CLEC10A

Functionⁱ

Probable role in regulating adaptive and innate immune responses. Binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. These sugar moieties are known as Tn-Ag and are expressed in a variety of carcinoma cells.1 Publication

GO - Molecular functionⁱ

carbohydrate binding
Source: ProtInc
Traceable author statementⁱ
- 8598452

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

adaptive immune response Source: UniProtKB-KW
endocytosis Source: UniProtKB-KW
innate immune response Source: UniProtKB-KW
stimulatory C-type lectin receptor signaling pathway Source: Reactome

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Biological process	Adaptive immunity, Endocytosis, Immunity, Innate immunity
Ligand	Lectin

Enzyme and pathway databases

Reactomeⁱ	R-HSA-5621480 Dectin-2 family

Reactomeⁱ

R-HSA-5621480 Dectin-2 family

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: C-type lectin domain family 10 member A Alternative name(s): C-type lectin superfamily member 14 Macrophage lectin 2 CD_antigen: CD301
Gene namesⁱ	Name:CLEC10A Synonyms:CLECSF13, CLECSF14, HML
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 17

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000132514.13
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:16916 CLEC10A
MIMⁱ	605999 gene
neXtProtⁱ	NX_Q8IUN9

Topology

Feature key	Position(s)	DescriptionActions	Length
Topological domainⁱ	1 – 39	CytoplasmicSequence analysisAdd BLAST	39
Transmembraneⁱ	40 – 60	Helical; Signal-anchor for type II membrane proteinSequence analysisAdd BLAST	21
Topological domainⁱ	61 – 316	ExtracellularSequence analysisAdd BLAST	256

Keywords - Cellular componentⁱ

Membrane

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	10462
Open Targets More...OpenTargetsⁱ	ENSG00000132514
PharmGKBⁱ	PA134975011

Polymorphism and mutation databases

BioMutaⁱ	CLEC10A
DMDMⁱ	59797948

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000046639	1 – 316	C-type lectin domain family 10 member AAdd BLAST		316

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Glycosylationⁱ	78	N-linked (GlcNAc...) asparagineSequence analysis	1
Glycosylationⁱ	173	N-linked (GlcNAc...) asparagineSequence analysis	1
Disulfide bondⁱ	181 ↔ 192	PROSITE-ProRule annotation
Disulfide bondⁱ	209 ↔ 304	PROSITE-ProRule annotation
Disulfide bondⁱ	282 ↔ 296	PROSITE-ProRule annotation

Keywords - PTMⁱ

Disulfide bond, Glycoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q8IUN9
PaxDbⁱ	Q8IUN9
PeptideAtlas More...PeptideAtlasⁱ	Q8IUN9
PRIDEⁱ	Q8IUN9
ProteomicsDBⁱ	70588 70589 [Q8IUN9-2] 70590 [Q8IUN9-3]

PTM databases

iPTMnetⁱ	Q8IUN9
PhosphoSitePlusⁱ	Q8IUN9

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000132514 Expressed in 159 organ(s), highest expression level in oocyte
CleanExⁱ	HS_CLEC10A
ExpressionAtlasⁱ	Q8IUN9 baseline and differential
Genevisibleⁱ	Q8IUN9 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA021937

HPAⁱ

HPA021937

Interactionⁱ

Protein-protein interaction databases

BioGridⁱ	115725, 2 interactors
IntActⁱ	Q8IUN9, 25 interactors
STRINGⁱ	9606.ENSP00000254868

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q8IUN9
SMRⁱ	Q8IUN9
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	188 – 305	C-type lectinPROSITE-ProRule annotationAdd BLAST		118

Coiled coil

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Coiled coilⁱ	85 – 176	Sequence analysisAdd BLAST		92

Motif

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Motifⁱ	5 – 8	Endocytosis signalSequence analysis		4

Keywords - Domainⁱ

Coiled coil, Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGⁱ	ENOG410IS30 Eukaryota ENOG410ZDP5 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000118924
HOGENOMⁱ	HOG000034093
HOVERGENⁱ	HBG000270
InParanoidⁱ	Q8IUN9
KEGG Orthology (KO) More...KOⁱ	K06721
OMAⁱ	HPDGRWN
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G062T
PhylomeDBⁱ	Q8IUN9
TreeFamⁱ	TF352155

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd03590 CLECT_DC-SIGN_like, 1 hit
Gene3Dⁱ	3.10.100.10, 1 hit
InterProⁱ	View protein in InterPro IPR001304 C-type_lectin-like IPR016186 C-type_lectin-like/link_sf IPR018378 C-type_lectin_CS IPR033989 CD209-like_CTLD IPR016187 CTDL_fold
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00059 Lectin_C, 1 hit
SMARTⁱ	View protein in SMART SM00034 CLECT, 1 hit
SUPFAMⁱ	SSF56436 SSF56436, 1 hit
PROSITEⁱ	View protein in PROSITE PS00615 C_TYPE_LECTIN_1, 1 hit PS50041 C_TYPE_LECTIN_2, 1 hit

Sequences (3+)ⁱ

Sequence statusⁱ: Complete.

This entry describes 3 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 3 described isoforms and 2 potential isoforms that are computationally mapped.Show all Align All

Isoform 1 (identifier: Q8IUN9-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MTRTYENFQY LENKVKVQGF KNGPLPLQSL LQRLCSGPCH LLLSLGLGLL 
        60         70         80         90        100
LLVIICVVGF QNSKFQRDLV TLRTDFSNFT SNTVAEIQAL TSQGSSLEET 
       110        120        130        140        150
IASLKAEVEG FKQERQAGVS ELQEHTTQKA HLGHCPHCPS VCVPVHSEML 
       160        170        180        190        200
LRVQQLVQDL KKLTCQVATL NNNASTEGTC CPVNWVEHQD SCYWFSHSGM 
       210        220        230        240        250
SWAEAEKYCQ LKNAHLVVIN SREEQNFVQK YLGSAYTWMG LSDPEGAWKW 
       260        270        280        290        300
VDGTDYATGF QNWKPGQPDD WQGHGLGGGE DCAHFHPDGR WNDDVCQRPY 
       310 
HWVCEAGLGQ TSQESH

Length:316

Mass (Da):35,446

Last modified:March 1, 2003 - v1

Checksum:ⁱD3B7193E2E1F58AF

GO

Isoform 2 (identifier: Q8IUN9-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
118-144: Missing.
173-173: N → NGEE

« Hide

        10         20         30         40         50
MTRTYENFQY LENKVKVQGF KNGPLPLQSL LQRLCSGPCH LLLSLGLGLL 
        60         70         80         90        100
LLVIICVVGF QNSKFQRDLV TLRTDFSNFT SNTVAEIQAL TSQGSSLEET 
       110        120        130        140        150
IASLKAEVEG FKQERQAVHS EMLLRVQQLV QDLKKLTCQV ATLNNNGEEA 
       160        170        180        190        200
STEGTCCPVN WVEHQDSCYW FSHSGMSWAE AEKYCQLKNA HLVVINSREE 
       210        220        230        240        250
QNFVQKYLGS AYTWMGLSDP EGAWKWVDGT DYATGFQNWK PGQPDDWQGH 
       260        270        280        290 
GLGGGEDCAH FHPDGRWNDD VCQRPYHWVC EAGLGQTSQE SH

Show »

Length:292

Mass (Da):32,884

Checksum:ⁱ5472EFF9EBC7AC19

GO

Isoform 3 (identifier: Q8IUN9-3) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
     118-144: Missing.
     226-283: NFVQKYLGSA...HGLGGGEDCA → VRASGTQFLR...IQRNISKLLS
     284-316: Missing.

« Hide

        10         20         30         40         50
MTRTYENFQY LENKVKVQGF KNGPLPLQSL LQRLCSGPCH LLLSLGLGLL 
        60         70         80         90        100
LLVIICVVGF QNSKFQRDLV TLRTDFSNFT SNTVAEIQAL TSQGSSLEET 
       110        120        130        140        150
IASLKAEVEG FKQERQAVHS EMLLRVQQLV QDLKKLTCQV ATLNNNASTE 
       160        170        180        190        200
GTCCPVNWVE HQDSCYWFSH SGMSWAEAEK YCQLKNAHLV VINSREEQVR 
       210        220        230        240        250
ASGTQFLRHV PFREMVLKLG RTLESSGSFQ NDCHLCHTLR DLIGLSIQRN 

ISKLLS

Show »

Length:256

Mass (Da):28,877

Checksum:ⁱBEB86B3B5CC8DCD0

GO

Computationally mapped potential isoform sequencesⁱ

There are 2 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

J3KR22	J3KR22_HUMAN	C-type lectin domain family 10 memb... C-type lectin domain family 10 member A	CLEC10A	289	Annotation score:
I3NI09	I3NI09_HUMAN	C-type lectin domain family 10 memb... C-type lectin domain family 10 member A	CLEC10A	136	Annotation score:

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	112	K → R in AAH27858 (PubMed:15489334).Curated		1

Natural variant

Feature key	Position(s)	DescriptionActions	Length
Natural variantⁱVAR_021262	35	C → R1 PublicationCorresponds to variant dbSNP:rs90951Ensembl.	1
Natural variantⁱVAR_050113	73	R → K. Corresponds to variant dbSNP:rs16956478Ensembl.	1
Natural variantⁱVAR_050114	100	T → M. Corresponds to variant dbSNP:rs35318160Ensembl.	1
Natural variantⁱVAR_050115	203	A → G. Corresponds to variant dbSNP:rs35101468Ensembl.	1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Length
Alternative sequenceⁱVSP_012848	118 – 144	Missing in isoform 2 and isoform 3. 3 PublicationsAdd BLAST	27
Alternative sequenceⁱVSP_012849	173	N → NGEE in isoform 2. 1 Publication	1
Alternative sequenceⁱVSP_012850	226 – 283	NFVQK…GEDCA → VRASGTQFLRHVPFREMVLK LGRTLESSGSFQNDCHLCHT LRDLIGLSIQRNISKLLS in isoform 3. 2 PublicationsAdd BLAST	58
Alternative sequenceⁱVSP_012851	284 – 316	Missing in isoform 3. 2 PublicationsAdd BLAST	33

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	D50532 mRNA Translation: BAA09101.1 AK292363 mRNA Translation: BAF85052.1 BC027858 mRNA Translation: AAH27858.1 BC039011 mRNA Translation: AAH39011.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS11087.1 [Q8IUN9-1] CCDS45597.1 [Q8IUN9-2]
NCBI Reference Sequences More...RefSeqⁱ	NP_006335.2, NM_006344.3 [Q8IUN9-2] NP_878910.1, NM_182906.3 [Q8IUN9-1]
UniGeneⁱ	Hs.54403

Genome annotation databases

Ensemblⁱ	ENST00000254868; ENSP00000254868; ENSG00000132514 [Q8IUN9-1] ENST00000571664; ENSP00000460252; ENSG00000132514 [Q8IUN9-2] ENST00000576617; ENSP00000458728; ENSG00000132514 [Q8IUN9-3]
GeneIDⁱ	10462
KEGGⁱ	hsa:10462
UCSC genome browser More...UCSCⁱ	uc002gej.4 human [Q8IUN9-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing, Polymorphism

Similar proteinsⁱ

90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q8IUN9	C-type lectin domain containing 10A		PANTR		316	UniRef90_Q8IUN9
C-type lectin domain containing 10A		PONAB		316
Uncharacterized protein		PANPA		316
Uncharacterized protein		NOMLE		316
UPI0001C58462		HUMAN		319
+4
Q8IUN9-2	CLEC10A isoform 2		PONAB		292	UniRef90_Q8IUN9-2
CLEC10A isoform 2		PANTR		292
C-type lectin domain family 10 member A		HUMAN		289
UPI00020ADDD3		NOMLE		292
UPI0002743C0D		PANPA		292
+3
Q8IUN9-3	C-type lectin domain family 10, member A, isoform CRA_c		HUMAN		256	UniRef90_Q8IUN9-3
CLEC10A isoform 4		PONAB		256
CLEC10A isoform 4		PANTR		256

Protein	Similar proteins		Species	Score	Length	Source
Q8IUN9	C-type lectin domain containing 10A		PONAB		316	UniRef50_Q8IUN9
Uncharacterized protein		NOMLE		316
Uncharacterized protein		PANPA		316
C-type lectin domain containing 10A		PANTR		316
Uncharacterized protein		PROCO		316
+33
Q8IUN9-2	CLEC10A isoform 2		PONAB		292	UniRef50_Q8IUN9-2
CLEC10A isoform 2		PANTR		292
C-type lectin domain family 10 member A		HUMAN		289
Uncharacterized protein		PROCO		291
C-type lectin domain family 10 member A		TARSY		293
+30
Q8IUN9-3	CLEC10A isoform 4		PONAB		256	UniRef50_Q8IUN9-3
C-type lectin domain family 10, member A, isoform CRA_c		HUMAN		256
CLEC10A isoform 4		PANTR		256
C-type lectin domain containing 10A		AOTNA		242
Uncharacterized protein		PROCO		231
+5

Cross-referencesⁱ

Web resourcesⁱ

Functional Glycomics Gateway - Glycan Binding

MGL

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	D50532 mRNA Translation: BAA09101.1 AK292363 mRNA Translation: BAF85052.1 BC027858 mRNA Translation: AAH27858.1 BC039011 mRNA Translation: AAH39011.1
CCDSⁱ	CCDS11087.1 [Q8IUN9-1] CCDS45597.1 [Q8IUN9-2]
RefSeqⁱ	NP_006335.2, NM_006344.3 [Q8IUN9-2] NP_878910.1, NM_182906.3 [Q8IUN9-1]
UniGeneⁱ	Hs.54403

3D structure databases

ProteinModelPortalⁱ	Q8IUN9
SMRⁱ	Q8IUN9
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	115725, 2 interactors
IntActⁱ	Q8IUN9, 25 interactors
STRINGⁱ	9606.ENSP00000254868

PTM databases

iPTMnetⁱ	Q8IUN9
PhosphoSitePlusⁱ	Q8IUN9

Polymorphism and mutation databases

BioMutaⁱ	CLEC10A
DMDMⁱ	59797948

Proteomic databases

MaxQBⁱ	Q8IUN9
PaxDbⁱ	Q8IUN9
PeptideAtlasⁱ	Q8IUN9
PRIDEⁱ	Q8IUN9
ProteomicsDBⁱ	70588 70589 [Q8IUN9-2] 70590 [Q8IUN9-3]

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000254868; ENSP00000254868; ENSG00000132514 [Q8IUN9-1] ENST00000571664; ENSP00000460252; ENSG00000132514 [Q8IUN9-2] ENST00000576617; ENSP00000458728; ENSG00000132514 [Q8IUN9-3]
GeneIDⁱ	10462
KEGGⁱ	hsa:10462
UCSCⁱ	uc002gej.4 human [Q8IUN9-1]

Organism-specific databases

CTDⁱ	10462
DisGeNETⁱ	10462
EuPathDBⁱ	HostDB:ENSG00000132514.13
GeneCardsⁱ	CLEC10A
HGNCⁱ	HGNC:16916 CLEC10A
HPAⁱ	HPA021937
MIMⁱ	605999 gene
neXtProtⁱ	NX_Q8IUN9
OpenTargetsⁱ	ENSG00000132514
PharmGKBⁱ	PA134975011
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	ENOG410IS30 Eukaryota ENOG410ZDP5 LUCA
GeneTreeⁱ	ENSGT00760000118924
HOGENOMⁱ	HOG000034093
HOVERGENⁱ	HBG000270
InParanoidⁱ	Q8IUN9
KOⁱ	K06721
OMAⁱ	HPDGRWN
OrthoDBⁱ	EOG091G062T
PhylomeDBⁱ	Q8IUN9
TreeFamⁱ	TF352155

Enzyme and pathway databases

Reactomeⁱ	R-HSA-5621480 Dectin-2 family

Reactomeⁱ

R-HSA-5621480 Dectin-2 family

Miscellaneous databases

GeneWikiⁱ	CLEC10A
GenomeRNAiⁱ	10462
Protein Ontology More...PROⁱ	PR:Q8IUN9
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000132514 Expressed in 159 organ(s), highest expression level in oocyte
CleanExⁱ	HS_CLEC10A
ExpressionAtlasⁱ	Q8IUN9 baseline and differential
Genevisibleⁱ	Q8IUN9 HS

Family and domain databases

CDDⁱ	cd03590 CLECT_DC-SIGN_like, 1 hit
Gene3Dⁱ	3.10.100.10, 1 hit
InterProⁱ	View protein in InterPro IPR001304 C-type_lectin-like IPR016186 C-type_lectin-like/link_sf IPR018378 C-type_lectin_CS IPR033989 CD209-like_CTLD IPR016187 CTDL_fold
Pfamⁱ	View protein in Pfam PF00059 Lectin_C, 1 hit
SMARTⁱ	View protein in SMART SM00034 CLECT, 1 hit
SUPFAMⁱ	SSF56436 SSF56436, 1 hit
PROSITEⁱ	View protein in PROSITE PS00615 C_TYPE_LECTIN_1, 1 hit PS50041 C_TYPE_LECTIN_2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	CLC10_HUMAN
Accessionⁱ	Q8IUN9Primary (citable) accession number: Q8IUN9 Secondary accession number(s): A8K8J8, Q14538, Q6PIW3
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	February 15, 2005
	Last sequence update:	March 1, 2003
	Last modified:	September 12, 2018
	This is version 129 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

Human chromosome 17
Human chromosome 17: entries, gene names and cross-references to MIM
Human cell differentiation molecules
CD nomenclature of surface proteins of human leucocytes and list of entries
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

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UniProtKB - Q8IUN9 (CLC10_HUMAN)

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C-type lectin domain family 10 member A

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Other locations

Plasma Membrane

Other locations

Topology

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Coiled coil

Motif

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Experimental Info

Natural variant

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross_references_section">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Web resourcesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ