Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

UniProtKB - Q8IUL8 (CILP2_HUMAN)

Entry version 145 (07 Apr 2021)
Sequence version 2 (05 Jul 2005)
Previous versions | rss
Add a publicationFeedback
Protein

Cartilage intermediate layer protein 2

Gene

CILP2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May play a role in cartilage scaffolding.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q8IUL8

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cartilage intermediate layer protein 2
Short name:
CILP-2
Cleaved into the following 2 chains:
Cartilage intermediate layer protein 2 C1
Cartilage intermediate layer protein 2 C2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CILP2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:24213, CILP2

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		612419, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q8IUL8

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000160161.9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Extracellular matrix, Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		148113

Open Targets

More...OpenTargetsi		ENSG00000160161

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134970563

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q8IUL8, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		CILP2

Domain mapping of disease mutations (DMDM)

More...DMDMi		68565198

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 20Sequence analysisAdd BLAST20
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000001467821 – 1156Cartilage intermediate layer protein 2Add BLAST1136
ChainiPRO_000001467921 – ?709Cartilage intermediate layer protein 2 C1Sequence analysisAdd BLAST689
ChainiPRO_0000014680?710 – 1156Cartilage intermediate layer protein 2 C2Sequence analysisAdd BLAST447

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi158 ↔ 191By similarity
Disulfide bondi162 ↔ 196By similarity
Disulfide bondi173 ↔ 181By similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi276N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi308N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi313 ↔ 359By similarity
Glycosylationi329N-linked (GlcNAc...) asparagineSequence analysis1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

May be cleaved into 2 chains possibly by a furin-like protease upon or preceding secretion.By similarity

Keywords - PTMi

Cleavage on pair of basic residues, Disulfide bond, Glycoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q8IUL8

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q8IUL8

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q8IUL8

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q8IUL8

PeptideAtlas

More...PeptideAtlasi		Q8IUL8

PRoteomics IDEntifications database

More...PRIDEi		Q8IUL8

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		70584

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...GlyGeni		Q8IUL8, 3 sites

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q8IUL8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q8IUL8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in articular chondrocytes but not in knee meniscal cartilage cells (PubMed:12746903). Localizes to the intermediate to deep zone of articular cartilage (PubMed:21880736).2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000160161, Expressed in tendon of biceps brachii and 104 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q8IUL8, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q8IUL8, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000160161, Tissue enhanced (ovary, testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		127119, 6 interactors

Protein interaction database and analysis system

More...IntActi		Q8IUL8, 4 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000291495

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q8IUL8, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q8IUL8

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini146 – 197TSP type-1PROSITE-ProRule annotationAdd BLAST52
Domaini292 – 376Ig-like C2-typeAdd BLAST85

Keywords - Domaini

Immunoglobulin domain, Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502QQ8H, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000008152

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q8IUL8

Database of Orthologous Groups

More...OrthoDBi		629181at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q8IUL8

TreeFam database of animal gene trees

More...TreeFami		TF330132

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.20.100.10, 1 hit
2.60.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR008969, CarboxyPept-like_regulatory
IPR039675, CILP1/CILP2
IPR007110, Ig-like_dom
IPR036179, Ig-like_dom_sf
IPR013783, Ig-like_fold
IPR003599, Ig_sub
IPR003598, Ig_sub2
IPR000884, TSP1_rpt
IPR036383, TSP1_rpt_sf
IPR025155, WxxW_domain

The PANTHER Classification System

More...PANTHERi		PTHR15031, PTHR15031, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF13330, Mucin2_WxxW, 1 hit
PF00090, TSP_1, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00409, IG, 1 hit
SM00408, IGc2, 1 hit
SM00209, TSP1, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48726, SSF48726, 1 hit
SSF49464, SSF49464, 1 hit
SSF82895, SSF82895, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50835, IG_LIKE, 1 hit
PS50092, TSP1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q8IUL8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASLLPLLCL CVVAAHLAGA RDATPTEEPM ATALGLERRS VYTGQPSPAL 
        60         70         80         90        100
EDWEEASEWT SWFNVDHPGG DGDFESLAAI RFYYGPARVC PRPLALEART 
       110        120        130        140        150
TDWALPSAVG ERVHLNPTRG FWCLNREQPR GRRCSNYHVR FRCPLEASWG 
       160        170        180        190        200
AWGPWGPCSG SCGPGRRLRR RHCPSPAGDA CPGRPLEAQK CVRPRCPGCS 
       210        220        230        240        250
LDTCECPDHI LLGSVVTPSG QPLLGARVSL RDQPGTVATS DAHGTFRVPG 
       260        270        280        290        300
VCADSRANIR AQMDGFSAGE AQAQANGSIS VVTIILDKLE KPYLVKHPES 
       310        320        330        340        350
RVREAGQNVT FCCKASGTPM PKKYSWFHNG TLLDRRAHGY GAHLELRGLR 
       360        370        380        390        400
PDQAGIYHCK AWNEAGAVRS GTARLTVLAP GQPACDPRPR EYLIKLPEDC 
       410        420        430        440        450
GQPGSGPAYL DVGLCPDTRC PSLAGSSPRC GDASSRCCSV RRLERREIHC 
       460        470        480        490        500
PGYVLPVKVV AECGCQKCLP PRGLVRGRVV AADSGEPLRF ARILLGQEPI 
       510        520        530        540        550
GFTAYQGDFT IEVPPSTQRL VVTFVDPSGE FMDAVRVLPF DPRGAGVYHE 
       560        570        580        590        600
VKAMRKKAPV ILHTSQSNTI PLGELEDEAP LGELVLPSGA FRRADGKPYS 
       610        620        630        640        650
GPVEARVTFV DPRDLTSAAS APSDLRFVDS DGELAPLRTY GMFSVDLRAP 
       660        670        680        690        700
GSAEQLQVGP VAVRVAASQI HMPGHVEALK LWSLNPETGL WEEESGFRRE 
       710        720        730        740        750
GSSGPRVRRE ERVFLVGNVE IRERRLFNLD VPERRRCFVK VRAYANDKFT 
       760        770        780        790        800
PSEQVEGVVV TLVNLEPAPG FSANPRAWGR FDSAVTGPNG ACLPAFCDAD 
       810        820        830        840        850
RPDAYTALVT ATLGGEELEP APSLPRPLPA TVGVTQPYLD RLGYRRTDHD 
       860        870        880        890        900
DPAFKRNGFR INLAKPRPGD PAEANGPVYP WRSLRECQGA PVTASHFRFA 
       910        920        930        940        950
RVEADKYEYN VVPFREGTPA SWTGDLLAWW PNPQEFRACF LKVKIQGPQE 
       960        970        980        990       1000
YMVRSHNAGG SHPRTRGQLY GLRDARSVRD PERPGTSAAC VEFKCSGMLF 
      1010       1020       1030       1040       1050
DQRQVDRTLV TIMPQGSCRR VAVNGLLRDY LTRHPPPVPA EDPAAFSMLA 
      1060       1070       1080       1090       1100
PLDPLGHNYG VYTVTDQSPR LAKEIAIGRC FDGSSDGFSR EMKADAGTAV 
      1110       1120       1130       1140       1150
TFQCREPPAG RPSLFQRLLE SPATALGDIR REMSEAAQAQ ARASGPLRTR 

RGRVRQ
Length:1,156
Mass (Da):126,291
Last modified:July 5, 2005 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iCE4AAB47841C07F9
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
K7EPJ4K7EPJ4_HUMAN
Cartilage intermediate layer protei...
CILP2 hCG_38566
1,162Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti768A → G in AAN17826 (PubMed:12746903).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF542080 mRNA Translation: AAN17826.1
BC018939 mRNA Translation: AAH18939.2
BC034926 mRNA Translation: AAH34926.2

The Consensus CDS (CCDS) project

More...CCDSi		CCDS12405.1

NCBI Reference Sequences

More...RefSeqi		NP_694953.2, NM_153221.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000291495; ENSP00000291495; ENSG00000160161

Database of genes from NCBI RefSeq genomes

More...GeneIDi		148113

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:148113

UCSC genome browser

More...UCSCi		uc002nmv.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF542080 mRNA Translation: AAN17826.1
BC018939 mRNA Translation: AAH18939.2
BC034926 mRNA Translation: AAH34926.2
CCDSiCCDS12405.1
RefSeqiNP_694953.2, NM_153221.2

3D structure databases

SMRiQ8IUL8
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi127119, 6 interactors
IntActiQ8IUL8, 4 interactors
STRINGi9606.ENSP00000291495

PTM databases

GlyGeniQ8IUL8, 3 sites
iPTMnetiQ8IUL8
PhosphoSitePlusiQ8IUL8

Genetic variation databases

BioMutaiCILP2
DMDMi68565198

Proteomic databases

EPDiQ8IUL8
jPOSTiQ8IUL8
MassIVEiQ8IUL8
PaxDbiQ8IUL8
PeptideAtlasiQ8IUL8
PRIDEiQ8IUL8
ProteomicsDBi70584

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		48010, 81 antibodies

Genome annotation databases

EnsembliENST00000291495; ENSP00000291495; ENSG00000160161
GeneIDi148113
KEGGihsa:148113
UCSCiuc002nmv.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		148113
DisGeNETi148113

GeneCards: human genes, protein and diseases

More...GeneCardsi		CILP2
HGNCiHGNC:24213, CILP2
HPAiENSG00000160161, Tissue enhanced (ovary, testis)
MIMi612419, gene
neXtProtiNX_Q8IUL8
OpenTargetsiENSG00000160161
PharmGKBiPA134970563
VEuPathDBiHostDB:ENSG00000160161.9

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG502QQ8H, Eukaryota
GeneTreeiENSGT00390000008152
InParanoidiQ8IUL8
OrthoDBi629181at2759
PhylomeDBiQ8IUL8
TreeFamiTF330132

Enzyme and pathway databases

PathwayCommonsiQ8IUL8

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		148113, 12 hits in 985 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		148113
PharosiQ8IUL8, Tbio

Protein Ontology

More...PROi		PR:Q8IUL8
RNActiQ8IUL8, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000160161, Expressed in tendon of biceps brachii and 104 other tissues
ExpressionAtlasiQ8IUL8, baseline and differential
GenevisibleiQ8IUL8, HS

Family and domain databases

Gene3Di2.20.100.10, 1 hit
2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR008969, CarboxyPept-like_regulatory
IPR039675, CILP1/CILP2
IPR007110, Ig-like_dom
IPR036179, Ig-like_dom_sf
IPR013783, Ig-like_fold
IPR003599, Ig_sub
IPR003598, Ig_sub2
IPR000884, TSP1_rpt
IPR036383, TSP1_rpt_sf
IPR025155, WxxW_domain
PANTHERiPTHR15031, PTHR15031, 1 hit
PfamiView protein in Pfam
PF13330, Mucin2_WxxW, 1 hit
PF00090, TSP_1, 1 hit
SMARTiView protein in SMART
SM00409, IG, 1 hit
SM00408, IGc2, 1 hit
SM00209, TSP1, 1 hit
SUPFAMiSSF48726, SSF48726, 1 hit
SSF49464, SSF49464, 1 hit
SSF82895, SSF82895, 1 hit
PROSITEiView protein in PROSITE
PS50835, IG_LIKE, 1 hit
PS50092, TSP1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCILP2_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8IUL8
Secondary accession number(s): Q6NV88, Q8N4A6, Q8WV21
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: July 5, 2005
Last modified: April 7, 2021
This is version 145 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again