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UniProtKB - Q8IXM2 (BAP18_HUMAN)

Entry version 159 (17 Jun 2020)
Sequence version 1 (01 Mar 2003)
Previous versions | rss
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Protein

Chromatin complexes subunit BAP18

Gene

BAP18

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Component of chromatin complexes such as the MLL1/MLL and NURF complexes.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionChromatin regulator, DNA-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Chromatin complexes subunit BAP18
Alternative name(s):
BPTF-associated protein of 18 kDa
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:BAP18
Synonyms:C17orf49
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...EuPathDBi		HostDB:ENSG00000258315.5

Human Gene Nomenclature Database

More...HGNCi		HGNC:28737 C17orf49

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q8IXM2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000258315

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA142672232

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q8IXM2 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		C17orf49

Domain mapping of disease mutations (DMDM)

More...DMDMi		74759674

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002642511 – 172Chromatin complexes subunit BAP18Add BLAST172

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei96PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q8IXM2

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q8IXM2

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q8IXM2

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q8IXM2

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q8IXM2

PeptideAtlas

More...PeptideAtlasi		Q8IXM2

PRoteomics IDEntifications database

More...PRIDEi		Q8IXM2

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		71027 [Q8IXM2-1]
71028 [Q8IXM2-2]
8467

Consortium for Top Down Proteomics

More...TopDownProteomicsi		Q8IXM2-1 [Q8IXM2-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q8IXM2

MetOSite database of methionine sulfoxide sites

More...MetOSitei		Q8IXM2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q8IXM2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000258315 Expressed in adrenal gland and 91 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q8IXM2 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q8IXM2 HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000258315 Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of some MLL1/MLL complex, at least composed of the core components KMT2A/MLL1, ASH2L, HCFC1/HCF1, WDR5 and RBBP5, as well as the facultative components BAP18, CHD8, E2F6, HSP70, INO80C, KANSL1, LAS1L, MAX, MCRS1, MGA, KAT8/MOF, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9 and TEX10.

Component of the nucleosome-remodeling factor (NURF) complex.

2 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		125903, 32 interactors

CORUM comprehensive resource of mammalian protein complexes

More...CORUMi		Q8IXM2

Database of interacting proteins

More...DIPi		DIP-60552N

Protein interaction database and analysis system

More...IntActi		Q8IXM2, 13 interactors

Molecular INTeraction database

More...MINTi		Q8IXM2

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000448598

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q8IXM2 protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini38 – 86SANTAdd BLAST49

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG4834 Eukaryota
ENOG4111K4E LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00390000014721

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_104449_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q8IXM2

KEGG Orthology (KO)

More...KOi		K23406

Database of Orthologous Groups

More...OrthoDBi		1590112at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q8IXM2

TreeFam database of animal gene trees

More...TreeFami		TF324877

Family and domain databases

Conserved Domains Database

More...CDDi		cd00167 SANT, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR037931 BAP18
IPR009057 Homeobox-like_sf
IPR001005 SANT/Myb

The PANTHER Classification System

More...PANTHERi		PTHR21397:SF2 PTHR21397:SF2, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF46689 SSF46689, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8IXM2-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MTSASTKVGE IFSAAGAAFT KLGELTMQLH PVADSSPAGA KWTETEIEML 
        60         70         80         90        100
RAAVKRFGDD LNHISCVIKE RTVAQIKATV KRKVYEDSGI PLPAESPKKG 
       110        120        130        140        150
PKKVASGVLS PPPAAPPPSS SSVPEAGGPP IKKQKADVTL SALNDSDANS 
       160        170 
DVVDIEGLGE TPPAKKLNFD QA
Length:172
Mass (Da):17,900
Last modified:March 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEED33FA9BD649F19
GO
Isoform 2 (identifier: Q8IXM2-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     40-73: Missing.

Show »
Length:138
Mass (Da):13,958
Checksum:i30D3C4ECF6F6D97A
GO
Isoform 3 (identifier: Q8IXM2-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     172-172: A → DSLTLDSGLLMTSADPPLLSC

Show »
Length:192
Mass (Da):19,961
Checksum:i764AC185E4B868A4
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F8W038F8W038_HUMAN
Chromosome 17 open reading frame 49
C17orf49
157Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8W1H0F8W1H0_HUMAN
Chromosome 17 open reading frame 49
C17orf49
166Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7ES76K7ES76_HUMAN
Chromosome 17 open reading frame 49
C17orf49
23Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_04375440 – 73Missing in isoform 2. 1 PublicationAdd BLAST34
Alternative sequenceiVSP_047095172A → DSLTLDSGLLMTSADPPLLS C in isoform 3. Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
CN280697 mRNA No translation available.
AK295795 mRNA Translation: BAG58615.1
AC040977 Genomic DNA No translation available.
CH471108 Genomic DNA Translation: EAW90278.1
BC040036 mRNA Translation: AAH40036.1
BC040148 mRNA Translation: AAH40148.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS32542.1 [Q8IXM2-1]
CCDS45595.1 [Q8IXM2-3]
CCDS45596.1 [Q8IXM2-2]

NCBI Reference Sequences

More...RefSeqi		NP_001136270.1, NM_001142798.2 [Q8IXM2-3]
NP_001136271.1, NM_001142799.2 [Q8IXM2-2]
NP_777553.1, NM_174893.3 [Q8IXM2-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000439424; ENSP00000411851; ENSG00000258315 [Q8IXM2-1]
ENST00000546495; ENSP00000448598; ENSG00000258315 [Q8IXM2-3]
ENST00000552402; ENSP00000448746; ENSG00000258315 [Q8IXM2-2]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		124944

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:124944

UCSC genome browser

More...UCSCi		uc002ged.4 human [Q8IXM2-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CN280697 mRNA No translation available.
AK295795 mRNA Translation: BAG58615.1
AC040977 Genomic DNA No translation available.
CH471108 Genomic DNA Translation: EAW90278.1
BC040036 mRNA Translation: AAH40036.1
BC040148 mRNA Translation: AAH40148.1
CCDSiCCDS32542.1 [Q8IXM2-1]
CCDS45595.1 [Q8IXM2-3]
CCDS45596.1 [Q8IXM2-2]
RefSeqiNP_001136270.1, NM_001142798.2 [Q8IXM2-3]
NP_001136271.1, NM_001142799.2 [Q8IXM2-2]
NP_777553.1, NM_174893.3 [Q8IXM2-1]

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi125903, 32 interactors
CORUMiQ8IXM2
DIPiDIP-60552N
IntActiQ8IXM2, 13 interactors
MINTiQ8IXM2
STRINGi9606.ENSP00000448598

PTM databases

iPTMnetiQ8IXM2
MetOSiteiQ8IXM2
PhosphoSitePlusiQ8IXM2

Polymorphism and mutation databases

BioMutaiC17orf49
DMDMi74759674

Proteomic databases

EPDiQ8IXM2
jPOSTiQ8IXM2
MassIVEiQ8IXM2
MaxQBiQ8IXM2
PaxDbiQ8IXM2
PeptideAtlasiQ8IXM2
PRIDEiQ8IXM2
ProteomicsDBi71027 [Q8IXM2-1]
71028 [Q8IXM2-2]
8467
TopDownProteomicsiQ8IXM2-1 [Q8IXM2-1]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		61837 100 antibodies

The DNASU plasmid repository

More...DNASUi		124944

Genome annotation databases

EnsembliENST00000439424; ENSP00000411851; ENSG00000258315 [Q8IXM2-1]
ENST00000546495; ENSP00000448598; ENSG00000258315 [Q8IXM2-3]
ENST00000552402; ENSP00000448746; ENSG00000258315 [Q8IXM2-2]
GeneIDi124944
KEGGihsa:124944
UCSCiuc002ged.4 human [Q8IXM2-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		124944
EuPathDBiHostDB:ENSG00000258315.5

GeneCards: human genes, protein and diseases

More...GeneCardsi		C17orf49
HGNCiHGNC:28737 C17orf49
HPAiENSG00000258315 Low tissue specificity
neXtProtiNX_Q8IXM2
OpenTargetsiENSG00000258315
PharmGKBiPA142672232

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG4834 Eukaryota
ENOG4111K4E LUCA
GeneTreeiENSGT00390000014721
HOGENOMiCLU_104449_0_0_1
InParanoidiQ8IXM2
KOiK23406
OrthoDBi1590112at2759
PhylomeDBiQ8IXM2
TreeFamiTF324877

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		124944 179 hits in 789 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		124944
PharosiQ8IXM2 Tdark

Protein Ontology

More...PROi		PR:Q8IXM2
RNActiQ8IXM2 protein

Gene expression databases

BgeeiENSG00000258315 Expressed in adrenal gland and 91 other tissues
ExpressionAtlasiQ8IXM2 baseline and differential
GenevisibleiQ8IXM2 HS

Family and domain databases

CDDicd00167 SANT, 1 hit
InterProiView protein in InterPro
IPR037931 BAP18
IPR009057 Homeobox-like_sf
IPR001005 SANT/Myb
PANTHERiPTHR21397:SF2 PTHR21397:SF2, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiBAP18_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8IXM2
Secondary accession number(s): B4DIV3, C9J4G0, E9PB29
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: March 1, 2003
Last modified: June 17, 2020
This is version 159 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
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