UniProtKB - Q8IXL9 (IQCF2_HUMAN)
Protein
IQ domain-containing protein F2
Gene
IQCF2
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- calmodulin binding Source: GO_Central
Enzyme and pathway databases
PathwayCommonsi | Q8IXL9 |
Names & Taxonomyi
Protein namesi | Recommended name: IQ domain-containing protein F2 |
Gene namesi | Name:IQCF2 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000184345.4 |
HGNCi | HGNC:31815, IQCF2 |
neXtProti | NX_Q8IXL9 |
Pathology & Biotechi
Organism-specific databases
OpenTargetsi | ENSG00000184345 |
PharmGKBi | PA134900355 |
Miscellaneous databases
Pharosi | Q8IXL9, Tdark |
Polymorphism and mutation databases
BioMutai | IQCF2 |
DMDMi | 74728210 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000282559 | 1 – 164 | IQ domain-containing protein F2Add BLAST | 164 |
Proteomic databases
MassIVEi | Q8IXL9 |
PaxDbi | Q8IXL9 |
PeptideAtlasi | Q8IXL9 |
PRIDEi | Q8IXL9 |
ProteomicsDBi | 71026 |
PTM databases
iPTMneti | Q8IXL9 |
PhosphoSitePlusi | Q8IXL9 |
Expressioni
Gene expression databases
Bgeei | ENSG00000184345, Expressed in testis and 39 other tissues |
Genevisiblei | Q8IXL9, HS |
Organism-specific databases
HPAi | ENSG00000184345, Tissue enriched (testis) |
Interactioni
Binary interactionsi
Q8IXL9
With | #Exp. | IntAct |
---|---|---|
LONRF1 [Q17RB8] | 3 | EBI-10238842,EBI-2341787 |
GO - Molecular functioni
- calmodulin binding Source: GO_Central
Protein-protein interaction databases
BioGRIDi | 132986, 12 interactors |
IntActi | Q8IXL9, 1 interactor |
STRINGi | 9606.ENSP00000329904 |
Miscellaneous databases
RNActi | Q8IXL9, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 43 – 72 | IQ 1PROSITE-ProRule annotationAdd BLAST | 30 | |
Domaini | 99 – 128 | IQ 2PROSITE-ProRule annotationAdd BLAST | 30 |
Keywords - Domaini
RepeatPhylogenomic databases
eggNOGi | ENOG502SR3N, Eukaryota |
GeneTreei | ENSGT00390000004641 |
HOGENOMi | CLU_114989_2_0_1 |
InParanoidi | Q8IXL9 |
OMAi | YVIQCHW |
OrthoDBi | 1354510at2759 |
PhylomeDBi | Q8IXL9 |
TreeFami | TF337908 |
Family and domain databases
InterProi | View protein in InterPro IPR000048, IQ_motif_EF-hand-BS IPR039887, IQCF |
PANTHERi | PTHR21633, PTHR21633, 1 hit |
Pfami | View protein in Pfam PF00612, IQ, 3 hits |
SMARTi | View protein in SMART SM00015, IQ, 3 hits |
PROSITEi | View protein in PROSITE PS50096, IQ, 2 hits |
i Sequence
Sequence statusi: Complete.
Q8IXL9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MRVRFCTKGN LILVIIEDVE ESIEWKTLQK KKQQKIKEKL RIRTKAAVKI
60 70 80 90 100
QAWWRGTLVR RTLLHAALRA WIIQCWWRMT LSRVLEKKRQ AALIAYATRE
110 120 130 140 150
RAVIKLQSLV RMWRVRWRYC QVLNAIYIIQ GHWQCHNCQT CALLQGHCVV
160
TATHLQFHIE IINS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC040047 mRNA Translation: AAH40047.1 |
CCDSi | CCDS2835.1 |
RefSeqi | NP_982248.1, NM_203424.1 |
Genome annotation databases
Ensembli | ENST00000333127; ENSP00000329904; ENSG00000184345 |
GeneIDi | 389123 |
KEGGi | hsa:389123 |
UCSCi | uc003dbt.2, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC040047 mRNA Translation: AAH40047.1 |
CCDSi | CCDS2835.1 |
RefSeqi | NP_982248.1, NM_203424.1 |
3D structure databases
SMRi | Q8IXL9 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 132986, 12 interactors |
IntActi | Q8IXL9, 1 interactor |
STRINGi | 9606.ENSP00000329904 |
PTM databases
iPTMneti | Q8IXL9 |
PhosphoSitePlusi | Q8IXL9 |
Polymorphism and mutation databases
BioMutai | IQCF2 |
DMDMi | 74728210 |
Proteomic databases
MassIVEi | Q8IXL9 |
PaxDbi | Q8IXL9 |
PeptideAtlasi | Q8IXL9 |
PRIDEi | Q8IXL9 |
ProteomicsDBi | 71026 |
Protocols and materials databases
Antibodypediai | 76253, 29 antibodies |
DNASUi | 389123 |
Genome annotation databases
Ensembli | ENST00000333127; ENSP00000329904; ENSG00000184345 |
GeneIDi | 389123 |
KEGGi | hsa:389123 |
UCSCi | uc003dbt.2, human |
Organism-specific databases
CTDi | 389123 |
EuPathDBi | HostDB:ENSG00000184345.4 |
GeneCardsi | IQCF2 |
HGNCi | HGNC:31815, IQCF2 |
HPAi | ENSG00000184345, Tissue enriched (testis) |
neXtProti | NX_Q8IXL9 |
OpenTargetsi | ENSG00000184345 |
PharmGKBi | PA134900355 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG502SR3N, Eukaryota |
GeneTreei | ENSGT00390000004641 |
HOGENOMi | CLU_114989_2_0_1 |
InParanoidi | Q8IXL9 |
OMAi | YVIQCHW |
OrthoDBi | 1354510at2759 |
PhylomeDBi | Q8IXL9 |
TreeFami | TF337908 |
Enzyme and pathway databases
PathwayCommonsi | Q8IXL9 |
Miscellaneous databases
BioGRID-ORCSi | 389123, 5 hits in 836 CRISPR screens |
GenomeRNAii | 389123 |
Pharosi | Q8IXL9, Tdark |
PROi | PR:Q8IXL9 |
RNActi | Q8IXL9, protein |
Gene expression databases
Bgeei | ENSG00000184345, Expressed in testis and 39 other tissues |
Genevisiblei | Q8IXL9, HS |
Family and domain databases
InterProi | View protein in InterPro IPR000048, IQ_motif_EF-hand-BS IPR039887, IQCF |
PANTHERi | PTHR21633, PTHR21633, 1 hit |
Pfami | View protein in Pfam PF00612, IQ, 3 hits |
SMARTi | View protein in SMART SM00015, IQ, 3 hits |
PROSITEi | View protein in PROSITE PS50096, IQ, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | IQCF2_HUMAN | |
Accessioni | Q8IXL9Primary (citable) accession number: Q8IXL9 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 3, 2007 |
Last sequence update: | March 1, 2003 | |
Last modified: | December 2, 2020 | |
This is version 105 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome 3
Human chromosome 3: entries, gene names and cross-references to MIM