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Entry version 112 (18 Sep 2019)
Sequence version 2 (05 May 2009)
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Protein

Protein NOXP20

Gene

FAM114A1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May play a role in neuronal cell development.By similarity

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein NOXP20
Alternative name(s):
Nervous system overexpressed protein 20
Protein FAM114A1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FAM114A1
Synonyms:NOXP20
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:25087 FAM114A1

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8IWE2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
92689

Open Targets

More...
OpenTargetsi
ENSG00000197712

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162385681

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q8IWE2

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
FAM114A1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
229462912

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002745611 – 563Protein NOXP20Add BLAST563

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei120PhosphoserineCombined sources1
Modified residuei185PhosphothreonineCombined sources1
Modified residuei189PhosphothreonineCombined sources1
Modified residuei196PhosphoserineCombined sources1
Modified residuei199PhosphothreonineBy similarity1
Modified residuei202PhosphoserineCombined sources1
Modified residuei261PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8IWE2

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8IWE2

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q8IWE2

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8IWE2

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8IWE2

PeptideAtlas

More...
PeptideAtlasi
Q8IWE2

PRoteomics IDEntifications database

More...
PRIDEi
Q8IWE2

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
66587
70848 [Q8IWE2-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8IWE2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8IWE2

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q8IWE2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000197712 Expressed in 229 organ(s), highest expression level in parotid gland

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8IWE2 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8IWE2 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA067948
HPA069104
HPA069701

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
124967, 17 interactors

Protein interaction database and analysis system

More...
IntActi
Q8IWE2, 10 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000351740

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili343 – 367Sequence analysisAdd BLAST25

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the FAM114 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IHQB Eukaryota
ENOG411029H LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000010054

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000059573

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8IWE2

Identification of Orthologs from Complete Genome Data

More...
OMAi
TAMCKEV

Database of Orthologous Groups

More...
OrthoDBi
947469at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8IWE2

TreeFam database of animal gene trees

More...
TreeFami
TF324360

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR007998 DUF719

The PANTHER Classification System

More...
PANTHERi
PTHR12842 PTHR12842, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05334 DUF719, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8IWE2-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSDDAGDTLA TGDKAEVTEM PNSDSLPEDA EVHCDSAAVS HEPTPADPRG
60 70 80 90 100
EGHENAAVQG AGAAAIGPPV QPQDANALEP PLNGDVTEDT LAECIDSVSL
110 120 130 140 150
EAEPRSEIPL QEQNYLAVDS PPSGGGWAGW GSWGKSLLSS ASATVGHGLT
160 170 180 190 200
AVKEKAGATL RIHGVNSGSS EGAQPNTENG VPEITDAATD QGPAESPPTS
210 220 230 240 250
PSSASRGMLS AITNVVQNTG KSVLTGGLDA LEFIGKKTMN VLAESDPGFK
260 270 280 290 300
RTKTLMERTV SLSQMLREAK EKEKQRLAQQ LTMERTAHYG MLFDEYQGLS
310 320 330 340 350
HLEALEILSN ESESKVQSFL ASLDGEKLEL LKNDLISIKD IFAAKELENE
360 370 380 390 400
ENQEEQGLEE KGEEFARMLT ELLFELHVAA TPDKLNKAMK RAHDWVEEDQ
410 420 430 440 450
TVVSVDVAKV SEEETKKEEK EEKSQDPQED KKEEKKTKTI EEVYMSSIES
460 470 480 490 500
LAEVTARCIE QLHKVAELIL HGQEEEKPAQ DQAKVLIKLT TAMCNEVASL
510 520 530 540 550
SKKFTNSLTT VGSNKKAEVL NPMISSVLLE GCNSTTYIQD AFQLLLPVLQ
560
VSHIQTSCLK AQP
Length:563
Mass (Da):60,742
Last modified:May 5, 2009 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i318AC32240D3786F
GO
Isoform 2 (identifier: Q8IWE2-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-207: Missing.

Note: No experimental confirmation available.
Show »
Length:356
Mass (Da):39,993
Checksum:i6C57787792550616
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D6R9C9D6R9C9_HUMAN
Protein NOXP20
FAM114A1
133Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_05382340S → L. Corresponds to variant dbSNP:rs34137542Ensembl.1
Natural variantiVAR_03032084G → R1 PublicationCorresponds to variant dbSNP:rs11096964Ensembl.1
Natural variantiVAR_030321116L → PCombined sources1 PublicationCorresponds to variant dbSNP:rs11555334Ensembl.1
Natural variantiVAR_030322201P → L. Corresponds to variant dbSNP:rs430296Ensembl.1
Natural variantiVAR_030323367R → H. Corresponds to variant dbSNP:rs2306923Ensembl.1
Natural variantiVAR_030324443V → I. Corresponds to variant dbSNP:rs17429619Ensembl.1
Natural variantiVAR_053824446S → L. Corresponds to variant dbSNP:rs36058104Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0564661 – 207Missing in isoform 2. 1 PublicationAdd BLAST207

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK292831 mRNA Translation: BAF85520.1
BX640862 mRNA Translation: CAE45923.1
AC108044 Genomic DNA No translation available.
BC001096 mRNA Translation: AAH01096.2
BC040452 mRNA Translation: AAH40452.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS3447.1 [Q8IWE2-1]
CCDS82916.1 [Q8IWE2-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001317693.1, NM_001330764.1 [Q8IWE2-2]
NP_612398.2, NM_138389.3 [Q8IWE2-1]
XP_005262729.1, XM_005262672.2 [Q8IWE2-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000358869; ENSP00000351740; ENSG00000197712 [Q8IWE2-1]
ENST00000515037; ENSP00000424115; ENSG00000197712 [Q8IWE2-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
92689

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:92689

UCSC genome browser

More...
UCSCi
uc003gtn.4 human [Q8IWE2-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK292831 mRNA Translation: BAF85520.1
BX640862 mRNA Translation: CAE45923.1
AC108044 Genomic DNA No translation available.
BC001096 mRNA Translation: AAH01096.2
BC040452 mRNA Translation: AAH40452.1
CCDSiCCDS3447.1 [Q8IWE2-1]
CCDS82916.1 [Q8IWE2-2]
RefSeqiNP_001317693.1, NM_001330764.1 [Q8IWE2-2]
NP_612398.2, NM_138389.3 [Q8IWE2-1]
XP_005262729.1, XM_005262672.2 [Q8IWE2-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi124967, 17 interactors
IntActiQ8IWE2, 10 interactors
STRINGi9606.ENSP00000351740

PTM databases

iPTMnetiQ8IWE2
PhosphoSitePlusiQ8IWE2
SwissPalmiQ8IWE2

Polymorphism and mutation databases

BioMutaiFAM114A1
DMDMi229462912

Proteomic databases

EPDiQ8IWE2
jPOSTiQ8IWE2
MassIVEiQ8IWE2
MaxQBiQ8IWE2
PaxDbiQ8IWE2
PeptideAtlasiQ8IWE2
PRIDEiQ8IWE2
ProteomicsDBi66587
70848 [Q8IWE2-1]

Genome annotation databases

EnsembliENST00000358869; ENSP00000351740; ENSG00000197712 [Q8IWE2-1]
ENST00000515037; ENSP00000424115; ENSG00000197712 [Q8IWE2-2]
GeneIDi92689
KEGGihsa:92689
UCSCiuc003gtn.4 human [Q8IWE2-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
92689
DisGeNETi92689

GeneCards: human genes, protein and diseases

More...
GeneCardsi
FAM114A1
HGNCiHGNC:25087 FAM114A1
HPAiHPA067948
HPA069104
HPA069701
neXtProtiNX_Q8IWE2
OpenTargetsiENSG00000197712
PharmGKBiPA162385681

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IHQB Eukaryota
ENOG411029H LUCA
GeneTreeiENSGT00390000010054
HOGENOMiHOG000059573
InParanoidiQ8IWE2
OMAiTAMCKEV
OrthoDBi947469at2759
PhylomeDBiQ8IWE2
TreeFamiTF324360

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
FAM114A1 human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
FAM114A1

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
92689
PharosiQ8IWE2

Protein Ontology

More...
PROi
PR:Q8IWE2

Gene expression databases

BgeeiENSG00000197712 Expressed in 229 organ(s), highest expression level in parotid gland
ExpressionAtlasiQ8IWE2 baseline and differential
GenevisibleiQ8IWE2 HS

Family and domain databases

InterProiView protein in InterPro
IPR007998 DUF719
PANTHERiPTHR12842 PTHR12842, 1 hit
PfamiView protein in Pfam
PF05334 DUF719, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNXP20_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8IWE2
Secondary accession number(s): A8K9W6, Q6MZV4, Q9BVL6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: May 5, 2009
Last modified: September 18, 2019
This is version 112 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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