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Protein

General transcription factor IIH subunit

Gene

PF3D7_1314900

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri304 – 321C4-typeUniRule annotationAdd BLAST18

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTranscription, Transcription regulationUniRule annotation
LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-PFA-6781823 Formation of TC-NER Pre-Incision Complex

Names & Taxonomyi

Protein namesi
Recommended name:
General transcription factor IIH subunitUniRule annotation
Gene namesi
ORF Names:PF3D7_1314900Imported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 13

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_1314900

Subcellular locationi

  • Nucleus UniRule annotation

GO - Cellular componenti

  • core TFIIH complex Source: InterPro
  • cytoplasm Source: GeneDB
  • holo TFIIH complex Source: GO_Central
  • nucleus Source: GeneDB

Keywords - Cellular componenti

NucleusUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ8IEG6
SMRiQ8IEG6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini85 – 261VWFAInterPro annotationAdd BLAST177
Domaini357 – 396RING-typeInterPro annotationAdd BLAST40

Sequence similaritiesi

Belongs to the GTF2H2 family.UniRule annotation

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri304 – 321C4-typeUniRule annotationAdd BLAST18

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

HOGENOMiHOG000280848
InParanoidiQ8IEG6
OMAiDCDIFIH
PhylomeDBiQ8IEG6

Family and domain databases

CDDicd01453 vWA_transcription_factor_IIH_t, 1 hit
Gene3Di3.30.40.10, 1 hit
3.40.50.410, 1 hit
InterProiView protein in InterPro
IPR007198 Ssl1-like
IPR004595 TFIIH_C1-like_dom
IPR012170 TFIIH_SSL1/p44
IPR002035 VWF_A
IPR036465 vWFA_dom_sf
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
PANTHERiPTHR12695 PTHR12695, 1 hit
PfamiView protein in Pfam
PF07975 C1_4, 1 hit
PF04056 Ssl1, 1 hit
PIRSFiPIRSF015919 TFIIH_SSL1, 1 hit
SMARTiView protein in SMART
SM01047 C1_4, 1 hit
SM00327 VWA, 1 hit
SUPFAMiSSF53300 SSF53300, 1 hit
PROSITEiView protein in PROSITE
PS50234 VWFA, 1 hit
PS50089 ZF_RING_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q8IEG6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQNPQNSENK VIFVEDVVRD FDENEIFEEI TGKFTWEQDV ERSWNLLVEN
60 70 80 90 100
NGVLQHVSQE NNENENKEKY RKNQGSSLRK GIFRHIIILF DMSSSMKERD
110 120 130 140 150
LKPDRINVAL ECVESFLKNF FFKNPVGHVG VVALKNSSAK LIQPFTSNVD
160 170 180 190 200
DILNSILKER TAGLQGSPSL EEGLQIAHDL LIDMPLYGTK EVLIMYGSIR
210 220 230 240 250
TCDKKNILNV LELLVKSNIY VNCISIAPEM HILKHICEKS NGFYKICSSK
260 270 280 290 300
NSLMNEINNN AETPLWMQGM EPQLIHICFP TKKKISTQIM CSCHGKLNTD
310 320 330 340 350
TYVCNFCNSY TCKIPSKCKV CGIHLISMHD LSHITNNLQG SPLFIEIKNE
360 370 380 390 400
QGNYKVCSSC NQQLYNKIYQ CTKCQHIFCL ECDIFIHEEL NQCPFCLIND

T
Length:401
Mass (Da):45,986
Last modified:March 1, 2003 - v1
Checksum:i879D34E8DD8BE71E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844509 Genomic DNA Translation: CAD52293.1
RefSeqiXP_001349885.1, XM_001349849.1

Genome annotation databases

EnsemblProtistsiCAD52293; CAD52293; PF3D7_1314900
GeneDBiPF3D7_1314900.1:pep
GeneIDi813966
KEGGipfa:MAL13P1.76

Similar proteinsi

Entry informationi

Entry nameiQ8IEG6_PLAF7
AccessioniPrimary (citable) accession number: Q8IEG6
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: July 18, 2018
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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