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Protein
Submitted name:

Bifunctional polynucleotide phosphatase/kinase

Gene

PF3D7_1363200

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

  • ATP binding Source: InterPro
  • ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity Source: GO_Central
  • damaged DNA binding Source: GeneDB
  • double-stranded DNA binding Source: GO_Central
  • polynucleotide 3'-phosphatase activity Source: GeneDB

GO - Biological processi

  • cellular response to DNA damage stimulus Source: GeneDB
  • DNA 3' dephosphorylation involved in DNA repair Source: GO_Central

Keywordsi

Molecular functionHydrolaseImported, KinaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Bifunctional polynucleotide phosphatase/kinaseImported (EC:2.7.1.78Imported, EC:3.1.3.32Imported)
Gene namesi
ORF Names:PF3D7_1363200Imported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 13

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_1363200

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Proteomic databases

PRIDEiQ8ID74

Structurei

3D structure databases

ProteinModelPortaliQ8ID74
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini303 – 368ATPase_AAA_coreInterPro annotationAdd BLAST66

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili260 – 280Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

HOGENOMiHOG000281734
InParanoidiQ8ID74
OMAiYGYRKQF
PhylomeDBiQ8ID74

Family and domain databases

Gene3Di3.40.50.1000, 1 hit
InterProiView protein in InterPro
IPR003959 ATPase_AAA_core
IPR036412 HAD-like_sf
IPR006549 HAD-SF_hydro_IIIA
IPR023214 HAD_sf
IPR027417 P-loop_NTPase
IPR013954 PNK3P
PfamiView protein in Pfam
PF00004 AAA, 1 hit
PF08645 PNK3P, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
SSF56784 SSF56784, 1 hit
TIGRFAMsiTIGR01662 HAD-SF-IIIA, 1 hit

Sequencei

Sequence statusi: Complete.

Q8ID74-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVKRNLPQFE LPNKNWNIFE DSLLYRIVKD KEDKIYKKIF SFDLDNTLIL
60 70 80 90 100
SRGFFKPAQN EKDYIFYSDI IEFLKKKHEE NYKIMIFSNQ KGVSSGKLSL
110 120 130 140 150
SNLINRVDDI IEKIGLPLEC YLALKNDKYR KPRIGMYLFA TQNYKQNLDE
160 170 180 190 200
VIYVGDNANR IYDEKFKQEF INHLKYIYSK NNVNININDI YKRLKKDYTD
210 220 230 240 250
TDLKFALNIN AKFYTPEDLF LNIKNHISTD FLFNPKYFNK ELNEQENINK
260 270 280 290 300
KNNHFYEICM KDYHSQNENI NNKKNNTNNN IIPNNQYTTN EKYIPPNDQQ
310 320 330 340 350
KLIILIGPPG CGKTFLCTNY FSTYIRINME EYKTISKCIQ VLKEKLLQRK
360 370 380 390 400
NVIIDNVNSL IKNRLLYINE AKKINQNIEI RLIYFNYSKE LIIHLNTFKL
410 420 430 440 450
ITDKTNKFND VPTIAIHSFY KYVQEPSKDE NVDHIIVLKD ENFVPTKFES
460
EEQKKLFFMY LN
Length:462
Mass (Da):55,334
Last modified:March 1, 2003 - v1
Checksum:iDD863622FFA89659
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844509 Genomic DNA Translation: CAD52753.1
RefSeqiXP_001350344.1, XM_001350308.1

Genome annotation databases

EnsemblProtistsiCAD52753; CAD52753; PF3D7_1363200
GeneDBiPF3D7_1363200.1:pep
GeneIDi814293
KEGGipfa:PF13_0334

Similar proteinsi

Entry informationi

Entry nameiQ8ID74_PLAF7
AccessioniPrimary (citable) accession number: Q8ID74
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: July 18, 2018
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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