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Protein
Submitted name:

Elongation factor 2

Gene

PF3D7_1451100

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionElongation factorImported
Biological processProtein biosynthesis

Enzyme and pathway databases

ReactomeiR-PFA-156902 Peptide chain elongation
R-PFA-5358493 Synthesis of diphthamide-EEF2
R-PFA-6798695 Neutrophil degranulation

Names & Taxonomyi

Protein namesi
Submitted name:
Elongation factor 2Imported
Gene namesi
ORF Names:PF3D7_1451100Imported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 14

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_1451100

Pathology & Biotechi

Chemistry databases

DrugBankiDB11638 Artenimol

PTM / Processingi

Proteomic databases

PRIDEiQ8IKW5

Interactioni

Protein-protein interaction databases

IntActiQ8IKW5, 1 interactor

Structurei

3D structure databases

SMRiQ8IKW5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

KOiK03234
OMAiEHLISGM

Family and domain databases

Gene3Di3.30.230.10, 2 hits
InterProiView protein in InterPro
IPR035647 EFG_III/V
IPR000640 EFG_V-like
IPR004161 EFTu-like_2
IPR031157 G_TR_CS
IPR027417 P-loop_NTPase
IPR020568 Ribosomal_S5_D2-typ_fold
IPR014721 Ribosomal_S5_D2-typ_fold_subgr
IPR005225 Small_GTP-bd_dom
IPR000795 TF_GTP-bd_dom
IPR009000 Transl_B-barrel_sf
IPR005517 Transl_elong_EFG/EF2_IV
PfamiView protein in Pfam
PF00679 EFG_C, 1 hit
PF03764 EFG_IV, 1 hit
PF00009 GTP_EFTU, 1 hit
PF03144 GTP_EFTU_D2, 1 hit
PRINTSiPR00315 ELONGATNFCT
SMARTiView protein in SMART
SM00838 EFG_C, 1 hit
SM00889 EFG_IV, 1 hit
SUPFAMiSSF50447 SSF50447, 1 hit
SSF52540 SSF52540, 1 hit
SSF54211 SSF54211, 1 hit
SSF54980 SSF54980, 2 hits
TIGRFAMsiTIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS00301 G_TR_1, 1 hit
PS51722 G_TR_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q8IKW5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVNFTVDQVR EIMNKTKQIR NMSVIAHVDH GKSTLTDSLV SKAGIISSKN
60 70 80 90 100
AGDARFTDTR QDEQERCITI KSTGISMYFE HDLEDGEGKK PFLINLIDSP
110 120 130 140 150
GHVDFSSEVT AALRVTDGAL VVVDTIEGVC VQTETVLYQA LGERIKPVLH
160 170 180 190 200
VNKVDRALLE LQMEVEDIYQ TFARTIESVN VIISTYTDKL MGDIQVYPEK
210 220 230 240 250
GTVSFGSGLQ GWAFTLETFS RIYSKKFGIE KKKMMQRLWG NSFYDAKTKK
260 270 280 290 300
WSKNQQEGYK RGFCQFIMEP ILNLCQSIMN DDKEKYTKML TNIGVELKGD
310 320 330 340 350
DKLLTGKQLL KKAMQLWLPA GDTLLEMIVT HLPSPADAQK YRVENLYEGP
360 370 380 390 400
MDDEAANAIR NCDPNGPLMM YISKMVPTSD KGRFYAFGRV FSGTVATGQK
410 420 430 440 450
VRIQGPHYVP GEKTDLYEKN IQRTVLMMGR YTEQVQDVPC GNTCCLVGVD
460 470 480 490 500
QYIVKSGTIT TFKEAHNIAD MKYSVSPVVR VAVKPKDSKQ LPKLVDGLKK
510 520 530 540 550
LAKSDPLVLC TTDESGEHII SGCGELHIEI CLKDLKDEYA QIDFIVSDPV
560 570 580 590 600
VSYRETVTEE STITCLGKSP NKHNRLFMKA YPLAEGLPEA IDKNKVSDKD
610 620 630 640 650
DPKTRANYLH SNFQWDKNLA LKIWAFGPET IGPNLLTDNT SGIQYMNEIK
660 670 680 690 700
VHCVAAFQWA SKEGVLCEEN MRGIEFRMLD VHMHADAIHR GAGQIMPACK
710 720 730 740 750
KCIYACELTA FPRLVEPIYL VDISCPQDVV SGVYGVLNKR RGIVISEEQK
760 770 780 790 800
LGTPLLKIQS HLPVSESFGF TSALRAATSG QAFPQCVFDH WSVLYDDPFD
810 820 830
SNKNSYKIIM NIRERKGIKV EMPQLDQYLD KL
Length:832
Mass (Da):93,523
Last modified:March 1, 2003 - v1
Checksum:i19CEDD2DD7EA82D4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LN999946 Genomic DNA Translation: CZU00206.1
RefSeqiXP_001348660.1, XM_001348624.1

Genome annotation databases

EnsemblProtistsiCZU00206; CZU00206; PF3D7_1451100
GeneDBiPF3D7_1451100.1:pep
GeneIDi812068
KEGGipfa:PF3D7_1451100

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LN999946 Genomic DNA Translation: CZU00206.1
RefSeqiXP_001348660.1, XM_001348624.1

3D structure databases

SMRiQ8IKW5
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ8IKW5, 1 interactor

Chemistry databases

DrugBankiDB11638 Artenimol

Proteomic databases

PRIDEiQ8IKW5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiCZU00206; CZU00206; PF3D7_1451100
GeneDBiPF3D7_1451100.1:pep
GeneIDi812068
KEGGipfa:PF3D7_1451100

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_1451100

Phylogenomic databases

KOiK03234
OMAiEHLISGM

Enzyme and pathway databases

ReactomeiR-PFA-156902 Peptide chain elongation
R-PFA-5358493 Synthesis of diphthamide-EEF2
R-PFA-6798695 Neutrophil degranulation

Family and domain databases

Gene3Di3.30.230.10, 2 hits
InterProiView protein in InterPro
IPR035647 EFG_III/V
IPR000640 EFG_V-like
IPR004161 EFTu-like_2
IPR031157 G_TR_CS
IPR027417 P-loop_NTPase
IPR020568 Ribosomal_S5_D2-typ_fold
IPR014721 Ribosomal_S5_D2-typ_fold_subgr
IPR005225 Small_GTP-bd_dom
IPR000795 TF_GTP-bd_dom
IPR009000 Transl_B-barrel_sf
IPR005517 Transl_elong_EFG/EF2_IV
PfamiView protein in Pfam
PF00679 EFG_C, 1 hit
PF03764 EFG_IV, 1 hit
PF00009 GTP_EFTU, 1 hit
PF03144 GTP_EFTU_D2, 1 hit
PRINTSiPR00315 ELONGATNFCT
SMARTiView protein in SMART
SM00838 EFG_C, 1 hit
SM00889 EFG_IV, 1 hit
SUPFAMiSSF50447 SSF50447, 1 hit
SSF52540 SSF52540, 1 hit
SSF54211 SSF54211, 1 hit
SSF54980 SSF54980, 2 hits
TIGRFAMsiTIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS00301 G_TR_1, 1 hit
PS51722 G_TR_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ8IKW5_PLAF7
AccessioniPrimary (citable) accession number: Q8IKW5
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: September 12, 2018
This is version 121 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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