UniProtKB - Q8IKV8 (Q8IKV8_PLAF7)
Protein
Submitted name:
Sortilin
Gene
PF3D7_1451800
Organism
Plasmodium falciparum (isolate 3D7)
Status
Functioni
GO - Molecular functioni
- lipid transporter activity Source: GeneDB
GO - Biological processi
- endocytosis Source: GeneDB
- post-Golgi vesicle-mediated transport Source: GO_Central
Names & Taxonomyi
Protein namesi | Submitted name: SortilinImported |
Gene namesi | ORF Names:PF3D7_1451800Imported |
Organismi | Plasmodium falciparum (isolate 3D7)Imported |
Taxonomic identifieri | 36329 [NCBI] |
Taxonomic lineagei | Eukaryota › Sar › Alveolata › Apicomplexa › Aconoidasida › Haemosporida › Plasmodiidae › Plasmodium › Plasmodium (Laverania) › |
Proteomesi |
|
Organism-specific databases
EuPathDBi | PlasmoDB:PF3D7_1451800 |
Subcellular locationi
GO - Cellular componenti
- Golgi apparatus Source: GeneDB
- integral component of membrane Source: GO_Central
Keywords - Cellular componenti
MembraneARBA annotationPTM / Processingi
Keywords - PTMi
GlycoproteinARBA annotationProteomic databases
PRIDEi | Q8IKV8 |
PTM databases
SwissPalmi | Q8IKV8 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 89 – 765 | VPS10InterPro annotationAdd BLAST | 677 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 840 – 863 | DisorderedSequence analysisAdd BLAST | 24 |
Sequence similaritiesi
Belongs to the VPS10-related sortilin family.ARBA annotation
Keywords - Domaini
RepeatARBA annotationPhylogenomic databases
HOGENOMi | CLU_013144_0_0_1 |
OMAi | FAPFYSV |
Family and domain databases
Gene3Di | 2.130.10.10, 1 hit |
InterProi | View protein in InterPro IPR036278, Sialidase_sf IPR031777, Sortilin_C IPR031778, Sortilin_N IPR006581, VPS10 IPR015943, WD40/YVTN_repeat-like_dom_sf |
Pfami | View protein in Pfam PF15902, Sortilin-Vps10, 1 hit PF15901, Sortilin_C, 1 hit |
SMARTi | View protein in SMART SM00602, VPS10, 1 hit |
SUPFAMi | SSF50939, SSF50939, 1 hit |
i Sequence
Sequence statusi: Complete.
Q8IKV8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKKKLEKQKK LLEYEKGYYS NKVKMRNMLF FKSIGNKNHL FLVFLLFLFF
60 70 80 90 100
SFSCINFTQC QITKKKVSVS EINFDSAVDD VQWCGNNHMT VLVKTVKGRL
110 120 130 140 150
YRSSDGGKIW TNITGNLSDK ENNKSDPSSN HMNEMTTVDL IMVNSVNKNI
160 170 180 190 200
VLIIGNQKNH YISEDSGETF RLLNYQNKIN FWQFHSTKTH WALVSSWTEA
210 220 230 240 250
CYSNDDNSGE CMQTLSLTKD LGRTFQLIDI YVVQFNWGDK ESHLEDTIYY
260 270 280 290 300
TRHKNRNGHQ QRFSGWSKDV DFVATHNFGK SVDVLVKQGN KFLISNGYIF
310 320 330 340 350
VAKLNDVIKQ TVNMMVSTDG GKTFNKANLP ENIHEKSYTV LDTSEGSIML
360 370 380 390 400
HVNHGTSSEK INTGNVYISD ASGLNYTLSL PNNIRTSSGE CEFDRVLSLD
410 420 430 440 450
GVYIANFLDV NNEIKDEDLR FQNFKSAIEE DIAPFETNTE KRKKQYNKGK
460 470 480 490 500
NEDAVRTVIS FNKGGEWSYL KAPKVDSRGN KYECGDNCYL HLHGITNYHQ
510 520 530 540 550
YAPFYSIENA VGIIMGTGNV GSHLRYESDE VNTFLSRDGG VTWIEAHKGP
560 570 580 590 600
YIYEYGDYGG LIVMADDLRK TNQIVFSWNE GQSWFDFELG QFSIDVDNIV
610 620 630 640 650
AEPNSASVEF LVYGTRNDVG VLYHLDFNAL GQPLCKGLWA ADSVSSDYET
660 670 680 690 700
WSPTSGNFND KCILGRKITY TRRKQTSECF NGKDLKRTVD KKPCECTPED
710 720 730 740 750
YECETGFTRK IGSYECKPND PTLTIEGCTS SSYFYANAYR KVPGDICVNG
760 770 780 790 800
WVPEKVPVPC PSYAPFNKTA KSILFIIFIM GIVMLIITYI CRNPKFKNLF
810 820 830 840 850
YNYGFDTFEN VKYSVIKTKR GNVNNNVFEP EMEFIDAEQD DNEEDVPTLL
860 870 880 890
PYSSDRNRST NKDFTLARNR TNQNNNITSR NISPSKNYAD NIELL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | LN999946 Genomic DNA Translation: CZU00213.1 |
RefSeqi | XP_001348667.1, XM_001348631.1 |
Genome annotation databases
EnsemblProtistsi | CZU00213; CZU00213; PF3D7_1451800 |
GeneDBi | PF3D7_1451800.1:pep |
GeneIDi | 812075 |
KEGGi | pfa:PF3D7_1451800 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | LN999946 Genomic DNA Translation: CZU00213.1 |
RefSeqi | XP_001348667.1, XM_001348631.1 |
3D structure databases
SMRi | Q8IKV8 |
ModBasei | Search... |
Protein-protein interaction databases
IntActi | Q8IKV8, 1 interactor |
PTM databases
SwissPalmi | Q8IKV8 |
Proteomic databases
PRIDEi | Q8IKV8 |
Genome annotation databases
EnsemblProtistsi | CZU00213; CZU00213; PF3D7_1451800 |
GeneDBi | PF3D7_1451800.1:pep |
GeneIDi | 812075 |
KEGGi | pfa:PF3D7_1451800 |
Organism-specific databases
EuPathDBi | PlasmoDB:PF3D7_1451800 |
Phylogenomic databases
HOGENOMi | CLU_013144_0_0_1 |
OMAi | FAPFYSV |
Family and domain databases
Gene3Di | 2.130.10.10, 1 hit |
InterProi | View protein in InterPro IPR036278, Sialidase_sf IPR031777, Sortilin_C IPR031778, Sortilin_N IPR006581, VPS10 IPR015943, WD40/YVTN_repeat-like_dom_sf |
Pfami | View protein in Pfam PF15902, Sortilin-Vps10, 1 hit PF15901, Sortilin_C, 1 hit |
SMARTi | View protein in SMART SM00602, VPS10, 1 hit |
SUPFAMi | SSF50939, SSF50939, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q8IKV8_PLAF7 | |
Accessioni | Q8IKV8Primary (citable) accession number: Q8IKV8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 1, 2003 |
Last sequence update: | March 1, 2003 | |
Last modified: | October 7, 2020 | |
This is version 109 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |