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Protein
Submitted name:

PeRoxireDoXin

Gene

prdx-2

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei49Cysteine sulfenic acid (-SOH) intermediateUniRule annotation1

GO - Molecular functioni

  • thioredoxin peroxidase activity Source: WormBase

GO - Biological processi

  • cell redox homeostasis Source: InterPro
  • determination of adult lifespan Source: WormBase
  • heat acclimation Source: WormBase
  • hydrogen peroxide catabolic process Source: WormBase
  • negative regulation of transcription by RNA polymerase II Source: WormBase
  • response to hydrogen peroxide Source: WormBase
  • response to metal ion Source: WormBase

Enzyme and pathway databases

BRENDAi1.11.1.15 1045
ReactomeiR-CEL-3299685 Detoxification of Reactive Oxygen Species
R-CEL-5628897 TP53 Regulates Metabolic Genes

Protein family/group databases

PeroxiBasei4485 Cel2CysPrx02

Names & Taxonomyi

Protein namesi
Submitted name:
PeRoxireDoXinImported
Gene namesi
Name:prdx-2Imported
ORF Names:CELE_F09E5.15Imported, F09E5.15Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome II

Organism-specific databases

WormBaseiF09E5.15a ; CE32361 ; WBGene00006434 ; prdx-2

Subcellular locationi

PTM / Processingi

Proteomic databases

EPDiQ8IG31
PeptideAtlasiQ8IG31

2D gel databases

World-2DPAGEi0020:Q8IG31

Expressioni

Gene expression databases

BgeeiWBGene00006434
ExpressionAtlasiQ8IG31 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliQ8IG31
SMRiQ8IG31
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 162ThioredoxinInterPro annotationAdd BLAST159

Phylogenomic databases

eggNOGiKOG0852 Eukaryota
COG0450 LUCA
GeneTreeiENSGT00390000004653
HOGENOMiHOG000022343

Family and domain databases

InterProiView protein in InterPro
IPR000866 AhpC/TSA
IPR024706 Peroxiredoxin_AhpC-typ
IPR019479 Peroxiredoxin_C
IPR036249 Thioredoxin-like_sf
IPR013766 Thioredoxin_domain
PfamiView protein in Pfam
PF10417 1-cysPrx_C, 1 hit
PF00578 AhpC-TSA, 1 hit
PIRSFiPIRSF000239 AHPC, 1 hit
SUPFAMiSSF52833 SSF52833, 1 hit
PROSITEiView protein in PROSITE
PS51352 THIOREDOXIN_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q8IG31-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKAFIGKPA PQFKTQAVVD GEFVDVSLSD YKGKYVVLFF YPLDFTFVCP
60 70 80 90 100
TEIIAFSDRA EEFKAINTVV LAASTDSVFS HLAWINQPRK HGGLGEMNIP
110 120 130 140 150
VLADTNHQIS RDYGVLKEDE GIAFRGLFII DPSQNLRQIT INDLPVGRSV
160 170 180 190
DETLRLVQAF QFVEKHGEVC PAGWTPGSDT IKPGVKESQE YFKKH
Length:195
Mass (Da):21,785
Last modified:March 1, 2003 - v1
Checksum:i493A2E078D016068
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284602 Genomic DNA Translation: CCD68767.1
RefSeqiNP_872052.1, NM_182252.5
UniGeneiCel.21965

Genome annotation databases

EnsemblMetazoaiF09E5.15a.1; F09E5.15a.1; WBGene00006434
F09E5.15a.2; F09E5.15a.2; WBGene00006434
GeneIDi266858
UCSCiF09E5.15b.1 c. elegans

Similar proteinsi

Entry informationi

Entry nameiQ8IG31_CAEEL
AccessioniPrimary (citable) accession number: Q8IG31
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: May 23, 2018
This is version 126 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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