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Entry version 129 (07 Oct 2020)
Sequence version 2 (10 Jul 2007)
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Protein

Solute carrier family 41 member 1

Gene

SLC41A1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Acts as a magnesium transporter that is responsive to magnesium balance.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processIon transport, Transport
LigandMagnesium

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q8IVJ1

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-425410, Metal ion SLC transporters

Protein family/group databases

Transport Classification Database

More...
TCDBi
1.A.26.2.1, the mg(2+) transporter-e (mgte) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Solute carrier family 41 member 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SLC41A1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000133065.10

Human Gene Nomenclature Database

More...
HGNCi
HGNC:19429, SLC41A1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
610801, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8IVJ1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei102 – 122HelicalSequence analysisAdd BLAST21
Transmembranei185 – 205HelicalSequence analysisAdd BLAST21
Transmembranei222 – 242HelicalSequence analysisAdd BLAST21
Transmembranei257 – 277HelicalSequence analysisAdd BLAST21
Transmembranei286 – 306HelicalSequence analysisAdd BLAST21
Transmembranei316 – 336HelicalSequence analysisAdd BLAST21
Transmembranei346 – 366HelicalSequence analysisAdd BLAST21
Transmembranei411 – 431HelicalSequence analysisAdd BLAST21
Transmembranei439 – 459HelicalSequence analysisAdd BLAST21
Transmembranei484 – 504HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
254428

Open Targets

More...
OpenTargetsi
ENSG00000133065

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134889327

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q8IVJ1, Tbio

Chemistry databases

Drug and drug target database

More...
DrugBanki
DB14513, Magnesium

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
SLC41A1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
152112285

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002951111 – 513Solute carrier family 41 member 1Add BLAST513

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8IVJ1

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8IVJ1

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q8IVJ1

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8IVJ1

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8IVJ1

PeptideAtlas

More...
PeptideAtlasi
Q8IVJ1

PRoteomics IDEntifications database

More...
PRIDEi
Q8IVJ1

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
70715

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8IVJ1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8IVJ1

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q8IVJ1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Highest expression levels in heart and testis, slightly less in skeletal muscles, prostate, adrenal gland and thyroid, and weakest in the hematopoietic tissues bones marrow, lymph node, thymus and spleen.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000133065, Expressed in left ventricle myocardium and 204 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8IVJ1, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8IVJ1, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000133065, Tissue enhanced (heart muscle, pancreas)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
129036, 37 interactors

Protein interaction database and analysis system

More...
IntActi
Q8IVJ1, 32 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000356105

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8IVJ1, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SLC41A transporter family.Curated

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3788, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183042

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_018207_3_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8IVJ1

KEGG Orthology (KO)

More...
KOi
K15122

Identification of Orthologs from Complete Genome Data

More...
OMAi
ELIMIIP

Database of Orthologous Groups

More...
OrthoDBi
1059294at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8IVJ1

TreeFam database of animal gene trees

More...
TreeFami
TF313647

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006667, SLC41_membr_dom
IPR036739, SLC41_membr_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01769, MgtE, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF161093, SSF161093, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q8IVJ1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSKPEPKDV HQLNGTGPSA SPCSSDGPGR EPLAGTSEFL GPDGAGVEVV
60 70 80 90 100
IESRANAKGV REEDALLENG SQSNESDDVS TDRGPAPPSP LKETSFSIGL
110 120 130 140 150
QVLFPFLLAG FGTVAAGMVL DIVQHWEVFQ KVTEVFILVP ALLGLKGNLE
160 170 180 190 200
MTLASRLSTA ANIGHMDTPK ELWRMITGNM ALIQVQATVV GFLASIAAVV
210 220 230 240 250
FGWIPDGHFS IPHAFLLCAS SVATAFIASL VLGMIMIGVI IGSRKIGINP
260 270 280 290 300
DNVATPIAAS LGDLITLALL SGISWGLYLE LNHWRYIYPL VCAFFVALLP
310 320 330 340 350
VWVVLARRSP ATREVLYSGW EPVIIAMAIS SVGGLILDKT VSDPNFAGMA
360 370 380 390 400
VFTPVINGVG GNLVAVQASR ISTFLHMNGM PGENSEQAPR RCPSPCTTFF
410 420 430 440 450
SPDVNSRSAR VLFLLVVPGH LVFLYTISCM QGGHTTLTLI FIIFYMTAAL
460 470 480 490 500
LQVLILLYIA DWMVHWMWGR GLDPDNFSIP YLTALGDLLG TGLLALSFHV
510
LWLIGDRDTD VGD
Length:513
Mass (Da):54,901
Last modified:July 10, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2B6676F9C3AF6136
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti3S → P in CAH56135 (PubMed:17974005).Curated1
Sequence conflicti196I → T in CAH56213 (PubMed:17974005).Curated1
Sequence conflicti204I → V in CAH56213 (PubMed:17974005).Curated1
Sequence conflicti207G → D in CAH56135 (PubMed:17974005).Curated1
Sequence conflicti217L → P in CAH56135 (PubMed:17974005).Curated1
Sequence conflicti272 – 275GISW → ASAG in CAD58404 (PubMed:12810078).Curated4
Sequence conflicti365A → T in CAE46028 (PubMed:17974005).Curated1
Sequence conflicti416V → A in CAD58404 (PubMed:12810078).Curated1
Sequence conflicti464V → A in CAH56135 (PubMed:17974005).Curated1
Sequence conflicti511V → A in CAH56135 (PubMed:17974005).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AJ514402 mRNA Translation: CAD58404.1
AL831974 mRNA Translation: CAH56217.1
AL832001 mRNA Translation: CAH56211.1
AL832362 mRNA Translation: CAH56213.1
BX641054 mRNA Translation: CAE46028.1
BX648979 mRNA Translation: CAH56135.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS30988.1

NCBI Reference Sequences

More...
RefSeqi
NP_776253.3, NM_173854.5
XP_005245126.1, XM_005245069.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000367137; ENSP00000356105; ENSG00000133065

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
254428

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:254428

UCSC genome browser

More...
UCSCi
uc001hdh.2, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ514402 mRNA Translation: CAD58404.1
AL831974 mRNA Translation: CAH56217.1
AL832001 mRNA Translation: CAH56211.1
AL832362 mRNA Translation: CAH56213.1
BX641054 mRNA Translation: CAE46028.1
BX648979 mRNA Translation: CAH56135.1
CCDSiCCDS30988.1
RefSeqiNP_776253.3, NM_173854.5
XP_005245126.1, XM_005245069.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi129036, 37 interactors
IntActiQ8IVJ1, 32 interactors
STRINGi9606.ENSP00000356105

Chemistry databases

DrugBankiDB14513, Magnesium

Protein family/group databases

TCDBi1.A.26.2.1, the mg(2+) transporter-e (mgte) family

PTM databases

iPTMnetiQ8IVJ1
PhosphoSitePlusiQ8IVJ1
SwissPalmiQ8IVJ1

Polymorphism and mutation databases

BioMutaiSLC41A1
DMDMi152112285

Proteomic databases

EPDiQ8IVJ1
jPOSTiQ8IVJ1
MassIVEiQ8IVJ1
MaxQBiQ8IVJ1
PaxDbiQ8IVJ1
PeptideAtlasiQ8IVJ1
PRIDEiQ8IVJ1
ProteomicsDBi70715

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
2794, 39 antibodies

Genome annotation databases

EnsembliENST00000367137; ENSP00000356105; ENSG00000133065
GeneIDi254428
KEGGihsa:254428
UCSCiuc001hdh.2, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
254428
DisGeNETi254428
EuPathDBiHostDB:ENSG00000133065.10

GeneCards: human genes, protein and diseases

More...
GeneCardsi
SLC41A1
HGNCiHGNC:19429, SLC41A1
HPAiENSG00000133065, Tissue enhanced (heart muscle, pancreas)
MIMi610801, gene
neXtProtiNX_Q8IVJ1
OpenTargetsiENSG00000133065
PharmGKBiPA134889327

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3788, Eukaryota
GeneTreeiENSGT00950000183042
HOGENOMiCLU_018207_3_1_1
InParanoidiQ8IVJ1
KOiK15122
OMAiELIMIIP
OrthoDBi1059294at2759
PhylomeDBiQ8IVJ1
TreeFamiTF313647

Enzyme and pathway databases

PathwayCommonsiQ8IVJ1
ReactomeiR-HSA-425410, Metal ion SLC transporters

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
254428, 8 hits in 870 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
SLC41A1, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
254428
PharosiQ8IVJ1, Tbio

Protein Ontology

More...
PROi
PR:Q8IVJ1
RNActiQ8IVJ1, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000133065, Expressed in left ventricle myocardium and 204 other tissues
ExpressionAtlasiQ8IVJ1, baseline and differential
GenevisibleiQ8IVJ1, HS

Family and domain databases

InterProiView protein in InterPro
IPR006667, SLC41_membr_dom
IPR036739, SLC41_membr_dom_sf
PfamiView protein in Pfam
PF01769, MgtE, 2 hits
SUPFAMiSSF161093, SSF161093, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiS41A1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8IVJ1
Secondary accession number(s): Q63HJ4
, Q658Z5, Q659A4, Q6MZK2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: July 10, 2007
Last modified: October 7, 2020
This is version 129 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
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Main funding by: National Institutes of Health

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