UniProtKB - Q8IVB5 (LIX1L_HUMAN)
Protein
LIX1-like protein
Gene
LIX1L
Organism
Homo sapiens (Human)
Status
Functioni
GO - Biological processi
- autophagosome maturation Source: GO_Central
- autophagy Source: GO_Central
Enzyme and pathway databases
PathwayCommonsi | Q8IVB5 |
Names & Taxonomyi
Protein namesi | Recommended name: LIX1-like protein |
Gene namesi | Name:LIX1L |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000271601.3 |
HGNCi | HGNC:28715, LIX1L |
neXtProti | NX_Q8IVB5 |
Subcellular locationi
Other locations
- cytoplasm Source: GO_Central
Pathology & Biotechi
Organism-specific databases
DisGeNETi | 128077 |
OpenTargetsi | ENSG00000271601 |
PharmGKBi | PA134915428 |
Miscellaneous databases
Pharosi | Q8IVB5, Tdark |
Polymorphism and mutation databases
BioMutai | LIX1L |
DMDMi | 74728055 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000232872 | 1 – 337 | LIX1-like proteinAdd BLAST | 337 |
Proteomic databases
EPDi | Q8IVB5 |
jPOSTi | Q8IVB5 |
MassIVEi | Q8IVB5 |
MaxQBi | Q8IVB5 |
PaxDbi | Q8IVB5 |
PeptideAtlasi | Q8IVB5 |
PRIDEi | Q8IVB5 |
ProteomicsDBi | 70679 |
TopDownProteomicsi | Q8IVB5 |
PTM databases
iPTMneti | Q8IVB5 |
PhosphoSitePlusi | Q8IVB5 |
Expressioni
Gene expression databases
Bgeei | ENSG00000271601, Expressed in gastrocnemius and 223 other tissues |
Genevisiblei | Q8IVB5, HS |
Organism-specific databases
HPAi | ENSG00000271601, Low tissue specificity |
Interactioni
Protein-protein interaction databases
BioGRIDi | 126092, 9 interactors |
IntActi | Q8IVB5, 4 interactors |
STRINGi | 9606.ENSP00000474487 |
Miscellaneous databases
RNActi | Q8IVB5, protein |
Family & Domainsi
Sequence similaritiesi
Belongs to the LIX1 family.Curated
Phylogenomic databases
eggNOGi | ENOG502QR91, Eukaryota |
GeneTreei | ENSGT00390000005869 |
HOGENOMi | CLU_065651_0_1_1 |
InParanoidi | Q8IVB5 |
OMAi | HPSRKIT |
OrthoDBi | 1026341at2759 |
PhylomeDBi | Q8IVB5 |
TreeFami | TF324035 |
Family and domain databases
InterProi | View protein in InterPro IPR029270, LIX1 |
Pfami | View protein in Pfam PF14954, LIX1, 1 hit |
i Sequence
Sequence statusi: Complete.
Q8IVB5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
METMRAQRLQ PGVGTSGRGT LRALRPGVTG AAAATATPPA GPPPAPPPPA
60 70 80 90 100
PPPPPLLLSG APGLPLPPGA AGSPAVLREA VEAVVRSFAK HTQGYGRVNV
110 120 130 140 150
VEALQEFWQM KQSRGADLKN GALVVYEMVP SNSPPYVCYV TLPGGSCFGS
160 170 180 190 200
FQFCPTKAEA RRSAAKIALM NSVFNEHPSR RITDEFIEKS VSEALASFNG
210 220 230 240 250
NREEADNPNT GIGAFRFMLE SNKGKSMLEF QELMTVFQLL HWNGSLKAMR
260 270 280 290 300
ERQCSRQEVL AHYSHRALDD DIRHQMALDW VSREQSVPGA LSRELASTER
310 320 330
ELDEARLAGK ELRFHKEKKD ILVLAAGQLG NMHSSNC
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC035727 mRNA Translation: AAH35727.1 CR627381 mRNA Translation: CAH10478.1 |
CCDSi | CCDS72873.1 |
RefSeqi | NP_714924.1, NM_153713.2 |
Genome annotation databases
Ensembli | ENST00000604000; ENSP00000474487; ENSG00000271601 |
GeneIDi | 128077 |
KEGGi | hsa:128077 |
UCSCi | uc001enr.5, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC035727 mRNA Translation: AAH35727.1 CR627381 mRNA Translation: CAH10478.1 |
CCDSi | CCDS72873.1 |
RefSeqi | NP_714924.1, NM_153713.2 |
3D structure databases
SMRi | Q8IVB5 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 126092, 9 interactors |
IntActi | Q8IVB5, 4 interactors |
STRINGi | 9606.ENSP00000474487 |
PTM databases
iPTMneti | Q8IVB5 |
PhosphoSitePlusi | Q8IVB5 |
Polymorphism and mutation databases
BioMutai | LIX1L |
DMDMi | 74728055 |
Proteomic databases
EPDi | Q8IVB5 |
jPOSTi | Q8IVB5 |
MassIVEi | Q8IVB5 |
MaxQBi | Q8IVB5 |
PaxDbi | Q8IVB5 |
PeptideAtlasi | Q8IVB5 |
PRIDEi | Q8IVB5 |
ProteomicsDBi | 70679 |
TopDownProteomicsi | Q8IVB5 |
Protocols and materials databases
Antibodypediai | 73360, 102 antibodies |
Genome annotation databases
Ensembli | ENST00000604000; ENSP00000474487; ENSG00000271601 |
GeneIDi | 128077 |
KEGGi | hsa:128077 |
UCSCi | uc001enr.5, human |
Organism-specific databases
CTDi | 128077 |
DisGeNETi | 128077 |
EuPathDBi | HostDB:ENSG00000271601.3 |
GeneCardsi | LIX1L |
HGNCi | HGNC:28715, LIX1L |
HPAi | ENSG00000271601, Low tissue specificity |
neXtProti | NX_Q8IVB5 |
OpenTargetsi | ENSG00000271601 |
PharmGKBi | PA134915428 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG502QR91, Eukaryota |
GeneTreei | ENSGT00390000005869 |
HOGENOMi | CLU_065651_0_1_1 |
InParanoidi | Q8IVB5 |
OMAi | HPSRKIT |
OrthoDBi | 1026341at2759 |
PhylomeDBi | Q8IVB5 |
TreeFami | TF324035 |
Enzyme and pathway databases
PathwayCommonsi | Q8IVB5 |
Miscellaneous databases
BioGRID-ORCSi | 128077, 6 hits in 842 CRISPR screens |
ChiTaRSi | LIX1L, human |
GenomeRNAii | 128077 |
Pharosi | Q8IVB5, Tdark |
PROi | PR:Q8IVB5 |
RNActi | Q8IVB5, protein |
Gene expression databases
Bgeei | ENSG00000271601, Expressed in gastrocnemius and 223 other tissues |
Genevisiblei | Q8IVB5, HS |
Family and domain databases
InterProi | View protein in InterPro IPR029270, LIX1 |
Pfami | View protein in Pfam PF14954, LIX1, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | LIX1L_HUMAN | |
Accessioni | Q8IVB5Primary (citable) accession number: Q8IVB5 Secondary accession number(s): Q6AI36 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 18, 2006 |
Last sequence update: | March 1, 2003 | |
Last modified: | December 2, 2020 | |
This is version 117 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families - Human chromosome 1
Human chromosome 1: entries, gene names and cross-references to MIM