ELK4, ETS-domain protein (SRF accessory protein 1)

Functionⁱ

GO - Molecular functionⁱ

DNA-binding transcription factor activity Source: InterPro
sequence-specific DNA binding Source: InterPro

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	DNA-bindingUniRule annotationSAAS annotation

Molecular function

DNA-bindingUniRule annotationSAAS annotation

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: ELK4, ETS-domain protein (SRF accessory protein 1)Imported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Keywords - Cellular componentⁱ

NucleusUniRule annotationSAAS annotation

Pathology & Biotechⁱ

Organism-specific databases

PharmGKBⁱ	PA27753

PharmGKBⁱ

PA27753

PTM / Processingⁱ

Proteomic databases

PeptideAtlas More...PeptideAtlasⁱ	Q8IXL1
PRIDEⁱ	Q8IXL1

Expressionⁱ

Gene expression databases

Genevisibleⁱ	Q8IXL1 HS

Genevisibleⁱ

Q8IXL1 HS

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q8IXL1
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	95 – 175	ETSInterPro annotationAdd BLAST		81

Sequence similaritiesⁱ

Belongs to the ETS family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGⁱ	KOG3806 Eukaryota ENOG410Z0ZF LUCA
HOGENOMⁱ	HOG000237332
HOVERGENⁱ	HBG004344
KEGG Orthology (KO) More...KOⁱ	K04376
PhylomeDBⁱ	Q8IXL1

Family and domain databases

Gene3Dⁱ	1.10.10.10, 1 hit
InterProⁱ	View protein in InterPro IPR000418 Ets_dom IPR036388 WH-like_DNA-bd_sf IPR036390 WH_DNA-bd_sf
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00178 Ets, 1 hit
PRINTSⁱ	PR00454 ETSDOMAIN
SMARTⁱ	View protein in SMART SM00413 ETS, 1 hit
SUPFAMⁱ	SSF46785 SSF46785, 1 hit
PROSITEⁱ	View protein in PROSITE PS00345 ETS_DOMAIN_1, 1 hit PS00346 ETS_DOMAIN_2, 1 hit PS50061 ETS_DOMAIN_3, 1 hit

Sequenceⁱ

Sequence statusⁱ: Fragment.

Q8IXL1-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
RPQDPRRRCR VRGRGGRGAR SRGGGRCGRL RAPGGLGLAA AAFYGSAAGV 
        60         70         80         90        100
AAAAAPSSSF QREEEAEGGE AHRVRGGDRG GAPRAASLIA MDSAITLWQF 
       110        120        130        140        150
LLQLLQKPQN KHMICWTSND GQFKLLQAEE VARLWGIRKN KPNMNYDKLS 
       160        170        180        190        200
RALRYYYVKN IIKKVNGQKF VYKFVSYPEI LNMDPMTVGR IEGDCESLNF 
       210        220        230        240        250
SEVSSSSKDV ENGGKDKPPQ PGAKTSSRND YIHSGLYSSF TLNSLNSSNV 
       260        270        280        290        300
KLFKLIKTEN PAEKLAEKKS PQEPTPSVIK FVTTPSKKPP VEPVAATISI 
       310        320        330        340        350
GPSISPSSEE TIQALETLVS PKLPSLEAPT SASNVMTAFA TTPPISSIPP 
       360        370        380        390        400
LQEPPRTPSP PLSSHPDIDT DIDSVASQPM ELPENLSLEP KDQDSVLLEK 
       410        420        430        440        450
DKVNNSSRSK KPKGLELAPT LVITSSDPSP LGILSPSLPT ASLTPAFFSQ 
       460        470        480        490        500
TPIILTPSPL LSSIHFWSTL SPVAPLSPAR LQGANTLFQF PSVLNSHGPF 
       510        520 
TLSGLDGPST PGPFSPDLQK T

Length:521

Mass (Da):55,950

Last modified:March 1, 2003 - v1

Checksum:ⁱA048481E4C8E2FCF

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Non-terminal residueⁱ	1	Imported		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC040145 mRNA Translation: AAH40145.1
NCBI Reference Sequences More...RefSeqⁱ	NP_001964.2, NM_001973.3 NP_068567.1, NM_021795.2
UniGeneⁱ	Hs.497520 Hs.602654

Genome annotation databases

GeneIDⁱ	2005
KEGGⁱ	hsa:2005

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q8IXL1	ETS domain-containing protein Elk-4	)	HUMAN		431	UniRef100_P28324
ELK4 isoform 4 (Fragment)		PANTR		144
ETS domain-containing protein Elk-4 (Fragment)		HUMAN		144
ELK4, ETS-domain protein (SRF accessory protein 1), isoform CRA_b		HUMAN		431

Protein	Similar proteins		Species	Score	Length	Source
Q8IXL1	ETS domain-containing protein Elk-4	)	HUMAN		431	UniRef90_P28324
ELK4 isoform 4 (Fragment)		PANTR		144
ELK4, ETS transcription factor		SAIBB		453
ETS domain-containing protein Elk-4 (Fragment)		wild yak		435
Uncharacterized protein		OTOGA		432
+45

Protein	Similar proteins		Species	Score	Length	Source
Q8IXL1	ETS domain-containing protein Elk-4	)	HUMAN		431	UniRef50_P28324
ELK4 isoform 4 (Fragment)		PANTR		144
ELK4, ETS transcription factor		SAIBB		453
ETS domain-containing protein Elk-4 (Fragment)		wild yak		435
ETS domain-containing protein Elk-4 isoform X3		TURTR		432
+152

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC040145 mRNA Translation: AAH40145.1
RefSeqⁱ	NP_001964.2, NM_001973.3 NP_068567.1, NM_021795.2
UniGeneⁱ	Hs.497520 Hs.602654

3D structure databases

ProteinModelPortalⁱ	Q8IXL1
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

PeptideAtlasⁱ	Q8IXL1
PRIDEⁱ	Q8IXL1

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	2005
Structural Biology Knowledgebase	Search...

Genome annotation databases

GeneIDⁱ	2005
KEGGⁱ	hsa:2005

Organism-specific databases

CTDⁱ	2005
PharmGKBⁱ	PA27753

Phylogenomic databases

eggNOGⁱ	KOG3806 Eukaryota ENOG410Z0ZF LUCA
HOGENOMⁱ	HOG000237332
HOVERGENⁱ	HBG004344
KOⁱ	K04376
PhylomeDBⁱ	Q8IXL1

Miscellaneous databases

GenomeRNAiⁱ	2005

GenomeRNAiⁱ

2005

Gene expression databases

Genevisibleⁱ	Q8IXL1 HS

Genevisibleⁱ

Q8IXL1 HS

Family and domain databases

Gene3Dⁱ	1.10.10.10, 1 hit
InterProⁱ	View protein in InterPro IPR000418 Ets_dom IPR036388 WH-like_DNA-bd_sf IPR036390 WH_DNA-bd_sf
Pfamⁱ	View protein in Pfam PF00178 Ets, 1 hit
PRINTSⁱ	PR00454 ETSDOMAIN
SMARTⁱ	View protein in SMART SM00413 ETS, 1 hit
SUPFAMⁱ	SSF46785 SSF46785, 1 hit
PROSITEⁱ	View protein in PROSITE PS00345 ETS_DOMAIN_1, 1 hit PS00346 ETS_DOMAIN_2, 1 hit PS50061 ETS_DOMAIN_3, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q8IXL1_HUMAN
Accessionⁱ	Q8IXL1Primary (citable) accession number: Q8IXL1
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	March 1, 2003
	Last sequence update:	March 1, 2003
	Last modified:	September 12, 2018
	This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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UniProtKB - Q8IXL1 (Q8IXL1_HUMAN)

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ELK4, ETS-domain protein (SRF accessory protein 1)

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Nucleus

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

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Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ