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Protein
Submitted name:

DNA repair helicase, putative

Gene

PF3D7_1408400

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Catalytic activityi

ATP + H2O = ADP + phosphate.SAAS annotation

GO - Molecular functioni

  • ATP binding Source: UniProtKB-KW
  • ATP-dependent DNA helicase activity Source: InterPro
  • DNA binding Source: InterPro
  • DNA helicase activity Source: GeneDB

GO - Biological processi

Keywordsi

Molecular functionHelicaseSAAS annotationImported, Hydrolase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
DNA repair helicase, putativeImported (EC:3.6.4.12Imported)
Gene namesi
ORF Names:PF3D7_1408400Imported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 14

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_1408400

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

NucleusSAAS annotation

Family & Domainsi

Phylogenomic databases

KOiK11136
OMAiFALEMQI

Family and domain databases

InterProiView protein in InterPro
IPR006555 ATP-dep_Helicase_C
IPR010614 DEAD_2
IPR014013 Helic_SF1/SF2_ATP-bd_DinG/Rad3
IPR006554 Helicase-like_DEXD_c2
IPR027417 P-loop_NTPase
IPR013020 Rad3/Chl1-like
PfamiView protein in Pfam
PF06733 DEAD_2, 1 hit
PF13307 Helicase_C_2, 1 hit
SMARTiView protein in SMART
SM00488 DEXDc2, 1 hit
SM00491 HELICc2, 1 hit
SUPFAMiSSF52540 SSF52540, 6 hits
TIGRFAMsiTIGR00604 rad3, 1 hit
PROSITEiView protein in PROSITE
PS51193 HELICASE_ATP_BIND_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q8IM12-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIEQKIHKRY KIVKKDDVNH RYTINDIEVY FPYELYDCQY NYMLSVLSAL
60 70 80 90 100
KKRENAILES PTGTGKTLCL LCASISYVVD ILEKKGHFNE NINISENNKN
110 120 130 140 150
ISLEFGKSNE SVPKKVVANE FPKIIYASRT HSQLKQVIKE LKNVYFIKNN
160 170 180 190 200
EKYKLLTTIL GSRDQLCVHN INYNYKGTLL NNMCKRTRKN GECIYHNGLK
210 220 230 240 250
YLYKLKHLFT TPMDVETLSE IGKGNSVGQN IHFCPFYATR EIQNECHIIL
260 270 280 290 300
LPYNYLFEES TRKILKLNLE NSIIIIDEGH NIENVAEEAV SFKLKDTDLN
310 320 330 340 350
LFLEALKATL TILEKVNEID KEIKDKINID ELFILNRSIN ALITWLHNLQ
360 370 380 390 400
LEKNEKKKIK EKHKIYQGKQ IFEIFEKNSI NITKDNFDNF NNLLTAMIEL
410 420 430 440 450
LNKYTNDFKL SQMDVKNINR FIASIDHVKK AFGILFSDIV KNCIEYFHLY
460 470 480 490 500
INEEKINNTD TFNNYNNNYG GSSNIDSMNF INSGKNYDGM NRFIKKKIAY
510 520 530 540 550
DNNVSNNNNT NYYDTFGSNN IYNNNTTNTF NNNTVCKNIS LLCFSATASL
560 570 580 590 600
CGIIKEKINS IIVTSGTLSP IEPFSKQLSG NYFSFKHILE NDHVIKSHQL
610 620 630 640 650
FVGCMTHYNN QILLSTYENR ANENYIRSLG NCIFDIIVCI PYGVLIFFSS
660 670 680 690 700
YSSMTETVNS WKKMKIYDKI NTYKTIFVEP NKATDLKDIL DQYEILIKKK
710 720 730 740 750
RKGAILMGVC RGKISEGIDF KDDCCRAVII CGLPYGNVYD SKIIFKKEFL
760 770 780 790 800
DNFKYQKTDE RPNSSNITSN ISKGNKWYNE EAMRSINQSI GRVIRHKNDY
810 820 830 840 850
GAIFFLDSRF SNNQRIKEIS KWVRTHFRIY RDVEQIQSDI DKFFELFKGL
860 870 880 890 900
NNPLQLQKDQ NINQKSNNTK IMNIYNDNIH DMNNSNTISE GGVTIKENNE
910 920 930 940 950
SIDNTNNNSS TKLIGKNFQD CFIKSDKNKK TNKHDMPQNK FSFNPTKKMK
960 970 980 990 1000
NQPKILSMIQ NITKGKNPEK KSIYIDNKNE NDIENQNNPN MNNNNNNNNI
1010 1020 1030 1040 1050
NTLNNKEESN VNNKCSSLKL DNAKLLIASF REILSKDIYD KFFELIKETK
1060 1070 1080 1090 1100
KKSNEKKYEI LINNILELIT QNFIRGNNEK KNINMSDEKQ KHILFNDIMN
1110 1120 1130 1140 1150
AQELIDIWKL LIKLINNFFP VQEKEKCFFI LQKRFKESTT DFDELEKYVY
1160
NYRLEKIEII
Length:1,160
Mass (Da):135,546
Last modified:March 1, 2003 - v1
Checksum:i239EEFE8A798AF43
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LN999946 Genomic DNA Translation: CZT99791.1
RefSeqiXP_001348254.1, XM_001348218.1

Genome annotation databases

EnsemblProtistsiCZT99791; CZT99791; PF3D7_1408400
GeneDBiPF3D7_1408400.1:pep
GeneIDi811663
KEGGipfa:PF3D7_1408400

Similar proteinsi

Entry informationi

Entry nameiQ8IM12_PLAF7
AccessioniPrimary (citable) accession number: Q8IM12
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: September 12, 2018
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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