LIX1L

Functionⁱ

GO - Biological processⁱ

autophagosome maturation Source: GO_Central

View the complete GO annotation on QuickGO ...

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: LIX1-like protein
Gene namesⁱ	Name:LIX1L
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 1

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000271601.3
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:28715 LIX1L
neXtProtⁱ	NX_Q8IVB5

Subcellular locationⁱ

GO - Cellular component

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000271601
PharmGKBⁱ	PA134915428

Polymorphism and mutation databases

DMDMⁱ	74728055

DMDMⁱ

74728055

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000232872	1 – 337	LIX1-like proteinAdd BLAST		337

Proteomic databases

EPDⁱ	Q8IVB5
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q8IVB5
PaxDbⁱ	Q8IVB5
PeptideAtlas More...PeptideAtlasⁱ	Q8IVB5
PRIDEⁱ	Q8IVB5
ProteomicsDBⁱ	70679
TopDownProteomicsⁱ	Q8IVB5

PTM databases

iPTMnetⁱ	Q8IVB5
PhosphoSitePlusⁱ	Q8IVB5

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000271601
CleanExⁱ	HS_LIX1L
Genevisibleⁱ	Q8IVB5 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA063598

HPAⁱ

HPA063598

Interactionⁱ

Protein-protein interaction databases

BioGridⁱ	126092, 9 interactors
IntActⁱ	Q8IVB5, 1 interactor
STRINGⁱ	9606.ENSP00000358314

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q8IVB5
SMRⁱ	Q8IVB5
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the LIX1 family.Curated

Phylogenomic databases

eggNOGⁱ	ENOG410IH13 Eukaryota ENOG410XRZR LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000005869
HOGENOMⁱ	HOG000237359
HOVERGENⁱ	HBG079509
InParanoidⁱ	Q8IVB5
KEGG Orthology (KO) More...KOⁱ	K16673
OMAⁱ	DWVNREQ
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0KAJ
PhylomeDBⁱ	Q8IVB5
TreeFamⁱ	TF324035

Family and domain databases

InterProⁱ	View protein in InterPro IPR029270 LIX1
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF14954 LIX1, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Q8IVB5-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
METMRAQRLQ PGVGTSGRGT LRALRPGVTG AAAATATPPA GPPPAPPPPA 
        60         70         80         90        100
PPPPPLLLSG APGLPLPPGA AGSPAVLREA VEAVVRSFAK HTQGYGRVNV 
       110        120        130        140        150
VEALQEFWQM KQSRGADLKN GALVVYEMVP SNSPPYVCYV TLPGGSCFGS 
       160        170        180        190        200
FQFCPTKAEA RRSAAKIALM NSVFNEHPSR RITDEFIEKS VSEALASFNG 
       210        220        230        240        250
NREEADNPNT GIGAFRFMLE SNKGKSMLEF QELMTVFQLL HWNGSLKAMR 
       260        270        280        290        300
ERQCSRQEVL AHYSHRALDD DIRHQMALDW VSREQSVPGA LSRELASTER 
       310        320        330 
ELDEARLAGK ELRFHKEKKD ILVLAAGQLG NMHSSNC

Length:337

Mass (Da):36,563

Last modified:March 1, 2003 - v1

Checksum:ⁱ0EC63B44AD5A744E

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC035727 mRNA Translation: AAH35727.1 CR627381 mRNA Translation: CAH10478.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS72873.1
NCBI Reference Sequences More...RefSeqⁱ	NP_714924.1, NM_153713.2
UniGeneⁱ	Hs.740619

Genome annotation databases

Ensemblⁱ	ENST00000604000; ENSP00000474487; ENSG00000271601
GeneIDⁱ	128077
KEGGⁱ	hsa:128077
UCSC genome browser More...UCSCⁱ	uc001enr.5 human

Protein	Similar proteins		Species	Score	Length
Q8IVB5	LIX1L isoform 1		PANTR		337
LIX1L isoform 1		PONAB		337
Limb and CNS expressed 1 like		PANPA		337
Limb and CNS expressed 1 like		GORGO		337

Protein	Similar proteins		Species	Score	Length
Q8IVB5	LIX1-like protein		MOUSE		337
Limb and CNS expressed 1 like		MONDO		339
UPI000C7A3442		SARHA		228
Limb and CNS expressed 1 like		MACMU		339
Lix1-like protein-like protein (Fragment)		MUSPF		196
+71

Protein	Similar proteins		Species	Score	Length
Q8IVB5	LIX1-like protein		MOUSE		337
Limb and CNS expressed 1 like		MONDO		339
UPI000C7A3442		SARHA		228
UPI000A281C74		PHACI		339
Limb and CNS expressed 1 like		MACMU		339
+147

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC035727 mRNA Translation: AAH35727.1 CR627381 mRNA Translation: CAH10478.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS72873.1
NCBI Reference Sequences More...RefSeqⁱ	NP_714924.1, NM_153713.2
UniGeneⁱ	Hs.740619

3D structure databases

ProteinModelPortalⁱ	Q8IVB5
SMRⁱ	Q8IVB5
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	126092, 9 interactors
IntActⁱ	Q8IVB5, 1 interactor
STRINGⁱ	9606.ENSP00000358314

PTM databases

iPTMnetⁱ	Q8IVB5
PhosphoSitePlusⁱ	Q8IVB5

Polymorphism and mutation databases

DMDMⁱ	74728055

DMDMⁱ

74728055

Proteomic databases

EPDⁱ	Q8IVB5
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q8IVB5
PaxDbⁱ	Q8IVB5
PeptideAtlas More...PeptideAtlasⁱ	Q8IVB5
PRIDEⁱ	Q8IVB5
ProteomicsDBⁱ	70679
TopDownProteomicsⁱ	Q8IVB5

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000604000; ENSP00000474487; ENSG00000271601
GeneIDⁱ	128077
KEGGⁱ	hsa:128077
UCSC genome browser More...UCSCⁱ	uc001enr.5 human

Organism-specific databases

CTDⁱ	128077
EuPathDBⁱ	HostDB:ENSG00000271601.3
GeneCardsⁱ	LIX1L
H-InvDBⁱ	HIX0023573
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:28715 LIX1L
Human Protein Atlas More...HPAⁱ	HPA063598
neXtProtⁱ	NX_Q8IVB5
Open Targets More...OpenTargetsⁱ	ENSG00000271601
PharmGKBⁱ	PA134915428
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	ENOG410IH13 Eukaryota ENOG410XRZR LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000005869
HOGENOMⁱ	HOG000237359
HOVERGENⁱ	HBG079509
InParanoidⁱ	Q8IVB5
KEGG Orthology (KO) More...KOⁱ	K16673
OMAⁱ	DWVNREQ
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0KAJ
PhylomeDBⁱ	Q8IVB5
TreeFamⁱ	TF324035

Miscellaneous databases

ChiTaRSⁱ	LIX1L human
GenomeRNAiⁱ	128077
Protein Ontology More...PROⁱ	PR:Q8IVB5

Gene expression databases

Bgeeⁱ	ENSG00000271601
CleanExⁱ	HS_LIX1L
Genevisibleⁱ	Q8IVB5 HS

Family and domain databases

InterProⁱ	View protein in InterPro IPR029270 LIX1
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF14954 LIX1, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	LIX1L_HUMAN
Accessionⁱ	Q8IVB5Primary (citable) accession number: Q8IVB5 Secondary accession number(s): Q6AI36
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	April 18, 2006
	Last sequence update:	March 1, 2003
	Last modified:	June 20, 2018
	This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

Human chromosome 1
Human chromosome 1: entries, gene names and cross-references to MIM
SIMILARITY comments
Index of protein domains and families

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q8IVB5 (LIX1L_HUMAN)

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LIX1-like protein

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Other locations

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

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Functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ