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Protein
Submitted name:

DNA polymerase alpha subunit B, putative

Gene

PF3D7_1463300

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

  • DNA binding Source: InterPro
  • DNA-directed DNA polymerase activity Source: GeneDB
  • protein heterodimerization activity Source: GO_Central

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-PFA-113501 Inhibition of replication initiation of damaged DNA by RB1/E2F1
R-PFA-174411 Polymerase switching on the C-strand of the telomere
R-PFA-174430 Telomere C-strand synthesis initiation
R-PFA-68952 DNA replication initiation
R-PFA-68962 Activation of the pre-replicative complex
R-PFA-69091 Polymerase switching
R-PFA-69166 Removal of the Flap Intermediate
R-PFA-69183 Processive synthesis on the lagging strand

Names & Taxonomyi

Protein namesi
Submitted name:
DNA polymerase alpha subunit B, putativeImported
Gene namesi
ORF Names:PF3D7_1463300Imported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 14

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_1463300

Subcellular locationi

GO - Cellular componenti

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiQ8IKK3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

KOiK02321
OMAiSYIYINE

Family and domain databases

InterProiView protein in InterPro
IPR007185 DNA_pol_alpha/epsilon_bsu
IPR016722 DNA_pol_alpha_bsu
PANTHERiPTHR23061 PTHR23061, 1 hit
PfamiView protein in Pfam
PF04042 DNA_pol_E_B, 1 hit
PIRSFiPIRSF018300 DNA_pol_alph_2, 2 hits

Sequencei

Sequence statusi: Complete.

Q8IKK3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKDIKQADVK HYLETYYTDN SIGDDLKEAF DYIERNKHKN NFHKLFEDYL
60 70 80 90 100
EDYNKKLLKN GTLLRDHVVY EYERVKQYNS ELIETEGRSC NNKYHYYINY
110 120 130 140 150
VNSINENYKF LGLDTNVICD CINKKISLFL ELFLKYSKKL NLNIEIEPIL
160 170 180 190 200
NMSDDESYIF GRIYTENEMN ISESNIILEG NMKWNNGDKA QLLNLTDMRN
210 220 230 240 250
ICFFLGQILA IKGKKEINQF SIKYYVSNVY AGLPSHLKVQ IDKEFVLKHF
260 270 280 290 300
NTKEIEEDSK IHENILHLYN NENIHIMICN GYIYNDNNYS ENLDNFLKVV
310 320 330 340 350
NEKLPHVVLI FGPFLYIRNF SETIQKIGDI NIIYENLFKK ITKFAKNEIL
360 370 380 390 400
EKTHFFIIPS IYDSINIYPL PQPPFYYENS NINSPNVHFL SNPSYIYINE
410 420 430 440 450
LKIALTSCDI VYNLTRNLLC RPSELKLFYL FEQILRQLSL FPSYPSEYNI
460 470 480 490 500
EITKFKNLLF QPNRLPDIFI YPSFTNEKSY IKEVHKKLFI CPYSIDVNKA
510 520 530
QPSKFFSNIY ILPPNETNEL SKRVILENIF ISNNKTNNI
Length:539
Mass (Da):64,036
Last modified:March 1, 2003 - v1
Checksum:i9858F3A28B08DEBD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LN999946 Genomic DNA Translation: CZU00330.1
RefSeqiXP_001348776.1, XM_001348740.1

Genome annotation databases

EnsemblProtistsiCZU00330; CZU00330; PF3D7_1463300
GeneDBiPF3D7_1463300.1:pep
GeneIDi812184
KEGGipfa:PF3D7_1463300

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LN999946 Genomic DNA Translation: CZU00330.1
RefSeqiXP_001348776.1, XM_001348740.1

3D structure databases

SMRiQ8IKK3
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiCZU00330; CZU00330; PF3D7_1463300
GeneDBiPF3D7_1463300.1:pep
GeneIDi812184
KEGGipfa:PF3D7_1463300

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_1463300

Phylogenomic databases

KOiK02321
OMAiSYIYINE

Enzyme and pathway databases

ReactomeiR-PFA-113501 Inhibition of replication initiation of damaged DNA by RB1/E2F1
R-PFA-174411 Polymerase switching on the C-strand of the telomere
R-PFA-174430 Telomere C-strand synthesis initiation
R-PFA-68952 DNA replication initiation
R-PFA-68962 Activation of the pre-replicative complex
R-PFA-69091 Polymerase switching
R-PFA-69166 Removal of the Flap Intermediate
R-PFA-69183 Processive synthesis on the lagging strand

Family and domain databases

InterProiView protein in InterPro
IPR007185 DNA_pol_alpha/epsilon_bsu
IPR016722 DNA_pol_alpha_bsu
PANTHERiPTHR23061 PTHR23061, 1 hit
PfamiView protein in Pfam
PF04042 DNA_pol_E_B, 1 hit
PIRSFiPIRSF018300 DNA_pol_alph_2, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiQ8IKK3_PLAF7
AccessioniPrimary (citable) accession number: Q8IKK3
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: September 12, 2018
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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