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UniProtKB - Q8II79 (Q8II79_PLAF7)
Protein
Submitted name:
Bifunctional farnesyl/geranylgeranyl diphosphate synthase
Gene
PF3D7_1128400
Organism
Plasmodium falciparum (isolate 3D7)
Status
Functioni
Cofactori
Mg2+ARBA annotation
GO - Molecular functioni
- dimethylallyltranstransferase activity Source: GO_Central
- farnesyltranstransferase activity Source: UniProtKB-EC
- geranyltranstransferase activity Source: GeneDB
GO - Biological processi
- farnesyl diphosphate biosynthetic process Source: GO_Central
- isoprenoid biosynthetic process Source: GeneDB
Keywordsi
Molecular function | TransferaseUniRule annotationImported |
Ligand | MagnesiumARBA annotation |
Enzyme and pathway databases
BRENDAi | 2.5.1.29, 4889 |
Reactomei | R-PFA-191273, Cholesterol biosynthesis |
Names & Taxonomyi
Protein namesi | Submitted name: Bifunctional farnesyl/geranylgeranyl diphosphate synthaseImported (EC:2.5.1.29Imported) |
Gene namesi | ORF Names:PF3D7_1128400Imported |
Organismi | Plasmodium falciparum (isolate 3D7)Imported |
Taxonomic identifieri | 36329 [NCBI] |
Taxonomic lineagei | Eukaryota › Sar › Alveolata › Apicomplexa › Aconoidasida › Haemosporida › Plasmodiidae › Plasmodium › Plasmodium (Laverania) › |
Proteomesi |
|
Organism-specific databases
VEuPathDBi | PlasmoDB:PF3D7_1128400 |
Family & Domainsi
Sequence similaritiesi
Belongs to the FPP/GGPP synthase family.UniRule annotation
Phylogenomic databases
HOGENOMi | CLU_028376_0_1_1 |
OMAi | FHETTFQ |
PhylomeDBi | Q8II79 |
Family and domain databases
CDDi | cd00685, Trans_IPPS_HT, 1 hit |
Gene3Di | 1.10.600.10, 1 hit |
InterProi | View protein in InterPro IPR039702, FPS1-like IPR008949, Isoprenoid_synthase_dom_sf IPR000092, Polyprenyl_synt IPR033749, Polyprenyl_synt_CS |
PANTHERi | PTHR11525, PTHR11525, 1 hit |
Pfami | View protein in Pfam PF00348, polyprenyl_synt, 1 hit |
SUPFAMi | SSF48576, SSF48576, 1 hit |
PROSITEi | View protein in PROSITE PS00444, POLYPRENYL_SYNTHASE_2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q8II79-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MENEQNNQDS ENGLDYFRSM YDRYRDVFIN HINDYVLEDD IKIIISKYYK
60 70 80 90 100
LLFDYNCLGG KNNRGILVIL IYEYVKNRDI NCNEWEKVAC IAWCIEILQA
110 120 130 140 150
SFLVADDIMD KGETRRNKHC WYLLKDVEIK NAVNDVFLLY NAIYKLLDVY
160 170 180 190 200
LRNDNCYLDL ITSFREATLK TIVGQHLDTN IFSDKYSHID KDIDVNNINI
210 220 230 240 250
SQENKININM LNFKVYQNII IHKTAYYSFF LPIVCGMQMG GISLDNLLYK
260 270 280 290 300
KVENIAILMG EYFQVHDDYI DTFGDSKKTG KVGSDIQNNK LTWPLIKAFE
310 320 330 340 350
LCSQPEKEDI IRNYGKDNVT CIKFINDIYE HYNIRDHYVE YEKKQKMKIL
360 370
EAINQLHHEG IEYVLKYVMD ILFTGA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | LN999945 Genomic DNA Translation: CZT98947.1 |
RefSeqi | XP_001347966.2, XM_001347930.2 |
Genome annotation databases
EnsemblProtistsi | CZT98947; CZT98947; PF3D7_1128400 |
GeneIDi | 810842 |
KEGGi | pfa:PF3D7_1128400 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | LN999945 Genomic DNA Translation: CZT98947.1 |
RefSeqi | XP_001347966.2, XM_001347930.2 |
3D structure databases
SMRi | Q8II79 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 5833.PF11_0295 |
Proteomic databases
PRIDEi | Q8II79 |
Genome annotation databases
EnsemblProtistsi | CZT98947; CZT98947; PF3D7_1128400 |
GeneIDi | 810842 |
KEGGi | pfa:PF3D7_1128400 |
Organism-specific databases
VEuPathDBi | PlasmoDB:PF3D7_1128400 |
Phylogenomic databases
HOGENOMi | CLU_028376_0_1_1 |
OMAi | FHETTFQ |
PhylomeDBi | Q8II79 |
Enzyme and pathway databases
BRENDAi | 2.5.1.29, 4889 |
Reactomei | R-PFA-191273, Cholesterol biosynthesis |
Family and domain databases
CDDi | cd00685, Trans_IPPS_HT, 1 hit |
Gene3Di | 1.10.600.10, 1 hit |
InterProi | View protein in InterPro IPR039702, FPS1-like IPR008949, Isoprenoid_synthase_dom_sf IPR000092, Polyprenyl_synt IPR033749, Polyprenyl_synt_CS |
PANTHERi | PTHR11525, PTHR11525, 1 hit |
Pfami | View protein in Pfam PF00348, polyprenyl_synt, 1 hit |
SUPFAMi | SSF48576, SSF48576, 1 hit |
PROSITEi | View protein in PROSITE PS00444, POLYPRENYL_SYNTHASE_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q8II79_PLAF7 | |
Accessioni | Q8II79Primary (citable) accession number: Q8II79 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 1, 2003 |
Last sequence update: | September 22, 2009 | |
Last modified: | January 19, 2022 | |
This is version 114 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |