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Entry version 87 (31 Jul 2019)
Sequence version 1 (01 Mar 2003)
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Protein
Submitted name:

Uncharacterized protein

Gene

PF3D7_0704800

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
PLASMO:PF07_0019-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:PF3D7_0704800Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPlasmodium falciparum (isolate 3D7)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri36329 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001450 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
PlasmoDB:PF3D7_0704800

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PRoteomics IDEntifications database

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PRIDEi
Q8IC22

PTM databases

SwissPalm database of S-palmitoylation events

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SwissPalmi
Q8IC22

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q8IC22

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni694 – 728DisorderedSequence analysisAdd BLAST35

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1202 – 1222Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi698 – 728PolarSequence analysisAdd BLAST31

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

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HOGENOMi
HOG000212964

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8IC22

Identification of Orthologs from Complete Genome Data

More...
OMAi
FNNYRFR

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001646 5peptide_repeat
IPR036457 PPM-type_dom_sf
IPR039123 PPTC7

The PANTHER Classification System

More...
PANTHERi
PTHR12320 PTHR12320, 1 hit

Pfam protein domain database

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Pfami
View protein in Pfam
PF13599 Pentapeptide_4, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF81606 SSF81606, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q8IC22-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEKLLHKCLH VNRSENGLDE EESVFQTCKI FVGLENEISE VNCIDNKNIG
60 70 80 90 100
NDFLCGFDNY AKKNCVEGIW MDELNGRKSG YMNLNEYYEN KFNIYFNIEN
110 120 130 140 150
IDYPLKFYKT IYFNFFSSFI ENEDREYILN ENINILNNFY ENIRNQKYLL
160 170 180 190 200
LHNAHSIPHE KKKINSNYKN GDAHMCSDNI ISIADGVSSI KNSGINVSNF
210 220 230 240 250
SNDLLKKCLN LHLYRCINKS LFEYQNDVIF KHYNLKYKDP EFLKPIICRS
260 270 280 290 300
ACSSNFLGAS TLLFASVEND KLHICTIGDC QMLIINLKEH YFKHKFFEKI
310 320 330 340 350
HIKVQTSKQM LCLQKRESNV TTIVDEEKEK FSGNIYNQIL NSNQNSIVEK
360 370 380 390 400
NYDNYKQSSS SLNFDMSDKK MDKENVNSWD DIIYDNSKSE LSKSESSKCK
410 420 430 440 450
SSNWELNKSD LDKAHLDKAD MNKAHLDKAD MNKAHLDKAD MNKADMNKAH
460 470 480 490 500
LDKAHLDKTH LTNSDLAKSE LTNSELAQSD LSKPSSVQSK IAISNITPSH
510 520 530 540 550
ILLEDSRNIN TNSVGSDKTY TDTNKSSISE LYLKRNKLCE NVLYSDINVN
560 570 580 590 600
MRVEESEETI LYVEYEINED IYEKFQKCLS ECDYKIGDLS FNLKEDNLYD
610 620 630 640 650
CSNIRSDTII SHNFSDTTEN DTSENEKNEK KYISGMTNTL DNEIGYRNLL
660 670 680 690 700
NFFQIDRNSI LKRKKNKYDE IWSNKVNLSY DWMNDLDNKE SNKLQEDKTE
710 720 730 740 750
LNNNTNGNNN NNNNNNSNNS NNNYNNSNNN NNNYYYYNSC KNKKNFNHYR
760 770 780 790 800
YRHDYEEECP FDIIHKSKIQ QHYFNCPYQI TFMPSNFSND NMKNKKSNNS
810 820 830 840 850
FNSTINMNKY NDIITKCLRY CDYSTIDLKN NYIIISGSDG LFDNLYDDDI
860 870 880 890 900
MKIIFNYFYI LKDNKFIKLK EFIKFNEEFK KAISWIYKTI SNSRDKDDTY
910 920 930 940 950
KEDIYFSKQS NDVYNKNLIK KKDTEEIDRN EFNRDLTKSE NSISEYEKGK
960 970 980 990 1000
GICIHGCHDQ NVCNNDNNIN CDKHHMNENN NEIIKKKGSN LFLNKFYSKG
1010 1020 1030 1040 1050
SFNSTMSKFN FVPKIKKIFS FKEKNKCDIK DQDKLNPSFS YLSNVTLNNT
1060 1070 1080 1090 1100
YEKQKEDSEH CNSMCDNKDL KKMNIPNFES ADTLKTDESF HVVRNDIRNM
1110 1120 1130 1140 1150
KYDKNYNKNN DMLNQQNTFD VISKTYDIKN DFSIDIELNN IRYNKKKRTF
1160 1170 1180 1190 1200
IIEKKIEAQN VLCNSSNLIL FDENMNIYLN TKKACDEIIE LSSILSNQQV
1210 1220 1230 1240 1250
NYSLLKKRRK KYNNDKENKK NKKKSFTASL FSNIQEKEKY LFDNINYDDI
1260 1270 1280 1290
QSNKSNDKII LTPISEFIFD KYKKYFNMGK PDDTTVIVSI VKENKYI
Length:1,297
Mass (Da):152,656
Last modified:March 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i25DB06823C2E8643
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL844506 Genomic DNA Translation: CAD50819.1

NCBI Reference Sequences

More...
RefSeqi
XP_001348981.1, XM_001348945.1

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
CAD50819; CAD50819; PF3D7_0704800

GeneDB pathogen genome database from Sanger Institute

More...
GeneDBi
PF3D7_0704800.1:pep

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
2655055

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
pfa:PF3D7_0704800

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844506 Genomic DNA Translation: CAD50819.1
RefSeqiXP_001348981.1, XM_001348945.1

3D structure databases

SMRiQ8IC22
ModBaseiSearch...

PTM databases

SwissPalmiQ8IC22

Proteomic databases

PRIDEiQ8IC22

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiCAD50819; CAD50819; PF3D7_0704800
GeneDBiPF3D7_0704800.1:pep
GeneIDi2655055
KEGGipfa:PF3D7_0704800

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_0704800

Phylogenomic databases

HOGENOMiHOG000212964
InParanoidiQ8IC22
OMAiFNNYRFR

Enzyme and pathway databases

BioCyciPLASMO:PF07_0019-MONOMER

Family and domain databases

InterProiView protein in InterPro
IPR001646 5peptide_repeat
IPR036457 PPM-type_dom_sf
IPR039123 PPTC7
PANTHERiPTHR12320 PTHR12320, 1 hit
PfamiView protein in Pfam
PF13599 Pentapeptide_4, 1 hit
SUPFAMiSSF81606 SSF81606, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ8IC22_PLAF7
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8IC22
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: July 31, 2019
This is version 87 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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