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UniProtKB - Q8IV50 (LYSM2_HUMAN)

Entry version 130 (02 Dec 2020)
Sequence version 1 (01 Mar 2003)
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Protein

LysM and putative peptidoglycan-binding domain-containing protein 2

Gene

LYSMD2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q8IV50

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
LysM and putative peptidoglycan-binding domain-containing protein 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:LYSMD2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 15

Organism-specific databases

Eukaryotic Pathogen and Host Database Resources

More...EuPathDBi		HostDB:ENSG00000140280.13

Human Gene Nomenclature Database

More...HGNCi		HGNC:28571, LYSMD2

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q8IV50

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000140280

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA142671494

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q8IV50, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		LYSMD2

Domain mapping of disease mutations (DMDM)

More...DMDMi		74728034

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedCombined sources
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002480022 – 215LysM and putative peptidoglycan-binding domain-containing protein 2Add BLAST214

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylalanineCombined sources1
Modified residuei5PhosphoserineCombined sources1
Modified residuei24PhosphoserineCombined sources1
Modified residuei33PhosphoserineCombined sources1
Modified residuei57PhosphoserineCombined sources1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q8IV50

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q8IV50

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q8IV50

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q8IV50

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q8IV50

PeptideAtlas

More...PeptideAtlasi		Q8IV50

PRoteomics IDEntifications database

More...PRIDEi		Q8IV50

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		70660 [Q8IV50-1]
70661 [Q8IV50-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q8IV50

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q8IV50

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000140280, Expressed in quadriceps femoris and 225 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q8IV50, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q8IV50, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000140280, Tissue enhanced (blood)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		129172, 18 interactors

Protein interaction database and analysis system

More...IntActi		Q8IV50, 15 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000267838

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q8IV50, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q8IV50

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini71 – 115LysMPROSITE-ProRule annotationAdd BLAST45

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502S0XR, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000160054

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_079453_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q8IV50

Identification of Orthologs from Complete Genome Data

More...OMAi		QDIEGPS

Database of Orthologous Groups

More...OrthoDBi		1553362at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q8IV50

TreeFam database of animal gene trees

More...TreeFami		TF318444

Family and domain databases

Conserved Domains Database

More...CDDi		cd00118, LysM, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.10.350.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR018392, LysM_dom
IPR036779, LysM_dom_sf

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01476, LysM, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00257, LysM, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51782, LYSM, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8IV50-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MADSSPALSL REGGPRAPRP SAPSPPPRSR SGSESEEAEL SLSLARTKTR 
        60         70         80         90        100
SYGSTASVRA PLGAGVIERH VEHRVRAGDT LQGIALKYGV TMEQIKRANK 
       110        120        130        140        150
LFTNDCIFLK KTLNIPVISE KPLLFNGLNS IDSPENETAD NSFSQEEEPV 
       160        170        180        190        200
VAGEDLPPPS PQESDVQPVQ PEEVSARDFL QRLDLQIKLS TQAAKKLKEE 
       210 
SRDEESPYAT SLYHS
Length:215
Mass (Da):23,463
Last modified:March 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA87E666478E903AC
GO
Isoform 2 (identifier: Q8IV50-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-91: Missing.

Show »
Length:124
Mass (Da):13,974
Checksum:iAF3AEAC87C5E1280
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H0YK98H0YK98_HUMAN
LysM and putative peptidoglycan-bin...
LYSMD2
108Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_027198107I → V. Corresponds to variant dbSNP:rs3751593Ensembl.1
Natural variantiVAR_027199164S → F. Corresponds to variant dbSNP:rs7168775Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0201231 – 91Missing in isoform 2. 1 PublicationAdd BLAST91

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AY125955 mRNA Translation: AAM94507.1
BC022075 mRNA Translation: AAH22075.1
BC033515 mRNA Translation: AAH33515.1
CR936638 mRNA Translation: CAI56778.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS10143.1 [Q8IV50-1]
CCDS45259.1 [Q8IV50-2]

NCBI Reference Sequences

More...RefSeqi		NP_001137389.1, NM_001143917.1 [Q8IV50-2]
NP_699205.1, NM_153374.2 [Q8IV50-1]
XP_016877546.1, XM_017022057.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000267838; ENSP00000267838; ENSG00000140280 [Q8IV50-1]
ENST00000454181; ENSP00000410424; ENSG00000140280 [Q8IV50-2]
ENST00000560491; ENSP00000453933; ENSG00000140280 [Q8IV50-2]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		256586

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:256586

UCSC genome browser

More...UCSCi		uc002abi.4, human [Q8IV50-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY125955 mRNA Translation: AAM94507.1
BC022075 mRNA Translation: AAH22075.1
BC033515 mRNA Translation: AAH33515.1
CR936638 mRNA Translation: CAI56778.1
CCDSiCCDS10143.1 [Q8IV50-1]
CCDS45259.1 [Q8IV50-2]
RefSeqiNP_001137389.1, NM_001143917.1 [Q8IV50-2]
NP_699205.1, NM_153374.2 [Q8IV50-1]
XP_016877546.1, XM_017022057.1

3D structure databases

SMRiQ8IV50
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi129172, 18 interactors
IntActiQ8IV50, 15 interactors
STRINGi9606.ENSP00000267838

PTM databases

iPTMnetiQ8IV50
PhosphoSitePlusiQ8IV50

Polymorphism and mutation databases

BioMutaiLYSMD2
DMDMi74728034

Proteomic databases

EPDiQ8IV50
jPOSTiQ8IV50
MassIVEiQ8IV50
MaxQBiQ8IV50
PaxDbiQ8IV50
PeptideAtlasiQ8IV50
PRIDEiQ8IV50
ProteomicsDBi70660 [Q8IV50-1]
70661 [Q8IV50-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		24890, 42 antibodies

The DNASU plasmid repository

More...DNASUi		256586

Genome annotation databases

EnsembliENST00000267838; ENSP00000267838; ENSG00000140280 [Q8IV50-1]
ENST00000454181; ENSP00000410424; ENSG00000140280 [Q8IV50-2]
ENST00000560491; ENSP00000453933; ENSG00000140280 [Q8IV50-2]
GeneIDi256586
KEGGihsa:256586
UCSCiuc002abi.4, human [Q8IV50-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		256586
EuPathDBiHostDB:ENSG00000140280.13

GeneCards: human genes, protein and diseases

More...GeneCardsi		LYSMD2
HGNCiHGNC:28571, LYSMD2
HPAiENSG00000140280, Tissue enhanced (blood)
neXtProtiNX_Q8IV50
OpenTargetsiENSG00000140280
PharmGKBiPA142671494

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG502S0XR, Eukaryota
GeneTreeiENSGT00940000160054
HOGENOMiCLU_079453_1_0_1
InParanoidiQ8IV50
OMAiQDIEGPS
OrthoDBi1553362at2759
PhylomeDBiQ8IV50
TreeFamiTF318444

Enzyme and pathway databases

PathwayCommonsiQ8IV50

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		256586, 3 hits in 845 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		256586
PharosiQ8IV50, Tdark

Protein Ontology

More...PROi		PR:Q8IV50
RNActiQ8IV50, protein

Gene expression databases

BgeeiENSG00000140280, Expressed in quadriceps femoris and 225 other tissues
ExpressionAtlasiQ8IV50, baseline and differential
GenevisibleiQ8IV50, HS

Family and domain databases

CDDicd00118, LysM, 1 hit
Gene3Di3.10.350.10, 1 hit
InterProiView protein in InterPro
IPR018392, LysM_dom
IPR036779, LysM_dom_sf
PfamiView protein in Pfam
PF01476, LysM, 1 hit
SMARTiView protein in SMART
SM00257, LysM, 1 hit
PROSITEiView protein in PROSITE
PS51782, LYSM, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiLYSM2_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8IV50
Secondary accession number(s): Q5CZ88, Q8WTV3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 5, 2006
Last sequence update: March 1, 2003
Last modified: December 2, 2020
This is version 130 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  2. Human chromosome 15
    Human chromosome 15: entries, gene names and cross-references to MIM
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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