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Entry version 102 (05 Jun 2019)
Sequence version 1 (01 Mar 2003)
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Protein
Submitted name:

Uncharacterized protein

Gene

PF3D7_1021900

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
PLASMO:PF10_0213-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:PF3D7_1021900Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPlasmodium falciparum (isolate 3D7)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri36329 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001450 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
PlasmoDB:PF3D7_1021900

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q8IJI4

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q8IJI4, 3 interactors

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q8IJI4

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 158DisorderedSequence analysisAdd BLAST158
Regioni260 – 474DisorderedSequence analysisAdd BLAST215
Regioni517 – 637DisorderedSequence analysisAdd BLAST121
Regioni945 – 967DisorderedSequence analysisAdd BLAST23
Regioni991 – 1064DisorderedSequence analysisAdd BLAST74
Regioni1077 – 1155DisorderedSequence analysisAdd BLAST79
Regioni1296 – 1347DisorderedSequence analysisAdd BLAST52
Regioni1871 – 1980DisorderedSequence analysisAdd BLAST110

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili652 – 672Sequence analysisAdd BLAST21
Coiled coili1628 – 1655Sequence analysisAdd BLAST28
Coiled coili1662 – 1682Sequence analysisAdd BLAST21
Coiled coili1797 – 1820Sequence analysisAdd BLAST24
Coiled coili2016 – 2036Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 17PolyampholyteSequence analysisAdd BLAST17
Compositional biasi18 – 32PolarSequence analysisAdd BLAST15
Compositional biasi33 – 55PolyampholyteSequence analysisAdd BLAST23
Compositional biasi68 – 89PolyampholyteSequence analysisAdd BLAST22
Compositional biasi90 – 104PolarSequence analysisAdd BLAST15
Compositional biasi105 – 144PolyampholyteSequence analysisAdd BLAST40
Compositional biasi271 – 341PolarSequence analysisAdd BLAST71
Compositional biasi353 – 367PolyampholyteSequence analysisAdd BLAST15
Compositional biasi368 – 444PolarSequence analysisAdd BLAST77
Compositional biasi459 – 474PolarSequence analysisAdd BLAST16
Compositional biasi517 – 578PolarSequence analysisAdd BLAST62
Compositional biasi593 – 612PolarSequence analysisAdd BLAST20
Compositional biasi619 – 637PolarSequence analysisAdd BLAST19
Compositional biasi991 – 1018PolarSequence analysisAdd BLAST28
Compositional biasi1033 – 1064PolarSequence analysisAdd BLAST32
Compositional biasi1083 – 1104PolyampholyteSequence analysisAdd BLAST22
Compositional biasi1105 – 1153PolarSequence analysisAdd BLAST49
Compositional biasi1877 – 1948PolarSequence analysisAdd BLAST72
Compositional biasi1962 – 1980PolarSequence analysisAdd BLAST19

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

Identification of Orthologs from Complete Genome Data

More...
OMAi
YYDICEL

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00204 ANK, 2 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.10.1440, 1 hit
1.25.40.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR019385 PHAX_RNA-binding_domain
IPR038092 PHAX_RNA-binding_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12796 Ank_2, 2 hits
PF10258 RNA_GG_bind, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00248 ANK, 6 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48403 SSF48403, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q8IJI4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTLEKSLDQE KNKTEIENTG SKSIPNDSNE GANNKVDKND GNENVMKKNE
60 70 80 90 100
GDKNKVYNGT ADNNKVDNNK VDNNKVDNNK GDNNKVDNNK GDNNKVNNNK
110 120 130 140 150
GDNNKVDNNK VDNNKVDNNK VDNNKVDNNK GDNNKVDNNK GDNNKVDNNK
160 170 180 190 200
VNNNKVNNNK LVNNKVFNNK FNNNNIKNNR DNNKHTKNNR ADYHKVENTQ
210 220 230 240 250
IHISNKFQGN GKGYNMNYIN KKDANHEKGY KNNYENNRSL SYFYSKKNYN
260 270 280 290 300
EHFMPVNNVP FKKRGSDLYN NSKKESANDY TNDNQMNNNT KNNNQLNNNI
310 320 330 340 350
KNNNKLNNTT KNNNQSNNNT KNNTTKNNNQ INKNYNKNTK LNEQVEQREK
360 370 380 390 400
NANLSLKNNE EKQVENVKNI NKNNYSGSKN AWIKNEGTNN MNRTCKSGIH
410 420 430 440 450
NGNKNNNNNI NITNKDDNNN NNNNNNNNND NNNNNNNNNN NSENVNKKKN
460 470 480 490 500
KKKNKKKTNQ VSTNAWTNDK NSNLEHIIRN NQKKGTNPNT ENDHHNENAS
510 520 530 540 550
ITTAISINSN VTDTQTKKHM NYGSTNQKEQ KKRVQANSKV STNMKEDNKA
560 570 580 590 600
NIEITNFNNA NKSYSTNNNP SPNDNLNKGN VKNKKKSKKN KNNNNDSNNN
610 620 630 640 650
NDNNNNNIMN ENKKDINDNK IINNNNNNNN NNLNATKKNN TININNTIID
660 670 680 690 700
KNNNIENNFA FVNNLNENLE HNSMKLIGNN YPMNFENNEI KKKNITASKN
710 720 730 740 750
VPNKYNYDMI NQGNLNYMYN PLNYYNMNKY YDMPFIDNIA NNLNPMYFDN
760 770 780 790 800
DMQRNHMMEN IINYQGMYNM NNIYNTNNNM EQNTNNNNMY NHNSYANYKH
810 820 830 840 850
EHLSLNVYEG PLEKNNEWGK KKMNKKNNQS GMNQQNVMNQ QKVMNQPNAM
860 870 880 890 900
NFPNNMNHPN NMNHPNNMNH PNNMNHPNNM NHPNNMNHPN NMNHPNNMNH
910 920 930 940 950
LNNMNHPNNI NQPNLINYQY PMNHVQHINH PDNRNKMNNP NIPNYPNVNV
960 970 980 990 1000
SAPETKQDTK IIPNKEKKKI INNEGTVLQP LKNNVEHNKA NNLLTSKKHN
1010 1020 1030 1040 1050
TNVNNKKKSK NVQQETPIKH LPNEEENMKQ GKTKNSNNKN NNNKNNKNKN
1060 1070 1080 1090 1100
NNNNNNNNNL ESITKNKNNS QYISTNVENE NLNKNEQKGK MNKMKTKTQR
1110 1120 1130 1140 1150
FNKEEQNETN NFTNNNKKGS NRYQQNKKGQ FKNSNMNYNS WINNQQGNDQ
1160 1170 1180 1190 1200
QHLNTNVDKD KNKDFEVNHE IHKFIDYCLK NYGNRNIMDV LNEFSSSNGM
1210 1220 1230 1240 1250
NENFDELKNI FQIQLNEENF NALAALENEA QTNKFHFINE KNMNETIEKG
1260 1270 1280 1290 1300
IEEIFEDTNK DIIEEYDKFK KMLSESMDES SMRKIQIENK EISDNKEISD
1310 1320 1330 1340 1350
NKEISDNKEI SDNKKISDNK EINDNKEIND NEKINDNKKI NDNKDNNEKI
1360 1370 1380 1390 1400
EEKKELVENN TKNMFEENNK INITIPPGLS LPDINRALLH SAYLDNITVV
1410 1420 1430 1440 1450
KKCLEKKADI NYLDKIGRSA LHYACAGGYF DICELLIKNG AKVNVSDYKN
1460 1470 1480 1490 1500
WTPLHIAITK MHKDITELLL KNDANIHALL PHSLSPNRGK TTASMGIHFA
1510 1520 1530 1540 1550
AIKGNKEITK LLLQYGAKID DTDLSNRSAL HYAVYRNNCD YVKFLIYEEK
1560 1570 1580 1590 1600
ANVNILDIHN RLPIHSACLG GVLENVKILV ENKSYVHKKD IYNMSPLDIV
1610 1620 1630 1640 1650
QIKKFKDIKN YLTKCMNQNF SPISSDHLKK NDEEKENEIK NIDDFSNEKN
1660 1670 1680 1690 1700
EGEQKKKNMK NYENIKKENK DIMLNMDKQK TNDLEMFNDK FELNDEAKTM
1710 1720 1730 1740 1750
DPKEFYNDNQ MIKDMLTTTI STVLNERNKN QIKRVVDALG VYISLSLLEK
1760 1770 1780 1790 1800
TILIQNYGGI DMVNQKGKRS TGGVFFYLIK YMYKNDIISK FKYDYIIEEE
1810 1820 1830 1840 1850
KEKKKTYRKL KKKLLQDEEN FKNNETFVTK KNEENGCIED KCVDDDKEVK
1860 1870 1880 1890 1900
GNNVGTHTTL LRKGKKNFKF IDETKNKNKY SNNNNNNENK NNENKNNENN
1910 1920 1930 1940 1950
NNNKNNNNEN KKNNNKKNNN NNNNNNNNNN NKNNNINNNN NNNNNPQVHN
1960 1970 1980 1990 2000
KKNEKKSGCN IKTKEQNNNK NTNNMKKQNL KNEIRNNYQM IIEDEKKNFI
2010 2020 2030 2040 2050
KNDNKVLNYD KNLLQNNNCN MNIRNYNNSS QNYNNEYYNA SMANNNNYYY
2060 2070 2080 2090 2100
NSNQYNEHNY NHNNNYNDNN FNNNNYNLNN FNNNYNEFIS QNPGNAHMFN
2110 2120 2130 2140 2150
GQNNYIPIEQ LAVNIPTDDK SVKKKNKKKK NNKNSTQIII ENNKNNDTTY
2160 2170 2180 2190 2200
ISKDNVEPSF VNRMQDSYGN FHNVHDIAQQ KKHFYQMNTA PTTNSNNTNN
2210 2220 2230 2240 2250
NINGLENFKL NNNYNKEMMN YQNNVMSSYL NNTRNNAYDY MLRSKNNFPN
2260 2270 2280 2290
YMNNPNMSML NDLNKYYGNN NQKFPLNNME YMYYNNYSKL
Length:2,290
Mass (Da):267,386
Last modified:March 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF0FA725912B78496
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
LN999944 Genomic DNA Translation: CZT98474.1

NCBI Reference Sequences

More...
RefSeqi
XP_001347497.1, XM_001347461.1

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
CZT98474; CZT98474; PF3D7_1021900

GeneDB pathogen genome database from Sanger Institute

More...
GeneDBi
PF3D7_1021900.1:pep

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
810370

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
pfa:PF3D7_1021900

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LN999944 Genomic DNA Translation: CZT98474.1
RefSeqiXP_001347497.1, XM_001347461.1

3D structure databases

SMRiQ8IJI4
ModBaseiSearch...

Protein-protein interaction databases

IntActiQ8IJI4, 3 interactors

Proteomic databases

PRIDEiQ8IJI4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiCZT98474; CZT98474; PF3D7_1021900
GeneDBiPF3D7_1021900.1:pep
GeneIDi810370
KEGGipfa:PF3D7_1021900

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_1021900

Phylogenomic databases

OMAiYYDICEL

Enzyme and pathway databases

BioCyciPLASMO:PF10_0213-MONOMER

Family and domain databases

CDDicd00204 ANK, 2 hits
Gene3Di1.10.10.1440, 1 hit
1.25.40.20, 1 hit
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR019385 PHAX_RNA-binding_domain
IPR038092 PHAX_RNA-binding_sf
PfamiView protein in Pfam
PF12796 Ank_2, 2 hits
PF10258 RNA_GG_bind, 1 hit
SMARTiView protein in SMART
SM00248 ANK, 6 hits
SUPFAMiSSF48403 SSF48403, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ8IJI4_PLAF7
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8IJI4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: June 5, 2019
This is version 102 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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