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Entry version 76 (31 Jul 2019)
Sequence version 1 (01 Mar 2003)
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Protein
Submitted name:

Uncharacterized protein

Gene

PF3D7_0715200

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
PLASMO:PF07_0061-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:PF3D7_0715200Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPlasmodium falciparum (isolate 3D7)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri36329 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001450 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
PlasmoDB:PF3D7_0715200

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 18Sequence analysisAdd BLAST18
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500431002019 – 2206Sequence analysisAdd BLAST2188

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q8IBU8

PTM databases

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q8IBU8

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q8IBU8, 1 interactor

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q8IBU8

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni45 – 68DisorderedSequence analysisAdd BLAST24
Regioni395 – 426DisorderedSequence analysisAdd BLAST32
Regioni660 – 754DisorderedSequence analysisAdd BLAST95
Regioni861 – 888DisorderedSequence analysisAdd BLAST28
Regioni1094 – 1127DisorderedSequence analysisAdd BLAST34
Regioni1825 – 1894DisorderedSequence analysisAdd BLAST70

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili2019 – 2039Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi396 – 425PolyampholyteSequence analysisAdd BLAST30
Compositional biasi664 – 706PolyampholyteSequence analysisAdd BLAST43
Compositional biasi707 – 754PolarSequence analysisAdd BLAST48
Compositional biasi1850 – 1866PolyampholyteSequence analysisAdd BLAST17
Compositional biasi1867 – 1894PolarSequence analysisAdd BLAST28

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis, SignalSequence analysis

Phylogenomic databases

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8IBU8

Identification of Orthologs from Complete Genome Data

More...
OMAi
TTIAYDS

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q8IBU8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSHNPASILL FTVQGLLASL TCGLCCYLYS YCYNGRFFKN GRGSNRNNKK
60 70 80 90 100
RSISSVEGDF PNSKKCKKGH INHECSNNKE ENKILIKEDE YETYDTYKTH
110 120 130 140 150
DIYKTYDTYK THDIYETYDT YKTHDIYETY DTYKTHDTFK THDTFKTYDK
160 170 180 190 200
YDGYILPNDV TKYDSNYLEN LLKENNKVSL ISERREQIIR DIINDYKNIT
210 220 230 240 250
TTYNINIQGD NNIYNYYNKY VLPYFLNNNE NDIYDEDNCK VLNPYEKIDK
260 270 280 290 300
HFDEKLKEFK YKMIQEQIDN YFHDVHEKDH NNVNSSNLIV EKNLLLNNNN
310 320 330 340 350
NNNNNNNCVY HKESTPYKNN NNLHNQVNTP RDEGYKHNNN YYNNIINENM
360 370 380 390 400
YFKQKDDKNI VLTQNMKNNH HNYSDNNIST HEKNYNLIHE QTNKNSQENK
410 420 430 440 450
SLEENKKNNL HPSNVHKDKC NIKNDVSDTS NEQKFVLIRS NEKEEINNNI
460 470 480 490 500
IREDIIKEDI KEDIIKENVK EDIIKEDIKE DIIKENVKED IIEEDIKEDI
510 520 530 540 550
IKENVKEDII EEDIKEDIIK EDVKEDIIKE NVKEDIIEED IKEHIIEEDI
560 570 580 590 600
KEHIIEEDIK EHIIEEDIKE HIIDKCVEQD IINRNISNEI NNSYLLNENI
610 620 630 640 650
DKIKTSKEGS HEERPRTVLK QIPANISCCP INSIEQEKYN NDDSLKSTLS
660 670 680 690 700
CSVNNNNMKK KTTLKLSEPS EEVNMNKQKK ENETEKIKGN KIECERKNRR
710 720 730 740 750
VSEQIDDNDN NNNNNNNNNN NNNSNNNNNN NNNNNNNNNN NNNNSNNNFN
760 770 780 790 800
SNNNVVLPNN NYLLNNKLCI PIDDEYIKKI RNEQTDTFLQ KLIMEYYDER
810 820 830 840 850
KRRTFFDDTI KGNIYYVNDY EEYREEFESN RTKIGDLQNF DKFILPNQFI
860 870 880 890 900
LSSNETDINE NKYNDIKSSN TKNNDQQNKN VNKHNNNNNK LIHITTLENN
910 920 930 940 950
NKNVTLKEGQ HIHISKDSMH ISNKKNIKHT VECDEDNFLS YKNKIKNDIL
960 970 980 990 1000
QELVNKSFNS NSINDIYNNK ENKIELNDSH LKHCEVNISN NMREYNQSRN
1010 1020 1030 1040 1050
MEHVNVLVHM NNNNDKDKNN NERNNNVCNL KNISSFNVNT MNNMINNNNN
1060 1070 1080 1090 1100
NNNNNINFNS PNKYYNFNNI NGEFSLNDDR RNKGNIPFDM NLTNDISKNN
1110 1120 1130 1140 1150
NNNNNNNNNN NNNNNNNNNN NNNNNKIMDT SLKSMRAVSL SSLQKLILEH
1160 1170 1180 1190 1200
NKILREKHNH KITQIGNQDN CIFKISESAE SENENNEHNN NNNLNIIHSI
1210 1220 1230 1240 1250
NNTNNIHFPN NKVNTFVSNK TNVNMNNITN INMNNVINSI LNNAANNNMN
1260 1270 1280 1290 1300
NAPTNVMHNT SNSLMNNAPT NVINNTSNSL MNNAPTNVIN NTSNSLMNNA
1310 1320 1330 1340 1350
PTNVINNTSN NLMNNAPTNV INNTSNSLMN NAVSQLINNG TNHMINNGTN
1360 1370 1380 1390 1400
HMMNNILNSL INNNNMMMMN IPVDIDKNSK VFKNIENEEP VLQNLSDIQK
1410 1420 1430 1440 1450
LLLHKGSNPY MFNNLRISNN LNNDKNSNVN SFIKMNNVGE NISTCQHNNN
1460 1470 1480 1490 1500
NYMVNITTSQ PRYNCINRYN VPKDYEENKD INKKSNVIKK VDNEKCYTID
1510 1520 1530 1540 1550
EKYGGPYNNC ENVNDMKHRR GNSNCSNTNN NKDNKDNYGN YGNYDNYDNN
1560 1570 1580 1590 1600
NNNYMNYHNN NINDYANHHF NKQHVNTIRE GFDTYILIDD DNDNDTDIST
1610 1620 1630 1640 1650
DKRNNPLNRN NKKMNLKCNL NKLPNITNNE KHKNEKNISR TKYVCLGLKR
1660 1670 1680 1690 1700
NSRENIHHMN NEENEINLEM INDYHQNKQV KDIISTYIHT SKIQYETKKG
1710 1720 1730 1740 1750
KDISNNNYMN VQKIQTTHGN YPHKIGDINI QENYRNVVQN RNMNNNSSFA
1760 1770 1780 1790 1800
ENIGRILTRS SSQQKDIHAL EKEIGNVQND KSIYYNNTVN RWNDEVVFIC
1810 1820 1830 1840 1850
TNENEDKNDS ANSLRKEKKN GTLLYAKEKE EENNTETQNV RRSVRLHNKK
1860 1870 1880 1890 1900
VKNETKNREI EKKNNISNNN RSKNNRSNNS KSNNTRANNN RTIDNEPVVK
1910 1920 1930 1940 1950
ESIVNESVVK EYVVKEYVVN ESITNESITN ESITNESITN ESIMNESITS
1960 1970 1980 1990 2000
EQSNKSIEKN SFEKSYSVEV VSLNDSTDIN ENPRNLENKN APLKNVKMFE
2010 2020 2030 2040 2050
KKVSETPAME LRLSKKHSLL KKRENLEMLH QKCNEIDENK CASGFVNYIL
2060 2070 2080 2090 2100
QNIQKRDGKE TFDDLLNYIL KLKEIYNMST MDFIGAFLIL ESFNLNIINE
2110 2120 2130 2140 2150
YPLREWILVT FHYIKGMITL QNIKFIIKSL DLNHLIISNI TAAFYMNIKP
2160 2170 2180 2190 2200
IKVDEENIER VLNLLSEVVI RRSSRFKLLK TDTEKQNQQD EKLGSCWQPV

HTIKDS
Length:2,206
Mass (Da):258,401
Last modified:March 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD4ED711AE470383C
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL844506 Genomic DNA Translation: CAD50900.1

NCBI Reference Sequences

More...
RefSeqi
XP_001349055.1, XM_001349019.1

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
CAD50900; CAD50900; PF3D7_0715200

GeneDB pathogen genome database from Sanger Institute

More...
GeneDBi
PF3D7_0715200.1:pep

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
2655105

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
pfa:PF3D7_0715200

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844506 Genomic DNA Translation: CAD50900.1
RefSeqiXP_001349055.1, XM_001349019.1

3D structure databases

SMRiQ8IBU8
ModBaseiSearch...

Protein-protein interaction databases

IntActiQ8IBU8, 1 interactor

PTM databases

SwissPalmiQ8IBU8

Proteomic databases

PRIDEiQ8IBU8

Genome annotation databases

EnsemblProtistsiCAD50900; CAD50900; PF3D7_0715200
GeneDBiPF3D7_0715200.1:pep
GeneIDi2655105
KEGGipfa:PF3D7_0715200

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_0715200

Phylogenomic databases

InParanoidiQ8IBU8
OMAiTTIAYDS

Enzyme and pathway databases

BioCyciPLASMO:PF07_0061-MONOMER

Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ8IBU8_PLAF7
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8IBU8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: July 31, 2019
This is version 76 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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