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Entry version 121 (05 Jun 2019)
Sequence version 2 (26 Feb 2008)
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Protein

Protein AHNAK2

Gene

AHNAK2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

  • regulation of RNA splicing Source: GO_Central

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein AHNAK2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:AHNAK2
Synonyms:C14orf78, KIAA2019
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 14

Organism-specific databases

Human Gene Nomenclature Database

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HGNCi
HGNC:20125 AHNAK2

Online Mendelian Inheritance in Man (OMIM)

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MIMi
608570 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8IVF2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
113146

Open Targets

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OpenTargetsi
ENSG00000185567

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162376085

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

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BioMutai
AHNAK2

Domain mapping of disease mutations (DMDM)

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DMDMi
172045740

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003199621 – 5795Protein AHNAK2Add BLAST5795

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki116Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei280PhosphoserineCombined sources1
Modified residuei294PhosphoserineCombined sources1
Modified residuei593PhosphoserineCombined sources1
Modified residuei842PhosphoserineCombined sources1
Modified residuei1007PhosphoserineCombined sources1
Modified residuei1112PhosphoserineCombined sources1
Modified residuei1337PhosphoserineCombined sources1
Modified residuei1418PhosphoserineCombined sources1
Modified residuei1502PhosphoserineCombined sources1
Modified residuei1510N6-acetyllysineCombined sources1
Modified residuei1667PhosphoserineCombined sources1
Modified residuei1832PhosphoserineCombined sources1
Modified residuei1840N6-acetyllysineCombined sources1
Modified residuei2162PhosphoserineCombined sources1
Modified residuei2243PhosphoserineCombined sources1
Modified residuei2408PhosphoserineCombined sources1
Modified residuei2492PhosphoserineCombined sources1
Modified residuei2500N6-acetyllysineCombined sources1
Modified residuei2738PhosphoserineCombined sources1
Modified residuei2822PhosphoserineCombined sources1
Modified residuei2987PhosphoserineCombined sources1
Modified residuei3068PhosphoserineCombined sources1
Modified residuei3152PhosphoserineCombined sources1
Modified residuei3233PhosphoserineCombined sources1
Modified residuei3408PhosphoserineCombined sources1
Modified residuei3812PhosphoserineCombined sources1
Modified residuei3977PhosphoserineCombined sources1
Modified residuei4142PhosphoserineCombined sources1
Modified residuei4307PhosphoserineCombined sources1
Modified residuei4388PhosphoserineCombined sources1
Modified residuei4472PhosphoserineCombined sources1
Modified residuei4477PhosphoserineCombined sources1
Modified residuei4894PhosphoserineCombined sources1
Modified residuei4897PhosphoserineCombined sources1
Modified residuei5707PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
Q8IVF2

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
Q8IVF2

MaxQB - The MaxQuant DataBase

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MaxQBi
Q8IVF2

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8IVF2

PeptideAtlas

More...
PeptideAtlasi
Q8IVF2

PRoteomics IDEntifications database

More...
PRIDEi
Q8IVF2

ProteomicsDB human proteome resource

More...
ProteomicsDBi
70688
70689 [Q8IVF2-2]
70690 [Q8IVF2-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

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iPTMneti
Q8IVF2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8IVF2

SwissPalm database of S-palmitoylation events

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SwissPalmi
Q8IVF2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSG00000185567 Expressed in 193 organ(s), highest expression level in tendon of biceps brachii

Genevisible search portal to normalized and curated expression data from Genevestigator

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Genevisiblei
Q8IVF2 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA000878
HPA002940
HPA004145
HPA020111

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer (via PDZ domain) (PubMed:24675079). Interacts with DYSF; the interaction is direct and Ca2+-independent (PubMed:17185750).2 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
125226, 29 interactors

Protein interaction database and analysis system

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IntActi
Q8IVF2, 23 interactors

STRING: functional protein association networks

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STRINGi
9606.ENSP00000353114

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

15795
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q8IVF2

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini112 – 193PDZPROSITE-ProRule annotationAdd BLAST82

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
ENOG410IGCZ Eukaryota
ENOG41116CJ LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000163336

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
Q8IVF2

Identification of Orthologs from Complete Genome Data

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OMAi
GVGIKAH

Database of Orthologous Groups

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OrthoDBi
71329at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8IVF2

TreeFam database of animal gene trees

More...
TreeFami
TF350595

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR001478 PDZ
IPR036034 PDZ_sf

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00228 PDZ, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50156 SSF50156, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50106 PDZ, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q8IVF2-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MCDCFHMVLP TWPGTPGSVS GRQLQPGEPG AETEDDHSVT EGPADEGIRP
60 70 80 90 100
RPQGSSPVYE YTTEAADFGL QEDAPGRQGS AGRRRSWWKR DSGDSRTFFR
110 120 130 140 150
MSRPEAVQEA TEVTLKTEVE AGASGYSVTG GGDQGIFVKQ VLKDSSAAKL
160 170 180 190 200
FNLREGDQLL STTVFFENIK YEDALKILQY SEPYKVQFKI RRQLPAPQDE
210 220 230 240 250
EWASSDAQHG PQGKEKEDTD VADGCRETPT KTLEGDGDQE RLISKPRVGR
260 270 280 290 300
GRQSQRERLS WPKFQSIKSK RGPGPQRSHS SSEAYEPRDA HDVSPTSTDT
310 320 330 340 350
EAQLTVERQE QKAGPGSQRR RKFLNLRFRT GSGQGPSSTG QPGRGFQSGV
360 370 380 390 400
GRAGVLEELG PWGDSLEETG AATGSRREER AEQDREVMPA QSMPLPTELG
410 420 430 440 450
DPRLCEGTPQ EGGLRAARLH GKTLEGQAQE TAVAQRKPRA QPTPGMSREG
460 470 480 490 500
EGEGLQSLEI GIARLSLRDT TEGGTQIGPP EIRVRVHDLK TPKFAFSTEK
510 520 530 540 550
EPERERRLST PQRGKRQDAS SKAGTGLKGE EVEGAGWMPG REPTTHAEAQ
560 570 580 590 600
GDEGDGEEGL QRTRITEEQD KGREDTEGQI RMPKFKIPSL GWSPSKHTKT
610 620 630 640 650
GREKATEDTE QGREGEATAT ADRREQRRTE EGLKDKEDSD SMTNTTKIQL
660 670 680 690 700
IHDEKRLKKE QILTEKEVAT KDSKFKMPKF KMPLFGASAP GKSMEASVDV
710 720 730 740 750
SAPKVEADVS LLSMQGDLKT TDLSVQTPSA DLEVQDGQVD VKLPEGPLPE
760 770 780 790 800
GASLKGHLPK VQRPSLKMPK VDLKGPKLDL KGPKAEVTAP DVKMSLSSME
810 820 830 840 850
VDVQAPRAKL DGARLEGDLS LADKEVTAKD SKFKMPKFKM PSFGVSAPGK
860 870 880 890 900
SMEDSVDVSA PKVEADVSLS SMQGDLKATD LSIQPPSADL EVQAGQVDVK
910 920 930 940 950
LPEGPVPEGA GPKVHLPKVE MPSFKMPKVD LKGPQIDVKG PKLDLKGPKA
960 970 980 990 1000
EVTAPDGEVS LPSMEVDVQA QKAKLDGAWL EGDLSLADKD VTAKDSKFKM
1010 1020 1030 1040 1050
PKFKMPSFGV SAPGKSIKAL VDVSAPKVEA DLSLPSMQGD LKTTDLSIQP
1060 1070 1080 1090 1100
ASTDLKVQAD QVDVKLPEGH LPEGAGLKGH LPKVEMPSFK MPKVALKGPQ
1110 1120 1130 1140 1150
VDVKGPKLDL KSPKAEVTAP DVEVSLPSVE VDVEAPGAKL DSARLEGELS
1160 1170 1180 1190 1200
LADKDVTAKD SRFKMPKFKM PSFGASAPGK SIEASVDVSA PKVEADVSLP
1210 1220 1230 1240 1250
SMQGDLKTTD LSIQPPSADL EVHAGQVDVK LLEGHVPEGA GFKGHLPKVQ
1260 1270 1280 1290 1300
MPSLKMPKVD LKGPQVEVRG PKLDLKGHKA EVTAHEVAVS LPSVEVDMQA
1310 1320 1330 1340 1350
PGAKLDGAQL DGDLSLADKD VTAKDSKFKM PKFKMPSFGV SAPGKSIEAS
1360 1370 1380 1390 1400
VDLSAPKVEA DMSLPSMQGD LKTTDLSIQP PSTDLELQAG QLDVKLPEGP
1410 1420 1430 1440 1450
VPEGAGLKGH LPKLQMPSFK VPKVDLKGPE IDIKGPKLDL KDPKVEVTAP
1460 1470 1480 1490 1500
DVEVSLPSVE VDVEAPGAKL DGGRLEEDMS LADKDLTTKD SKFKMPKFKM
1510 1520 1530 1540 1550
PSFGVSAPGK SIEASVDVSA PKVEADVSLP SMQGDLKATD LSIQPPSADL
1560 1570 1580 1590 1600
EVQAGQVDVK LPEGPVSEGA GLKGHLPKVQ MPSFKMPKVD LKGPQIDVKG
1610 1620 1630 1640 1650
PKLDLKGPKV EVTAPDVKMS LSSMEVDVQA PRAKLDGAQL EGDLSLADKA
1660 1670 1680 1690 1700
VTAKDSKFKM PKFKMPSFGV SAPGKSIEAS VDVSEPKVEA DVSLPSMQGD
1710 1720 1730 1740 1750
LKTTDLSIQS PSADLEVQAG QVNVKLPEGP LPEGAGFKGH LPKVQMPSLK
1760 1770 1780 1790 1800
MPKVALKGPQ MDVKGPKLDL KGPKAEVMAP DVEVSLPSVE VDVEAPGAKL
1810 1820 1830 1840 1850
DSVRLEGDLS LADKDVTAKD SKFKMPKFKM PSFGVSAPGK SIEASVDVSA
1860 1870 1880 1890 1900
PKVEAEVSLP SMQGDLKTTD LCIPLPSADL VVQAGQVDMK LPEGQVPEGA
1910 1920 1930 1940 1950
GLKGHLPKVD MPSFKMPKVD LKGPQTDVKG AKLDLKGPKA EVTAPDVEVS
1960 1970 1980 1990 2000
LPSMEVDVQA QKAKLDGARL EGDLSLADKD MTAKDSKFKM PKFKMPSFGV
2010 2020 2030 2040 2050
SAPGRSIEAS VDVPAPKVEA DVSLPSMQGD LKTTDLSIQP PSADLKVQTG
2060 2070 2080 2090 2100
QVDVKLPEGH VPEGAGLKGH LPKVEMPSLK MPKVDLKGPQ VDIKGPKLDL
2110 2120 2130 2140 2150
KDPKVEMRVP DVEVSLPSME VDVQAPRAKL DSAHLQGDLT LANKDLTTKD
2160 2170 2180 2190 2200
SKFKMPKFKM PSFGVSAPGK SIEASVDVSP PKVEADMSLP SMQGDLKTTD
2210 2220 2230 2240 2250
LSIQPLSADV KVQAGQVDVK LLEGPVPEEV GLKGHLPKLQ MPSFKVPKVD
2260 2270 2280 2290 2300
LKGPEIDIKG PKLDLKDPKV EVTAPDVEVS LPSVEVDVKA PGAKLDGARL
2310 2320 2330 2340 2350
EGDMSLADKD VTAKDSKFKM PKFKMLSFGV SALGKSIEAS ADVSALKVEA
2360 2370 2380 2390 2400
DVSLPSMQGD LKTTDLSVQP PSADLEVQAG QVDVKLPEGP VPEGAGLKGH
2410 2420 2430 2440 2450
LPKLQMPSFK MPKVDLKGPQ IDVKGPKLDL KGPKTDVMAP DVEVSQPSVE
2460 2470 2480 2490 2500
VDVEAPGAKL DGAWLEGDLS VADKDVTTKD SRFKIPKFKM PSFGVSAPGK
2510 2520 2530 2540 2550
SIEASVDVSA PKVEADGSLS SMQGDLKATD LSIQPPSADL EVQAGQVDVK
2560 2570 2580 2590 2600
LPEGPVPEGA GLKGHLPKVQ MPSFKMPEMD LKGPQLDVKG PKLDLKGPKA
2610 2620 2630 2640 2650
EVTAPDVEMS LSSMEVDVQA PRAKLDGARL EGDLSLADKG VTAKDSKFKM
2660 2670 2680 2690 2700
PKFKMPSFRV SAPGESIEAL VDVSELKVEA DMSLPSMQGD LKTTDISIQP
2710 2720 2730 2740 2750
PSAQLEVQAG QVDVKLPEGH VPEGAGLKGH LPKLQMPSFK MPEVDLKGPQ
2760 2770 2780 2790 2800
IDVKGPNVDL KGPKAEVTAP DVKMSLSSME VDVQAPRAKL DGARLEGDLS
2810 2820 2830 2840 2850
LADKGMTAKD SKFKMPKFKM PSFGVSAPGK SIEASVDVSE LKVEADGSFP
2860 2870 2880 2890 2900
SMQGDLKTTD IRIQPPSAQL EVQAGQVDVK LPEGHVPEGA GLKGHLPKVQ
2910 2920 2930 2940 2950
MPSFKMPKVD LKGPQIDVKG PKLDLKGPKA EVTAPDVEVS LPSVEVDVEA
2960 2970 2980 2990 3000
PRAKLDGARL EGDLSLADKD VTAKDSKFKM PKFKMPSFGV SAPGKSIEVS
3010 3020 3030 3040 3050
VDVSAPKVEA EVSLPSMQGD LKTTDISIEP PSAQLEVQAG QVDLKLPEGH
3060 3070 3080 3090 3100
VPEGAGLKGH LPKLQMPSFK MPKVDRKGPQ IDVKGPKLDL KGPKTDVTAP
3110 3120 3130 3140 3150
DVEVSQPGME VDVEAPGAKL DGARLEGDLS LADKDVTAKD SKFKMPKFKM
3160 3170 3180 3190 3200
PSFGVSAPGK SIEVLVDVSA PKVEADLSLP SMQGDLKNTD ISIEPPSAQL
3210 3220 3230 3240 3250
EVQAGQVDVK LPEGHVLEGA GLKGHLPKLQ MPSFKMPKVD RKGPQIDIKG
3260 3270 3280 3290 3300
PKLDLKGPKM DVTAPDVEVS QPSMEVDVEA PGAKLDGARL EGDLSLADKD
3310 3320 3330 3340 3350
VTAKDSKFKM PKFKMPSYRA SAPGKSIQAS VDVSAPKAEA DVSLPSMQGD
3360 3370 3380 3390 3400
LKTTDLSIQL PSVDLEVQAG QVDVKLPEGH VPEGAGLKGH LPKVEMPSFK
3410 3420 3430 3440 3450
MPKVDLKSPQ VDIKGPKLDL KVPKAEVTVP DVEVSLPSVE VDVQAPRAKL
3460 3470 3480 3490 3500
DGARLEGDLS LAEKDVTAKD SKFKMPKFKM PSFGVSAPGR SIEASLDVSA
3510 3520 3530 3540 3550
PKVEADVSLS SMQGDLKATD LSIQPPSADL EVQAVQVDVE LLEGPVPEGA
3560 3570 3580 3590 3600
GLKGHLPKVE MPSLKTPKVD LKGPQIDVKG PKLDLKGPKA EVRVPDVEVS
3610 3620 3630 3640 3650
LPSVEVDVQA PKAKLDAGRL EGDLSLADKD VTAKDSKFKM PKFKMPSFRV
3660 3670 3680 3690 3700
SAPGKSMEAS VDVSAPKVEA DVSLPSMQGD LKTTDLSIQP PSADLKVQAG
3710 3720 3730 3740 3750
QMDVKLPEGQ VPEGAGLKEH LPKVEMPSLK MPKVDLKGPQ VDIKGPKLDL
3760 3770 3780 3790 3800
KVSKAEVTAP DVEVSLPSVE VDVQAPRAKL DSAQLEGDLS LADKDVTAKD
3810 3820 3830 3840 3850
SKFKMPKFKM PSFGVSAPGK SIEASVHVSA PKVEADVSLP SMQGDLKTTD
3860 3870 3880 3890 3900
LSIQPHSADL TVQARQVDMK LLEGHVPEEA GLKGHLPKVQ MPSFKMPKVD
3910 3920 3930 3940 3950
LKGPEIDIKG PKLDLKDPKV EVTAPDVEVS LPSVEVDVEA PGAKLDGARL
3960 3970 3980 3990 4000
EGDLSLADKD MTAKDSKFKM PKFKMPSFGV SAPGKSMEAS VDVTAPKVEA
4010 4020 4030 4040 4050
DVSLPSMQGD LKATDLSVQP PSADLEVQAG QVDVKLPEGP VPEGASLKGH
4060 4070 4080 4090 4100
LPKVQMPSFK MPKVDLKGPQ IDVKGPKLDL KGPKAEVTAP DVKMSLSSME
4110 4120 4130 4140 4150
VDVQAPRAKL DGVQLEGDLS LADKDVTAKD SKFKMPKFKM PSFGVSAPGK
4160 4170 4180 4190 4200
SMEASVDVSE LKAKADVSLP SMQGDLKTTD LSIQSPSADL EVQAGQVDVK
4210 4220 4230 4240 4250
LPEGPLPKGA GLKGHLPKVQ MPCLKMPKVA LKGPQVDVKG PKLDLKGPKA
4260 4270 4280 4290 4300
DVMTPVVEVS LPSMEVDVEA PGAKLDSVRL EGDLSLADKD MTAKDSKFKM
4310 4320 4330 4340 4350
PKFKMPSFGV SAPGKSIEAS LDVSALKVEA DVSLPSMQGD LKTTHLSIQP
4360 4370 4380 4390 4400
PSADLEVQAG QEDVKLPEGP VHEGAGLKGH LPKLQMPSFK VPKVDLKGPQ
4410 4420 4430 4440 4450
IDVNVPKLDL KGPKVEVTSP NLDVSLPSME VDIQAPGAKL DSTRLEGDLS
4460 4470 4480 4490 4500
LADKDVTAKD SKFKMPKFKM PSFGMLSPGK SIEVSVDVSA PKMEADMSIP
4510 4520 4530 4540 4550
SMQGDLKTTD LRIQAPSADL EVQAGQVDLK LPEGHMPEVA GLKGHLPKVE
4560 4570 4580 4590 4600
MPSFKMPKVD LKGPQVDVKG PKLDLKGPKA EVMAPDVEVS LPSVETDVQA
4610 4620 4630 4640 4650
PGSMLDGARL EGDLSLAHED VAGKDSKFQG PKLSTSGFEW SSKKVSMSSS
4660 4670 4680 4690 4700
EIEGNVTFHE KTSTFPIVES VVHEGDLHDP SRDGNLGLAV GEVGMDSKFK
4710 4720 4730 4740 4750
KLHFKVPKVS FSSTKTPKDS LVPGAKSSIG LSTIPLSSSE CSSFELQQVS
4760 4770 4780 4790 4800
ACSEPSMQMP KVGFAGFPSS RLDLTGPHFE SSILSPCEDV TLTKYQVTVP
4810 4820 4830 4840 4850
RAALAPELAL EIPSGSQADI PLPKTECSTD LQPPEGVPTS QAESHSGPLN
4860 4870 4880 4890 4900
SMIPVSLGQV SFPKFYKPKF VFSVPQMAVP EGDLHAAVGA PVMSPLSPGE
4910 4920 4930 4940 4950
RVQCPLPSTQ LPSPGTCVSQ GPEELVASLQ TSVVAPGEAP SEDADHEGKG
4960 4970 4980 4990 5000
SPLKMPKIKL PSFRWSPKKE TGPKVDPECS VEDSKLSLVL DKDEVAPQSA
5010 5020 5030 5040 5050
IHMDLPPERD GEKGRSTKPG FAMPKLALPK MKASKSGVSL PQRDVDPSLS
5060 5070 5080 5090 5100
SATAGGSFQD TEKASSDGGR GGLGATASAT GSEGVNLHRP QVHIPSLGFA
5110 5120 5130 5140 5150
KPDLRSSKAK VEVSQPEADL PLPKHDLSTE GDSRGCGLGD VPVSQPCGEG
5160 5170 5180 5190 5200
IAPTPEDPLQ PSCRKPDAEV LTVESPEEEA MTKYSQESWF KMPKFRMPSL
5210 5220 5230 5240 5250
RRSFRDRGGA GKLEVAQTQA PAATGGEAAA KVKEFLVSGS NVEAAMSLQL
5260 5270 5280 5290 5300
PEADAEVTAS ESKSSTDILR CDLDSTGLKL HLSTAGMTGD ELSTSEVRIH
5310 5320 5330 5340 5350
PSKGPLPFQM PGMRLPETQV LPGEIDETPL SKPGHDLASM EDKTEKWSSQ
5360 5370 5380 5390 5400
PEGPLKLKAS STDMPSQISV VNVDQLWEDS VLTVKFPKLM VPRFSFPAPS
5410 5420 5430 5440 5450
SEDDVFIPTV REVQCPEANI DTALCKESPG LWGASILKAG AGVPGEQPVD
5460 5470 5480 5490 5500
LNLPLEAPPI SKVRVHIQGA QVESQEVTIH SIVTPEFVDL SVPRTFSTQI
5510 5520 5530 5540 5550
VRESEIPTSE IQTPSYGFSL LKVKIPEPHT QARVYTTMTQ HSRTQEGTEE
5560 5570 5580 5590 5600
APIQATPGVD SISGDLQPDT GEPFEMISSS VNVLGQQTLT FEVPSGHQLA
5610 5620 5630 5640 5650
DSCSDEEPAE ILEFPPDDSQ EATTPLADEG RAPKDKPESK KSGLLWFWLP
5660 5670 5680 5690 5700
NIGFSSSVDE TGVDSKNDVQ RSAPIQTQPE ARPEAELPKK QEKAGWFRFP
5710 5720 5730 5740 5750
KLGFSSSPTK KSKSTEDGAE LEEQKLQEET ITFFDARESF SPEEKEEGEL
5760 5770 5780 5790
IGPVGTGLDS RVMVTSAART ELILPEQDRK ADDESKGSGL GPNEG
Length:5,795
Mass (Da):616,629
Last modified:February 26, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBEC73677308C1FAB
GO
Isoform 2 (identifier: Q8IVF2-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-5002: Missing.

Note: No experimental confirmation available.
Show »
Length:793
Mass (Da):85,128
Checksum:iE2543EB1BE640F9A
GO
Isoform 3 (identifier: Q8IVF2-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-100: Missing.

Show »
Length:5,695
Mass (Da):605,648
Checksum:i3EC13F00BECDE25A
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH49216 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAH90889 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAC23115 differs from that shown. Reason: Frameshift at position 3008.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti3195P → L in BAC23115 (Ref. 4) Curated1
Sequence conflicti3198A → V in BAC23115 (Ref. 4) Curated1
Sequence conflicti4740E → G in CAD98019 (PubMed:17974005).Curated1
Sequence conflicti5269L → P in CAD98019 (PubMed:17974005).Curated1
Sequence conflicti5560D → G in CAD97904 (PubMed:17974005).Curated1
Sequence conflicti5577I → V in CAD97904 (PubMed:17974005).Curated1
Sequence conflicti5590T → A in CAD97981 (PubMed:17974005).Curated1
Sequence conflicti5601D → G in CAD98034 (PubMed:17974005).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_050635525T → A. Corresponds to variant dbSNP:rs2278607Ensembl.1
Natural variantiVAR_0390691266V → M. Corresponds to variant dbSNP:rs748458962Ensembl.1
Natural variantiVAR_0615481298M → I. Corresponds to variant dbSNP:rs2819440Ensembl.1
Natural variantiVAR_0390701470L → V. 1
Natural variantiVAR_0595601856E → D. Corresponds to variant dbSNP:rs2819435Ensembl.1
Natural variantiVAR_0506362107M → V. Corresponds to variant dbSNP:rs11846918Ensembl.1
Natural variantiVAR_0390712115S → R. Corresponds to variant dbSNP:rs2582514Ensembl.1
Natural variantiVAR_0595612146L → V. Corresponds to variant dbSNP:rs12890949Ensembl.1
Natural variantiVAR_0506372410K → R. Corresponds to variant dbSNP:rs11845746Ensembl.1
Natural variantiVAR_0390722429D → E. Corresponds to variant dbSNP:rs11160826Ensembl.1
Natural variantiVAR_0390732430L → V. Corresponds to variant dbSNP:rs2819426Ensembl.1
Natural variantiVAR_0595622503E → A. Corresponds to variant dbSNP:rs2819429Ensembl.1
Natural variantiVAR_0390742616V → A. Corresponds to variant dbSNP:rs4264326Ensembl.1
Natural variantiVAR_0595632862R → S. Corresponds to variant dbSNP:rs2582514Ensembl.1
Natural variantiVAR_0595643176D → E. Corresponds to variant dbSNP:rs11160826Ensembl.1
Natural variantiVAR_0595653177L → V. Corresponds to variant dbSNP:rs2819426Ensembl.1
Natural variantiVAR_0595663336P → L. Corresponds to variant dbSNP:rs10438247Ensembl.1
Natural variantiVAR_0595673363V → A. Corresponds to variant dbSNP:rs4264326Ensembl.1
Natural variantiVAR_0615493654G → E. Corresponds to variant dbSNP:rs28380382Ensembl.1
Natural variantiVAR_0595683793D → N. Corresponds to variant dbSNP:rs11160825Ensembl.1
Natural variantiVAR_0506383796V → L. 1
Natural variantiVAR_0595693869M → V. Corresponds to variant dbSNP:rs10438246Ensembl.1
Natural variantiVAR_0595703902K → N. Corresponds to variant dbSNP:rs2819423Ensembl.1
Natural variantiVAR_0506393961M → V. Corresponds to variant dbSNP:rs10141053Ensembl.1
Natural variantiVAR_0506404071I → M. Corresponds to variant dbSNP:rs2582511Ensembl.1
Natural variantiVAR_0595714085A → V. Corresponds to variant dbSNP:rs2013462Ensembl.1
Natural variantiVAR_0506414138F → L. Corresponds to variant dbSNP:rs2582505Ensembl.1
Natural variantiVAR_0595724198D → N. Corresponds to variant dbSNP:rs534942818Ensembl.1
Natural variantiVAR_0506424232K → N. Corresponds to variant dbSNP:rs2819423Ensembl.1
Natural variantiVAR_0506434278V → A. Corresponds to variant dbSNP:rs2819422Ensembl.1
Natural variantiVAR_0595734326L → P. Corresponds to variant dbSNP:rs2819421Ensembl.1
Natural variantiVAR_0595744478P → L. Corresponds to variant dbSNP:rs2582513Ensembl.1
Natural variantiVAR_0506444536M → L. Corresponds to variant dbSNP:rs9672139Ensembl.1
Natural variantiVAR_0506454664T → A1 PublicationCorresponds to variant dbSNP:rs4465542Ensembl.1
Natural variantiVAR_0390755028L → M. Corresponds to variant dbSNP:rs9672139Ensembl.1
Natural variantiVAR_0506465072G → R. Corresponds to variant dbSNP:rs2819420Ensembl.1
Natural variantiVAR_0615505139G → E. Corresponds to variant dbSNP:rs61421370Ensembl.1
Natural variantiVAR_0506475184Y → D1 PublicationCorresponds to variant dbSNP:rs2819419Ensembl.1
Natural variantiVAR_0506485397P → A2 PublicationsCorresponds to variant dbSNP:rs3742935Ensembl.1
Natural variantiVAR_0390765564G → R. Corresponds to variant dbSNP:rs2819420Ensembl.1
Natural variantiVAR_0506495732T → M. Corresponds to variant dbSNP:rs748358Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0315501 – 5002Missing in isoform 2. 1 PublicationAdd BLAST5002
Alternative sequenceiVSP_0315511 – 100Missing in isoform 3. 2 PublicationsAdd BLAST100

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL512802 Genomic DNA No translation available.
AI915159 mRNA No translation available.
BC011859 mRNA Translation: AAH11859.2
BC033372 mRNA Translation: AAH33372.1
BC049216 mRNA Translation: AAH49216.1 Different initiation.
BC090889 mRNA Translation: AAH90889.1 Different initiation.
AK094143 mRNA No translation available.
AB095939 mRNA Translation: BAC23115.1 Frameshift.
AL834367 mRNA Translation: CAD39030.1
BX537923 mRNA Translation: CAD97904.1
BX538040 mRNA Translation: CAD97981.1
BX538106 mRNA Translation: CAD98019.1
BX538133 mRNA Translation: CAD98034.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS45177.1 [Q8IVF2-1]

NCBI Reference Sequences

More...
RefSeqi
NP_612429.2, NM_138420.2 [Q8IVF2-1]
XP_005267356.1, XM_005267299.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000333244; ENSP00000353114; ENSG00000185567 [Q8IVF2-1]
ENST00000557457; ENSP00000450998; ENSG00000185567 [Q8IVF2-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
113146

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:113146

UCSC genome browser

More...
UCSCi
uc010axc.2 human [Q8IVF2-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL512802 Genomic DNA No translation available.
AI915159 mRNA No translation available.
BC011859 mRNA Translation: AAH11859.2
BC033372 mRNA Translation: AAH33372.1
BC049216 mRNA Translation: AAH49216.1 Different initiation.
BC090889 mRNA Translation: AAH90889.1 Different initiation.
AK094143 mRNA No translation available.
AB095939 mRNA Translation: BAC23115.1 Frameshift.
AL834367 mRNA Translation: CAD39030.1
BX537923 mRNA Translation: CAD97904.1
BX538040 mRNA Translation: CAD97981.1
BX538106 mRNA Translation: CAD98019.1
BX538133 mRNA Translation: CAD98034.1
CCDSiCCDS45177.1 [Q8IVF2-1]
RefSeqiNP_612429.2, NM_138420.2 [Q8IVF2-1]
XP_005267356.1, XM_005267299.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4CN0X-ray1.75A/B108-203[»]
SMRiQ8IVF2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi125226, 29 interactors
IntActiQ8IVF2, 23 interactors
STRINGi9606.ENSP00000353114

PTM databases

iPTMnetiQ8IVF2
PhosphoSitePlusiQ8IVF2
SwissPalmiQ8IVF2

Polymorphism and mutation databases

BioMutaiAHNAK2
DMDMi172045740

Proteomic databases

EPDiQ8IVF2
jPOSTiQ8IVF2
MaxQBiQ8IVF2
PaxDbiQ8IVF2
PeptideAtlasiQ8IVF2
PRIDEiQ8IVF2
ProteomicsDBi70688
70689 [Q8IVF2-2]
70690 [Q8IVF2-3]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
113146
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000333244; ENSP00000353114; ENSG00000185567 [Q8IVF2-1]
ENST00000557457; ENSP00000450998; ENSG00000185567 [Q8IVF2-2]
GeneIDi113146
KEGGihsa:113146
UCSCiuc010axc.2 human [Q8IVF2-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
113146
DisGeNETi113146

GeneCards: human genes, protein and diseases

More...
GeneCardsi
AHNAK2

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0012023
HGNCiHGNC:20125 AHNAK2
HPAiHPA000878
HPA002940
HPA004145
HPA020111
MIMi608570 gene
neXtProtiNX_Q8IVF2
OpenTargetsiENSG00000185567
PharmGKBiPA162376085

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IGCZ Eukaryota
ENOG41116CJ LUCA
GeneTreeiENSGT00940000163336
InParanoidiQ8IVF2
OMAiGVGIKAH
OrthoDBi71329at2759
PhylomeDBiQ8IVF2
TreeFamiTF350595

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
AHNAK2 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
113146

Protein Ontology

More...
PROi
PR:Q8IVF2

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000185567 Expressed in 193 organ(s), highest expression level in tendon of biceps brachii
GenevisibleiQ8IVF2 HS

Family and domain databases

InterProiView protein in InterPro
IPR001478 PDZ
IPR036034 PDZ_sf
SMARTiView protein in SMART
SM00228 PDZ, 1 hit
SUPFAMiSSF50156 SSF50156, 1 hit
PROSITEiView protein in PROSITE
PS50106 PDZ, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiAHNK2_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8IVF2
Secondary accession number(s): Q5BKX7
, Q7Z343, Q7Z358, Q7Z394, Q7Z3G0, Q86WQ6, Q8IYY1, Q8N3G4, Q96EX9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: February 26, 2008
Last modified: June 5, 2019
This is version 121 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Human chromosome 14
    Human chromosome 14: entries, gene names and cross-references to MIM
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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