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Protein
Submitted name:

Tenzing norgay, isoform C

Gene

tzn

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione Source: InterPro
  • response to hypoxia Source: FlyBase

Keywordsi

Molecular functionHydrolaseImported

Enzyme and pathway databases

ReactomeiR-DME-70268 Pyruvate metabolism

Names & Taxonomyi

Protein namesi
Submitted name:
Tenzing norgay, isoform CImported (EC:3.1.2.6Imported)
Gene namesi
Name:tznImported
Synonyms:Dmel\CG4365Imported
ORF Names:CG4365Imported, Dmel_CG4365Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3L

Organism-specific databases

FlyBaseiFBgn0037024 tzn

PTM / Processingi

Proteomic databases

PaxDbiQ8IPU3
PRIDEiQ8IPU3

Expressioni

Gene expression databases

BgeeiFBgn0037024
ExpressionAtlasiQ8IPU3 baseline and differential
GenevisibleiQ8IPU3 DM

Interactioni

Protein-protein interaction databases

IntActiQ8IPU3, 1 interactor
STRINGi7227.FBpp0077912

Structurei

3D structure databases

ProteinModelPortaliQ8IPU3
SMRiQ8IPU3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini100 – 263Lactamase_BInterPro annotationAdd BLAST164

Phylogenomic databases

eggNOGiKOG0813 Eukaryota
COG0491 LUCA
GeneTreeiENSGT00530000063033
InParanoidiQ8IPU3
OrthoDBiEOG091G0E58
PhylomeDBiQ8IPU3

Family and domain databases

CDDicd07723 hydroxyacylglutathione_hydrola, 1 hit
Gene3Di3.60.15.10, 1 hit
HAMAPiMF_01374 Glyoxalase_2, 1 hit
InterProiView protein in InterPro
IPR035680 Clx_II_MBL
IPR032282 HAGH_C
IPR017782 Hydroxyacylglutathione_Hdrlase
IPR001279 Metallo-B-lactamas
IPR036866 RibonucZ/Hydroxyglut_hydro
PfamiView protein in Pfam
PF16123 HAGH_C, 1 hit
PF00753 Lactamase_B, 1 hit
SMARTiView protein in SMART
SM00849 Lactamase_B, 1 hit
SUPFAMiSSF56281 SSF56281, 1 hit
TIGRFAMsiTIGR03413 GSH_gloB, 1 hit

Sequencei

Sequence statusi: Complete.

Q8IPU3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLASAWRSVA TSVETQLTAT YFRGSSSNPT LLLRSWRTIP RADAPGFGAI
60 70 80 90 100
RRRFLAVPVI CPSLVKLQKL RKVGFRGMHS TLEDVQLEGM EIKILPALQD
110 120 130 140 150
NYMYLIVDTK TREAAVVDPV EPELVIKTVQ EQQLTLSKVL TTHHHWDHAG
160 170 180 190 200
GNEKLLKLWE KELDVYGGDD RIGALNKKVQ QDDTFTIGGL HVKCLSTPCH
210 220 230 240 250
TTGHICYHIT AQQGSGEGAV FTGDTLFQGG CGRFFEGTPE EMYEALCTKL
260 270 280 290 300
SALPDATKVF CGHEYTLQNM SFARHVEPDN EVIQQRIEWA KHRRASQDPT
310 320 330 340
VPSTIGEEKS WNPFMRVHEA TVQKHAGGAT DPVVTMGKLR KEKDTFKA
Length:348
Mass (Da):38,857
Last modified:March 1, 2003 - v1
Checksum:i632C20C6BDF1941A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014296 Genomic DNA Translation: AAN12145.1
RefSeqiNP_730568.1, NM_168873.2
UniGeneiDm.3633

Genome annotation databases

EnsemblMetazoaiFBtr0078254; FBpp0077912; FBgn0037024
GeneIDi40299
UCSCiCG4365-RC d. melanogaster

Similar proteinsi

Entry informationi

Entry nameiQ8IPU3_DROME
AccessioniPrimary (citable) accession number: Q8IPU3
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: June 20, 2018
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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