM6
PeptideAtlasiQ8IXM6
PRIDEiQ8IXM6
ProteomicsDBi71030 [Q8IXM6-1]
71031 [Q8IXM6-2]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
11270

Genome annotation databases

EnsembliENST00000259953; ENSP00000259953; ENSG00000137404 [Q8IXM6-1]
ENST00000376420; ENSP00000365602; ENSG00000137404 [Q8IXM6-2]
ENST00000376421; ENSP00000365603; ENSG00000137404 [Q8IXM6-1]
ENST00000383570; ENSP00000373064; ENSG00000206484 [Q8IXM6-2]
ENST00000383571; ENSP00000373065; ENSG00000206484 [Q8IXM6-1]
ENST00000422181; ENSP00000409285; ENSG00000234809 [Q8IXM6-1]
ENST00000422664; ENSP00000394788; ENSG00000228854 [Q8IXM6-2]
ENST00000422747; ENSP00000414927; ENSG00000236843 [Q8IXM6-1]
ENST00000427944; ENSP00000405789; ENSG00000228854 [Q8IXM6-1]
ENST00000431322; ENSP00000398752; ENSG00000228867 [Q8IXM6-1]
ENST00000438502; ENSP00000397755; ENSG00000235773 [Q8IXM6-1]
ENST00000445058; ENSP00000389958; ENSG00000236843 [Q8IXM6-2]
ENST00000449041; ENSP00000399560; ENSG00000228867 [Q8IXM6-2]
ENST00000450138; ENSP00000407111; ENSG00000234809 [Q8IXM6-2]
ENST00000456720; ENSP00000392502; ENSG00000235773 [Q8IXM6-2]
ENST00000610775; ENSP00000481407; ENSG00000228867 [Q8IXM6-1]
ENST00000612190; ENSP00000482593; ENSG00000234809 [Q8IXM6-1]
ENST00000613827; ENSP00000481406; ENSG00000228854 [Q8IXM6-1]
ENST00000617159; ENSP00000478812; ENSG00000236843 [Q8IXM6-1]
ENST00000617220; ENSP00000483875; ENSG00000206484 [Q8IXM6-1]
ENST00000620249; ENSP00000482740; ENSG00000235773 [Q8IXM6-1]
GeneIDi11270
KEGGihsa:11270
UCSCiuc003nrc.4 human [Q8IXM6-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
11270
DisGeNETi11270

GeneCards: human genes, protein and diseases

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GeneCardsi
NRM
HGNCiHGNC:8003 NRM
HPAiHPA072545
HPA073982
neXtProtiNX_Q8IXM6
OpenTargetsiENSG00000137404
PharmGKBiPA31782

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiENOG410IVGT Eukaryota
ENOG4111VYI LUCA
GeneTreeiENSGT00390000008146
InParanoidiQ8IXM6
OMAiAPCLWSV
OrthoDBi1048330at2759
PhylomeDBiQ8IXM6
TreeFamiTF324853

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
NRM human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
11270
PharosiQ8IXM6

Protein Ontology

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PROi
PR:Q8IXM6

Gene expression databases

BgeeiENSG00000137404 Expressed in 92 organ(s), highest expression level in myometrium
ExpressionAtlasiQ8IXM6 baseline and differential
GenevisibleiQ8IXM6 HS

Family and domain databases

InterProiView protein in InterPro
IPR033580 Nurim-like
PANTHERiPTHR31040 PTHR31040, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNRM_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8IXM6
Secondary accession number(s): B0S7R0
, B0S7R1, I3XIE2, I3XIE3, Q5JP57, Q5JP58, Q5JP59, Q5JP60, Q8WU45, Q9BSX3, Q9UN92
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: March 1, 2003
Last modified: October 16, 2019
This is version 130 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
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