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Entry version 125 (19 Jan 2022)
Sequence version 1 (01 Mar 2003)
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Protein
Submitted name:

Dynein heavy chain, putative

Gene

PF3D7_1023100

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionMotor proteinARBA annotation
LigandATP-bindingARBA annotation, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Dynein heavy chain, putativeImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:PF3D7_1023100Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPlasmodium falciparum (isolate 3D7)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri36329 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaSarAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001450 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
PlasmoDB:PF3D7_1023100

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, CytoskeletonARBA annotation, DyneinARBA annotation, MicrotubuleARBA annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q8IJH4

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
5833.PF10_0224

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8IJH4

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1753 – 2012DHC_N2InterPro annotationAdd BLAST260
Domaini2321 – 2620AAA_6InterPro annotationAdd BLAST300
Domaini2728 – 2805AAA_6InterPro annotationAdd BLAST78
Domaini3802 – 4060AAA_8InterPro annotationAdd BLAST259
Domaini4073 – 4411MTInterPro annotationAdd BLAST339
Domaini4437 – 4546AAA_9InterPro annotationAdd BLAST110
Domaini4651 – 4759AAA_9InterPro annotationAdd BLAST109
Domaini5087 – 5202Dynein_heavyInterPro annotationAdd BLAST116
Domaini5233 – 5374AAA_lid_11InterPro annotationAdd BLAST142
Domaini5380 – 5682Dynein_CInterPro annotationAdd BLAST303

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni2005 – 2115DisorderedSequence analysisAdd BLAST111
Regioni3033 – 3062DisorderedSequence analysisAdd BLAST30
Regioni3239 – 3261DisorderedSequence analysisAdd BLAST23
Regioni3678 – 3698DisorderedSequence analysisAdd BLAST21
Regioni4573 – 4633DisorderedSequence analysisAdd BLAST61
Regioni4840 – 4863DisorderedSequence analysisAdd BLAST24
Regioni4875 – 4898DisorderedSequence analysisAdd BLAST24

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili249 – 269Sequence analysisAdd BLAST21
Coiled coili438 – 458Sequence analysisAdd BLAST21
Coiled coili1400 – 1423Sequence analysisAdd BLAST24
Coiled coili1464 – 1520Sequence analysisAdd BLAST57
Coiled coili3212 – 3232Sequence analysisAdd BLAST21
Coiled coili3304 – 3324Sequence analysisAdd BLAST21
Coiled coili4086 – 4123Sequence analysisAdd BLAST38
Coiled coili4284 – 4367Sequence analysisAdd BLAST84
Coiled coili4706 – 4726Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi2013 – 2092Basic and acidic residuesSequence analysisAdd BLAST80
Compositional biasi3678 – 3694Polar residuesSequence analysisAdd BLAST17
Compositional biasi4876 – 4898Polar residuesSequence analysisAdd BLAST23

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the dynein heavy chain family.ARBA annotation

Keywords - Domaini

Coiled coilSequence analysisARBA annotation

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000038_4_0_1

Identification of Orthologs from Complete Genome Data

More...
OMAi
CAYLALW

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8IJH4

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.8.710, 1 hit
1.10.8.720, 1 hit
1.20.140.100, 1 hit
3.10.490.20, 1 hit
3.20.180.20, 1 hit
3.40.50.300, 6 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR035699, AAA_6
IPR035706, AAA_9
IPR041658, AAA_lid_11
IPR042219, AAA_lid_11_sf
IPR026983, DHC_fam
IPR042222, Dynein_2_N
IPR043157, Dynein_AAA1S
IPR041228, Dynein_C
IPR043160, Dynein_C_barrel
IPR024743, Dynein_HC_stalk
IPR024317, Dynein_heavy_chain_D4_dom
IPR004273, Dynein_heavy_D6_P-loop
IPR013602, Dynein_heavy_linker
IPR042228, Dynein_linker_3
IPR027417, P-loop_NTPase

The PANTHER Classification System

More...
PANTHERi
PTHR10676, PTHR10676, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12774, AAA_6, 2 hits
PF12780, AAA_8, 1 hit
PF12781, AAA_9, 2 hits
PF18198, AAA_lid_11, 1 hit
PF08393, DHC_N2, 1 hit
PF18199, Dynein_C, 1 hit
PF03028, Dynein_heavy, 1 hit
PF12777, MT, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540, SSF52540, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q8IJH4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSKKNDVYEE NGEYNPKVEE LLTSALEFFN IHGLAREEVI NNIKKDENTI
60 70 80 90 100
KLLNDFYEKN EECLFIFNEK DCIKIYNSIL DLYKKRKNEK FLIIYKTPQS
110 120 130 140 150
NILYLEMNND AENVIRNFLE IFFSNFMNKN EDINSSSLLK EMKKKFNNFL
160 170 180 190 200
LNLRIIYGET EEKLTLPYAP SEIKEENVNT IEEYLIHFIK CYHIILRNFM
210 220 230 240 250
NYKKKEYINC YEFLKCLKNK SEDINYLYNE IDKESFQEII NIILEKKKNS
260 270 280 290 300
SYKNIIENIK KEISEHKMEI LDLYTHLKPV VHFLQKLEFN KDDDIEKKYI
310 320 330 340 350
YITPIIHSLS ISIDKSNYLI KNCKFVFNFL SKVLINSCNQ NLNTPEIINS
360 370 380 390 400
IYNCVDVLKI KLYDTLNFLL NFLYIFKMYK SKNEKLQSLH EHNTYVIQRK
410 420 430 440 450
TQIQVTSEKG NELDINMSPE KKKNNNINID IISSYQNGNN NEENLNQEDD
460 470 480 490 500
IKNELEEEYS YFPSISLYMY KLKILIEYLK IYQTYMKLEK IEIPGEKGKN
510 520 530 540 550
LTEEIHNISN DFNIINENFL DINHEILNEH EHIFINKYNI FESRVKELNK
560 570 580 590 600
RLICVFVYSF DNDLKKNIKL LNSFLILRDI HVIEVELIRH ASLLCQDLKK
610 620 630 640 650
EFILVDNLFI KNKTIIENNK KMFLEDKFQQ GQCDLDGIKN VMSNNIEEEH
660 670 680 690 700
INKKNITGEN IISNNIEEEH INKKNITGEN IISNNIQDDN TANTNIADET
710 720 730 740 750
IPDVKAPSIT NNINVNINVN INVNINVNNK MKDKLEIDKM EREIKERFED
760 770 780 790 800
NLKRLNINKN SPLFCEVINL FTSLLKRIEQ QYFPLKKIIK VLKFENEKTE
810 820 830 840 850
EVKHLYKNIN EKISKYINDV SKEWFKETID VVNNFLNEYI FKKRNDLFYV
860 870 880 890 900
NFHPYIFMFI NNIKNFFLNN LSVNEDCLHI YNKANTFKKF INILNNITKK
910 920 930 940 950
YNSVLTKTLD VEKELFEEKM NNIKNRLLKG VKELKWSDDN IYEYIESVDK
960 970 980 990 1000
DMSDIYNNIS TLHNNIVSIL NVTSNWVKKS IIEKRKRNED IYTYLNNYKN
1010 1020 1030 1040 1050
NMSILKGKLN DDFKNINMNI KQSYDILKIK KNNIMWKNYL KFLNNIIIDK
1060 1070 1080 1090 1100
LIHLTNFLFN NLYDVMKCTK RDEQLFIIRI NFIENKLNLD LKLTSKKTFC
1110 1120 1130 1140 1150
IETIFYKWID DFMNLCSGIR RIDIKSGDYL NEILLSLSIH YNKNKIENFF
1160 1170 1180 1190 1200
QSTIKKSYEY LHSLTKYEHI WKIDIKKEFL SFKKKNEIQL YPTYFEYNNN
1210 1220 1230 1240 1250
FQDSLKLINI NIPYLFPNVL AYKKLILTLK QDLNKFYHLK TYEPINFILF
1260 1270 1280 1290 1300
YSENFVEKLI NFTKKNISLY SEYLQNFVKD VVYSINSFYE NVINNLKEIS
1310 1320 1330 1340 1350
IVDFFSKKGD SKKEILEKGE TNTGLQKGEK NVRLKKESID NMDISKMDNN
1360 1370 1380 1390 1400
NNQMNDDNNQ MNDFDDNDKM IDLDDNDKMI DFDDDDNNNI YDESKRYKNK
1410 1420 1430 1440 1450
NALKNEVEEK EKEKTNVSNI NKKKDIFYNL MRNLRSVKLS RKIIPLIFQK
1460 1470 1480 1490 1500
IKEIMENLKE LDIIIKYNDI LDNIEKNKEK VEIQYNDIKE KILKYKNNEI
1510 1520 1530 1540 1550
KNIKLEIKDF KEELTKLKKH IFKNIPSTPK DIYNFPYEKI NEFRKSFQTY
1560 1570 1580 1590 1600
KDKQKYHNEL EILFEIDITI FDELDQIDIK LTDLKHLWDL VNSIIFFIEQ
1610 1620 1630 1640 1650
EKKKLWKNID VNSNIYLIDF ISLYIRKNFF DLKHLSIYEY IIKELKKLSS
1660 1670 1680 1690 1700
ILPLLVDLNN ECIFDRHWNI IINISGNINN LYTKKKENNN NNNNNQNNYI
1710 1720 1730 1740 1750
NNTDLLNTPL SNNNKTSIMS IHTFNKEEQI NNDNTYDNEK ETNNNIFLNK
1760 1770 1780 1790 1800
NIQIKYKELT LQGFFDLKLY KHVDAVHDVI EQAKKEQKIE NKIKEINVIW
1810 1820 1830 1840 1850
KEMNFEFFKK NNYIQITNMD MILEIVDVHT SEILFFINQK KFILFIQETI
1860 1870 1880 1890 1900
LNTQENLKKI DEVINIWRKF LNKFERLQPI YLNSEDIHSQ LPEESKMFFN
1910 1920 1930 1940 1950
IENEYKEIIH SAAEQKNVLQ VCLNEDLFYL LSKFFKNIEL CEKALNDYLD
1960 1970 1980 1990 2000
QKKKAFPRFY FLSNIALLDI LSNGKNPFKI LPYINDVFNA IKTIQFKEDL
2010 2020 2030 2040 2050
VQRGPVSELN EQNEENDLVK NEERSETQKD QKDQKDQKDQ KDQKDQKDQK
2060 2070 2080 2090 2100
DQKDQKDQKD QKDQKDQKDQ KDQKDQKDQK NVNTDGKMDG YTDDKMNGYT
2110 2120 2130 2140 2150
NDASYYGQEE DETYEGENKK CKDIKTCESK DYIAKGVYSV ENEHLEFLNE
2160 2170 2180 2190 2200
LVLKGNVENY LKDLETHLKV TIRSILENAK ICSENLDEQN RDETMITNYI
2210 2220 2230 2240 2250
SQVVCTCNQI IVTEEINKCF DELENGNESA FVDYKKVLIE RINKLIKLVE
2260 2270 2280 2290 2300
KTDDYNIRTK LLSLIILDVH TRDVIISFIK KKISDSTSFD WQAQLKYYWV
2310 2320 2330 2340 2350
YDKKINNYTC EIKLCDFKTK YLYEYIGNSG KLVITPLTDK CYITLTQALN
2360 2370 2380 2390 2400
LILGGAPAGP AGTGKTETTK DLSKAIGIAI FIFNCSNQMN YFNMSQICIG
2410 2420 2430 2440 2450
LSQTGAWGCF DEFNRISIEV LSVVSTQIKC IFDAIKEKKT MFHFIDDEIV
2460 2470 2480 2490 2500
LKKTCGFFIT MNPGYAGRTE LPENLKNLFR SCSMIVPDIK FICENMLMSF
2510 2520 2530 2540 2550
GFIKANKLSY KFVELYQLCK ELLQKNIHYD WGLRAVKVVL IQAGNLKRKY
2560 2570 2580 2590 2600
ANFDEEIILM KALKDFNIPK ITYEDIPIFL GLINDLFPNV NCNIFDEKDQ
2610 2620 2630 2640 2650
EKENDYDEEH KQEQQTYIIQ DEEKKLYKKK KNIHHNIDKY KSSITQNFTN
2660 2670 2680 2690 2700
ANDNKNHLSI NKDNYETNKN LLTHYQHDIC EDISQIDKTK KDVQIYDEAH
2710 2720 2730 2740 2750
NEKSDINELN QKTNIIANQN VNENYINNKE YDKDSNKIDN LKQNKFMNEE
2760 2770 2780 2790 2800
KRIIIHNFDD AIKICLKESN LQIDDNFILK VKQLKDLMDV RHCVFILGED
2810 2820 2830 2840 2850
GCGKSSVIDI LIKSLNKINE KCLYEIINPK SIESYELYGY LTKNNEWIDG
2860 2870 2880 2890 2900
ALSSIMRKMS RNISPYNENI KHKITLLDGN IDAEWIESMN TVMDDNKVLT
2910 2920 2930 2940 2950
LVSNERIPFT KEMHLFFEIT NMKYASPATV SRGGVLFINK GDISYKLFIS
2960 2970 2980 2990 3000
SWINLLNNNI AKTEFYYLFN IFYSQNIDML RKQCKFAFDL SNLDIVKSIC
3010 3020 3030 3040 3050
NYIDYFLYKY EKYINEVIKK IENKQNEEIT FMKNENNRED LSNSNMKRKD
3060 3070 3080 3090 3100
KTTKDKDTKE INDIHNKDIK THEKGSQKMD KKTNSFKDKI ITNDNESKLK
3110 3120 3130 3140 3150
HQKNMNHVDD IKMNTKNLIN NEEKNIINKI NYNYEILKDY YNCFFMNSYM
3160 3170 3180 3190 3200
WVINNLIIDD KIMNSKNIFS NNIKSNLKVK MGNDYCCNYI YNIYENNWKH
3210 3220 3230 3240 3250
LSEYLDEDIL FLQKLKWKTS EMENEEKGYE HEVVLEGDED DNMDDANENM
3260 3270 3280 3290 3300
DDANENMDDT NENMDETNEN MDETNENMDD TNENVDDIHD NMDDTHDNMD
3310 3320 3330 3340 3350
EKKKKKLIKN KKKKKKAINN YIENMLPNNY DDIYINTIEL IRIEKMIKYC
3360 3370 3380 3390 3400
LERNQAILVY GNNGTGKTKC IKNNINMNIE KFTHTIISIN YYTNSFVLQK
3410 3420 3430 3440 3450
IIENNVEKRN TRTYGPPNQK KHIFFLEDLN ITAKDNCDTQ QTLEFLRQLL
3460 3470 3480 3490 3500
TYKLIYDRDN LDEKKFIHDI SFIGTINNNT NKLIDKRIQN KFSIINIDDI
3510 3520 3530 3540 3550
SMKTFENIYK IILKQHLLKF DDSIKCLLNN IISFSYDLYT NITENISFNL
3560 3570 3580 3590 3600
SNLAPHYLFN LNDIHTIFYN IIKCTNPDIY NNQFKFLMIV FHEMQHAYIN
3610 3620 3630 3640 3650
KLISDDHINI FTQLFNKLVQ QYFPFFKEDF EKHIDMFDST NEPHNVEHGQ
3660 3670 3680 3690 3700
DITSNKSLTF HENDNVDDDT YNNNMDNGFK NDRNVNNNNI DGDDNGDGIN
3710 3720 3730 3740 3750
VRTVEKTHLD MSNNLNNSND KDNIMKMKKS NNINTDSYNN NNINVKVKEK
3760 3770 3780 3790 3800
NLIYDLNKNI FTSFISIRNG LDKMYLNVKK FYVLKEVLTE KLNEYNTTHV
3810 3820 3830 3840 3850
ELPLVLFDYA IIQICKICRI LDFNISHLML IGFGGSGKQS LIKLSIFINS
3860 3870 3880 3890 3900
LNLLNISTNN NYDVNNFKSD LQEFHLKCAI KPGNVHVLLL KENDILDSFL
3910 3920 3930 3940 3950
PYINDLTSTG LCNDLFTKDE YLGIFSSIRN QIKYLNIGES NEDVFNYYIN
3960 3970 3980 3990 4000
KIKTNFKIAI THSPISNLYR DRLIKFPSFL SNFSFIYFLP WPYEALVNVS
4010 4020 4030 4040 4050
NKFLSDIKIK QDLKKKICEH MAYVHTSTNE MNKKYLEQKI RYNYVIPKTF
4060 4070 4080 4090 4100
LEYIYFYKNL LNVKNFEIEK SVERLNKGLL ALTSTRENVQ LLQKEIEIKI
4110 4120 4130 4140 4150
TNIEEKKIEV NEILNKVKEA TEVTNKEQQI VNEEKKKTEI FTKEAIEIQL
4160 4170 4180 4190 4200
KADKELSEAL PIMNKAKDAV NCITKSAIQE LKSLQNPPKE CLDVTHAVLI
4210 4220 4230 4240 4250
ALKEIKNYSW KFAQKIMNNP TQFLSKLQKF DAENMDEETV NLLTPFIQKK
4260 4270 4280 4290 4300
FFNYEMMKTK SSACAYLALW LVNIVKYNEV YKKVKPLMDK LQEATNNKNK
4310 4320 4330 4340 4350
AQEKLDQLEN KVKELTDSVE KLRRKMNEVN EEKNNVIKIY NESKDKLNRA
4360 4370 4380 4390 4400
ENLVNMLSDE YSRWSDEIAI INSNKKFIYG DCLLLSSFIT YLGVFSSSFR
4410 4420 4430 4440 4450
IKLWKHLWLE HIKNSNILIN NITSPIDIMV QDIQIATWKN EKLPEDIISI
4460 4470 4480 4490 4500
ENALIVSTCY RWPLLIDPQL QGLKWLKAKG GNNITVLQFN CDHFIKKIKN
4510 4520 4530 4540 4550
VISKGGYLII ENISEEIDNV IDGLLNREFI KKGNDIYIKI DNEEMLFNYP
4560 4570 4580 4590 4600
NAINRIDKIK SFFETNINSN TATTTTTTTN NNNNNNNNDN ITINNSGASQ
4610 4620 4630 4640 4650
INNTNNDNNN ITIDNQNNYG NEPGDSNKNY HKQNSQNMNK AFSSENLYKV
4660 4670 4680 4690 4700
NFFNLILQTK LSNPHFKPEV NSQCTLINFS VTCEGLEEQI LAIIVNIEKP
4710 4720 4730 4740 4750
ELEKQKQILV KNRNEYKIIL NNLEDEILYQ LSTVDSKTII DNISLINSLK
4760 4770 4780 4790 4800
TTKDTSINIQ KQVADSINTE NEINKTRELY RTLANEASIV YFILILMHNI
4810 4820 4830 4840 4850
NYMYQYSLDS FINLLLKSIE VVNSDSMKML SNKNLDSQIS NNNHMYDDDD
4860 4870 4880 4890 4900
NNNNNNGEHR HLQKHDDKYY DSKIYLNDND ENNNNNNDDN NNNNNNINNV
4910 4920 4930 4940 4950
YDEHMNKLII SFRKTIYSWI NRGLLEKDKL LFNCIFVFKL LEKKKIYDKD
4960 4970 4980 4990 5000
FNMDYLNFFL KPPRGKGVTE NPLKEWLSDD CWENILILSK FKEFENLSNN
5010 5020 5030 5040 5050
IHIDAQHKFK QWCSEIQPEI CKLPLEWKKL NNYSFKKLLI IRSLRPDRIT
5060 5070 5080 5090 5100
VTLEKYIKSI LPNSEEIMEK KNSFVDTLES SYNFMVNSTP ILFILTPGSD
5110 5120 5130 5140 5150
FIKYVEILGK KYKFYLNQNL HVVSLGQGQE SIALSKLELS HKEGHWIVLE
5160 5170 5180 5190 5200
NIHLMAKFNL ILENVIDKYA TEGSHPNFRC FLTSEITTNI PISILERSIK
5210 5220 5230 5240 5250
LTNEAPTGFK ENLKRAFTFF SPDDYEEKDL RTKNILFSLC YFHSIIVERA
5260 5270 5280 5290 5300
KFGSQGFNIK YPFSLSDLRD SAKVLFNYLD NQNSIKVPWN DLKYIFGEIM
5310 5320 5330 5340 5350
YGGHIVNDKD MLICKTYLNY FMKEQSLEGM QLIPFSKNIQ LFSPNNYSYE
5360 5370 5380 5390 5400
KILKYIDTQI IFESSILYGL NQHAEMNFRT NESIKLLKNI LKLKLKETST
5410 5420 5430 5440 5450
FVEELTTGET KENKTSNILS EILSEIDNIF FNVEELMKSI PDDQITPLQY
5460 5470 5480 5490 5500
FLFQECTLMN SLTSVMKNSL KELNLAIKGE INMTSKIESL MNALYKDKLP
5510 5520 5530 5540 5550
ELWKNNSYSS NRNLSSWVNN LKERIAFLTE WFNDPLLTPK VFNISLLFNP
5560 5570 5580 5590 5600
NSFFSAIKQI LSRNEKCELD KIIMQIEVTN KSLNNIHSYP KEGAYIYGLY
5610 5620 5630 5640 5650
LDGANYDVEK NTLCDSSSKQ KYFLMPVIHC KPIVSMGKID TDVYECPVYK
5660 5670 5680
TLSRGPTYVT NIKLKTKESS EKWILAGVAL ILDIADD
Length:5,687
Mass (Da):671,876
Last modified:March 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i136DFADD127DC99D
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
LN999944 Genomic DNA Translation: CZT98486.1

NCBI Reference Sequences

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RefSeqi
XP_001347508.1, XM_001347472.1

Genome annotation databases

Ensembl protists genome annotation project

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EnsemblProtistsi
CZT98486; CZT98486; PF3D7_1023100

Database of genes from NCBI RefSeq genomes

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GeneIDi
810381

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
pfa:PF3D7_1023100

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LN999944 Genomic DNA Translation: CZT98486.1
RefSeqiXP_001347508.1, XM_001347472.1

3D structure databases

SMRiQ8IJH4
ModBaseiSearch...

Protein-protein interaction databases

STRINGi5833.PF10_0224

Proteomic databases

PRIDEiQ8IJH4

Genome annotation databases

EnsemblProtistsiCZT98486; CZT98486; PF3D7_1023100
GeneIDi810381
KEGGipfa:PF3D7_1023100

Organism-specific databases

VEuPathDBiPlasmoDB:PF3D7_1023100

Phylogenomic databases

HOGENOMiCLU_000038_4_0_1
OMAiCAYLALW
PhylomeDBiQ8IJH4

Family and domain databases

Gene3Di1.10.8.710, 1 hit
1.10.8.720, 1 hit
1.20.140.100, 1 hit
3.10.490.20, 1 hit
3.20.180.20, 1 hit
3.40.50.300, 6 hits
InterProiView protein in InterPro
IPR035699, AAA_6
IPR035706, AAA_9
IPR041658, AAA_lid_11
IPR042219, AAA_lid_11_sf
IPR026983, DHC_fam
IPR042222, Dynein_2_N
IPR043157, Dynein_AAA1S
IPR041228, Dynein_C
IPR043160, Dynein_C_barrel
IPR024743, Dynein_HC_stalk
IPR024317, Dynein_heavy_chain_D4_dom
IPR004273, Dynein_heavy_D6_P-loop
IPR013602, Dynein_heavy_linker
IPR042228, Dynein_linker_3
IPR027417, P-loop_NTPase
PANTHERiPTHR10676, PTHR10676, 1 hit
PfamiView protein in Pfam
PF12774, AAA_6, 2 hits
PF12780, AAA_8, 1 hit
PF12781, AAA_9, 2 hits
PF18198, AAA_lid_11, 1 hit
PF08393, DHC_N2, 1 hit
PF18199, Dynein_C, 1 hit
PF03028, Dynein_heavy, 1 hit
PF12777, MT, 1 hit
SUPFAMiSSF52540, SSF52540, 4 hits

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ8IJH4_PLAF7
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8IJH4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: January 19, 2022
This is version 125 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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